ppt bab 4 5
-
Upload
dwi-yuliannisa-amri -
Category
Documents
-
view
230 -
download
0
description
Transcript of ppt bab 4 5
Patient CharacteristicsFactors No. Of patients Percentage Age<60 tahun 22 73,3 %≥60 tahun 8 26,7 %SexMale 16 53,3 %Female 14 46,7 %
Association between HIF-1α and Patient Characteristics
FactorsHIF-1α (+) HIF-1α (-)
Exact Sig. (2-sided)
Exact Sig. (1-sided)n (%) n (%)
Age
<60 6 20,0% 16 53,3%1,000 0,645
≥60 2 6,7% 6 20,0%
Sex
Male 3 10,0% 13 43,3%0,417 0,263
Female 5 16,7% 9 30,0%
Positive expression
Immunohistochemical staining of HIF-1α in well differentiated colon adenocarcinomas
Factor
HIF - 1α (+) HIF - 1α (-)Asymp. Sig. (2-sided)n % n %
Differentiation Grade
Well 2 10,5 % 17 89,5 %
0,081Moderate 3 42,9 % 4 57,1 %
Poor 3 75 % 1 25 %
Statistical analyses showed no significant difference between the expression of Hypoxia Inducible Factor (HIF) 1-α on the degree of differentiation in colorectal cancer tumors with p = 0.081.
Positive expression of HIF-1-α most founded in moderate and poor differentiation with each totaling 3 slides.