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Improving public health - does research have an influence?
www.helsinki.fi/yliopisto
Mikael Fogelholm, Professor in Nutrition
Department of Food and Environmental Sciences
4.10.2011
Faculty of Agriculture and Forestry
Department of Food and Environmental Sciences 1
Health-related grand challenges for European research: age distribution
60 %
80 %
100 %
80+
65-79
www.helsinki.fi/yliopisto
0 %
20 %
40 %
60 %
1950 1975 2000 2025 2050
50-64
25-49
15-24
0-14
Health-related grand challenges for European research: dementia
30
40
Dementia
www.helsinki.fi/yliopisto
0
10
20
60 70 80 90 100
Age (years)
Stroke
Parkinson
%
15
20
25
% with
Health-related grand challenges for European research: obesity
www.helsinki.fi/yliopisto 4.10.2011
0
5
10
67 71 74 77 80 84 85 86 94 95 98 99 2 3
% with
overweight
Overweight among adolescents (12-18 y) in Nordic
countries between years 1967 and 2003.
Health-related grand challenges for European research: type 2 diabetes
25
30
35
Non-obese Obese
Type 2 diabetes
in Finland
• 1970: 50 000
www.helsinki.fi/yliopisto 4.10.2011 5
0
5
10
15
20
46-50 36-40 26-30 46-50 36-40 26-30
Birth year (19..)
%• 1970: 50 000
• 2010: 200 000
• 2030: 400 000?
The proportion (%) of type 2 diabetics among obese
(BMI>30) and non-obese (BMI<30) in Päijät-Häme
(Lahti region), South Finland.
Joint programming perspectives and motivation
l Harmonizing strategic research approaches within countries to
tackle more efficiently societal challenges
l Synergistic use of shrinking research budgets in a difficult
economic climate
www.helsinki.fi/yliopisto 4.10.2011 6
economic climate
l Grouping calls for grants at the level of several member states on
a voluntary basis will reinforce the potential for scientific
collaboration in Europe
l Accountability to stakeholders in pooling research efforts
addressing common social issues in Europe
l Simplifying European procedures governing scientific collaboration
(and its administration)
Health-related Joint Programming topics
Neurodegenerative diseases, in particular Alzheimer’s
disease
More Years, Better Lives - The Potential and
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More Years, Better Lives - The Potential and
Challenges of Demographic Change
A healthy diet for a healthy life
The microbial challenge – an emerging threat to
human health
4.10.2011 7
A healthy diet for a healthy life
Policy and societal challenges
• Social inequalities
• Young generation & elderly
• Obesity, type 2 diabetes
www.helsinki.fi/yliopisto 4.10.2011 8
• Obesity, type 2 diabetes
• Determinants of choices & health
• Food supply
• Sustainable & reasonable price
• Competitiveness of food industry
A healthy diet for a healthy life
How to change?
Understanding of
• Individual differences
• Relationships between habits-onset disease
www.helsinki.fi/yliopisto 4.10.2011 9
• Relationships between habits-onset disease
• Mechanisms
• Genetic basis
• Needs due to social inequalities
‒ Minority groups
• Social environments
• Validation of health claims
• Share databases and large intervention studies
• European Food Research Institute?
A healthy diet for a healthy life
Research needs identified
www.helsinki.fi/yliopisto 4.10.2011 10
• European Food Research Institute?
• European network on Food-omics
• Long-term European multi-centre intervention studies
• Standardization of investigation procedures and designs
Good Ageing in Lahti Region (GOAL),
Finnish research project on ageing and
well-being
www.helsinki.fi/yliopisto 4.10.2011 11
The province of Paijat-Hame in the beginning of GOAL (y. 2000)
� Low-tech industry characteristic for town of Lahti, agriculture for the rural areas
� High unemployment rate
� Ageing rapidly
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� Ageing rapidly
� Relatively poor health status
� Unhealthy lifestyles, high BMI
� Municipalities having great economic difficulties, pressure to organizational changes
� Health care sector operating with lowest costs in the country; and with rapidly ageing personnel
Hämeenkoski
Iiitti
Orimattila
Nastola
Lahti
Pukkila
Hollola
Proportion of 65-74 –y old in Päijät-Häme, yr. 2000
(pink) and 2015 (light blue, predicted)
22.6.2006
0 5 10 15 20
Hartola
Padasjoki
Sysmä
Asikkala
Heinola
Kärkölä
Artjärvi
Hämeenkoski
Finland, 2015Finland, 2000
Good Ageing in Lahti Region (GOAL), Finnish research project on ageing and well-being
Collaborators �University of Helsinki, Palmenia
�University of Helsinki, Dept. ofSocial Policy
www.helsinki.fi/yliopisto 4.10.2011 14
Social Policy
�University of Helsinki, Division ofNutrition
�National Institute for Health andWelfare
� Lahti Polytechnic (University ofApplied Sciences)
�Päijat-Hame Hospital District andits 15 municipalities
Good Ageing in Lahti Region (GOAL), Finnish research project on ageing and well-being: goals
To empower both the population and the professionals in health promotion
www.helsinki.fi/yliopisto 4.10.2011 15
And as a consequence
To increase welfare, diminish morbidity, and improve quality of life among ageing population in Lahti Region
1) 10-year cohort study (2002-2012)
� three birth cohorts (baseline n=2815) will be followed,
those born in 1946-50, 1936-40 and 1926-30
� needs assessment
general program evaluation
Good Ageing in Lahti Region (GOAL), Finnish research project on ageing and well-being: the three parts
www.helsinki.fi/yliopisto 4.10.2011 16
� general program evaluation
2) Community-based interventions (2002-2012)
� evidence-based
� implementation studies
� development of policies and practicies
3) Community Diagnoses (2002)
� combining data from cohort study, statistical reports and
policy documens from each municipality
Self-reported health compared to 1 year earlier(GOAL cohort, 2005)
60 %
80 %
100 %
Worse
Similar
www.helsinki.fi/yliopisto 4.10.2011 17
0 %
20 %
40 %
46-50 36-40 26-30 46-50 36-40 26-30
Year of birth (19..)
Similar
Better
Ikihyvä Päijät-Häme, interim report 2005 (Fogelholm et al. 2007)
Self-reported difficulties in performing activities
related to daily living in women, born 1926-30,
1936-40 and 1946-50.
0 10 20 30 40 50 60 70 80 90 100
Bathing/dressing
Walk 100 m
Walk 500 m
Stairs 1 floor up
%
Stairs 1 floor up
Walk 2 km
Carrying food-bag
Moderate exertions
Kneeing/bending
Stairs several floors
Vigorous activities
1946-50
1936-40
1926-30
Ikihyvä Päijät-Häme, interim report 2005 (Fogelholm et al. 2007)
Proportion of individuals with severe restrictions in walking 500 m or bending, according to local community type. Results are adjusted for age and sex.
12
14
16
18
20
Urban
* *
%
* = p<0.001
vs. other
www.helsinki.fi/yliopisto 4.10.2011 19
0
2
4
6
8
10
12
Walking 500 m Bending
Urban
Semi-urban
Rural
Fogelholm et al. Scand J Publ Health, 2006
%
Intervention I: Group-counselling for prevention of T2D and CVD, based on The Health Action Process Approach. 1-y results.
Intervention goals GOAL, %
N=352
DPS, %
N=265
Total fat < 30E% 48 47
SFA < 10E% * 34 26Those achieving 4-
5 goals had
www.helsinki.fi/yliopisto
SFA < 10E% * 34 26
Fibre > 15g/1000 kcal*** 52 25
Exercise > 30 min / d*** 66 86
Weight loss > 5% *** 12 43
4-5 goals achieved 20 18
5 goals had
significantly more
often normal
glucose tolerance at
1-y follow-up
(χ2 = 7.120, p < 0.05)
Absetz et al. Diabetes Care 2007, 30, 2465-2470.
Community health-care3rd sector
Health Action Process Approach
Motivation
Interventions
• Social networking
• Strength and
Identification of
individuals with
mobility
Intervention II: Identification and counselling for individuals with impaired physical functioning
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Motivation
Empowerment• Strength and
balance training
• Nutrition
mobility
problems
To the intervention
Back to health care for follow-up measurements
Lessons learned from GOAL
� Emphasis shifted from individual towards social and health care sector and municipal administration as primary targets
� Sensitivity to emerging intervention needs
www.helsinki.fi/yliopisto 4.10.2011
Maatalous-metsä tieteellinen tiedekunta / Henkilön
nimi / Esityksen nimi 22
� Sensitivity to emerging intervention needs
� Interventions support each other ideologically, structurally and methodologically
� During its brief history, GOAL has established itself as a developmental resource in Päijät-Häme – but it takes time to overcome resistance!