Mr Basim Matti FRCS London Dr Peter Everts PhD Eindhoven, Holland
31
Mr Basim Matti FRCS London Dr Peter Everts PhD Eindhoven, Holland
description
Mr Basim Matti FRCS London Dr Peter Everts PhD Eindhoven, Holland. Mr Matti 31 Patients. Data Set as of 1 st November 2011. PRP. PRP is an autologous blood product with a high concentration of platelets. - PowerPoint PPT Presentation
Transcript of Mr Basim Matti FRCS London Dr Peter Everts PhD Eindhoven, Holland
Mr Basim Matti FRCS London Dr Peter Everts PhD Eindhoven, Holland
Mr Matti 31 Patients
Data Set as of 1st November 2011
PRP
PRP is an autologous blood product with a high concentration of platelets.
The platelets produce a cocktail of Cytokines and Growth Factors, which trigger and accelerate the regeneration of tissues.
PRP
It is concentration of human platelets in a small volume of plasma measured > than1,000,000 platelets /mm³ = 4-6x the normal
Normal value of platelet concentration in whole blood150,000-400,000mm³
Aim Of PRP Therapy
Regeneration of collagen and Elastine fibres
Prevention of collagen degradations
Rejuvenation of the skin
Wound healing principles
Platelet physiology
Platelet activation
Growth Factors
Platelet Rich Plasma Concentration of Growth Factors
PDGR – 130 times Platelet derived Growth Factor
TGF beta – 80 timesTransforming Growth Factor-beta.
VEGF – 11 timesVascular Endothelial Growth Factor
IGF 1 Insulin like Growth Factor, HGF Hepatocyte GF, Basic Fibroplasten GF
How Growth Factor Works
Areas for injection
Injection sites into dermal layer
and dermal junction
Source: Seishin Institute Japan
• >12,000 patients undergone PRP Therapy
• “NEW PRP Skin Regeneration Therapy,• three to five times richer in
platelets than conventional PRP therapy
• inject platelet-rich plasma containing white blood cells. “
http://www.saiseiiryou.com
Seishin Institute Japan.
Hyaluronic Acid
PRP
Cytomedix Angel System
Enclosed Point of Care System
Automatic collection of PRP
Peripheral blood Platelet level 276.000mm³ Dense Platelet
concentration 2.750.000mm ³ using Angel™ System
Other Test Tube systems
Our PRP Technique
52ml blood draw8mls citrate ACD-AAngel processing 18 minutesPRP yield 2mls highly concentratedaverage 12.2 x baseline platelets
Add 4mls platelet poor plasma= 6mls PRP injected with platelet concentration >850.000mm³ >3-4 x baseline platelet concentration
Video: Procedure 56secs www.youtube/avancemedical/final_edit_5th_November
Our Experience: Cohort n31
8 wksPostPre
Source: Sclafani A.P. (2010) Platelet Rich Fibrin Matrix for improvement of deep naso-labial folds . Journal of Cosmetic Dermatology , Vol.9: 66-71
Sclafani A.P. (2011) Safety, Efficacy and Utility of Platelet Rich Fibrin Matrix ARCH Facial Plastic Surgery Published on line Feb 2011 doi:10.1001/archfacial.2011.3Sclafani A.P. (2009) Applications of Platelet Rich Safety, Fibrin Matrix in Facial Plastic Surgery Facial Plastic Surgery Vol 25 No. 4
Patient Questionnaire
Key questions:Improvement in tone of skinImprovement in texture of skinReduction in linesImproved ‘glow’ or radiance of the skinVolumetric improvement ????
PATIENT SURVEY
Respondents 21 patients19% (4 patients) see no difference81% (17 patients) see and feel a difference in skin tone and texture.42.86% (9 patients) state they see a marked improvement in skin tone, texture and reduction of lines.38.1% (8 patients) extremely satisfied with the results.
Age Distribution
< 40yrs 40-50yrs
51-60yrs
>61 yrs
0
2
4
6
8
10
12
14
Number of patients 31n
Number of patients
Further Research
Number & intervals of treatmentsLongevity of treatmentCombination therapiesMicro needlingMesotherapyUltrasound
Cost of treatmentIs it worth it?
barbados meatingTHANK YOU
Thank you
