NERSA Public Hearings

Devan Pillay

Consumer Health DivisionHead of Engineering: Africa

20 January 2010

South Africa

The Problem…

0.5 1.050.7 1.5

0.5 2010 2011 2012

Our response…2009

Elephantiasis

Relatively uncommon late complication of filariasis

Death of worms causes calcification and obstruction

Recurrent secondary bacterial and fungal infections play a very important role

A Disease Of Devastating Proportions

80 endemic countries

1.2 billion people at risk

120 million people affected

An infection of children

1 million children infected each year

Children become infected when very young

but usually appear healthy

The latency period is long: visible symptoms

present in puberty

Diagnostic tools can detect early infection

Of all LF sufferers, children will benefit most

from the elimination programme

GSK’s Commitment

The industry’s largest donation programme

5 -7 billion tablets of albendazole over 20+ years

Providing valuable financial support to essential, operational research

Progress1013 million albendazole tablets to 48 countries by end of 2008

Cumulative Treatments Donated

0

200

400

600

800

1000

1200

1999 2000 2001 2002 2003 2004 2005 2006 2007 2008

Year

Mil

lio

ns

Series2

Albendazole LF - pack of 100 Tablets 2010 2010 2010

 Nashik

(£)Cape Town

(£)Cape Town

(£)

Total Cost of Production 1.20 1.32 1.35

% Difference in cost against Nashik 10 13

In Summary

Above inflationary increases make companies less competitive in the market place.

Gradual ‘Leakage’ of jobs to lower cost structured economies

Alternative funding mechanism to the increase needs to be sought

Defeats the work done in the last 10-12 years to bring us where we are today…

What did you do to save

energy today?Questions ??