Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities,...

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Monthly Healthcare Review April 2017 Company Name Last Financing Date HQ Location Description Last Financing Size (Millions) Lead Manager Zymeworks (ZYME) 28-Apr-17 Vancouver, Canada Developer of antibodies and protein therapeutics for the treatment of cancer, autoimmune and inflammatory diseases. 58.5 Barclays Capital, Citigroup Global Markets Canada, Wells Fargo Securities Tocagen (TOCA) 12-Apr-17 San Diego, CA Developer of cancer-selective gene therapies designed to activate a patient's immune system to fight against their own cancer from within. 0.85 Evercore Group, Leerink Partners, Stifel Nicolaus & Company BerGenBio (BGBIO) 7-Apr-17 Bergen, Norway Developer of small molecule cancer drugs designed to treat aggressive cancers. 47.08 ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals, and healthcare IPO pricings, filings and withdrawals announced over the previous month. IPOs Compiled by: Lea Keller and Morgan Reape Source: Pitchbook 1

Transcript of Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities,...

Page 1: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company NameLast Financing

DateHQ Location Description

Last

Financing

Size

(Millions)

Lead Manager

Zymeworks (ZYME) 28-Apr-17

Vancouver,

Canada

Developer of antibodies and protein therapeutics for the treatment of cancer, autoimmune

and inflammatory diseases. 58.5

Barclays Capital,

Citigroup Global

Markets Canada,

Wells Fargo

Securities

Tocagen (TOCA) 12-Apr-17 San Diego, CA

Developer of cancer-selective gene therapies designed to activate a patient's immune system

to fight against their own cancer from within. 0.85

Evercore Group,

Leerink Partners,

Stifel Nicolaus &

Company

BerGenBio (BGBIO) 7-Apr-17

Bergen,

Norway Developer of small molecule cancer drugs designed to treat aggressive cancers. 47.08

ABG Sundal Collier

ASA, Arctic

Securities, DNB

Markets

The following table includes the medical devices, biotechnology, pharmaceuticals, and healthcare IPO pricings, filings and withdrawals announced over the previous month.

IPOs

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 1

Page 2: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Epic Sciences 28-Apr-17 San Diego, CA Later Stage VC

Developer of diagnostic tests designed to enable the rapid and non-

invasive detection of genetic and molecular changes in cancer

throughout a patient's journey. 0.40

Hermed Capital, Altos

Capital Partners,

Domain Associates,

Genomic Health,

Pagoda Asset

Management, Reach

Tone, RMI Partners,

Sabby Capital, VI

Ventures

Congenica 27-Apr-17

Cambridge, United

Kingdom Early Stage VC

Developer of a clinical genome analysis platform designed to process

genome wide data sets to detect mutations by filtering clinically

relevant variants and deep clinical phenotyping. 9.87

Cambridge Innovation

Capital, Amadeus

Capital Partners,

Parkwalk Advisors, BGI

Genomics, Healthlink

Capital and Future

Planet Capital

BlueStar HonorCare 27-Apr-17 Rockville, MD Angel

Provider of medical alert systems, health monitoring devices and

personal safety devices that enable seniors, elders and veterans to stay

connected and allow family members to monitor their health. 1.33 Undisclosed Investors

Avedro 27-Apr-17 Waltham, MA Later Stage VC

Operator of a pharmaceutical and medical device company intended

to advance the treatment of eye conditions, such as keratoconus and

corneal ectasia, through the continued innovation of its cross-linking

technology and family of Riboflavin products. 0.42

HealthQuest Capital,

OrbiMed, InterWest

Healthcare Partners

One Stone Technology 26-Apr-17 Cazenovia, NY Angel

Developer of a patient engagement software designed for activating

patients through personalized messaging. 0.25 Undisclosed Investors

Medicortex 26-Apr-17 Turku, Finland Angel

Developer of biomarker diagnostics that evaluate the extent and

severity of traumatic brain injury. 0.21 Invesdor

Learning Health 26-Apr-17 Tiburon, CA Angel

Provider of a healthcare management platform that allows users to

access prescribed treatments. 0.58 Undisclosed Investors

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 2

Page 3: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Jump Technologies 26-Apr-17 Eagan, MN

PE Growth/

Expansion

Developer of cloud-based mobile supply chain software intended to

improve the way supplies are managed from demand through use and

replenishment. 3.50

Black Granite Capital,

Undisclosed Investors

Evidation Health 26-Apr-17 San Mateo, CA Early Stage VC

Developer of a technology and services platform designed to

accelerate and enhance outcomes research through virtualized

pragmatic trials. 0.10

Sanofi Genzyme

BioVentures, GE

Ventures, B Capital

Group

Arsanis 26-Apr-17 Waltham, MA Later Stage VC

Developer of monoclonal antibodies designed to prevent and treat

serious infectious diseases by targeting specific pathogens or their

virulence mechanisms to avoid pathogenic processes. 45.50

Bill Melinda Gates

Foundation, GV,

Alexandria Real Estate

Equities, OrbiMed,

Polaris Partners, SV

Health Investors,

NeoMed Management,

EMBL Ventures, Anna

Maria & Stephen Kellen

Foundation

Allotrope Medical 26-Apr-17 Houston, TX Seed Round

Developer of a surgical device designed to identify and localize

ureters. 0.35

Houston Health

Ventures, Houston

Angel Network

AIdoc 26-Apr-17 Tel Aviv, Israel Early Stage VC

Developer of an artificial intelligence and deep learning platform that

analyzes medical images and patient's clinical information in order to

detect critical abnormalities, as well as integrates all relevant diagnostic

and clinical data into a comprehensive patient view. 0.07

TLV Partners, Magma

Ventures, Emerge

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 3

Page 4: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Zebra Medical Vision 25-Apr-17

Kibbutz Shefayim,

Israel Early Stage VC

Provider of a medical imaging research and analytics platform

designed to provide automated, accurate and timely medical image

diagnosis. Undisclosed

Intermountain

Healthcare, Dolby

Family Ventures,

OurCrowd First,

OurCrowd, Marc

Benioff, Khosla

Ventures

Two Pore Guys 25-Apr-17 Santa Cruz, CA Later Stage VC

Developer of a digital, hand-held and single-molecule biosensor

designed to detect virtually any kind of molecule with very high

sensitivity. 24.50 Khosla Ventures

Top Doctors 25-Apr-17 Barcelona, Spain Later Stage VC

Developer of a medical app designed to find world-class doctors and

medical centers. 3.21

Addventure,

Undisclosed Investors

Science 37 25-Apr-17 Los Angeles, CA Later Stage VC

Developer of a cloud-based, patient-centric mobile research platform

that connects participants in clinical trials. 0.29

Glynn Capital

Management, GV,

Amgen Ventures, Lux

Capital, Redmile Group,

DRX Capital, Sanofi

Ventures

Respira Therapeutics 25-Apr-17 Albuquerque, NM Later Stage VC

Developer of inhaled pharmaceutical products that deliver dry powder

drug products to the lung more effectively. 9.11

United Therapeutics,

Cottonwood

Technology Fund, Sun

Mountain Capital,

Undisclosed Investors

HealthVerity 25-Apr-17 Philadelphia, PA Early Stage VC

Provider of healthcare data and patient informatics designed to offer

enhanced data discovery and distribution. 0.10

Flare Capital Partners,

Greycroft Partners,

Foresite Capital Partners

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 4

Page 5: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Forge Therapeutics 25-Apr-17 San Diego, CA Early Stage VC

Developer of antibacterial therapeutics created to treat multi-drug

resistant bacteria. 0.15

SigmaBleyzer, Evotec,

Alexandria Venture

Investments, MP

Healthcare Venture

Management, Red Apple

Group, WS Investments

EpimAb

Biotherapeutics 25-Apr-17

Warmsroth,

Germany Early Stage VC

Provider of biopharmaceutical research and development services

intended to generate novel bi-specific antibody therapeutics. 0.25

Oriza Seed Capital,

Decheng Capital, 3E

Bioventures Capital,

Trend Investment

Group

Doc Halo 25-Apr-17 Cincinnati, OH Later Stage VC

Developer of a clinical communication platform intended to

transform patient care by streamlining real-time communication

among physicians, nurses and staff. 0.11

Bain Capital Ventures,

Refinery Ventures

Dance Biopharm 25-Apr-17 Brisbane, CA

PE Growth/

Expansion

Developer of a pocket-sized inhaler device and insulin container

designed to control prandial blood sugar in adults with diabetes

without the need for injections. 1.46

Aegis Capital Group,

Undisclosed Investors

Circle Pharma 25-Apr-17

South San

Francisco, CA Early Stage VC

Developer of potent, specific and cell-permeable macrocyclic peptides

against important therapeutic targets. 6.50

Mission Bay Capital,

Pfizer Venture

Investments,

ShangPharma

Investment, WI Harper

Group, Elements

Partners, Whitesun

Healthcare Ventures,

LifeForce Ventures and

other undisclosed

investors

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 5

Page 6: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

ChromaCode 25-Apr-17 Carlsbad, CA Early Stage VC

Developer of biotechnological software, reagents and assay products

designed to increase real time PCR instrument's multiplexing. 12.02

New Enterprise

Associates, Domain

Associates and Okapi

Ventures

BluPanda 25-Apr-17 Pittsburgh, PA Angel Provider of robotics management services for the healthcare industry. 2.92 Undisclosed Investors

Babylon Health 25-Apr-17

London, United

Kingdom Early Stage VC

Developer of a digital healthcare consultation application allowing

users to make doctor appointments, access clinical records and

monitor health. 0.60

Hoxton Ventures

Kinnevik and Vostok

New Ventures, Nassef

Sawiris, NNS Holdings,

Undisclosed Investors

Anagin 25-Apr-17 Indianapolis, IN Early Stage VC Developer of a therapy for post traumatic distress syndrome. 3.05 Undisclosed Investors

AltheaDx 25-Apr-17 San Diego, CA Later Stage VC Developer of a pharmacogenetics product testing portfolio. 0.27 Undisclosed Investors

Triggr Health 24-Apr-17 Chicago, IL Early Stage VC

Developer of a predictive system of care designed to help in addiction

recovery with the help of a machine learning algorithm that measures

a person's sleep history, call logs, texting history and general

smartphone usage. 4.20 Drive Capital

Sienna

Biopharmaceuticals 24-Apr-17

Westlake Village,

CA Later Stage VC

Provider of medical dermatology and aesthetics treatment therapies

designed to focus on developing safe and effective targeted therapies

to treat inflammatory skin conditions. 0.40

ARCH Venture

Partners, VenVest

Capital, Partner Fund

Management, Altitude

Life Science Ventures,

David Pyott, Fidelity

Management &

Research

Osteonovus 24-Apr-17 Toledo, OH Angel

Developer of a synthetic bone graft to fill bone gaps and voids in the

skeletal system during orthopedic surgery. 2.50 Undisclosed Investors

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 6

Page 7: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

NanoPharmaceuticals 24-Apr-17 Rensselaer, NY Angel

Developer of pharmaceutical products for a range of health issues,

including macular degeneration, ocular disorders, solid tumors,

hematologic malignancies, arthritis and dermatological conditions. 0.02 Undisclosed Investors

MPIRICA Health 24-Apr-17 Bellevue, WA Early Stage VC

Provider of a cloud-based surgery quality scores platform that enables

patients and payers to avoid surgery risks and costs by directly

connecting patients to high-quality providers. 4.60

OurCrowd, Undisclosed

Investors

KSK Diagnostics 24-Apr-17 Hamburg, Germany Early Stage VC

Developer of molecular point-of-care diagnostic assays designed to

diagnose infectious diseases and cancer. Undisclosed

Innovationsstarter, High

Tech Gründerfonds

SteadyMed Therapeutics

(STDY) 23-Apr-17 San Ramon, CA PIPE

Developer of specialty medical devices designed to deliver injectable

therapeutic drugs. 0.30

Adage Capital

Management, OrbiMed

Deerfield Management,

Kingdon Capital

Management, Ari

Steimatzky, Undisclosed

Investors

SynGen 21-Apr-17 Sacramento, CA Later Stage VC

Developer of single-use disposable cartridges to capture stem and

progenitor cells from peripheral and umbilical cord blood, bone

marrow and adipose tissue. 0.04 Undisclosed Investors

Lyric Pharmaceuticals 21-Apr-17

South San

Francisco, CA Early Stage VC Developer of gastrointestinal therapeutics. 26.79

RiverVest Venture

Partners Sante Ventures,

Third Point Ventures,

Aperture Venture

Partners, Undisclosed

Investors

Healthie 21-Apr-17 Lewes, DE Seed Round

Provider of a cloud-based electronic health records platform for

dietitians. 1.28

Dorm Room Fund,

Undisclosed Investors

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 7

Page 8: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Cellics Therapeutics 21-Apr-17 San Diego, CA Early Stage VC

Developer of nanosponge technology for the treatment of animal

venoms and rare diseases caused by virulent factors attacking red

blood cells. 0.06 Undisclosed Investors

Carmat (ALCAR) 21-Apr-17

Vélizy Villacoublay,

France PIPE

Designer and developer of a bio-compatible, auto-regulated artificial

heart, including right and left ventricles, designed to be as close as

possible to the human heart. Undisclosed Truffle Capital

Biodesix 21-Apr-17 Boulder, CO Later Stage VC

Developer of VeriStrat, a pretreatment serum testing tool that

provides blood-based predictive and prognostic proteomic

information to help physicians guide treatment for patients with non-

small cell lung cancer. 13.17 Undisclosed Investors

AdrenaCard 21-Apr-17 Minneapolis, MN Angel

Designer and developer of a pocket-sized medical device that helps

users inject epinephrine in their legs to control dust, sun and diet

allergies. 1.04 Undisclosed Investors

Abzena (ABZA) 21-Apr-17

Cambridge, United

Kingdom PIPE

Provider of biomedical polymers designed for therapeutic applications

focused on the improvement of protein- and peptide-based drugs. 30.84

Touchstone

Innovations,

Undisclosed Investors

Vesiflo 20-Apr-17 Redmond, WA Angel

Developer of a replaceable urinary prosthesis for female adults with

bladder drainage problems. 2.73 Undisclosed Investors

Recovery Force 20-Apr-17 Fishers, IN

PE Growth/

Expansion

Developer of an active compression and wearable product platform

that enhances the performance and recovery of athletes, consumers,

patients, and military personnel. 1.09 Undisclosed Investors

Mobile Wellness

Solutions MWS 20-Apr-17 Helsinki, Finland Early Stage VC

Developer of a healthcare platform that connects insurance companies

and progressive service providers with its members to facilitate

preventive healthcare services. 1.39 Undisclosed Investors

Microdermics 20-Apr-17 Vancouver, Canada Seed Round

Provider of a novel hollow microneedle delivery platform for the

biopharmaceutical market. 0.01

Entrepreneurship@UBC

Seed Fund K5Ventures,

Shoreline Venture

Management,

Undisclosed Investors

Fresca Medical 20-Apr-17 San Clemente, CA Later Stage VC

Developer of a respiratory device that specializes in the treatment of

patients suffering from obstructive sleeping diseases. 1.80 Undisclosed Investors

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 8

Page 9: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Branchpoint

Technologies 20-Apr-17 Irvine, CA Later Stage VC

Developer of an implantable wireless intracranial pressure monitoring

device. 0.42 Undisclosed Investors

ZappRx 19-Apr-17 Boston, MA Early Stage VC

Provider of an online prescription management platform designed to

modernize, automate and streamline the specialty drug process. 0.25

Qiming Venture

Partners, SR One, GV

Synpromics 19-Apr-17

Edinburgh, United

Kingdom Later Stage VC

Developer of synthetic promoters that are optimally tailored to drive

gene expression at the desired level and specificity, enabling biological

researchers to develop new products with efficacy and safety. 6.41

Scottish Enterprise

Calculus Capital,

Undisclosed Investors

Onkos Surgical 19-Apr-17

Parsippany-Troy

Hills, NJ Early Stage VC

Developer of surgical oncology technologies, including advanced 3D

printing capabilities, limb restoration technologies and biologic

technologies. 17.60

Canaan Partners, 1315

Capital, 3D Systems

Lyndra 19-Apr-17 Watertown, MA Early Stage VC

Developer of a novel therapeutic delivery platform designed to sustain

extended drug release in oral dosage form. 23.08

Polaris Partners, Quark

Venture, GF Securities,

Yonghua Capital,

Healthlink Capital,

Partners Healthcare

Innovation, Suffolk

Equity Partners,

Undisclosed Investors

Delphinus Medical

Technologies 19-Apr-17 Novi, MI Later Stage VC

Developer of a breast ultrasound system designed to differentiate

benign from malignant masses in breast cancer cases. 8.23 Undisclosed Investors

DAMAE Medical 19-Apr-17 Paris, France Early Stage VC

Developer of an in-vivo imaging technology designed to enable

cellular-resolution imaging of the skin similar to histology without the

need for tissue excision and processing. 2.14

Kurma Partners Idinvest

Partners and News

Invest

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 9

Page 10: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

NeuroTronik 18-Apr-17 Durham, NC Early Stage VC

Developer of a therapeutic technology to treat acute heart failure

syndrome. 23.10

Boston Scientific,

Hatteras Venture

Partners, Synergy Life

Science Partners, Lord

Baltimore Capital,

Mountain Group

Partners and Sovereign's

Capital

Mobidiag 18-Apr-17 Espoo, Finland

PE Growth/

Expansion

Developer of diagnostic systems designed to detect gastrointestinal

infections and multi-drug resistant organisms. 4.26

Kansalaisrahoitus,

Undisclosed Investors

Inoviem Scientific 18-Apr-17 Strasbourg, France Later Stage VC

Developer of pre-clinical and clinical technologies designed to

improve lead compound selection and decrease attrition rates during

drug development. 0.80

Capital Grand Est

Bpifrance, Strasbourg

Eurometropole

Cellesce 18-Apr-17

Cardiff, United

Kingdom

PE Growth/

Expansion

Developer of new bio-processing technology intended towards the

growth and expansion of organoids. Undisclosed Finance Wales

CanSino Biologics 18-Apr-17 Tianjin, China Later Stage VC

Developer and manufacturer of vaccine products, including four

novel vaccine candidates against Ebola, tuberculosis, cervical cancer

and pneumococcal infection and new combo vaccines against

meningitis, pertussis, tetanus, diphtheria and Hib. 0.65

SDIC Innovation

Investment

Management, Gopher

Asset, Fortune Venture

Capital, Gold Stone

Investment, Lilly Asia

Venture, Qiming

Venture Partners

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 10

Page 11: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Bonti 18-Apr-17 Newport Beach, CA Early Stage VC

Developer of novel treatments for the treatment of muscle

hyperactivity, the root cause of musculoskeletal pain, in both post-

surgical and non-surgical settings. 11.71

RBV Capital, City Hill

Venture Partners, Hunt

Technology Ventures,

Colt Ventures, JMCR

Partners, HighLight

Capital, Undisclosed

Investors

Actavalon 18-Apr-17 Corona del Mar, CA Angel

Developer of a single, broad spectrum drug designed to target and

eradicate human cancer cells of all types, such as breast, lung,

pancreatic, and colon cancer. 0.03 Undisclosed Investors

VitaHEAT Medical 17-Apr-17

Rolling Meadows,

IL Angel

Provider of a patient warming technology that includes interactive

temperature sensors to actively monitor temperature. 3.69 Undisclosed Investors

RS Research 17-Apr-17 Istanbul, Turkey Early Stage VC

Provider of a novel research platform intended to develop next

generation therapeutics by developing a pioneering class of

nanocarriers that can be used in various proprietary programs in

various stages of preclinical development for the treatment of cancer. 1.28 ACT Venture Partners

Orbis Health Solutions 17-Apr-17 Greenville, SC Angel

Developer of improved methods to stimulate a patient's immune

system and enhance its ability to recognize and destroy disease entities. 0.55 Undisclosed Investors

More Health (mobile

health) 17-Apr-17 Beijing, China Early Stage VC

Developer of a healthcare management platform that integrates data

collection, data analysis, health management and behavioral

intervention into an algorithm called health behavior index that

regulates healthy behavior using a numerical value. 36.30

CITIC Capital Parnters,

Agricultural Bank of

China

Establishment Labs 17-Apr-17 Alajuela, Costa Rica Later Stage VC

Developer of breast and body shaping implants using state-of-the-art

design and manufacturing technologies. 0.18

Kilowatt Capital,

Florence Capital

Advisors

Colorado Therapeutics 17-Apr-17 Broomfield, CO Angel

Developer of xenogenic biologic tissue matrix products and

therapeutic devices for a broad range of soft tissue reinforcement,

regenerative and vascular applications. 2.57 Undisclosed Investors

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 11

Page 12: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

ClariCare 17-Apr-17 Indianapolis, IN Angel Developer of cloud-based dental practice management tools. 0.36 Undisclosed Investors

Zhejiang POCTech

Medical 14-Apr-17 Huzhou, China Later Stage VC

Provider of portable medical monitoring systems consisting of high-

end biosensors to continuously monitor glucose levels. 14.51

Bioventure Investment

Management, Tasly

Great Health Industry

Fund, Tonghua

Dongbao

Pharmaceutical, Legend

Capital

NantCell 14-Apr-17 Culver City, CA Angel

Developer of immunology-based treatments and drugs for the

treatment of cancer and auto-immune diseases. 9.25 Undisclosed Investors

HealthLynked 14-Apr-17 Naples, FL Angel

Provider of a personal electronic medical records system that allows

patients to archive their medical records in coordination with their

physician. 4.02 Undisclosed Investors

Clustermarket 14-Apr-17

London, United

Kingdom Seed Round

Provider of an online marketplace intended to help life scientists list,

discover and book lab space, equipment, expertise and tissues within

their institution or cluster. Undisclosed

London Co Investment

Fund, Undisclosed

Investors

Aspect Imaging 14-Apr-17 Shoham, Israel Angel

Developer of MRI and NMR systems that offer 3D medical imaging

for medical diagnosis and other clinical purposes. 0.30

Stewart Resnick, Eri

Steimatzky

Theraworx 13-Apr-17 Asheville, NC Later Stage VC

Provider of specialty care packs for peri-care prior to foley catheter

insertion and on-going foley maintenance. 34.56 Undisclosed Investors

Sansoro Health 13-Apr-17 Minneapolis, MN Early Stage VC

Developer of Emissary, a reusable, rapidly scalable and secure API

plug-and-play solution for seamless EMR data integration. 5.25

Bain Capital Ventures,

Healthy Ventures,

Treehouse Health,

Undisclosed Investors

ProCheck 13-Apr-17 Karachi, Pakistan Angel Developer of a traceability platform created to authenticate drugs. 0.25 Sarmayacar

Oxford Heartbeat 13-Apr-17

London, United

Kingdom

Accelerator/

Incubator

Developer of a healthcare platform using predictive computations and

AI to help clinicians accurately plan and rehearse stent placements

inside blood vessels. Undisclosed Pitch@Palace

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 12

Page 13: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

M3 Biotechnology 13-Apr-17 Seattle, WA Later Stage VC

Developer of therapeutics and drugs targeting large protein growth

factors for the treatment of neurodegenerative diseases, such as

Alzheimer's, Parkinson's, and ALS. 1.40

Alzheimer's Drug

Discovery Foundation,

Dolby Family Ventures

LIDDS (LIDDS) 13-Apr-17 Uppsala, Sweden PIPE Manufacturer of pharmaceutical products. 0.47 Undisclosed Investor

ILiAD Biotechnologies 13-Apr-17 New York, NY Angel Developer of an improved vaccine to prevent bordetella pertussis. 2.75 Undisclosed Investors

Gel4Med 13-Apr-17 Boston, MA Early Stage VC

Developer of an antimicrobial regenerative tissue scaffolding matrix

designed to prevent postoperative surgical site infections and

complications. Undisclosed Breakout Labs

Envisagenics 13-Apr-17 Huntington, NY Early Stage VC

Developer of a bio-data analysis platform designed to extract

biologically relevant RNA isoforms from raw RNA-seq data, enabling

scientists to detect, quantify and interpret ribonucleic acid sequencing

for reducing drug-development risks. Undisclosed Breakout Labs

EnGeneIC 13-Apr-17 Sydney, Australia Later Stage VC

Developer of a first-in-class, cyto-immunotherapy technology created

to target delivery of chemotherapeutics and functional nucleic acids in

cancer. 0.15 Undisclosed Investors

ClearDATA 13-Apr-17 Austin, TX Later Stage VC

Developer of a healthcare managed cloud platform designed to

safeguard patient's data. 0.12

Merck Global Health

Innovation Fund

Norwest Venture

Partners and Excel

Venture Management,

Heritage Group, HLM

Venture Partners, Flare

Capital Partners

BodyChillz 13-Apr-17

Gatwick, United

Kingdom

Accelerator/

Incubator

Developer, designer and distributor of a non-invasive, unpowered

medical device intended to provide rapid core body cooling to victims

of heatstroke, cardiac arrest and other conditions. Undisclosed Pitch@Palace

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 13

Page 14: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Bioprotect 13-Apr-17 Kfar-Saba, Israel Later Stage VC

Developer of biodegradable balloon systems to protect the rectum

from potential risk of rectal toxicity, enabling patients to undergo

radiation therapy for prostate cancer. 3.50 Undisclosed Investors

Bioniz 13-Apr-17 Irvine, CA Later Stage VC

Developer of small peptides and molecules for treatment of

autoimmune diseases and some forms of cancer. 15.55

Takeda Ventures, David

Pyott, Cota Capital, Joe

Kiani, Undisclosed

Investors

BFKW 13-Apr-17 Grand Rapids, MI Angel

Developer of implanted bariatric devices designed to treat obesity by

inducing long lasting satiety. 2.10 Undisclosed Investors

ALung 13-Apr-17 Pittsburgh, PA Later Stage VC

Provider of advanced medical devices to treat respiratory disorders.

The company engages in the development and sale of intra and extra

corporeal gas exchange device used for the treatment of respiratory

failure. 36.56

Philips and UPMC

Enterprises, Abiomed,

Hermes Group, Allos

Ventures, Birchmere

Ventures, Blue Tree

Ventures, Riverfront

Ventures, Undisclosed

Investors

Adaptive Phage

Therapeutics 13-Apr-17 Bethesda, MD Seed Round

Provider of therapeutics services intended to treat multi-drug resistant

pathogenic bacteria. 0.77 Undisclosed Investors

SYNLAB International 12-Apr-17 Munich, Germany

PE Growth/

Expansion

Provider of medical laboratory services in various diagnostics fields,

including human medical laboratory medicine, human genetics, and

preventive health care. 267.21 Novo Group

Protein Dynamic

Solutions 12-Apr-17 Mayagüez, PR Angel

Provider of clinical trials and biotechnology research and developer of

tools for testing anti-malignant drugs for cancer treatments. 0.02 Undisclosed Investors

HiberGene Diagnostics 12-Apr-17 Dublin, Ireland Later Stage VC

Developer of real-time molecular diagnostic technology designed to

test human infectious diseases. 7.16

Cantor Fitzgerald,

Kernel Capital,

MedCaptain

eXo Systems 12-Apr-17 Oakland, CA Early Stage VC Provider of ultrasound medical imaging technology. 6.05 Undisclosed Investors

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 14

Page 15: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

DesignMedix 12-Apr-17 Portland, OR Later Stage VC

Developer of drugs to combat drug-resistant diseases, such as malaria,

bacterial diseases, sexually transmitted diseases, and other infectious

diseases. 0.65 Undisclosed Investors

Botanix Pharma (BOT) 12-Apr-17 Subiaco, Australia PIPE

Developer of therapeutics for serious skin diseases utilizing synthetic

cannabidiol to improve the lives of patients battling acne, psoriasis and

atopic dermatitis. 4.12 Undisclosed Investors

The Eye Machine 11-Apr-17 Indian Wells, CA Angel

Manufacturer of a medical device that condenses current from direct

current barriers in order to deliver energy around the eye, mitigating

the effects of age-related macular degeneration and diabetic

retinopathy 1.91 Undisclosed Investors

TargEDys 11-Apr-17 Rouen, France Later Stage VC

Developer of hormone mimetic proteins that help in regulating the

eating behavior of obese people. 11.12

Seventure Partners

Pontifax, NCI, Zaluvida,

Bpifrance and NCI

Gestion

Smart Reporting 11-Apr-17 Munich, Germany Early Stage VC

Developer and provider of a structured medical reporting platform

designed to help doctors to increase the quality of their medical

reports. 2.14

Cascara Ventures,

Investment and

Structural Bank of

Rhineland-Palatinate,

Sparkassen-Innovations-

Beteiligungsfinanzierung

sgesellschaft Rheinland-

Pfalz, Undisclosed

Investors

SA Ignite 11-Apr-17 Chicago, IL Later Stage VC

Provider of a cloud-based platform designed to simplify and automate

complex quality reporting, leverage proactive insights to improve

performance, achieve regulatory compliance and satisfy quality

metrics. 2.05 Undisclosed Investors

RC21X 11-Apr-17 Coraopolis, PA

Accelerator/

Incubator

Developer of a web-based measurement and monitoring system

designed to monitor human brain performance. 0.10 Stadia Ventures

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 15

Page 16: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Frequency Therapeutics 11-Apr-17 Woburn, MA Early Stage VC

Developer of small molecule drugs intended to activate progenitor

cells within the body to restore and regenerate sensory cells in the

inner ear to treat chronic noise-induced hearing loss. 0.32

Cobro Ventures,

Alexandria Real Estate

Equities, Emigrant

Capital, Korea

Investment Partners,

Morningside Group

CoreRx 11-Apr-17 Clearwater, FL

PE Growth/

Expansion

Developer and manufacturer of complex oral drugs designed to help

speed the development of drug candidates. 0.05 Undisclosed Investors

BlueprintBio 11-Apr-17 Newport Beach, CA Early Stage VC

Provider of pharmaceutical services that identifies, protects and offers

new biological discoveries to existing clinical, pharmaceutical and

diagnostic companies for personalized medicine treatment. 0.48 Undisclosed Investors

biOasis Technologies

(BTI) 11-Apr-17 Richmond, Canada PIPE

Developer of a platform that delivers therapeutic compounds across

the blood-brain barrier and into the central nervous system for the

treatment of neurological diseases, including brain cancers,

neurodegenerative diseases and metabolic disorders. 3.03 Undisclosed Investors

Synchrony Health 10-Apr-17 Louisville, KY Angel

Provider of healthcare data management and advisory services

intended to build accountable care organizations. 0.10 Undisclosed Investors

Lybrate 10-Apr-17 Faridabad, India Early Stage VC

Developer of an online doctor consultation platform designed to allow

patients access to medical professionals 24 hours a day, 7 days a week,

and help doctors effortlessly manage and grow their practice. 0.03 Undisclosed Investors

ESO Solutions 10-Apr-17 Austin, TX Later Stage VC

Provider of electronic patient care reporting software and billing

services that enable users to share patient data in a bi-directional and

vendor-agnostic environment for fire departments, ambulance billing

operations and others. 0.01

Wild Basin Investments,

Undisclosed Investors

Esanex 10-Apr-17 Indianapolis, IN Later Stage VC

Developer of highly selective and orally active Hsp90 inhibitors for

the treatment of cancer. 2.58 Undisclosed Investors

EnXray 10-Apr-17

Liverpool, United

Kingdom Early Stage VC

Developer of radiation sterilization equipment for generation of low

energy X-rays. 3.86

The North West Fund,

CBC Holdings

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 16

Page 17: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Cirius Therapeutics 10-Apr-17 Kalamazoo, MI Early Stage VC

Developer of an insulin sensitizer designed for the treatment of

nonalcoholic steatohepatitis. 0.40

Frazier Healthcare Novo

A S, Adams Street

Partners, Hopen Life

Science Ventures,

Renaissance Venture

Capital Fund

Geom Therapeutics 8-Apr-17 San Diego, CA Early Stage VC

Developer of novel antibiotics created to provide broad spectrum

coverage including activity against multi-drug resistant Pseudomonas

and Acinetobacter. 4.36

Sears Capital

Management,

Undisclosed Investors

Vasoptic Medical 7-Apr-17 Baltimore, MD Angel

Developer of a portable retinal imager designed to non-invasively

capture physiological information from the retinal microvasculature,

providing a quantitative means of monitoring the progression of

various metrics indicative of ophthalmic and systemic disease. 1.55 Undisclosed Investors

Sonomotion 7-Apr-17 San Francisco, CA Angel

Developer of a non-invasive medical device for kidney stone

treatment. 4.50 Undisclosed Investors

Small Pharma 7-Apr-17

London, United

Kingdom Angel

Developer of antidepressant drugs based on a derivative of ketamine

that can inject antibiotics in limited quantity to activate cerebral

stimulus as per patient's mental and physical fitness. 1.02

Chris Torrance David

Ebsworth Peter Keenn

Steve Harris

SyndicateRoom, Tom

Valentine

OptiNose 7-Apr-17 Yardley, PA Later Stage VC

Developer of exhalation delivery systems that produce high and deep

intranasal deposition of medication. 0.35 Undisclosed Investors

Nanobiotix (NANO) 7-Apr-17 Paris, France PIPE

A nanomedicine company pioneering novel approaches for the local

treatment of cancer by magnifying the effect of radiotherapy within

tumor cells without increasing the dose to surrounding healthy tissues. 26.88

Capital Ventures

International, CM-CIC

Investissement,

Bpifrance, Undisclosed

Investors

MyPostOpCare 7-Apr-17 Huntsville, AL Angel

Developer of an application that offers post-surgery instructions and

guidance to patients to help them in the recovery process. 0.23 Undisclosed Investors

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 17

Page 18: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

ID Genomics 7-Apr-17 Seattle, WA Angel

Developer of a genomics bar-coding-based diagnostic system used to

identify and track drug-resistant human pathogens. 0.68 Undisclosed Investors

Chinova Bioworks 7-Apr-17 Fredericton, Canada

Accelerator/

Incubator

Developer of a antimicrobial chitosan polymer designed to enhance

the shelf-life of medical products, such as cell cultures and liquid

pharmaceuticals. Undisclosed Terra Accelerator

Abpro 7-Apr-17 Woburn, MA Later Stage VC

Provider of protein reagents and services and developer of a discovery

platform for research purposes, such as diagnostics and therapeutics,

that streamlines all aspects of the process to deliver antibodies. 0.10 Undisclosed Investors

Sommetrics 6-Apr-17 Vista, CA Later Stage VC

Developer of medical products and services using proprietary aer+

technology to develop tools for disorders related to the narrowing of

the airway during sleep, such as obstructive sleep apnea and chronic

snoring. 12.30 Undisclosed Investors

Ortho Kinematics 6-Apr-17 Austin, TX Later Stage VC

Provider of a diagnostic test for the spine that uses fluoroscopy to

capture the spine in motion and produces patient-specific graphs that

are uploaded to cloud servers where they are processed to produce

motion measurements for each vertebral level. 20.72

TEXO Ventures Wild

Basin Investments and

Central Texas Angel

Network, Undisclosed

Investors

OM1 6-Apr-17 Cambridge, MA Early Stage VC

Provider of a platform system that gathers, synthesizes, enriches, and

leverages clinical data to provide measurements and AI-driven insights

and predictions that can improve clinical, financial and operational

management. 0.15

General Catalyst

Partners, Glikvest, 7wire

Ventures, Wanxiang

Healthcare Investments

Novita Pharmaceuticals 6-Apr-17 New York, NY Angel Developer of therapeutic drugs for the treatment of cancer. 6.46 Undisclosed Investors

MGB Biopharma 6-Apr-17

Glasgow, United

Kingdom Later Stage VC

Developer of antibiotics intended to offer a new class of anti-infective

medicine. The company's antibiotics offers a new class of small

molecules, with specific antibacterial activity against susceptible and

resistant bacteria, enabling clients to treat bacterial infections through

antibiotics based on Minor Groove Binder (MGBs) compounds. 1.15

Archangel Informal

Investors, TRI Cap,

Barwell and Scottish

Enterprise

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 18

Page 19: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

LB Pharmaceuticals 6-Apr-17 New York, NY Angel Operator of a drug development company. 1.43 Undisclosed Investors

InnerSpace Neuro

Solutions 6-Apr-17 Tustin, CA Angel Developer of an intracranial pressure monitoring technology system. 2.78 Undisclosed Investors

drchrono 6-Apr-17 Mountain View, CA Later Stage VC

Provider of an electronic health record platform designed to offer

patient health insurance verification and medical billing services. 0.14

Runa Capital, Maxfield

Capital, Team in

Residence, SVB Capital,

Box, FundersClub, Eric

Dunn, Bruno Bowden

Darwin Life 6-Apr-17 New York, NY Angel

Developer of an in vitro fertilization technology created to reverse the

effects of age on human oocytes and repair certain cellular defects. 0.01 Undisclosed Investors

Biomarker.io 6-Apr-17 San Francisco, CA

Accelerator/

Incubator

Developer of an online health platform designed to track and decode

impact of dietary changes on health and performance. Undisclosed Terra Accelerator

Alliance Growers

(ACG) 6-Apr-17 Vancouver, Canada PIPE Producer of medical marijuana. 0.05 Alumina Partners

HealthFeed (Velocitos) 5-Apr-17 Sunnyvale, CA Angel

Provider of an automated content delivery platform designed for

healthcare patients and members. 0.01 Undisclosed Investors

Contraline 5-Apr-17 Charlottesville, VA Seed Round

Developer of non-hormonal, non-surgical and reversible male

contraceptive technology. 2.50

Founders Fund,

Abstract Ventures,

Jaffray Woodriff, Center

for Innovative

Technology, Jason

Calacanis, Afton

Scientific

Axial3D 5-Apr-17

Belfast, United

Kingdom Seed Round

Developer of a patient-specific 3D printed model designed to better

understand a patient's unique pathology and deliver personalized

anatomical insights. 0.65

Techstart NI, Patrick

Hurst, Undisclosed

Investors

Acera 5-Apr-17 Owings, MD Angel

Manufacturer of endoscopic brushes designed to fill unmet needs in

the field of gastrointestinal endoscopy. 0.03 Undisclosed Investors

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 19

Page 20: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Viracta Therapeutics 4-Apr-17 San Diego, CA Later Stage VC

Operator of a clinical-stage drug development company intended to

develop medicines to treat virus-associated cancers. 18.40

NantKwest, Wicklow

Capital, Latterell

Venture Partners,

Forward Ventures

Synchron 4-Apr-17 Campbell, CA Later Stage VC

Developer of a minimally invasive implantable device designed to

interpret signals from the brain for the treatment of brain pathologies,

such as paralysis, epilepsy and movement disorders. 0.10

NeuroTechnology

Investors, Defense

Advanced Research

Projects Agency, United

States Department of

Defense

Sentien Biotechnologies 4-Apr-17 Lexington, MA Later Stage VC

Developer of new blood conditioning therapies harnessing the power

of cell therapy with innovative drug delivery systems designed to

restore balance to the immune system of critically ill patients. 0.12

Boehringer Ingelheim

Venture Fund,

BioInnovation, Chiesi

Ventures, MBL Venture

Capital, Mass Medical

Angels

Prevent Biometrics 4-Apr-17 Minneapolis, MN Early Stage VC

Developer of a real-time head impact monitoring system designed to

record the force, location and direction of head impact, enabling

coaches, trainers and parents to instantly know when an athlete is hit

hard enough to cause a concussion. 3.80 Undisclosed Investors

PEC360 4-Apr-17

North Charleston,

SC Later Stage VC

Provider of a patient management platform designed to proactively

identify, manage and schedule patients with healthcare needs. 0.20

SCRA Technology

Ventures

Nova Satra Diagnostics 4-Apr-17

Singapore,

Singapore Angel

Developer of blood-based diagnostic tests that leverage epigenetic

platform technology for testing breast cancer using stable DNA-based

targets as part of chromosomal signatures to allow healthcare

providers to accurately diagnose and detect cancer at earlier stages. 1.99 Genting Bio Cellular

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 20

Page 21: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Neural Analytics 4-Apr-17 Los Angeles, CA Early Stage VC

Manufacturer of medical devices for measuring intracranial pressure

designed to accurately assess mild to traumatic brain injury, including

concussions. 10.15

Reimagined Ventures,

Undisclosed Investors

Micell Technologies 4-Apr-17 Durham, NC Later Stage VC

Developer of drug-delivery systems for cardiovascular diseases

designed to limit the duration of polymer exposure, optimize healing,

more precisely and consistently control drug elution, and improve

safety and clinical outcomes. 31.78 Undisclosed Investors

Lakewood-Amedex 4-Apr-17 Sarasota, FL Angel

Developer of an oligonucleotide gene-silencing platform designed to

treat infectious diseases, such as hepatitis B and C, pandemic viral

infections and avian influenza. 2.90 Undisclosed Investors

Innovative

Cardiovascular

Solutions 4-Apr-17 Grand Rapids, MI Angel

Developer of an embolic protection catheter that has been designed to

be utilized in trans aortic valve replacement procedures and other left

heart interventional procedures. 3.09 Undisclosed Investors

GLG Pharma (GLG) 4-Apr-17 Wroclaw, Poland PIPE

Developer of advanced cancer therapy techniques based on STAT3

protein for the treatment of tumors, lung cancer, leukemia and other

hyperproliferative diseases. Undisclosed

Apollo Global

Management

Deutsche Arzt 4-Apr-17 Essen, Germany Early Stage VC

Developer of an e-health platform designed to connect doctors,

patients, physiotherapists and health insurance funds online. Undisclosed

NRW.Bank, Optadata,

Novinvest

AbCellera 4-Apr-17 Vancouver, Canada Later Stage VC

Developer of a microfluidic single-cell platform that screens millions

of immune cells in a single day, increasing the speed and efficiency of

monoclonal antibody discovery with the potential to accelerate the

development of urgently needed diagnostic tests and vaccines. 0.82 Undisclosed Investors

Transplant Genomics 3-Apr-17 Mansfield, MA Early Stage VC

Developer of molecular diagnostic tests to improve organ transplant

outcomes with non-invasive serial monitoring guided by genomics. 8.05 Undisclosed Investors

The Progressive

Orthopaedic Company 3-Apr-17

North Palm Beach,

FL

PE Growth/

Expansion

Manufacturer and distributor of low-cost orthopaedic implants and

medical devices. Undisclosed IBS Investment Bank

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 21

Page 22: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Simple Contacts 3-Apr-17 New York, NY Early Stage VC

Developer of a mobile application designed to test and renew eyewear

prescriptions. 0.08

Goodwater Capital,

Justin Kan, Notation

Capital, Autonomous

Ventures, Steven Cohen,

Undisclosed Investors

RxSight 3-Apr-17 Aliso Viejo, CA Later Stage VC

Developer of adjustable intraocular technology designed to empower

the global cataract market and transform cataract surgery from a

purely predictive method to a dynamic prescription process. 48.98 Undisclosed Investors

Redox 3-Apr-17 Madison, WI Early Stage VC

Provider of an information technology platform designed to eradicate

technical barriers in healthcare systems. The company's information

technology platform can be integrated with EHRs and health systems

enabling digital healthcare enterprises to manage their connections in

the cloud. 0.10

RRE Ventures, .406

Ventures, Flybridge

Capital Partners,

Dreamit Ventures,

HealthX Ventures,

Intermountain

Healthcare

Opthea (OPT) 3-Apr-17

South Yarra,

Australia PIPE

Developer of novel biologic therapies to block vascular growth factors

that cause blood vessels to leak and lead to eye diseases. 32.01 Undisclosed Investors

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 22

Page 23: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Company Name

Last

Financing

Date

HQ Location Round Description

Last

Financing

Size

(Millions)

Investor(s)

Private Equity Placements and Venture Capital RoundsThe following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced

over the previous month.

Intarcia Therapeutics 3-Apr-17 Boston, MA Later Stage VC

Developer of therapeutic products to enhance treatment outcomes by

optimizing and improving the efficacy, continuous administration and

tolerability of drug therapies. 475.68

Kayon Partners, Baillie

Gifford, Bill & Melinda

Gates Foundation,

Luxin Venture Capital,

Fidelity Investments, RA

Capital Management,

Foresite Capital

Management, The

Pritzker Organization,

The Baupost Group,

Undisclosed Investors

Chartfill 3-Apr-17 Victor, NY Angel

Provider of a clinical data analytics platform designed to streamline

care transitions and enhance patient satisfaction. 0.23 Undisclosed Investors

Analytics 4 Life 3-Apr-17 Kingston, Canada Angel

Developer of a cardiac monitoring device using advanced signal

processing techniques and machine-learned algorithms to reveal

previously hidden information about a patient's health status from

within their physiological signals in the coronary artery. 4.09 Undisclosed Investors

HUMM Technologies 2-Apr-17 Perth, Australia

Accelerator/

Incubator

Developer of a neurotechnology product that allows to see the

workings of the brain, guides in behavioral changes, and harnesses

recent advances in machine learning, cloud processing and wearable

technology, supplementing human intelligence with artificial

intelligence. 0.03 Plus Eight Accelerator

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 23

Page 24: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Acquirer Target HQ Location Date DescriptionTransaction

Value (Millions)

Allergan Zeltiq Aesthetics Pleasanton, CA 28-Apr-17

Developer of a non-surgical fat reduction treatment that uses controlled cooling

to eliminate fat without affecting surrounding tissue. 24.80

Numotion

Horn's Medical

Supply Athens, TX 28-Apr-17

Developer of power wheelchairs, pediatric equipment, beds and accessories,

oxygen therapy and other mobility products. Undisclosed

Savara Pharmaceuticals Mast Therapeutics San Diego, CA 27-Apr-17

Developer of novel, clinical-stage therapies for respiratory diseases, sickle cell, rare

genetic disorders, and heart failure. 1.65

DocuTap Clockwise.MD Atlanta, GA 27-Apr-17 Provider of online self-scheduling and queue management services. Undisclosed

Surgical Information

Systems

Source Medical

Solutions Birmingham, AL 25-Apr-17 Provider of ambulatory surgery center software and services. Undisclosed

Belluscura

Nanotether

Discovery Science

Cardiff, United

Kingdom 25-Apr-17

Developer of high throughput quantitative binding assays that utilize variable

length DNA molecules as tethers for binding pairs of test molecules in close

proximity, thereby miniaturising biological assays and vastly reducing the quantity

of materials required compared with current technologies. 0.33

Norgesplaster ScanSport Vennesla, Norway 24-Apr-17 Manufacturer of sports injury prevention equipment. Undisclosed

Perspective

Technologies Nanosensors Redwood City, CA 21-Apr-17

Manufacturer of sensors and semiconductor components created to detect

specified levels of targeted specific biological, chemical and explosive agents. Undisclosed

Beaver Visitec

International Malosa Medical

Halifax, United

Kingdom 21-Apr-17

Manufacturer and supplier of single-use surgical instruments for use in some of

the most frequently performed procedures, including cataract surgery and

intravitreal injection. Undisclosed

Underwriters

Laboratories Emergo Group Austin, TX 21-Apr-17

Provider of regulatory and market access services, including medical device

registration and approval, regulatory strategy, and ISO 13485 and QMS

compliance. Undisclosed

Veritas Pharma

Cannevert

Therapeutics Vancouver, Canada 21-Apr-17

Provider of cannabis strains intended to shed light on the medical potential of

cannabis by establishing a sound scientific basis for its therapeutic use research. 1.50

Protek Rafarma antibiotics Moscow, Russia 20-Apr-17

Producer and distributor of antibodies, pharmaceutical substances, anti-tumor

drugs, anti-TB drugs and other pharmaceutical related drugs. 1.00

Mergers and AcquisitionsThe following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous

month.

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 24

Page 25: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Acquirer Target HQ Location Date DescriptionTransaction

Value (Millions)

Mergers and AcquisitionsThe following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous

month.

Avantor Performance

Materials Puritan Products Bethlehem, PA 20-Apr-17

Manufacturer of chemicals and custom-blended formulations intended to be used

in pharmaceutical, biotechnology, microelectronic and laboratory markets. Undisclosed

Vyaire Medical Ciel Medical San Carlos, CA 20-Apr-17 Developer of a medical device intended to treat ventilator-associated pneumonia. Undisclosed

Diploma Abacus ALS Waterford, Australia 20-Apr-17

Distributor of in vitro diagnostic products, diagnostic pathology products,

healthcare educational supplies, innovative laboratory equipment and other

diagnostics instrumentation and consumables. 11.97

PLx Pharma

Dipexium

Pharmaceuticals New York, NY 19-Apr-17

Developer of pharmaceutical products for the treatment of certain mild and

moderate skin infections in superficial wounds. Undisclosed

Heidelberg Engineering

Medisoft (Medical

Records Systems)

Leeds, United

Kingdom 18-Apr-17 Developer of electronic medical records software for the ophthalmic market. Undisclosed

Hms Holdings Eliza Danvers, MA 18-Apr-17

Designer of an integrated healthcare communication and management software

using cloud technology, advanced proprietary predictive analytics, behavioral

science and data driven design methodologies to personalize outreach. 1.72

Ciox Health ArroHealth Hauppauge, NY 18-Apr-17

Provider of analytics, medical record retrieval, data aggregation and risk

adjustment coding to accurately represent the impact of risk adjustment and

HEDIS programs and improve insights into quality metrics. Undisclosed

NextGen Healthcare

Information Systems Entrada Brentwood, TN 14-Apr-17

Developer of software for the automation of clinical documentation and data

exchanges in ambulatory clinics, surgery centers and hospitals. 0.34

Amendia Spinal Elements Carlsbad, CA 13-Apr-17

Designer and developer of spinal surgical devices designed to advance the

performance of spinal implants and instruments. Undisclosed

NantOmics Genos Research San Francisco, CA 13-Apr-17

Provider of a genomics research and discovery platform intended to accelerate

disease research and medical cures. Undisclosed

Relias Learning

Care Management

Technologies Morrisville, NC 13-Apr-17

Operator of a population health management company with deep expertise in

behavioral health data analytics intended to deliver actionable information to

clinicians at the point of treatment to improve quality of care and reduce costs. Undisclosed

Group Doehler HIS (France) Lyon, France 12-Apr-17

Provider of health ingredients for the dietary supplement, food and beverage,

nutrition, cosmetic and pharmaceutical industries. Undisclosed

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 25

Page 26: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Acquirer Target HQ Location Date DescriptionTransaction

Value (Millions)

Mergers and AcquisitionsThe following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous

month.

Exova SL Pharma Labs Wilmington, DE 11-Apr-17

Provider of parenteral, liquid and topical drug products including formulation

development, analytical development, microbiological development and early stage

clinical manufacturing. Undisclosed

Anju Software OpenQ Charlottesville, VA 11-Apr-17

Developer of software applications that combine big data and expert validation to

deliver actionable information that mitigates compliance risks. Undisclosed

MYM Nutraceuticals HempMed Toronto, Canada 11-Apr-17

Developer and marketer of Hemp CBD extract and oil infused nutraceutical

products. 0.01

GE Healthcare Asymptote

Cambridge, United

Kingdom 11-Apr-17

Developer of cryochain technology designed to maintain the potency of cellular

therapies by enabling ultra-low temperature freezing during production all the way

to thawing at the clinic prior to administering to patients.. Undisclosed

Alexander Zharkov TNK Silm Moscow, Russia 10-Apr-17

Developer of silicone compound-based drugs for atopic dermatitis, psoriasis,

diarrhea of various origins, food poisoning, hangovers, eczema, and acne. Undisclosed

DePuy Synthes Neuravi Galway, Ireland 10-Apr-17

Developer of innovative medical devices designed for neurointerventional

therapies. Undisclosed

PetVivo

Gel-Del

Technologies Saint Paul, MN 10-Apr-17

Manufacturer of bio-material devices, including cosmetic tissue fillers, blood

vessel grafts, implanted oral and drug delivery systems. 0.40

Mr Rene Lauritsen

Alterola Biotech

(nutraceutrical

chewing gum

business) Walnut, CA 10-Apr-17

Manufacturer of nutraceutrical chewing gum used as an appetite and cholesterol

suppressor, as well as for motion sickness control. Undisclosed

Jordan Industries

International

Transtate

Equipment

Company Charlotte, NC 7-Apr-17

Provider of refurbished catheter angiography equipment along with on-site

services. Undisclosed

VWR International Mesm

Chorley, United

Kingdom 7-Apr-17

Manufacturer and supplier of laboratory and medical equipment and ancillary

supplies, including analyzers, spirometers, freezers, measuring devices and

infusion and syringe pumps. Undisclosed

Alpha Source Medical Optics Tamarac, FL 7-Apr-17

Provider of a medical instrument repair management tool designed to repair and

keep records of medical equipment. Undisclosed

Grünenthal Adhesys Medical Aachen, Germany 7-Apr-17

Developer and manufacturer of next generation surgical adhesives created to

bring novel surgical sealants to physicians. Undisclosed

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 26

Page 27: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Acquirer Target HQ Location Date DescriptionTransaction

Value (Millions)

Mergers and AcquisitionsThe following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous

month.

Valens GroWorks Supra Thc Services Kelowna, Canada 6-Apr-17

Provider of microbial screening, analysis, testing and development for medical

marijuana. 3.75

Touchstone

Innovations

Cardian

(Monitoring

Equipment)

London, United

Kingdom 6-Apr-17

Provider of wireless pulmonary arterial pressure sensor device intended to

improve the monitoring and treatment of cardiac failure patients. 1.85

Medical Imaging

Partnership

Medical Imaging

London

London, United

Kingdom 5-Apr-17 Provider of diagnostic imaging and reporting services. Undisclosed

Cannabis Science Jinvator BioMed

Bad Honnef,

Germany 5-Apr-17 Developer of a rapid HIV/AIDS test. Undisclosed

Porvair

J. G. Finneran

Associates Vineland, NJ 5-Apr-17

Manufacturer and distributor of specialist laboratory products intended to offer

custom designed machinery and accessories, including filters, vials, microplates,

closures and ancillary products. 0.14

iHealth Innovations emPower Docs New York, NY 5-Apr-17

Provider of healthcare software products and related services to large independent

practices that specialize in vascular surgery, cardiology, orthopedics, and several

primary care specialties. Undisclosed

Concordance

Healthcare Solutions

Rockwell Medical

Supply Seal Beach, CA 4-Apr-17

Supplier of medical products, including cotton balls, exam tables, diagnostic lights,

tongue depressors, ECG equipment, spirometry equipment and disposable items. Undisclosed

Mitchell International PMOA Mobile, AL 4-Apr-17

Operator of a pharmacy benefit management company created to offer simplified

cost-control services. Undisclosed

Teletech Holdings Connextions Orlando, FL 4-Apr-17

Developer of a proprietary technology-enabled services platform designed to offer

member acquisition, retention and engagement services. 0.80

CareFusion

Caesarea Medical

Electronics Caesarea, Israel 4-Apr-17

Manufacturer of medical infusion and syringe pump systems designed to offer

project level customization including specialist disposables, software language

adaptation and other treatment solving services. Undisclosed

Sucampo

Pharmaceuticals Vtesse Gaithersburg, MD 3-Apr-17

Developer of new drug treatments designed to treat severe and life-threatening

lysosomal storage diseases. 2.00

Wellpass Voxiva Arlington, VA 3-Apr-17

Provider of an online member engagement platform created to communicate

about health programs. Undisclosed

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 27

Page 28: Monthly Healthcare Review April 2017 - BioEnterprise...ABG Sundal Collier ASA, Arctic Securities, DNB Markets The following table includes the medical devices, biotechnology, pharmaceuticals,

Monthly Healthcare Review

April 2017

Acquirer Target HQ Location Date DescriptionTransaction

Value (Millions)

Mergers and AcquisitionsThe following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous

month.

Nordson

Vention Medical

(Advanced

Technologies

Business) Salem, NH 3-Apr-17

Designer, developer and manufacturer of minimally invasive interventional

delivery devices, catheters and advanced components. 7.05

Aurora Diagnostics

University

Pathologists Warwick, RI 3-Apr-17 Provider of hospital-based professional anatomic pathology services. Undisclosed

Mr Ian Aaron and other

undisclosed investors UK Medical

Sheffield, United

Kingdom 3-Apr-17

Supplier of interventional medical devices used in minimally-invasive image-

guided procedures to diagnose and treat diseases in various organs of the body,

with a particular focus on devices used in breast radiology, urology, interventional

radiology and cardiology. Undisclosed

Teleflex Pyng Medical Richmond, Canada 3-Apr-17

Developer of medical technology for critical-care environments created to

commercialize trauma and resuscitation products. 8.60

Castlight Health Jiff Mountain View, CA 3-Apr-17 Developer of a cloud-based application platform to manage patients. Undisclosed

Dynatronics

Hausmann

Industries Northvale, NJ 3-Apr-17

Manufacturer of a full range of laminate treatment tables, stools, benches and

cabinets along with medical, therapy and athletic training equipment. 0.10

McKesson

GMD

PharmaSolutions Oakville, Canada 3-Apr-17

Provider of pharmaceutical logistic services intended to offer direct distribution

and point-of-care administration of specialty pharmaceuticals. Undisclosed

Sartorius Essen BioScience Ann Arbor, MI 3-Apr-17

Developer and manufacturer of instruments, software, reagents and consumables

that allow researchers to remotely image and quantitate a wide variety of cellular

processes over time. 3.20

Svenska Cellulosa

Aktiebolaget BSN medical Luxembourg 3-Apr-17

Provider of casting, bandaging, and compression stockings for wound care and

vascular diseases. 1496.40

Sirius International

Insurance Group ArmadaGlobal Hunt Valley, MD 3-Apr-17

Provider of employee benefit consulting services created to fill the growing

financial and accessibility gaps in the healthcare system. Undisclosed

Wellpartner

340B SMART

Solutions Memphis, TN 3-Apr-17 Provider of split-billing and retail pharmacy gateway software. Undisclosed

The Carlyle Group WellDyneRx Lakeland, FL 1-Apr-17

Provider full-service prescription drug management between patients and drug

plans through a network of retail providers in addition to a mail order and

specialty drug pharmacy. Undisclosed

Compiled by: Lea Keller and Morgan Reape

Source: Pitchbook 28