NİLGÜL NALBANTCoordinator of Seminar : Mersini Makropoulou

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Laser – Tissue Interactions

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CONTENT:

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What is the CARDIOLOGY? CARDIOLOGY is a science which

researches anatomy, physiology and pathology of the heart and the vessels.

Disturbances in the heart and vessels are diagnosed and treated by CARDIOLOGY.

All important diseases are defined by CARDIOLOGY.

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Laser Angioplasty

Laser Angioplasty is one of the methods which is used for defining the injuries.

At the Laser Angioplasty, light energy is transferred to the tissue.

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The transfer of the light energy into a tissue depends on three factors: The wavelength of the light Its power density The chemical and physical

properties of the target

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Photon energy in electron-volts of some lasers currently in use or under investigation for medical applications.

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The absorption of the laser radiation by the tissue is given by the equation:

I* = I e-αL

I* = Intensity of the light transmitted

I= Intensity of the light beam

α= absorptivity of the target tissue

L= thickness of the tissue

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If the absorption is strong, the photons penetrate to depth of only 1/10th to 1/100th of a mm from the tissue surface.

Strong absorption tends to minimize the thermal damage to the underlying areas because the diffusion of heat from the laser photons is minimized.

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The density of the photon stream or power density is one of two factors that control the density of excited molecules in the tissue the instant the light beam strikes.

At the power levels at which lasers operate, the laser- tissue interaction is by no means limited to given molecule’s being excited by just one photon.

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Time(sn)

Photochemicalreactions

coagulation

Vaporization

Photo ablation

photoabsorption

This is explain by:

Fluence = Energy deposited/ area

Power density = Energy deposited / time

Power density = Fluence / time

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The overall process of using the photon energy of pulsed laser to cause a transformation in a tissue can be sorted into three individual step:

1. Absorption of the photon

2. Bond breaking

3. Ablation of the products

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Irradiation

Absorption

Bond Breaking

Ablation

Laser Beam

Mask

Tissue

Long- chain Molecules

What are advantages of The Laser in the Angioplasty?

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1)It differentiates the damaged vessel from the normal vessels.

2)It is used at the tissue catheterization.

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ANGIOPLASTY

KOCAELİÜNİVERSİTESİTIP F. –CARDIOLOGY LABORATORY

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ANGIOPLASTY

KOCAELİÜNİVERSİTESİTIP F. –CARDIOLOGY LABORATORY

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Anatomic appearance Angiographical appearance

Narrowed artery

THE ROLE OF ULTRASOUND IN THE INTERVENTIONAL CARDIOLOGY Dr.Cevdet ERDÖL, Doc.Dr.Nazim A R S L A N , Prof.Dr.Dcnlz DEMlRKAN GATA Cardiology ABD, ANKARA

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