Carolina Breast Cancer Study: Breast cancer subtypes and race
Pathophysiology of Breast Cancer
2
PATHOPHYSIOLOGY OF BREAST CANCER Etiology Unknown Somatic mutations in the DNA Activate oncogene / deactivate tumor suppressor gene Neoplasm formation in the breast PREDISPOSING FACTORS: Genetics Hormonal factors Age Gender Family history PRECIPITATING FACTORS: Radiation exposure Fat intake and Obesity Alcohol use Cigarette Smoking Intake of Contraceptive Pills Primary tumor begins in the breast Travel to other organ system Progressed beyond the breast to regional lymph node. Tumor becomes invasive If treated: -Surgery -Chemotherapy -Radiotherapy Cancer cell destroyed If not treated Compromise the functions of the major organs DEATH
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Breast Cancer
Transcript of Pathophysiology of Breast Cancer
PATHOPHYSIOLOGY OF BREAST CANCER
EtiologyUnknown
Somatic mutations in the DNA
Activate oncogene / deactivate tumor suppressor gene
Neoplasm formation in the breast
PREDISPOSING FACTORS:
Genetics
Hormonal factors
Age
Gender
Family history
PRECIPITATING FACTORS:
Radiation exposureFat intake and Obesity
Alcohol useCigarette Smoking
Intake of Contraceptive Pills
Primary tumor begins in the breast
Travel to other organ system
Progressed beyond the breast to regional lymph node.
Tumor becomes invasive
If treated: -Surgery-Chemotherapy-Radiotherapy
Cancer cell destroyed
If not treated
Compromise the functions of the major organs
DEATH