Outside the Net-94359-30519 (4)

Anti Malaria Fashion Foundation

Outside the Net Personal Protection Project towards elimination of residual transmission

Anti Malaria Fashion Foundation 2015

-Nature, Sept 2015 “Effect of malaria control on Plasmodium falciparum in Africa 2000 – 2015” S.Bhatt, D.J.Weiss, E.Cameron

50% reduction in Pf infection prevalence40% reduction in clinical disease incidence668 million cases averted over 15 years

Persistence of Malaria187 million clinical cases in 2015

Attributable effects of control measures68% Insecticide Treated Nets (ITNs)19% Artemisinin Combination Therapy (ACT)13% Insectide Residual Spraying (IRS)

Anti Malaria Fashion Foundationtowards elimination of residual transmission


towards elimination of residual transmission

Harar, Ethiopia

Block inside biting mosquitoes at night

Kill landing mosquitoes (permethrin)

Industrially impregnated net material for lasting effect


Long Lasting Insecticidal Nets (LLIN)


Resistance

Mosquito resistance to pyrmethrin detected

Three new classes of insecticides needed (IVCC)

Residual transmission remains- outside the net biting

Anti Malaria Fashion Foundation

2015

-Nature, Sept 2015 “Effect of malaria control on Plasmodium falciparum in Africa 2000 – 2015” S.Bhatt, D.J.Weiss, E.Cameron

Highlights “This analysis demonstrates current malaria interventions have

been highly effective at reducing prevalence and incidence……Provides strong support for sustaining and increasing access to these interventionsRedoubling of efforts to delay the spread of drug and insecticide resistanceTools needed to address residual transmission that persists in areas of high vector control efforts”

Anti Malaria Fashion Foundationtowards elimination of residual transmission



-Malaria Journal 2015‘A bite before bed’: exposure to malaria vectors outside the times of net use in the highlands of western Kenya

Mary K Cooke Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK

Results and conclusions“overlap of early biting habit of vectors and human

activity in this region indicates that additional methods of vector control are required to limit transmission”

Anopheles gambiae



Mosquito and human behavior vary by location

Evening meal preparations in central Malawi

Biting times and locations PovertyInsecticide resistance DwellingsSelection of outdoor biting Livelihoodsand resting behaviors Customs

Anopheles funestus



Categories of Vector Control Measures Complementary to LLINs IRS & ACT

Outside sprayingLarvacidesTrapsSterile mosquitoesProtective clothing and repellents


Protective clothingEfficacy with consistent use

Refugee camp studies (Kenya, Afghanistan)US ArmyPymethrin most common

Industrial pretreatment of clothing (uniforms)Imperfect measures of efficacy (no standard methods)


- Medical and Veterinary Entomology(2014) Insecticide-treated clothes for the control of vector-borne diseases: a review on effectiveness and safetyS. D. BANKS Department of Disease Control, London School of Hygiene and Tropical Medicine

“Under the correct circumstances, insecticide-treated clothing is a promising intervention against disease transmission, but further studies are needed to define the most appropriate guidelines for testing insecticide-treated clothing.”

“The utilizing of existing clothing and habits promotes stronger compliance and greater acceptability.”

“If treated clothing does actively repel arthropods, it may provide protection even in places where physiological resistance to pyrethroids is found.”



“Under the correct circumstances, insecticide-treated clothing is a promising intervention against disease transmission” S. D. BANKS Department of Disease Control, London School of Hygiene and Tropical Medicine


Effective protection: treated clothing and protective skin products


“Under the correct circumstances, insecticide-treated clothing is a promising intervention against disease transmission” S. D. BANKS Department of Disease Control, London School of Hygiene and Tropical Medicine

Areas with effective LLINs and IRS

Areas with emergent resistance

Easy to implement clothing treatment program


Compliance not a problem for an Army with pretreated uniforms


“The utilizing of existing clothing and habits promotes stronger compliance and greater acceptability.”S. D. BANKS Department of Disease Control, London School of Hygiene and Tropical Medicine



“The utilizing of existing clothing and habits promotes stronger compliance and greater acceptability.”S. D. BANKS Department of Disease Control, London School of Hygiene and Tropical Medicine


Mulago Hospital, Kampala

Civilians need a different solution – insecticidal treatment for existing clothes

Simple insecticidal treatment of personal clothing in the field

-soak and dry manually or use washing machine

Safe to use, safe to wear (IR3535)

Sleeping blankets, wraps, bed nets

Effective against mosquitoes and other insects

Implement using existing LLINs and IRS infrastructure, village health committees


towards elimination of residual transmissionOutside the Net Personal Protection Project

Mozzie Armor® clothing treatment

Mozzie Armor® clothing treatment


towards elimination of residual transmissionOutside the Net Personal Protection Project

Long lasting protection – 60 to 80% effective after 20 industrial washes

-nano technology formulation -addresses permethrin resistance today-adaptable to alternative pesticides and

repellents

Mozzie Armor Textile® formulation

Treatment of textiles before clothing manufactureLong lasting protection – 60 to 80% effective after 50 industrial washes

-uniforms of all types



Anti Malaria Fashion FoundationOutside the Net Personal Protection Project

Extend protection from vector transmission to outside the net

Early evening, early morning hours

Outside biting activity

Emerging resistance to pyrethroids, physiologic and behavioral

Implement and test insecticide treated clothing solutions

Field treatment of civilian clothing. Pretreatment of uniforms and work clothes. Integrate into malaria control programs. ‘Push-pull’ intervention.



Anti Malaria Fashion FoundationOutside the Net Personal Protection Project

Contact:

Nelly Kolodny, PhDAnti Malaria Fashion Foundation240-401-2959www.antimalariafoundation.org

http://www.antimalariafoundation.org/

Outside the Net-94359-30519 (4)

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