Poossttggrraad duuaattee...
Transcript of Poossttggrraad duuaattee...
FFaaccuullttyy ooff MMeeddiicciinnee AAiinn SShhaammss UUnniivveerrssiittyy
PPoossttggrraadduuaattee SSttuuddiieess
Master of Science in Medical Biochemistry and Molecular
Biology
انكييبء انحيىيت انطبيت و انبيىنىجيب انجزيئيت درجت انبجسخيز في
Program Code: BM600
Program Guide and
Logbook
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C a n d i d a t e C u r r i c u l u m v i t a e
[Name]
Please attach your recent photo photo here.
[telephone no]
[mobile no]
[mailing address]
[email address]
[postcode]
Experience
[organization]
[your present job title]
[start date]
[location]
[responsibilities]
[organization]
[previous job title]
[start and end date]
[location]
[responsibilities]
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[organization]
[start and end date]
[location]
[responsibilities]
Education
[certificates]
[start and end date]
[school or college]
Training
[any other training that will be useful in your job]
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Filled by post graduate authorities
Date of Registration
First semester _______________________
Second semester _______________________
Third semester _______________________
Fourth semester _______________________
TABLE OF CONTENTS: Page
I – Welcome Statement
II - Mission Statement
III – Senior supervisor and affiliated departments and Hospitals
IV – Program specifications
1 - Basic Information
2 - Professional Information
3 – Academic standards
4 – Curriculum structure and contents
5 - Program courses:
6. Program admission requirements:
7. Regulation for progression and program completion
8. Appendix: course specifications:
Immunology course specification
Phrmacology course specification
Physiology course specification
Practical Biochemistry coursespecification
Medical Biochemistry course specifications
Molecular Biology course specifications
Bioinformatics course specifications
Statistics course specifications
V - General information
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VI – Your log book
1 – Introduction
2 – Supervisors
3 - Tables for training records
4 – Log book preview
VII - Head of department approval for the exam entry
Detachable forms:
VIII – Thesis follow up
IX - Evaluation forms
I – Welcome Statement:
The Department of Medical Biochemistry and Molecular Biology welcomes
you to the Degree of Master of science in Medical Biochemistry and Molecular
Biology. As a department we are committed to medical student education and
continuously strive to improve your educational experience.
This handbook presents information guide and logbook activity of this
master degree administered by Medical Biochemistry and Molecular Biology
Department, Faculty of Medicine, Ain Shams University.
II - Mission Statement:
The mission of the Faculty of Medicine, Ain Shams University is “The
preparation of a competent graduate, who is able to compete on both national
and regional levels, capable of lifelong learning, training and tutoring, while
adhering to the codes of practice of medical health services and ethics. The
college as well, seeks continuous development of programs and courses. It also
enhances expansion of applied scientific research and health programs for
community services and environmental development. Moreover, through
providing distinguished academic and research cadres of teaching staff,
supporting the administrative system and sustainability of own resources, the
college is able to achieve goals and objectives”. The mission of this degree is
To provide postgraduate students with a basic understanding of the biological
processes in humans at a molecular level and to correlate any molecular defect or
abnormality to medical problems
To provide postgraduate students with advanced information concerning human
genetics and the future of diagnostic and therapeutic tools.
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To provide the environment necessary to develop skills in self-evaluation, self-
directed learning and critical appraisal enabling the medical biochemist to adapt to
the rapid progress of information and changes that will occur in the profession
throughout their careers.
To provide the postgraduate students with the opportunity to become competent
medical biochemists with the skills required to a professional of medical
biochemistry laboratory.
III – Senior Supervisor and Affilated Departments and Hospitals
Senior Supervisor
Prof.
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E-mail:
Affilated Departments and Hospitals
Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine,
Ain Shams University.
IV – Program Specifications
A- Basic Information
1. Program title:
Master of science in Medical Biochemistry and Molecular Biology
2. Progm type:
Single Double Multiple
3. Faculty
Ain Shams University – Faculty of medicine
4. Department
Medical Biochemistry and Molecular Biology
5. Assistant coordinator:
Professor Samar Kamal Kasim
Professor of Medical Biochemistry and Molecular Biology
6. Coordinator:
Professor Noura Elkholy
Professor of Medical Biochemistry and Molecular Biology
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7. Last date of program approval:
B- Professional Information:
1. Program aims:
To provide postgraduate students with a basic understanding of the biological
processes in humans at a molecular level and to correlate any molecular defect or
abnormality to medical problems
To provide postgraduate students with advanced information concerning human
genetics and the future of diagnostic and therapeutic tools.
To provide the environment necessary to develop skills in self-evaluation, self-
directed learning and critical appraisal enabling the medical biochemist to adapt to
the rapid progress of information and changes that will occur in the profession
throughout their careers.
To provide the postgraduate students with the opportunity to become competent
medical biochemists with the skills required for a professional of medical
biochemistry laboratory.
2. Intended learning outcomes (ILOs):
a. Knowledge and understanding:
By the end of this program the student should be able to:
A1- Describe the structure function relationship of some important proteins:
hemoglobin, myoglobin, skeletal muscles, collagen, and immunoglobulins.
A2- Explain the methods of classification and regulation of enzymes as well as
kinetics of enzymes and coenzymes.
A3- Describe the structure of DNA and RNA as well as the processes of
replication, transcription, translation, regulation of gene expression, and methods
of in vivo and in vitro amplification of DNA.
A4- State the characteristics of the genetic code and the relation of various types of
mutations to genetic diseases and cancers.
A5- Describe the biochemical basis of cancer, gene therapy, stem cell therapy, and
various techniques of genetic testing.
A6- Describe the structure of biological membranes and classify the different
mechanisms of signal transduction across membranes
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A7- Describe the metabolic pathways of carbohydrates, lipids, and proteins, their
energetics, their sites, the ways of their regulation and possible metabolic errors.
A8- Describe the components of mitochondrial ETC and their inhibitors.
A9- Describe the composition of blood and explain the mechanism of blood
clotting, anticoagulation and fibrinolysis.
b-Intellectual Skills:
By the end of the course, students should be able to:
b1- Integrate basic biochemical facts with clinical diseases.
b2- Analyse and interpret different spectrophotometric data and use them in
diagnosis of a clinical case.
B3- Interpret the results of molecular biology techniques.
B4- Identify electrophoretic bands, interpret disease-associated changes in plasma
proteins and diagnose sickle cell trait and sickle cell anemia
B5- Retrieve and analyze nucleic acids and proteins data (bioinformatics)
B6- Differtiate between inherited and aquired hypercoagulable states
B7- Solve any subject-related problems provided by staff
B8- analyze laboratory data using statistical rules.
a- Professional and Practical Skills: By the end of the course, students
should be able to:
c1- Prepare solutions of acids, bases, and buffers and adjust their concentration and
pH
c2- Use spectrophotometric assay methods to determine the concentration of
substances in biological fluids
c3- Extract DNA, amplify a certain sequence of DNA by PCR and interpret results
of DNA fingerprinting
C4- Prepare buffers and make dilutions of known concentration.
C5- Purify proteins by molecular sieving, by ion exchange or affinity
chromatography and check protein purity.
C6- Perform different types of assays as ELISA, immunodiffusion.
C7- Perform different types of electrophoretic techniques.
d- General and Transferable Skills: By the end of the course, students
should be able to:
d1- Work in a team in the lab and cooperate with their colleagues and staff.
d2- Use basic computing skills and internet to fulfill problem-based learning
d3- Communicate relevant information with teaching staff and colleagues
d4- Recognize and effectively deal with unethical behavior of other members of
lab team.
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D5-Understand the importance of life-long self-learning and show a strong
commitment to it.
3. Academic standards: (Benchmarks)
University of Vermont, Burlington, USA, Graduate College, Department of
Biochemistry
Contact Email: E-mail:[email protected]
Website: http://www.uvm.edu
4. Curriculum structure and contents:
4 a- Program duration: two years (4 semesters)
4b- Program structure:
اننبهج
انكىد انقزراث انذراسيتانسبعبث
انعخذة
دورة أسبسيبث انبحث انعهي يخطهببث انكهيت
لانجزء األو BM6001 4 االدويت أو–انفسيىنىج أو–انبكخزيب
BM6002 2 فخزة حذريبيت عهيت ف انكييبء انحيىيت
6 انزسبنت
انجزء انثبني
BM6003 21 انكييبء انحيىيت انطبيت
BM6004 3 انبيىنىجيب انجزيئيت
BM6005 2 دراست عهيت و حطبيقيت
االخخيبريت انقزراث
يبدة واحذة ين : يخخبر انطبنب
E6009 اإلحصبء -
E6018يقبث انبيى يعهىيبحيت طبح –
E6009
E6018
2
6 كزاست األنشطت
36 انجىع
5. Program courses:
a. Compulsory
Code Course title
L P SDL
10
BM6001(a)
BM6001(b)
BM6001(c)
Bacteriology &immunology
Or Pharmacology
Or Physiology
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12
BM6002
Practical Biochemistry Course
60
BM6003 Medical Biochemistry 150 60
BM6004
Molecular Biology
30
30
BM6005 Practical and applied Biochemistry
(Cases and problem solving) 30
L: Lecture, P: practical and SDL: Self directed learning
b. Elective
Code Course title No. of hours
L P SDL
E6009 Statistics 15
E6018 Bioinformatics 15
6. Program admission requirements:
-( : يشترط لقيد الطالب للحصول على درجة الماجستير:6) المادة عمى درجة البكالوريوس في الطب والجراحة من إحدى جامعات جميورية - 1 أن يكون حاصال
موافقة جية العمل -3 أن يكون قد أمضى سنة التدريب )االمتياز( -2 مصر العربية أو عمى درجة معادلة
-5( 1ريف التدريب واستيالك األجيزة واستيفاء المستندات المطموبة في الممحق )تسديد الرسوم ومصا -4 التفرغ لمدراسة لمدة فصمين دراسيين قبل دخول امتحان الجزء الثاني
-الماجستير األوراق التالية :ة يقدم طالب اإللتحاق لدرج ( :1ملحق ) -5 شبيادة المبيالد أو مسبتخرج رسبمي -4 يبازشبيادة اإلمت -3 شبيادة البكبالوريوس -2 طمبب إلتحباق -1
صبور فوتوررافيببة 6عبدد -7 موافقببة جيبة العمبل عمبى التسبجيل والتفبرغ المطمببوب -6 الموقبف مبن التجنيبد بالنسبة لموافدين يقدم الطالب موافقة السفارة ويحدد جية تحمل النفقات كما يقدم شيادة صحية -8 جديدة
7. Regulation for progression and program completion
يببتم التسببجيل لمماجسببتير مببرة واحببدة فببي السببنة تبببدأ مببن أول يوليببو حتببى أخببر أرسببطس (: 8مااادة )ويجبوز قببول تسبجيل النبواب والمعيبدين والوافبدين فبي الفتبرة عمى أن تبدأ الدراسة في شير أكتوبر من كل عبام
دخول إمتحان الجزء األول إال بعد إنقضاء فتبرة الدراسبة من أول نوفمبرحتى أخر ديسمبر عمى أال يسمح ليم ب .المطموبة
تببوزا الدراسببة فببى كببل عببام جببامعى عمببى فصببمين دراسببيين مببدة كببل منيمببا خمسببة عشببر (: 9مااادة )اسبببوعا ي يبببدا االول فببى أول أكتببوبر ويبببدا الثببانى فببى منصببف فبرايببري مببف تنكببيم فصببل دراسببى صببيفى مكثببف
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تم التسببجيل لمفصبل الدراسببى قبببل اسببوعين مببن بدايتبو عمببى االقببل بعبد إسببتيفاء الشببروط لمبدة سببتة اسبابيف ي و يببسببباعات معتمبببدةي 6حسبببب المقبببررات المسبببجمةي والينبدبببى أن يزيبببد العببببء الدراسبببى فبببى الفصبببل الواحبببد عبببن
جبوز ويجوز لمطالب تعبديل المقبررات خبالل اسببوعين مبن بدايبة الفصبل الدراسبى )بالحباف او االضبافة(ي كمبا ي لو االنسحاب خالل ستو اسابيف من احد المقرارت دون احتسابو راسبا فيوي
: مدة الدراسة لمحصول عمى درجة الدبموم أو الماجستير ىى أربعة وعشرون شيرا ( 11المادة ) )أربعة فصول دراسية( عمى جزئين يجتاز فييا الطالب برنامجا تدريبيا متكامال طبقا لمساعات المعتمدة
وال يسمح لو بدخول األنشطة الموضحة بالباب الرابف ويستوفى خالليا المطموب منة فى كتيب متابعة اإلمتحان قبل إستيفاء ثالثة أرباا المطموب منة في كل جزء من البرنامج
يجتاز بعدىا واحد الدبموم والماجستير الجزء األول فصل دراسي فيمدة الدراسة ( :11المادة )ب إمتحانا وال يشترط النجاح فيو بالكامل لإلنتقال لمدراسة في الجزء الثانيي والجزء الثاني يتطمب تفرغ الطال
يبأحد المستشفيات أو المراكز المعتمدة من الكمية لمدة فصمين دراسيين لمتدريبالطالب ي أو يقوم الدارس لدرجة الماجستير بتسجيل موضوا الرسالة عمى شكل بحث نكر ( : 11مادة )
عمى من التسجيل عممي بعد إستيفاء فصل دراسي واحد عمى األقل ويجوز أن يناقش رسالتة بعد ستة شيور صاألقل عمى أن يكون قد نجح فى مقررات الجزء األول بالكامل وقبل دخول إمتحان الجزء الثاني وال يخص
تليا درجامعة قبل تسجيل الرسالة ومتطمبات يقوم دارس الماجستير بإستيفاء متطمبات الجا( : 11مادة )
متطمبات الجامعة ىي الحصول عمى شيادة التويفل في المدة و يالكمية قبل دخول إمتحان الجزء الثانيدرجة عمى األقل( ومتطمبات الكمية ىي حضور دورات معتمدة من لجنة الدراسات 454اإلنجميزية بمجموا )
واإلحصاء الطبى أو بإجتياز إختبارات خاصة تحددىا المجنةي مىمناىج البحث العمالعميا بالكمية في مجال يجوز لمحاصمين عمى درجة الدبموم إستكمال درجة الماجستير بتسجيل رسالة (: 11مادة )
الماجستير خالل أربف سنوات من الحصول عمى درجة الدبموم ويحصل عمى الدرجة بعد إستيفاء متطمبات الة بنجاحي الجامعة والكمية ومناقشة الرس
الساعات المعتمدة لدراسة الدبموم والماجستير ثالثون ساعة معتمدة عمى األقل (: 16مادة )وتشمل ست ساعات عمى األقل لمجزء األول وثماني متابعة األنشطة يخصص منيا ست ساعات لكتيب ويضاف إلييا ست ساعات لمرسالة فى الماجستيري عشرة ساعة عمى األقل لمجزء الثاني
يلماجستير أربف سنواتامدة القيد لدرجة (: 11مادة ) درجة لمجزء 344درجة منيا 1244مماجستير لمجموا درجات االمتحان النيائى (: 11مادة )
يمماجستيردرجة ل 344يوازى مى التراكمى بما صاألولي ويضاف الييا المعدل الفمن كل عام ويعقد إمتحان الدور الثاني يعقد إمتحان الدور األول في أكتوبر ونوفمبر (: 11مادة )
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فى أبريل ومايو من كل عامي % من 64يكون النجاح فى كل مادة من الدبموم العالى والماجستير بعد الحصول عمى (: 16مادة )
% من درجة64الدرجة الكمية لكل لجان المادة مجتمعة ويكون النجاح فى مواد الدكتوراه بعد الحصول عمى ممي واالكمينيكى والشفوي كل عمى حدةيالتحريري والع
(: فبى حالببة إسببتنفاا مبدة القيببد يمكببن لطالبب الدراسببات العميببا إعبادة التسببجيل مببرة أخببرى وال 19)مااادة يعتد بالنجاح فى الجزء األول أو الرسالة ويجب إعادتيماي
Assessment Schedule and Weighing of Assessments
Item Mark
Po
ints
GP
A s
core
ةطان
اننححا
Stu
den
t
sta
te
During
semester
End of
semester Total
First semester (If present) 100 300 400
Second semester 100 100
Third semester 100 100
Fourth
semester
Final exam
Written
900 900
Oral
Practical
/Clinical
Total 300 1200 1500
عه انىج انتان:يهحىظح: تعادل درجاخ انطانة طثقا نهقاط
نقبط 4 : % فأكثز 09 -2 A
نقبط 3663 : % 09% حخ أقم ين 55ين -1 A-
نقبط 3633 : %55% حخ أقم ين 59ين - 3 B+
نقبط 3699 : %59حخ أقم ين %35ين - 4 B
نقبط 1663 : %35% حخ أقم ين 39ين - 5 B-
نقبط 1633 : %39% حخ أقم ين 65ين - 6 C+
نقبط 1699 : %65% حخ أقم ين 61ين -3 C
نقبط 2663 : %61% حخ أقم ين 69ين - 5 C-
F صفز : %69أقم ين - 0
درجح نهجسء 011درجح يها 0011يجىع درجاخ االيتحا انهائ نهدتهىو انعان واناجستير
درجح نهجسء األول إ وجد. 011درجح يها 0011األول ويجىع درجاخ االيتحا انهائ نهدكتىرا
درجح 011دتهىو انعان واناجستير ودرجح نه 011ه انتراك تا يىازي صويضاف إنيها انعدل انف
.نهدكتىرا
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( عهى ساىاش يجىىع حاضىم نىرب قىاط كىم يقىرر يضىروتا GPAويتى حساب انعدل انفصه )
ف عدد ااعات انعتدج يقسىيا عه انساعاخ انعتدج نهقرراخ انت دراىها انطانىة فى انفصىم اندرااى.
( عهى ساىاش يجىىع حاضىم نىرب انقىاط انتى حصىم CGPAانعدل انتراك نهطانة ) كا يتى حساب
عهيها انطانة ف كم يقرر يضروتا ف عدد ااعات انعتدج يقسىيا عه يجىع انساعاخ انعتدج انكهيح.
يىىتى سو انىىدكتىرا واناجسىىتير فىى انىىدتهىو سقىىرراخ انفىى حانىىح انراىىىب فىى يىىادج سو يجىعىىح يىى
ويتى حساب انتقىدير انفعهى انىيي يحصىم عهيى فى سول إعىادج فقىظ سيىا إ ا ىعح فقظ. اإلعادج ف انادج سو انج
قاط اي 0.01% فقظ )اي01تكرر راىتح فيحسة ن عد انجاح تقدير -
C)6
Microbiology and Immunology course specification University: Ain Shams University Faculty: of Medicine
Course specifications
Program on which the course is given: Master degree in Medical Biochemistry
and Molecular Biology.
Major or minor element of programs: Major
Department offering the program: Medical Biochemistry and Molecular
Biology.
Department offering the course: Microbiology and Immunology Department.
Academic Level: Master – 1st semester
Date of specification approval: …………………………..
A- Basic Information
Title: Microbiology and Immunology course Code: BM6001(a)
Credit Hours: hour Lecture: /week Total:
Coordinator
Microbiology and Immunology Department.
B - Professional Information 1- Course Aims:
The overall aim of the course:
1. To introduce the candidate to bacterial and viral genetics
2. To enable the candidate to cope with the international standards of
Immunology.
Intended Learning Outcomes:
a- Knowledge and understanding:
At the end of the course the candidate will be able to:
a1- Describe bacterial genetics and antimicrobial drugs
a2- Undestand viral structure, classification, and genetics
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a3- Understand the natural defense mechanisms.
a4- Define the terms, antigens, hapten.
a5- Recognize the factors affecting immunogenicity of antigens
a6- Understand the phenomenon of self and non-self recognition by the immune
system.
a7- Describe the two limbs of the immune response (namely, antibody mediated
and cell mediated )
a8- Understand how active and passive immunity can be acquired and to know the
indications for immunization.
a 9- Define the term antibody and to know the structure and biological functions of
each class of immunogobulins
a10- Understand the nature of the Ag-Ab interaction and its in vitro applications in
the diagnostic microbiological lab.
a11- Understand the cellular cooperation and interaction in an immune response
and the different mediators involved in immunoregulatory mechanisms
a12- Understand the immunological processes underlying protection against
microbial disease and tumors.
a13- Explain the beneficial role of the immune system in protection against
microbial infections and development of tumors.
a14-Discuss means and types of immunization against medically important
microorganisms.
a15- Explain the detrimental role of the immune system in hypersensitivity
reactions, transplant rejection and development of autoimmune diseases.
a16- Understand the concept of immune deficiency diseases
b- Intellectual Skills:
By the end of the course, students should be able to: b1- Integrate basic immunological facts with clinical diseases.
b2- Classify oncogenic viruses that place individuals at risk of malignancy
b3- Demonstrate abilities to retrieve, analyze, evaluate, and present scientific
information by involvement in problem solving activities.
c- Professional and Practical Skills:
By the end of the course, students should be able to:
C1- Use informational technologies and library resources in the field of
immunology and microbiology.
C2- Communicate information with teaching staff and collegues
C3- Use the internet to retrieve and to present information.
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C4- Apply safety measures in the laboratory to prevent contamination of the lab
and equipments.
d- General and Transferable Skills:
By the end of the course, students should be able to:
d1- Adopt the principles of life-long learning
d2- Retrieve, manage, and manipulate information by all means, including
electronic means.
d3- Present information orally, electronically, or by written means
d4- Effectively manage time and resources and set priorities
d5- Work in a team in the lab. and cooperate with colleagues and staff.
D6- Utilize problem solving skills in a variety of theoretical and practical
situations.
Contents of the course:
No. of hours
L T C/
P
SD
L
General bacteriology:
10 8
Virology:
1- Viral structure
2- Classification of viruses
3- Viral replication
4- Viral genetics.
10
Immunology:
I. THE INNATE IMMUNE SYSTEM
A. The Innate Immune System: An Overview
B. Pathogen-Associated Molecular Patterns
(PAMPs), Pattern-Recognition Receptors
(PRRs), and Cytokines
C. Cells Involved in Body Defense
D. Anatomical Barriers, Mechanical Removal,
Intraepithelial T-Lymphocytes and B-1 Cells,
Bacterial Antagonism by Normal Flora, and
35 4
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Antigen-Nonspecific Antimicrobial Chemicals
Produced by the body
E. The Complement System :
F. Phagocytosis
G. Natural Killer (NK) Cells
H. Inflammation
I. Nutritional Immunity
J. Fever
K. The Acute Phase Response
II. ADAPTIVE IMMUNITY
A. Overview of Adaptive Immunity
B. Major Cells and Key Cell Surface Molecules
Involved in the Immune Responses
C. The Lymphoid System
D. An Overview of the Steps Involved in Adaptive
Immune Responses
IIa. HUMORAL IMMUNITY
A. Antibodies (Immunoglobulins)
B. Ways That Antibodies Help to Defend the Body
C. Naturally and Artificially Acquired Active and
Passive Immunity
D. Monoclonal Antibodies
IIb. CELL-MEDIATED IMMUNITY
A. The Steps Involved in Cell-Mediated Immunity
B. Ways That Cell-Mediated Immunity Help to Defend
the Body
17
D. Active and Passive Immunotherapy to Stimulate
Cell-Mediated Immunity against Tumors
III. IMMUNODEFICIENCY
A. Primary Immunodeficiency
B. Secondary Immunodeficiency
IV. HYPERSENSITIVITIES
A. Immediate Hypersensitivities
B. Delayed Hypersensitivities (Type IV)
C. Superantigens
Learning methods:
1. Lectures and small group discussion
2. Seminars
3. Practical classes
4. Self directed learning
Methods of assessment:
1. Written exam to assess knowledge, understanding and intellectual skills
1. Oral exam to assess the ability to identify and apply immunological
knowledge in a comprehensive oral way.
2. Practical exam assess practical and intellectual skills
Weighing of Assessments:
End-semester MCQ &Written Exam 150 marks
End-semester Oral Examination……………. 30 marks
End-semester Practical Examination 20 marks
Total ……………. 200 marks
List of references
Course notes: Medial microbiology and Immunology Department books
Essential books:
Lecture Notes: Immunology (Todd and Spickett) Recommended Books
Medical Immunology (Parslow, Stites, Terr & Imoboden)
18
Immunobiology (Janeway, Travers, Walport, Shlomchik)
Medical Microbiology & immunology (Levinson & Jawetz)
Pharmacology course specification University: Ain Shams University Faculty: of Medicine
Course specifications
Program on which the course is given: Master degree in Medical Biochemistry
and Molecular Biology.
Major or minor element of programs: Major
Department offering the program: Medical Biochemistry and Molecular Biology
Department.
Department offering the course: Pharmacology Department.
Academic Level: Master – 1st semester
Date of specification approval: …………………………..
A- Basic Information
Title: pharmacology course Code: BM6001(b)
Credit Hours: 4hour Lecture: /week Total:
Coordinator
Pharmacology Department.
B - Professional Information
1- Course Aims:
The aim of this course is to provide students with an understanding of the
principles of pharmacology related to dosing, pharmacokinetics, biotransformation,
mechanisms of action, side effects, drug interactions, and compliance issues,
2- Intended Learning Outcomes (ILOs) from the Course:
a- Knowledge and understanding
By the end of the course the candidate will be able to:
a1) Discuss the pharmacokinetic, pharmacodynamic and pharmaco-
therapeutic properties of drugs.
a2) Discuss the adverse and toxic effects of drugs, and their management.
a3)Give an account on limitations to the use of drugs such as
contraindications and drug interactions.
a4) Define clinically relevant age, sex and genetic related variations that
affect response to drugs.
a5) Define the principles, the indications, the relative advantages and
disadvantages of various pharmacotherapy modalities.
19
A6) Recognize the rational and general guidelines of the use of drugs in the
proper dose in special population such as pediatrics, geriatrics, pregnancy and
lactation and in cases of liver and kidney impairment.
b- Intellectual skills
By the end of the course the candidate will be able to:
b1) Calculate accurately drug’s dosage, bioavailability, plasma half life and
volume of distribution in different patient populations.
b2) Document drug adverse reactions.
b3) Observe, record and analyze the effect of drugs on biological tissues
c- Professional skills
By the end of the course the candidate will be able to:
c1) Think independently, evaluate and reflect, set tasks and select appropriate and
reasoned approaches to solve problems;
c2) Use knowledge and understanding of the pharmacological sciences to
formulate and apply the principles of scientific inquiry to address pharmacology-
related problems;
c3) Apply the knowledge and understanding of the pharmacological sciences to
plan and undertake hypothesis-driven pharmacological research.
c4) Demonstrate confidence and competency in understanding, analysing and
interpreting pharmacological data
d- General and transferable skills
By the end of the course the candidate will be able to:
D1 - Understand the importance of life-long self-learning and show a strong
commitment to it.
D2 - Use current I.T. for appropriate drug database to reach information about a
specific medication.
D3- Respect ethics related to drug prescription and use especially to drugs liable to
produce abuse.
3- Course content:
Topics No of hours
(1) General pharmacology: L C/P SDL
20
Evaluation of new drugs
Pharmacokinetics
Biotransformation
Pharmacodynamics
Adverse Drug Interaction
Pharmacogenetic disorders
Drug Allergy
Drug interactions
(2) Pharmacology of Blood
Drug therapy of thrombosis
Anticoagulants
Antiplatelet drugs ( Anti-Thrombotics )
Fibrinolytics ( Thrombolytics )
Drugs used in bleeding disorders
Vitamen K
Fibrinolytic Inhibitors ( Antiplasmin )
Drug therapy of Anemia
Drug-induced blood disorders
Drug therapy of hyperlipidemia
Management of Hyperlipidemias
(3)- Renal Pharmacology
Diuretics
Drugs and Potassium Homeostasis
Disturbances in K+ serum level
Drugs and Acid-Base Balance
21
Treatment of renal stones
(4)-Endocrine Pharmacology
Insulin & oral antidiabetic drugs
Drugs Affecting Bone calcium Homeostasis
Hypothalamic & pituitary hormones
Thyroid hormones and antithyroid drugs
Anti thyroid drugs
Corticosteroids
Sex hormones
(5)- Chemotherapy
Antibacterial Chemotherapy
Cytotoxic drugs
L: Lectures and SDL: Self directed learning
4 - Student Assessment Methods
4.1 written exam to assess knowledge, skills
4.2 Oral exam to assess General and transferable skills
4.3 Practical exam to assess practical and intellectual skills
Weighing of assessment
End-semester MCQ &Written Exam 150 marks
End-semester Oral Examination……………. 30 marks
End-semester Practical Examination 20 marks
Total ……………. 200 marks
5 -- List of References
5.1- Course Notes (paper and / or electronic): Deparment Book
5.2- Essential Books (Text Books)
5.3- Recommended Books
Principles of Clinical Pharmacology
5.4- Periodicals, Web Sites, etc
22
http://www.centerwatch.com/drug-information/fda-approvals/drug-
areas.aspx?AreaID=8
http://www.medilexicon.com/drugsearch.php?a=19
http://www.chilanti.com/olbooks/medbooks/Cochrane_Musculoskeletal_Group.ht
m
Medical Physiology Course Specification: University: Ain Shams University Faculty: of Medicine
Course specifications
Program on which the course is given: Master degree in Medical Biochemistry
and Molecular Biology.
Major or minor element of programs: Major
Department offering the program: Medical Biochemistry and Molecular Biology
Department.
Department offering the course: Medical Physiology Department.
Academic Level: Master – 1st semester
Date of specification approval: …………………………..
A- Basic Information
Title: Medical Physiology course Code: BM6001(c)
Credit Hours: 4 hour Lecture: /week Total:
Coordinator
Medical Physiology Department.
B - Professional Information
1- Course Aims:
a- To understand functions of different body systems and organs.
b- To integrate regulatory mechanisms of different body functions in
health & disease states
2- Intended Learning Outcomes (ILOs) from the Course:
a- Knowledge and understanding
By the end of the course the candidate will be able to:
a1-Recognize the functions of different body systems and the
mechanisms involved in its regulation
23
a2-Describe how different body functions are integrated to maintain
homeostasis
a3-Interprete & explain disturbed body functions in different diseases
b- Intellectual skills
By the end of the course the candidate will be able to:
b1- Analyze the given information.
b2- Think and expect the outcome of disturbed function
b3- Solve problems through case study and choose the
best from multiple .
b4- Hypothesize and experiment physiological principles
c- Professional skills
By the end of the course the candidate will be able to:
c1- Carry out all experiments in practical physiology classes
Blood tests .e.g. Blood groups , E.S.R.. Haemostatic function
(bleeding time,clotting time),hemoglobin, hematocrite value and
capillary fragility.
metabolic rate – oxygen consumpt
perform isolated perfused organ study, nerve & muscle preparation.
C4-Use different equipments in physiology department for scientific rsearch.
d- General and transferable skills
By the end of the course the candidate will be able to:
d1- communicate with medical students in practical classes and small group
discussions.
d2-communicate with staff members in physiology department and other
departments.
d3- present seminars in different issues in physiology in scientific meetings &
medical conferences.
3- Course contents
Topics No. of hours
L P SDL
24
(I) General & cellular Basis of Medical Physiology:
1. Homeostasis and feedback mechanisms.
2. Cell membrane (structure, characteristics
& channels).
3. Transport across cell membrane.
4. Membrane potentials (resting membrane
potential and action potentials).
5. Second messenger pathways.
6. Cellular organelles and their functions.
7. Cybernetics in physiology.
8. Receptors in physiology.
9. Body fluids and water balance.
10
٭
(II) Physiology of Nerve and Muscle:
1. Types of muscles (skeletal, cardiac & smooth
muscles).
2. Electrical activity of nerve & muscle (resting
membrane potential and action potential).
3. Neuromuscular junctions and excitation
contraction coupling.
4. Conduction of nerve impulse.
5. Energy sources & metabolism of skeletal
muscle.
6. Physiology of smooth muscles.
7. Assessment of muscle and nerve functions.
8. Effects of nerve lesions (degeneration &
regeneration).
٭ 10
(III) Physiology Of Blood:
1. Physiology of red blood cells.
2. Normal and abnormal haemoglobins.
3. Haematopoiesis, anaemias and polycythemia.
4. Blood groups and blood transfusion.
5. Physiology of leucocytes.
6. Immune mechanisms, allergy , anaphylaxis &
autoimmune disorders.
7. Platelet physiology .
8. Haemostasis, coagulation, fibrinolysis and
anticlotting mechanisms. Common coagulation
disorders.
9. Hormones affecting the different components of
10
25
blood.
10. Plama proteins: types, origins, concentrations
and functions- hypoproteinemia.
11. Functions of spleen and reticulo-endothelial
system.
12. Physiology of tissue macrophage system.
13. Physiology of lymph.
(IV) Energy & General Metabolism:
1. Thermoregulation and fever hypo-&
hyperthermia.
2. Energy balance, control of food intake,
obesity, under & malnutrition, leptin.
3. Metabolic rate and BMR
4. Respiratory Quotient(R.Q)
5
(V) Endocrine Physiology:
1. General concepts in endocrine physiology.
2. Mechanism of action of hormones.
3. Control of endocrine functions (role of
hypothalamus,hypothalamic–pituitary
relationship).
4. Physiology of pituitary gland and its disorders.
5. Physiology of thyroid gland its disorders.
6. Physiology of adrenal cortex and its disorders.
7. Calcium homeostasis and Tetany.
8. Glucose homeostasis and pancreas & diabetes
mellitus.
9. Physiology of growth–Insulin like growth
factors.
10. Physiology of puberty.
11. Magnesium homeostasis.
12. Phosphorus homeostasis and physiology of
bone.
13. Ectopic hormones.
14. Prostaglandins and their physiologyical
significance.
10
26
VI) Physiology of Kidney and Body Fluids:
1. Functional structure.
2. Kidney functions in the regulation of body
fluids. Role of ADH in the regulation of total
body water.
3. Renal circulation and renal blood flow.
4. Glomerular filteration and autoregulation.
5. Tubular function reabsorption and secretion.
6. Plasma clearance, renal handling of Na,
glucose. Bicarbonate & NH3.
7. Regulation of excretion Na, CI & K.
8. Acid–base balance and its disturbances.
Anion gap.
9. Concentration, dilution & acidification of
urine.
Micturition and its disorders.
10
Practical Course For M.Sc. Physiology
(1) Smooth Muscle and Autonomic Receptors:
(2) Blood Physiology:
Determination of hemoglobin content.
Determination of packed cell volume
(Haematocrit value)- Anemia – Polycythemia –
Blood indices.
Erythrocyte sedimentation rate (ESR).
Osmotic fragility test.
Evaluation of hemostatic function of blood:
a. Determination of the bleeding time.
b. Determination of whole blood clotting time.
c. Determination of prothrombin time (PT).
d.Determination of activated partial
thromboplastin time (APTT). - (Purpura–
Haemophilia–Hypoprothrombinemia-
Hypofibrinogenemia – Hypercoagulability
states).
Blood groups:
a. ABO.
12
L: Lecture, T: Tutorial, C/P: Clinical or Practical and SDL: Self directed learning
27
4 – Teaching and Learning Methods
4.1-Practical lessons
4.2-Discussion sessions
4.3-Research assignment
4.4-Self directed learning
4.5-E-learning
5- Student Assessment Methods
5.1 Written Exam. to assess:Knowledge & understanding and intellectual skills
5.2 Practical Exam to assess: Professional& practical skills
5.3 Oral Exam to assess|:General & transferable skills
Weighing of assessment:
End-semester MCQ &Written Exam 150 marks
End-semester Oral Examination……………. 30 marks
End-semester Practical Examination 20 marks
Total ……………. 200 marks
6 -- List of References
6.1- Course Notes: Lecturer notes
6.2- Essential Books (Text Books)
o Review of medical physiology By: William F. Ganong
o Text Book of medical physiology By: Guyton.
o BEST AND TAYLOR ’ s Physiological basis of Medical practice.
6.3- Recommended Books:
o Human physiology from cell to system By: Lauralee Sherwood.
6.4- Periodicals, Web Sites, … etc
o www. Pubmed.com.
o Ain Shams medical journal
o Am. J. of physiology.
o http:// mic2.shams.eg ( Faculty web site)
Course specifications of Practical Biochemistry University Ain Shams Faculty of Medicine Programme(s) on which the course is given: Master of Science in Medical
Biochemistry and Molecular Biology
Major or minor element of programmes: Major
Department offering the programme:Medical Biochemistry & Molec. Biology
Department offering the course: Medical Biochemistry and Molecular Biology
Academic Level: MSc., first semester
28
Date of specification approval:
A- Basic Information
Title: Master of Science in Medical Biochemistry and Molecular Biology
Code: BM6002
Credit Hours: 2 credit hours
Lecture: h Tutorial: Practical: h Total: h
Co-ordinator: Department of Medical Biochemistry and Molecular Biology B - Professional Information 1- Course Aims:
1- To provide the students with a solid background of practical biochemistry
concepts and skills and relate them to the theoretical biochemical information.
2- To equip the students with preliminary knowledge and skills necessary for
Biochemistry research
2- Intended Learning Outcomes (ILOs) from the Course:
a- Knowledge and understanding By the end of the course the candidate should be able to:
a1) Describe how to express the concentration of solution using SI units,
and how to change the concentration by dilution.
a2) Understand the steps of preparation of acids and bases.
a3) Describe the mechanism of buffering and important physiological
buffers.
a4) State the laws of spectrophotometry, compare qualitative to
quantitative assays, and compare direct to coupled enzyme assays.
b- Intellectual skills
By the end of the course the candidate will be able to:
b1- Integrate laboratory biochemical results with clinical data.
b2- Analyse and interpret the results of biochemical experiments.
c- Professional and Practical skills
By the end of the course the candidate should be able to:
c1-Demonstrate a professional attitude and good communication skills by effective
participation in cooperative problem solving, in small group exercises directed
towards understanding the biochemical and genetic bases of disease origins,
diagnoses and treatments
c2- Apply different methods for expression of concentration and calculation of the
dilution of solution.
29
c3- Demonstrate ability to prepare buffers and chose the proper buffer for each
medium.
c4- Use spectrophotometric assay methods to determine the concentration of proteins and enzymes.
C5- Follow proper method of disposal of biohazardous samples
(infectious, carcinogenic, etc.).
C6- Use the computer to retrieve and compare practical biochemistry data
d- General and transferable skills
By the end of the course the candidate will be able to:
d1 – Develop the skill of working in teams
d2 – Develop appropriate relationships with patient and family
d3- Use basic computing skills and internet to follow electronic lectures
d4- Communicate relevant information with teaching staff and colleagues
3- Course content:
PRACTICAL BIOCHEMISTRY L C/P SDL
Lab orientation and lab safety 2
Sampling procedures and tubes 2
Expression of concentration of solutions
Conversion to SI units
2
Changing concentration by dilution
2
Preparation of acids and bases
2
Diffusion through membranes:
-Dialysis
-Osmosis
-Osmotic behaviour of living cells
2
Water dissociation and pH
Acids and bases
Strong and weak acids
Ka and pKa of weak acids
2
Preparation of buffers
2
Spectrophotometry:
-Lambert’s law
6
30
-Beer’s law
-Qualitative spectrophotometric assays.
- Quantitative spectrophotometric assays.
- Construction and properties of a spectro-
photometer.
- Direct and coupled enzyme assay
Measurement of total serum proteins
Measurement of Blood glucose:
OGTT
Glycosylated Hb and fructosamine
2
Assessment of serum lipid profile 2
L: Lecture, T: Tutorial, C/P: Clinical or Practical and SDL: Self directed learning
4 - Student Assessment Methods
5.1- Class Discussions: to detect weak points and to emphasize important points
5.2- Practical exam: to assess professional and practical skills.
Weighing of Assessments: (1) End first semester practical exam 100 marks
Total ……………. 100 marks
Any formative only assessments: Non
5 -- List of References
5.1- Course Notes (paper and / or electronic)
Practical Biochemistry Department book provided by the staff of Medical
Biochemistry and Molecular Biology
………………………………………
…5.2- Essential Books (Text Books)
Experimental Biochemistry Theory and Exercises in Fundamental
Methods, Robert Switzer and Liam Garity, 3rd
edition
Analytical Biochemistry, David J Holme and Hazel Peck, 1998, Pearson
educ., Addison Wesley Longman limited.
Medical Biochemistry course specification University: Ain Shams University Faculty: of Medicine
31
Course specifications
Program on which the course is given: Master degree in Medical biochemistry
and Molecular Biology
Major or minor element of programs: Major
Department offering the program: Medical Biochemistry and Molecular Biology
Department
Department offering the course: Medical biochemistry and Molecular Biology
Department
Academic Level: Master – Second semester
Date of specification approval: …………………………..
A- Basic Information
Title: Medical biochemistry course. Code: BM6003
Credit Hours: 12 hour Lecture: /week Total:
Coordinator: Medical Biochemistry and Molecular Biology Department
a- Professional Information
1 – Overall Aims of Course
To provide postgraduate students with a basic understanding of the biological
processes in humans at a molecular level and to correlate any molecular defect or
abnormality to medical problems
To provide the postgraduate students with the opportunity to become competent
medical biochemists with the skills required to be a professional of medical
biochemistry laboratory.
To provide the environment necessary to develop skills in self-evaluation, self-
directed learning and critical appraisal enabling the medical biochemist to adapt to
the rapid progress of information and changes that will occur in the profession
throughout their careers.
2 – Intended Learning Outcomes of Course (ILOs)
b- Knowledge and Understanding: By the end of the course, students
should be able to:
a1-Discuss normal biochemical pathways and the etiology and pathogenesis of the
biochemical disorders of disease
a2- Describe the structure function relationship of some important proteins:
hemoglobin, myoglobin, skeletal muscles, collagen, and immunoglobulins.
32
a3- Explain the methods of classification and regulation of enzymes as well as
kinetics of enzymes and coenzymes.
a4- Describe the structure of biological membranes and classify the different
mechanisms of signal transduction across membranes
a5- Describe the metabolic pathways of carbohydrates, lipids, and proteins, their
energetics, their sites, and the ways of their regulation.
A6- Define the possible metabolic errors arising from deficiency of certain
metabolic enzyme
A7- Describe the components of mitochondrial ETC and their inhibitors.
A8- Point out sources and fate of ammonia in human body and the causes of
ammonia intoxication. A9- Define which nitrogenous compounds are derived from each amino acid and
describe their synthesis, degradation and functions.
a10- Explain the different patterns of fuel metabolism in different organs, during
the fast and fed states
a11- Describe the composition of blood and explain the mechanism of blood
clotting, anticoagulation and fibrinolysis.
a12- Summarize the functions and deficiency diseases of vitamins and minerals.
a13-Summarize the various mechanisms of xenobiotic metabolism
a14- Identify cell adhesion molecules
b-Intellectual Skills: By the end of the course, students should be able to:
b1- Integrate basic biochemical facts with clinical diseases.
B2- Identify electrophoretic bands, interpret disease-associated changes in plasma
proteins and diagnose sickle cell trait and sickle cell anemia
B3- Solve any subject-related problems provided by staff
B4- analyze laboratory data using statistical rules.
c- Professional and Practical Skills: By the end of the course, students
should be able to:
C1- Demonstrate ability to choose the type of protein assay in a given biologic
fluid.
C2- Separate proteins by molecular sieving, and by ion exchange or thin layer
chromatography
C3- Perform different types of assays as ELISA, immunodiffusion.
C4- Identify and interpret electrophoresis results of different types.
C5- Apply methods to prevent contamination of the lab and equipments.
C6- Follow proper method of disposal of biohazardous samples (infectious,
carcinogenic, etc.).
C7- Perform urine and stone analysis.
33
d- General and Transferable Skills: By the end of the course, students
should be able to:
d1- Work in a team in the lab and cooperate with their colleagues and staff.
d2- Use basic computing skills and internet to fulfill problem-based learning
d3- Communicate relevant information with teaching staff and colleagues
3- Contents
Topic L C/P SDL
Water, acids, bases and buffers
Chemistry of amino acids and proteins
Protein structure-function relationship:
-Hemoglobin and Myoglobin
-Immunoglobulins
-Collagin and elastin
-Plasma Proteins
-Muscle proteins
Enzymes
Carbohydrate chemistry and metabolism
Bioenergetics and Biological oxidation
Lipid chemistry and metabolism metabolism
O2 toxicity and free radical injury
Metabolism of ethanol
Protein Metabolism:
General protein metabolism
Individual amino acid metabolism
Integration of Metabolism
Starvation
Diabetes mellitus
Biological membranes
Biosignalling
Apoptosis
Cell adhesion molecules
Metabolism of Nucleotides
Iron and Heme Metabolism
Nutrition-malnutrition and obesity
Vitamins and Mineral Metabolism
Metabolism of Zenobiotics
34
Blood composition,
Blood coagulation and fibrinolysis
PRACTICAL BIOCHEMISTRY
Urine analysis
Stone analysis
Protein purification:
- Molecular sieving
- Ion exchange chromatography
- Affinity chromatography
- Thin layer chromatography
- How to check protein purity
Assay of proteins in biologic fluids:
-Simple colorimetric assay
-Turbidimetric assay
-ELISA
-RIA
-Immunohistochemistry
-Immunodiffusion
Electrophoresis:
- General principals
- Cellulose acetate membrane electophoresis
- Polyacrylamide gel electroph.
-DNA and RNA electrophoresis using agarose gel
- Gel photography
Blood coagulation testing
4– Teaching and Learning Methods
4.1- Lectures: using data show and overhead projectors
4.2- Practical Training
4.3- Discussion sessions: as journal clubs and seminars
4.4- Collection of information using the internet
5- Student Assessment Methods
35
5.1- Class Discussions: to detect weak points and to emphasize important points
5.2- Quizes at the end of each subject to assess understanding and weak points
5.3- Oral exam: to assess knowledge, understanding and information presentation
ability
5.4- Practical exam: to assess practical skills aquired by students
5.5- Written end-year exam to assess knowledge and understanding.
Weighing of Assessments: (1) Periodic quizzes 70 marks
(2) Written exam 200 marks
(4) Practical exam (Cases and Skills) 240 marks
(5) Oral exam 090 marks
Total ……………. 600 marks
Any formative only assessments: Non
6 -- List of References
6.1- Course Notes (paper and / or electronic)
Lectures notes and Practical Biochemistry book provided by the staff of Medical
Biochemistry and Molecular Biology Department.
6.2- Essential Books (Text Books)
Lippincott's Illustrated Reviews: Biochemistry, Champe PC, 4th
edition.
Lippincott Williams & Wilkins Pub., 2009.
Harper's Illustrated Biochemistry, Robert K. Murray RK, Granner DK, Mayes PA
and Rodwell VW 27th edition, McGraw-Hill Medical Pub., 2006.
Lehninger Principles of Biochemistry, Nelson DL and Cox MM, 5th
edition,
Freeman Pub, 2009.
Biochemistry lecture notebook, Berg JM, Tymoczko JL and Stryer L, 6th
edition,
Freeman Pub., 2006.
6.3- Recommended Books
Biochemistry: A Case Oriented Approach, Montgomery R et al, 6th
edition, Mosby,
1996.
USMLE Road Map Biochemistry, Macdonald R, 1st edition. McGraw-Hill Medical
Pub., 2007.
Textbook of Biochemistry with Clinical Correlations, Devlin TM, 6th
edition,
Wiley-Liss, Inc. Pub., 2005.
36
6.4- Periodicals, Web Sites, … etc
http://mic2.shams.edu.eg/moodle
www.medicaleducationonline.org
www.eul.edu.eg
www.wilkpedia.com
www.encyclopedia.com
Molecular Biology Course specifications: University Ain Shams Faculty of Medicine Programme(s) on which the course is given: Master of Science in Medical
Biochemistry and Molecular Biology
Major or minor element of programmes: Major
Department offering the programme: Medical Biochemistry and Molecular
Biology
Department offering the course: Medical Biochemistry and Molecular Biology
Academic Level: MSc. 1st part
Date of specification approval:
A- Basic Information
Title: Master of Science in Medical Biochemistry and Molecular Biology
Code: BM6004
Credit Hours: 6 credit hours
Lecture: Tutorial: Practical: Total:
Co-ordinator: Department of Medical Biochemistry and Molecular Biology B - Professional Information
1- Course Aims:
1- To provide the postgraduate students with the opportunity to become competent
medical biochemists with the skills required to be an effective consultant for
clinical colleagues and a professional of medical biochemistry laboratory.
2- To equipping the students with the specialized knowledge and skills necessary
for future research.
2- Intended Learning Outcomes (ILOs) from the Course:
37
a- Knowledge and understanding
By the end of the course the candidate will be able to:
a1) Understand the structure, function and organization of human genomes
a2) Describe the main principles of methods for preparation and extraction
of DNA and RNA.
a3) Understand the main principles of methods for DNA amplification
(PCR, RT-PCR, Real-time PCR, etc.)
a4) Identify the main principles of methods for DNA sequencing
a5) Describe the main principles of DNA and RNA blotting
a6) Understand the concepts of recombinant DNA technology
a7) Understand the applications of molecular biology techniques in the
diagnosis, taxonomy, species and strain differention of
microorganisms.
.a8) Understand the applications of molecular biology techniques in genetic
testing, in paternity testing, studying drug resistance, and vaccine and
drug development.
a9) Point out the principle of microarrays
b- Intellectual skills
By the end of the course the candidate will be able to:
b1- Integrate basic molecular biology facts with clinical data.
b2- Identify the appropriate experimental technique required to diagnose a
genetic disease.
b3- Analyse and interpret the results of molecular biology techniques.
c- Professional and Practical skills
By the end of the course the candidate will be able to:
c1- Incorporate new molecular biology knowledge and tools into research
projects
c2- Use the computer to retrieve and compare molecular biology data
c3- Solve any subject-related problems provided by staff
c4- Apply methods to prevent contamination of the lab and equipments.
c5- Follow proper method of disposal of biohazardous samples
(infectious, carcinogenic, etc.).
c6- Demonstrate the ability to extract DNA and RNA
c7- Interpret the results of PCR and RT-PCR, blotting teckniques, and DNA
finger printing
38
d- General and transferable skills
By the end of the course the candidate will be able to:
d1 – develop the skill of working in teams
d2 – develop appropriate relationships with patient and family
d3- Use basic computing skills and internet to follow electronic lectures
d4- Communicate relevant information with teaching staff and colleagues
d5) Search gene and protein Database.
d6) Use molecular biology software.
3- Course content:
Basic principles in molecular biology L (1h) P SDL
1- Nucleic acid structure and organization 6
2- Cell cycle, DNA replication and repair 6
3- RNA transcription and processing 6
4- Regulation of gene expression 4
5-The Genetic code, mutation and protein
synthesis
6
6- Cloning:
Gene (DNA) cloning
Reproductive cloning
Therapeutic cloning
6
7- Techniques of genetic analysis
-Extraction of DNA & RNA
- PCR & RT-PCR
- DNA electrophoresis
- Blotting techniques
- RFLP
- Microarray
8 10
8- Genetic variation &
DNA finger printing
4
9- Molecular biology of cancer
- Oncogenes,
- Tumor suppressor genes,
- Apoptosis
- Telomerase
- invasion and metastasis
- Angiogenesis
4
39
10- Transgenesis &
Gene Therapy
6
11- Stem cells
4
13-Ethical, Legal, and Social implications of
genetic knowledge
4
14- Personalized Medicine
2
L: Lecture, T: Tutorial, C/P: Clinical or Practical and SDL: Self directed
learning
4 - Student Assessment Methods
5.1- Class Discussions: to detect weak points and to emphasize important points
5.2- Quizes at the end of each subject to assess understanding and weak points
presentation ability
5.3- Written final exam to assess knowledge and understanding.
Weighing of Assessments: (1) Written end-year exam 150 marks
Total ……………. 150 marks
Any formative only assessments: Quizes at the end of each
6 -- List of References
6.1- Course Notes (paper and / or electronic)
Lectures notes and Practical Biochemistry book provided by the staff of Medical
Biochemistry and Molecular Biology Department.
6.2- Essential Books (Text Books)
Biochemistry: A Case Oriented Approach, Montgomery R et al, 6th
edition, Mosby,
1996.
USMLE Road Map Biochemistry, Macdonald R, 1st edition. McGraw-Hill Medical
Pub., 2007.
Textbook of Biochemistry with Clinical Correlations, Devlin TM, 6th
edition,
Wiley-Liss, Inc. Pub., 2005.
40
6.3- Recommended Books
Lippincott's Illustrated Reviews: Biochemistry, Champe PC, 4th
edition.
Lippincott Williams & Wilkins Pub., 2009.
Harper's Illustrated Biochemistry, Robert K. Murray RK, Granner DK, Mayes PA
and Rodwell VW 27th edition, McGraw-Hill Medical Pub., 2006.
Lehninger Principles of Biochemistry, Nelson DL and Cox MM, 5th
edition,
Freeman Pub, 2009.
Biochemistry lecture notebook, Berg JM, Tymoczko JL and Stryer L, 6th
edition,
Freeman Pub., 2006.
5.4- Periodicals, Web Sites, etc
http://www.web-books.com/MoBio/
http://www.coe.uncc.edu/~hhilger/EB_I_F_06/web_links_on_basics_of_mo
lecular_biology.htm
http://plato.acadiau.ca/courses/biol/Microbiology/Basics.htm
http://www.wiley.com/legacy/college/boyer/0470003790/animations/cell_st
ructure/cell_structure.htm
http://www.cellsalive.com/cells/3dcell.htm
http://www.johnkyrk.com/DNAanatomy.html
http://www.johnkyrk.com/DNAreplication.html
http://www.johnkyrk.com/DNAtranscription.html
http://www.johnkyrk.com/DNAtranslation.html
http://www.rothamsted.ac.uk/notebook/courses/guide/
http://www.bio.com/protocolstools/protocol.jhtml?id=p1242
http://users.ugent.be/~avierstr/principles/pcr.html
http://depts.washington.edu/genetics/courses/genet371b-
aut99/PCR_contents.html [animation]
http://www.sumanasinc.com/webcontent/anisamples/molecularbiology/pcr.h
tml [animation]
http://www.sumanasinc.com/webcontent/anisamples/molecularbiology/mole
cularbiology.html (animated techniques
Course specifications of Applied Biochemistry University Ain Shams Faculty of Medicine Programme(s) on which the course is given: Master of Science in Medical
Biochemistry and Molecular Biology
Major or minor element of programmes: Major
41
Department offering the programme: Medical Biochemistry and Molecular
Biology
Department offering the course: Medical Biochemistry and Molecular Biology
Academic year: MSc. Second Part
Date of specification approval:
A- Basic Information
Title: Master of Science in Medical Biochemistry and Molecular Biology
Code: BM6005
Credit Hours: 2 credit hours
Lecture: h Tutorial: Practical: h Total: h
Co-ordinator: Department of Medical Biochemistry and Molecular Biology B - Professional Information 1- Course Aims:
To provide the postgraduate students with the opportunity to apply biochemical
knowledge and molecular biology information in problem solving and case
interpretation
Equipping of the students with the specialized knowledge and skills necessary to
be a professional of medical biochemistry laboratory.
2- Intended Learning Outcomes (ILOs) from the Course:
a- Knowledge and understanding By the end of the course the candidate should be able to:
a1) Point out the various metabolic and genetic diseases related to each
course topic.
a2) Understand how to use biochemical and molecular biology knowledge
in the diagnosis and interpretation of clinical picture of patients.
b- Intellectual skills
By the end of the course the candidate will be able to:
b1- Integrate basic biochemical and molecular biology information with
clinical disease
b2- Analyse and interpret laboratory and clinical data to reach a diagnosis
and predict the course of a disease.
c- Professional and Practical skills
42
By the end of the course the candidate should be able to:
c1-Demonstrate a professional attitude and good communication skills by effective
participation in cooperative problem solving, in small group exercises directed
towards understanding the biochemical and genetic bases of disease origins,
diagnoses and treatments
c2- Apply different methods for expression of concentration and calculation of the
dilution of solution.
c3- Demonstrate ability to prepare buffers and chose the proper buffer for each
medium.
C4- Demonstrate ability to interpret different molecular biology techniques in the
diagnosis of hereditary diseases
C5- Identify and interpret electrophoresis results of different types.
c-6 Interpret the results of PCR and RT-PCR and DNA finger printing
d- General and transferable skills
By the end of the course the candidate will be able to:
d1 – Develop the skill of working in teams
d2 – Develop appropriate relationships with his colleagues and staff members.
d3- Use basic computing skills and internet to follow electronic lectures
d4- Communicate relevant information with teaching staff and colleagues
Course contents:
L P
Problems related to:
Preparation of solutions
Changing concentration by dilution
Preparation of acids, bases, and buffers
Osmosis, dialysis, ..
Cases and problems related to:
Protein folding and misfolding
e.g. Alzheimer D
e.g. Prion disease
Cases and problems related to:
-Hemoglobinopathies
-Collagin and elastin
Cases and Problems related to:
Enzyme kinetics
Enzyme inhibitors
Enzymes in clinical diagnosis
43
Cases and problems related to:
Carbohydrate metabolism
Cases and problems related to:
Bioenergetics and Biological oxidation
Cases and problems related to:
Lipid metabolism metabolism
Cases and problems related to:
Metabolism of ethanol
Cases and problems related to:
Protein Metabolism:
Cases and problems related to:
Integration of Metabolism
Starvation
Metabolism of special organs
Cases and problems related to:
Diabetes mellitus
Cases and problems related to:
Biological membranes
Biosignalling
Cell adhesion molecules
Cases and problems related to:
Defective nucleotide metabolism:
e.g. Gout
Cases and problems related to:
Hyperbilirubinemia
Porphyria
Cases and problems related to:
Malnutrition
Cases and problems related to:
Nutrition
Obesity
Vitamin deficiency
Cases and problems related to:
Defective mineral metabolism:
e.g. Hypocalcemia and hypercalcemia
e.g.Wilson D
e.g. Congenital and aquired iron overload
44
Cases of Blood diseases
hemophilia
Hypercoagulable states
Cases and problems related to:
DNA damage and repair
Posttranscriptional modification
Genetic code and mutations
Techniques of genetic testing
DNA finger printing
4 - Student Assessment Methods
5.1- Class Discussions: to detect weak points and to emphasize important points
5.2- Written exam: to assess knowledge and understanding.
Weighing of Assessments: (1) End sec part written exam 100 marks
Total ……………. 100 marks
Any formative only assessments: Non
6 -- List of References
6.1- Course Notes (paper and / or electronic)
Lectures notes and Practical Biochemistry book provided by the staff of Medical
Biochemistry and Molecular Biology Department.
6.2- Essential Books (Text Books)
Biochemistry: A Case Oriented Approach, Montgomery R et al, 6th
edition, Mosby,
1996.
USMLE Road Map Biochemistry, Macdonald R, 1st edition. McGraw-Hill Medical
Pub., 2007.
Textbook of Biochemistry with Clinical Correlations, Devlin TM, 6th
edition,
Wiley-Liss, Inc. Pub., 2005.
6.3- Recommended Books
45
Lippincott's Illustrated Reviews: Biochemistry, Champe PC, 4th
edition.
Lippincott Williams & Wilkins Pub., 2009.
Harper's Illustrated Biochemistry, Robert K. Murray RK, Granner DK, Mayes PA
and Rodwell VW 27th edition, McGraw-Hill Medical Pub., 2006.
Lehninger Principles of Biochemistry, Nelson DL and Cox MM, 5th
edition,
Freeman Pub, 2009.
Biochemistry lecture notebook, Berg JM, Tymoczko JL and Stryer L, 6th
edition,
Freeman Pub., 2006.
6.4- Periodicals, Web Sites, … etc
http://mic2.shams.edu.eg/moodle
www.medicaleducationonline.org
www.eul.edu.eg
www.wilkpedia.com
www.encyclopedia.com
Medical statistics course specification
University: Ain Shams University Faculty: of Medicine
Course specifications
Program on which the course is given: MSc in Medical Biochemistry and
Molecular Biology
Major or minor element of programs: Major
Department offering the program: Medical Biochemistry and Molecular Biology
Department offering the course: Community, Environmental and Occupational
Medicine
Academic Level: M.Sc. (elective course)
Date of specification approval: …………………………..
A- Basic Information
Title: Medical statistics course Code: E6009
Credit Hours: 1 hour
46
Coordinator
Community, Environmental and Occupational Medicine Department
B - Professional Information
1- Course Aim:
To enable the M.Sc. candidate to plan, conduct, analyze and interpret the results of
a research in his specific field. This course unit introduces the application of
statistical ideas and methodology to medical research.
2- Intended Learning Outcomes (ILOs) from the Course:
a- Knowledge and understanding
By the end of the course the candidate will be able to:
a1 - Define medical statistics and identify uses and importance of medical
statistics in medical research
a2 – Define:
Types of variables.
Descriptive statistics.
Presentation and summarization of data.
Measures of central tendency and scatter.
Principles of probability and probability distributions.
Concepts of inferential statistics: confidence interval and hypothesis testing.
Different tests of statistical significance.
Difference between parametric and nonparametric tests of significance.
Correlation and regression
Concept of statistical modeling using multivariable and multivariate
statistical methods.
Combining evidence from different studies and meta-analysis
Importance and methods of sampling and how to determine the suitable
sample size.
Different types of research methodology:
Observational and intervention studies and the different
statistical issues related to the design, conduct, analysis and
interpretation of the results of each study type.
Ethical aspects of medical research including those specifically applied to
clinical trials.
b- Intellectual skills
By the end of the course the candidate will be able to:
47
b1 - Interpret correctly the results of statistical analyses and critically
evaluate the use of statistics in the medical literature.
b2 - Integrate and evaluate information from a variety of sources.
c- Professional skills
By the end of the course the candidate will be able to:
c1- Select appropriate study designs to address questions of medical
relevance
c2- Select and apply appropriate statistical methods for analyzing data
typically encountered in medical applications.
c3- Use selected software packages for statistical analysis and data
management.
d- General and transferable skills
By the end of the course the candidate will be able to:
d1 - Work effectively in a group from different backgrounds.
d2 - Respects the role of staff and co-staff members regardless of degree or
occupation.
d3 - Communicate effectively with professional statisticians and the wider
medical community, including the ability to present results of
statistical analyses through written and oral presentations
d4 - Use of computer data bases and other computer skills.
d5 - Handle data appropriately and analyze them through: decision
processes, objective criteria, problem definition, project design and
evaluation, risk management, teamwork and coordination.
d6 - Learn independently with open-mindedness and critical enquiry.
3- Course content:
Topics
T C/P
Introduction to medical statistics and its uses
1
Types of variables and Descriptive statistics
1
Graphic presentation of data
1
Introduction to probability theory and rules
1
Sample and population: sampling distribution of mean and 1
48
proportion
Confidence interval of a mean and a proportion
1
Confidence interval of a difference between two mean /proportion
1
Testing a hypothesis about population mean/proportion
1
Testing a hypothesis about the difference between two
means/proportion
1
Comparing between more than two means-Introduction to
factorial analysis
1
Cross-tabulation and introduction to categorical data analysis
1
Simple correlation and simple regression
1
Introduction to multivariable and multivariate analysis
1
Study designs: observational studies
1
Study designs: Intervention studies: clinical trials
1
Study designs: Experimental animal studies
1
Study designs: Bias and Confounding 1
Ethical issues in medical research
1
Sample size estimation for continuous and binary outcome
measures.
1
Meta-analysis and publication bias.
1
T: Tutorial and C/P: Clinical or Practical and SDL: Self directed learning
4 - Student Assessment Methods
4-1 Written exam to assess knowledge and understanding and will
concentrate on problem solving questions
4-2 Weighing of assessment
Written exam 50
Total 50
49
5 - List of References
5.1- Course Notes (paper and / or electronic)
Student Notes on Medical Statistics and Research Methods. Prof. Mohsen
Abdel Hamid and Dr Moustafa El Houssinie. Department of Community,
Environmental and Occupational Medicine.
5.2- Essential Books (Text Books)
Statistics in Clinical Practice. avid Coggon. BMJ Books. 2nd
edition 2003
5.3- Recommended Books
Handbook of Epidemiology. Springer 2005
5.4- Periodicals, Web Sites, etc
www.brettscaife.net/statistics/introstat/
onlinestatbook.com/rvls/
www. Epidemiolog.net
http://www.shef.ac.uk/scharr/spss/
Bioinformatics Elective Course Specifications
University: Ain Shams University Faculty: of Medicine
Program on which the course is given: Master degree in Medical biochemistry
and Molecular Biology
Major or minor element of programs: Major
Department offering the program: Medical Biochemistry and Molecular Biology
Department
Department offering the course: Medical biochemistry and Molecular Biology
Department
Academic Level: Master – Second part
Date of specification approval: …………………………..
A- Basic Information
Title: Medical biochemistry and Molecular Biology course. Code: E6018
Credit Hours: 1 Lectures:8
Tutorials :4 Practical:10 Total: 22 hours
Coordinator: Medical Biochemistry and Molecular Biology Department
B- Professional Information
1 – Overall Aims of Course
50
Bioinformatics has been defined as the science of examining the
structure and function of genes and proteins through the use of
computational analysis, statistics, and pattern recognition. The field of
bioinformatics changes so rapidly that it is nearly impossible to keep up
with all the different areas of progress. A Bioinformatics postgraduate
course mainly aims at teaching students current state-of-the-art
bioinformatics status. There should be a solid understanding of the scope
of bioinformatics. It is also necessary to become aware of the tools and
techniques used in research and in applications. It is therefore necessary
to learn how to access new information and how to assimilate it into the
whole, in order to continue to learn beyond the limits of this course.
2 – Intended Learning Outcomes of Course (ILOs)
a- Knowledge and Understanding:
By the end of the course, students should be able to
a1- Understand bioinformatics, the application of
computational methods to interpret the rapidly expanding
amount of biological information.
a2- Describe the range of applications of bioinformatics to
molecular biology, clinical medicine, pharmacology,
biotechnology, agriculture, forensic science, anthropology
and other disciplines.
a3- State the role of computers and computer science in the
investigations and applications of the data.
d- Intellectual Skills
By the end of the course, students will be able to
b1- Understand the language of both experimental biologist
and computing scientist, and can bridge the gap between
them.
b2- Understand how sequence-structure relationships will form
the bridge to protein structure
b3- Gain to think about solving some health problems through
bioinformatics.
e- Professional and Practical Skills
By the end of the course, students will be able to
c1- Gain access to the data through the world wide web and use
the right methods for their analysis.
51
c2- Retrieve information, and calculate with the data, and
extend these skills by self-directed 'field work' on the web.
f- General and Transferable Skills
By the end of the course, students will be able to
d1- Discuss among partners involved in the bioinformatics
problems (biologists, statisticians and computer
professionals).
d2- Use the Web and other resources for gene and protein
surveys.
52
3- Contents
T /P Lecture No. of
hours
Topic Week
1 1 What is Bioinformatics?
1. 1
1 1 DNA structure and flow of
genetic information
2. 1
1 1 Regulation of gene expression 3. 3
1 1 Protein structure 4. 4
2 2 1 Sequences:
Biological DNA and protein
sequences, the genetic code
Sequence tools
5. 5
2 2 Handling sequences in biological
databases
6. 6
2 1 3 Sequence comparison:
Identity, similarity, and
homology.
7. 5
1 2 3 Pairwise sequence alignment
8. 9
2 1 1 Multiple Sequence Alignment
9. 2
9
2 2 3 Microarray 10. 1
2
1 2 3 Final Exam 11.
53
4– Teaching and Learning Methods
4.1- Power point slide presentations.
4.2- Practical online training.
4.3- Students presentations.
4.4- Open discussions.
5- Student Assessment Methods
5.1 Genetic code, translation and mutation exercises to assess their
understanding to the basic molecular biology concepts.
5.2 Weblems to assess their ability of doing WWW surveys.
5.3 Constructing phylogenetic trees to assess their ability to use
different bioinformatics programs.
5.4 Student presentations to assess understanding the basics and
ability to transfer knowledgeable skills.
Assessment Schedule
Assessment 1: The flow of genetic information. Week 4
Assessment 2: Sequence analysis tools and comparison. Week 9
Assessment 3: Data bases and protein structure. Week 12
Weighing of Assessments
Class discussion participation 5%
Homework (exercises, reading assignments) 10%
Practical work 10%
Individual presentations 15%
Final-term Examination 60%
Oral Examination. 0%
Total 100%
Any formative only assessments
6- List of References
6.1- Course Notes
The power point presentations.
PDF handouts.
6.2- Essential Books (Text Books)
54
Introduction to Bioinformatics by Arthur M. Lesk (2005).
Papers and handouts relevant to presented topics will be
distributed as needed.
6.3- Recommended Books
Discovering Genomics, Proteomics, and Bioinformatics
by A. Malcolm Campbell, Laurie J. Heyer
Introduction to Bioinformatics: A Theoretical and
Practical Approach by Stephen A., Ph.D. Karwetz
(Editor), David D., Ph.D. Womble (Editor)
Bioinformatics For Dummies (For Dummies (Math &
Science))
by Jean-Michel Ph. D. Claverie, Cedric Ph.D. Notredame
Introduction to Protein Science: Architecture, Function,
and Genomics by Arthur M. Lesk
6.4- Periodicals, Web Sites, … etc
http://www.ncbi.nlm.nih.gov/
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM
http://www.ensembl.org/index.html
http://www.expasy.org/
http://www.bioinformatik.de
http://post.queensu.ca/~forsdyke/bioinfor.htm
http://www.techfak.uni-bielefeld.de/bcd/ForAll/Basics
http://www.dnaftb.org/dnaftb/
http://www.perl.com/pub/q/documentation
http://www.pdg.cnb.uam.es/cursos/FVi2001/GenomAna/GeneIdentif
ication/SearchContent/main.html
http://www.rcsb.org
http://scop.mrc-lmb.cam.ac.uk/scop/
http://www.genebee.msu.su/services/phtree_reduced.html
http://evolution.genetics.washington.edu/phylip/software.html
http://copland.udel.edu/~schmidtc/html/internet_links.html
7- Facilities Required for Teaching and Learning
PCs, Data show, whiteboard and markers, Printer and papers,
copying machine, and Internet connection
55
Your log book 1- Introduction
The aim of this book is to give you a guide to the expectations for each
item. It will be a guide for both you and your teachers to what you should be seeing
and doing.
It will give you a list of the important topics that you should think about and
should be covered in:
1. Clinical or practical sessions
or
2. Lectures
or
3. Self-directed learning (SDL)
For each item there is also a list of
1. Clinical conditions or Practical sessions to be seen or
attended (According to each degree)
2. Practical procedures to be seen and done
Remember
This document is only a guide. It is not an exhaustive list. It is not just a checklist
to score points. It is a guide to encourage you to read and learn more. This book is
for your benefit. It will form a record of your clinical training and experience.
2 - Supervisors
……………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………… 3–Tables for Training Records Requirements Candidates are required to fulfill 75% of the listed activities in order to be eligible
for the exam entry. The minimum number required for each activity = 75%. You
are free to attend more and record your extra attendance.
56
Weekly Department Plan Day
/time
Saturday Sunday Monday Tuesday Wednesday Thursday
Lectures 9-11 am 9-11 am
Practical
Sessions
9am-12pm
Seminars
11am -1 pm
Journal
Club
12-2 pm
Conferences attendance
(NB. Minimum number required is 2)
No
Da
te
Pla
ce
Topics Supervisor
signature
1
2
Thesis attendance
(NB. Minimum number required is 4)
No Date Place Name of the thesis Supervisor
signature
1
2
3
4
Journal club attendance
(NB. Minimum number required is 8)
No
Da
te
Pla
ce
Topics Supervisor
signature
1
57
2
3
4
5
6
7
8
Seminars attendance
(NB. Minimum number required is 8)
No
Da
te
Pla
ce
Topics Supervisor
signature
1
2
3
4
5
6
7
8
Practical skills Practical skills (Agreement Scale) of
Medical Biochemistry and Molecular Biology
Weighing and preparation of solutions
(NB. Minimum number required is 5)
No Date Place Performance Supervisor
signature
1
2
3
4
5
Buffer preparation
(NB. Minimum number required is 5)
No Date Place Performance Supervisor
signature
1
2
3
4
5
Specimen Collection and processing
(NB. Minimum number required is 5)
No Date Place Performance Supervisor
signature
1
2
3
4
5
59
Spectrophotometric assays
(NB. Minimum number required is 6)
No Date Place Performance Supervisor
signature
1
2
3
4
5
6
Urine Analysis
(NB. Minimum number required is 4)
No Date Place Performance Supervisor
signature
1
2
3
4
Urinary stone analysis
(NB. Minimum number required is 2)
No Date Place Performance Supervisor
signature
1
2
DNA extraction
(NB. Minimum number required is 2)
No Date Place Performance Supervisor
signature
1
2
60
Electrophoresis
(NB. Minimum number required is 2)
No Date Place Performance Supervisor
signature
1
2
AP =ASSISTED PERFORMANCE
IP =INDEPENDENT PERFORMANCE
O =OBSERVATION
P =POOR S= Satisfactory E= Excellent GOOD
Assignments
(NB. Minimum number required is 10)
No Date Score Topic Supervisor
signature
1 Assessment of a diabetic case by OGTT
2 Assessment of a dyslipidemic case by
spectrophotometry
3 Calculations of concentration and
dilution of solutions
4 Preparation and presentation of a
seminar (advanced biochemistry and
molecular biology)
5 Preparation and presentation of one
article in Journal club sessions
6 Design primers for a specific gene
7 Check validity of a PCR primer
sequence for a specific gene
8 Analyze the results of DNA
fingerprinting
5 - Log book preview
The candidate logbook will be reviewed and patients seen/ skills
performed summarized by diagnosis groups during the semester evaluation and at
the end of the course in the table below. The results of this review will be totaled
in the summary chart below.
61
Summary
1
st
Semester
2nd
Semester
3rd
Semester
4th
Semester
Total
Activity No No No No
Conferences
attendance
Thesis attendance
Journal club
attendance
Seminar attendance
Practical skills:
Weighing and
preparation of solutions
Preparation of buffers
Specimen collection
and processing
Spectrophotometric
assays
Urine analysis
Urinary stone analysis
DNA extraction
Electrophoresis
Assignments:
Assessment of a
diabetic case by OGTT
Assessment of a
dyslipidemic case by
spectrophotometry
Preparation and
presentation of a
seminar
Preparation and
presentation of one
article in Journal club
sessions
Design PCR primers
for a specific gene
62
Check validity of a
PCR primer sequence
for a specific gene
Analyze the results of
DNA fingerprinting
Supervisor signature
VII - Head Of Department Approval For The Exam Entry
__________________________________________________________________
__________________________________________________________________
________________________________________________________ __________________________________________________________________
____________________________ __________________________________________________________________
____________________________ __________________________________________________________________
____________________________ __________________________________________________________________
____________________________ __________________________________________________________________
____________________________ __________________________________________________________________
____________________________ __________________________________________________________________
____________________________ __________________________________________________________________
____________________________
63
VIII – Thesis Follow up
انخقزيز اننصف انسنىي نعبو / انخبريخ/
عن انطبنب /
انقيذ نذرجت ) يبجسيخز (
بقسى /
حقزيز انسبدة االسبحذة انشزفين
بذأ جع انبدة انعهيت و كخببت انقذيت
ع شىطب يحذوداقط
أوشك عه اإلنخهبء
إنخه ين انجع
بذأ انجزء انعه
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخه ين انخحهيم
بذأ ينبقشت اننخبئج
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخه ين انخحزيز
بذأ عت اننهبئيت يع انشزفانزاج
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخهج حبيب
إسخزار قيذ انطبنب رأي انسبدة انشزفين
يذ انقيذ
شطب قيذ انطبنب
نعى حى حشكيم نجنت اننبقشت
ال
ريخ انخشكيم حب
/ /
يذ / شطب انقيذ
وكيم انكهيت حىقيع انسبدة انشزفين
64
65
انخقزيز اننصف انسنىي نعبو / انخبريخ/
عن انطبنب /
ذ نذرجت ) يبجسيخز (انقي
بقسى /
حقزيز انسبدة االسبحذة انشزفين
بذأ جع انبدة انعهيت و كخببت انقذيت
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخه ين انجع
بذأ انجزء انعه
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخه ين انخحهيم
بذأ ينبقشت اننخبئج
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخه ين انخحزيز
بذأ انزاجعت اننهبئيت يع انشزف
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخهج حبيب
إسخزار قيذ انطبنب رأي انسبدة انشزفين
يذ انقيذ
ذ انطبنب شطب قي
نعى حى حشكيم نجنت اننبقشت
ال
حبريخ انخشكيم
/ /
يذ / شطب انقيذ
وكيم انكهيت حىقيع انسبدة انشزفين
66
67
انخقزيز اننصف انسنىي نعبو / انخبريخ/
عن انطبنب /
انقيذ نذرجت ) يبجسيخز (
بقسى /
حقزيز انسبدة االسبحذة انشزفين
بذأ جع انبدة انعهيت و كخببت انقذيت
قطع شىطب يحذودا
أوشك عه اإلنخهبء
ين انجعإنخه
بذأ انجزء انعه
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخه ين انخحهيم
بذأ ينبقشت اننخبئج
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخه ين انخحزيز
بذأ انزاجعت اننهبئيت يع انشزف
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخهج حبيب
إسخزار قيذ انطبنب رأي انسبدة انشزفين
يذ انقيذ
شطب قيذ انطبنب
نعى حى حشكيم نجنت اننبقشت
ال
حبريخ انخشكيم
/ /
يذ / شطب انقيذ
وكيم انكهيت حىقيع انسبدة انشزفين
68
69
انخقزيز اننصف انسنىي نعبو / انخبريخ/
عن انطبنب /
انقيذ نذرجت ) يبجسيخز (
بقسى /
السبحذة انشزفينحقزيز انسبدة ا
بذأ جع انبدة انعهيت و كخببت انقذيت
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخه ين انجع
بذأ انجزء انعه
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخه ين انخحهيم
بذأ ينبقشت اننخبئج
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخه ين انخحزيز
بذأ انزاجعت اننهبئيت يع انشزف
قطع شىطب يحذودا
أوشك عه اإلنخهبء
إنخهج حبيب
إسخزار قيذ انطبنب رأي انسبدة انشزفين
يذ انقيذ
شطب قيذ انطبنب
نعى حى حشكيم نجنت اننبقشت
ال
حبريخ انخشكيم
/ /
يذ / شطب انقيذ
وكيم انكهيت حىقيع انسبدة انشزفين
70
71
VIII – Evaluation Forms
To be completed at -------------------------------------
Candidate
Supervisor
Location
Aim of training
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Agreed educational objectives and timescale in which objectives should be
achieved.
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Comments by Candidate
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Comments by Supervisor
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Date of next meeting
Signed by candidate
Signed by Supervisor
Date
72
73
VIII – Evaluation Forms
To be completed at -------------------------------------
Candidate
Supervisor
Location
Aim of training
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Agreed educational objectives and timescale in which objectives should be
achieved.
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Comments by Candidate
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Comments by Supervisor
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Date of next meeting
Signed by candidate
Signed by Supervisor
Date
74
75
VIII – Evaluation Forms
To be completed at -------------------------------------
Candidate
Supervisor
Location
Aim of training
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Agreed educational objectives and timescale in which objectives should be
achieved.
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Comments by Candidate
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Comments by Supervisor
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Date of next meeting
Signed by candidate
Signed by Supervisor
Date
76
77
VIII – Evaluation Forms
To be completed at -------------------------------------
Candidate
Supervisor
Location
Aim of training
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Agreed educational objectives and timescale in which objectives should be
achieved.
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Comments by Candidate
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Comments by Supervisor
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
__________________________________________________________________
Date of next meeting
Signed by candidate
Signed by Supervisor
Date
78
79
Degree Program Evaluation Form by The Candidate
To be completed at the end of your degree.
Please consider each pair of statements and decide which most clearly reflects your
view and tick one box or answer the question.
I. Individual Information
1. Are you a graduate of ASU?
yes no to some degree
2. Year and semester when studies began:
II. General Questions
1. What are the advantages/disadvantages of the general study environment at the
University ASU?
2. What were your expectations when you applied to the degree?
3. Do you feel that the degree program prepares you well for your future studies or
employment according to the demands and expectations of those institutions?
yes no to some degree
4. Has the time limit of the program (two or three academic years) caused you any
difficulties or inconveniences?
yes no to some degree
III. Structure of Degree Program
1. Did you receive enough guidance in planning your study schedule in the
beginning of the program?
yes no to some degree
2. What were the main difficulties in the planning of your study schedule?
3. What is your general opinion on the structure of the degree program?
80
4. In your opinion, does the degree program offer a good balance of lectures,
seminars, conferences, and book exams?
yes no to some degree
a) General Studies
i) Do you feel that you have received enough guidance on academic writing?
yes no to some degree
ii) Do you feel that you have acquired sufficient knowledge on research skills (eg.
quantitative and qualitative research methods)?
yes no to some degree
b) Courses
i) Have you had some special difficulties in completing some of the courses?
Please specify.
ii) Has there been a sufficient variety of courses offered for your optional studies?
yes no to some degree
iii) Have you received enough guidance for the preparation of your thesis?
yes no to some degree
IV. Concluding Points
1. Did the degree program meet your expectations?
yes no to some degree
2. What aspects of the degree program do you particularly like?
3. What aspects of the degree program do you particularly dislike?
4. What are your suggestions on how to improve the program?
Thank you!