Novel Synthesis of 7-Fluoro-8-(trifluoromethyl)-1H-1,6-naphthyridin-4-one Derivatives:...

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2007 Fused pyridine derivatives R 0450 Novel Synthesis of 7-Fluoro-8-(trifluoromethyl)-1H-1,6-naphthyridin-4-one De- rivatives: Intermolecular Cyclization of an N-Silyl-1-azaallyl Anion with Perfluo- roalkene and Subsequent Intramolecular Skeletal Transformation of the Result- ing Pentasubstituted Pyridines. — The title naphthyridinones are of biological inter- est. — (SUZUKI, H.; SAKAI, N.; IWAHARA, R.; FUJIWAKA, T.; SATOH, M.; KAKEHI, A.; KONAKAHARA*, T.; J. Org. Chem. 72 (2007) 15, 5878-5881; Dep. Pure Appl. Chem., Fac. Sci. Technol., Sci. Univ. Tokyo, Noda, Chiba 278, Japan; Eng.) — Jannicke 49- 164

Transcript of Novel Synthesis of 7-Fluoro-8-(trifluoromethyl)-1H-1,6-naphthyridin-4-one Derivatives:...

Page 1: Novel Synthesis of 7-Fluoro-8-(trifluoromethyl)-1H-1,6-naphthyridin-4-one Derivatives: Intermolecular Cyclization of an N-Silyl-1-azaallyl Anion with Perfluoroalkene and Subsequent

2007

Fused pyridine derivativesR 0450 Novel Synthesis of 7-Fluoro-8-(trifluoromethyl)-1H-1,6-naphthyridin-4-one De-

rivatives: Intermolecular Cyclization of an N-Silyl-1-azaallyl Anion with Perfluo-roalkene and Subsequent Intramolecular Skeletal Transformation of the Result-ing Pentasubstituted Pyridines. — The title naphthyridinones are of biological inter-est. — (SUZUKI, H.; SAKAI, N.; IWAHARA, R.; FUJIWAKA, T.; SATOH, M.; KAKEHI, A.; KONAKAHARA*, T.; J. Org. Chem. 72 (2007) 15, 5878-5881; Dep. Pure Appl. Chem., Fac. Sci. Technol., Sci. Univ. Tokyo, Noda, Chiba 278, Japan; Eng.) — Jannicke

49- 164

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N-(4-(2-Chloro-4-(trifluoromethyl)phenoxy)phenyl ... · N-(4-(2-Chloro-4-(trifluoromethyl)phenoxy)phenyl)picolinamide as a new inhibitors of mitochondrial complex III: Synthesis,

Catalytic Prins Cyclization using In(OTf) 3 and Silyl ...cbc/cv/teckpeng/Prof Loh Research Highlight… · highly diastereoselective Prins cyclization. Re-duced epimerization was

Catalytic Prins Cyclization using In(OTf) 3 and Silyl ...cbc/cv/teckpeng/Prof Loh Research Highlight… · highly diastereoselective Prins cyclization. Re-duced epimerization was

REPORT NUMBER III SYNTHESIS OF p-TRIFLUOROMETHYL …

REPORT NUMBER III SYNTHESIS OF p-TRIFLUOROMETHYL …

Aryldisilane Photochemistry. The Role of Silyl Free ...wjl/leigh/publications/om_13_1005_1994.pdfOrganometallics 1994,13, 1005-1013 1005 Aryldisilane Photochemistry. The Role of Silyl

Aryldisilane Photochemistry. The Role of Silyl Free ...wjl/leigh/publications/om_13_1005_1994.pdfOrganometallics 1994,13, 1005-1013 1005 Aryldisilane Photochemistry. The Role of Silyl

Pd-Catalyzed Borylative Cyclization Reactions of ...

Pd-Catalyzed Borylative Cyclization Reactions of ...

Enantioselective Polyene Cyclization via Organo-SOMO Catalysischemlabs.princeton.edu/macmillan/wp-content/uploads/... · 2016-12-24 · Enantioselective Polyene Cyclization via Organo-SOMO

Enantioselective Polyene Cyclization via Organo-SOMO Catalysischemlabs.princeton.edu/macmillan/wp-content/uploads/... · 2016-12-24 · Enantioselective Polyene Cyclization via Organo-SOMO

On the Effect of Cyclization on Peptide Backbone Dynamics377355/UQ... · backbone cyclization can improve rigidity, there is a complex interplay between dynamics and cyclization,

On the Effect of Cyclization on Peptide Backbone Dynamics377355/UQ... · backbone cyclization can improve rigidity, there is a complex interplay between dynamics and cyclization,

Synthesis and properties of (trifluoromethyl) phosphinohydrazines

Synthesis and properties of (trifluoromethyl) phosphinohydrazines

Science of Synthesis KnowledgeUpdates 2020/3...4.4.28.17.9 Synthesis of a-Silyl Amines from Silylmethyl Azides ..... 37 4.4.28.17.9.1 Method 1: a -Silyl Amines by Ruthenium-Catalyzed

Science of Synthesis KnowledgeUpdates 2020/3...4.4.28.17.9 Synthesis of a-Silyl Amines from Silylmethyl Azides ..... 37 4.4.28.17.9.1 Method 1: a -Silyl Amines by Ruthenium-Catalyzed

Reductive Cyclization Products Of

Reductive Cyclization Products Of

Tunable Bifunctional Silyl Ether Cross-Linkers for the Design

Tunable Bifunctional Silyl Ether Cross-Linkers for the Design

Silyl effusion from plasma-produced silicon nanocrystals · Silyl effusion from plasma-produced silicon nanocrystals ... corresponding to changes in the Si-Hx bonds at ... passivation

Silyl effusion from plasma-produced silicon nanocrystals · Silyl effusion from plasma-produced silicon nanocrystals ... corresponding to changes in the Si-Hx bonds at ... passivation

A Highly Diastereoselective ‘Super Silyl’ Governed …...A Highly Diastereoselective ‘Super Silyl’ Governed Aldol Reaction: Synthesis of α,β-Dioxyaldehydes and 1,2,3-Triols

A Highly Diastereoselective ‘Super Silyl’ Governed …...A Highly Diastereoselective ‘Super Silyl’ Governed Aldol Reaction: Synthesis of α,β-Dioxyaldehydes and 1,2,3-Triols

Ulm, - univie.ac.atmulzer.univie.ac.at/fileadmin/user_upload/ag_rg_mulzer/...Cyclizations onto acyclic alkenes Axially chiral induction Cascade cyclization 6-exo-cyclization Cascade

Ulm, - univie.ac.atmulzer.univie.ac.at/fileadmin/user_upload/ag_rg_mulzer/...Cyclizations onto acyclic alkenes Axially chiral induction Cascade cyclization 6-exo-cyclization Cascade

Trifluoromethyl ethers synthesis and properties of an unusual … · Page 1 of (page number not for citation purposes) 15 Trifluoromethyl ethers – synthesis and properties of an

Trifluoromethyl ethers synthesis and properties of an unusual … · Page 1 of (page number not for citation purposes) 15 Trifluoromethyl ethers – synthesis and properties of an

Cascade condensation, cyclization, intermolecular dipolar

Cascade condensation, cyclization, intermolecular dipolar

ZJ1 - Virginia Tech · 2020. 9. 28. · Desorption Temperatures of Bis(trifluoromethyl) Disulfide from Nickel ..... 93 XXVII. Mass Spectrum of Bis(trifluoromethyl) Disulfide at Constant

ZJ1 - Virginia Tech · 2020. 9. 28. · Desorption Temperatures of Bis(trifluoromethyl) Disulfide from Nickel ..... 93 XXVII. Mass Spectrum of Bis(trifluoromethyl) Disulfide at Constant

Alcohols. Tetrahydropyranyl Ethers to Silyl-protected One ... · One-step Chemoselective Conversion of Tetrahydropyranyl Ethers to Silyl-protected Alcohols. Julian Bergueiro, Javier

Alcohols. Tetrahydropyranyl Ethers to Silyl-protected One ... · One-step Chemoselective Conversion of Tetrahydropyranyl Ethers to Silyl-protected Alcohols. Julian Bergueiro, Javier

Nickel-Catalyzed Coupling of Alkenes, Aldehydes, and Silyl ... › ~joyce › referance › payfor › J. Am... · Nickel-Catalyzed Coupling of Alkenes, Aldehydes, and Silyl Triflates

Nickel-Catalyzed Coupling of Alkenes, Aldehydes, and Silyl ... › ~joyce › referance › payfor › J. Am... · Nickel-Catalyzed Coupling of Alkenes, Aldehydes, and Silyl Triflates

Synthesis of 3-Trifluoromethyl-3-Pyrimidinyl Diazirines as ...m044f1817/fulltext.pdfiodo amino acid to form a novel amino acid analog. Since trifluoromethyl diazirines can be ... The

Synthesis of 3-Trifluoromethyl-3-Pyrimidinyl Diazirines as ...m044f1817/fulltext.pdfiodo amino acid to form a novel amino acid analog. Since trifluoromethyl diazirines can be ... The