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MINISTRY OF HEALTH OF UKRAINE

BOGOMOLETS NATIONAL MEDICAL UNIVERSITY

"Pediatrics, children's infectious diseases"

WORKING PROGRAM FOR DISCIPLINE STUDY

Educational qualification: Master of Medicine

Field of knowledge: 22 «Health care»

Specialty: 222 Medicine

Qualification professional: "Doctor"

Kyiv 2020

___ «APPROVED»

Vice-rector on educational work

Professor Vlasenko O.M.

Recommended

At the methodical meeting of the

Department of Pediatrics No. 4

Head of the Department, Academician

of the National Academy of Medical

Sciences of Ukraine

Professor________________________

______

V.G. Maidannyk

«31» 08 2020

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STRUCTURE OF THE WORKING EDUCATION PROGRAM

PROFESSIONAL PEDIATRICS DISCIPLINE

AUTHORSHIP

Head of the Department - Doctor of Medical Sciences, MD, PhD, Academician of the NAMS of

Ukraine Professor V.G. Maidannyk; MD, PhD Professor V.G. Burlay; MD, PhD, Associate

Professor Ie.A. Burlaka; MD, PhD, Associate Professor R.V. Terletskiy; MD, PhD, Associate

Professor G.V. Saltykova; MD, PhD, Associate Professor S.Yu. Svoikina; MD, PhD Assistant

T.D. Klets; MD, PhD Assistant T.A. Shevchenko.

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1. Description of the discipline

"Pediatrics, children's infectious diseases"

Name of indicators

Field of knowledge, direction

of training, educational and

qualification level

Characteristics of the

discipline

full-time education

Number of credits – 5

Branch of knowledge

1201. Medicine

(code and name)

Normative

Training direction

1201. Medicine

(code and name)

Modules – 2

Specialty:

7.12010001

"Medical business".

Year of preparation

5th Content modules – 4

Individual research task:

educational history

Semester

ІХ - Х The total number of hours

is 150 Lectures

10 hours

Education level:

IV

Practical

80 hours.

Laboratory

0 hours.

Independent work

60 hours.

Type of control:

FC

Note.

The ratio of the number of hours of classroom classes to independent and individual work is (%):

2:1

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The working program of the discipline "Pediatrics, children's infectious diseases" is made

according to educational and qualification characteristics (EQC) and educational and professional

programs (EPP) training of specialists in the field of knowledge 22 "Health", specialty 222

"Medicine", educational qualification level "Master", professional qualification "Doctor" for

approved by the order of the Ministry of Education and Science of Ukraine from 06.11.2015

№1151 "On the peculiarities of the list of knowledge and specialties for which higher education

students are trained ”approved by the Resolution of the Cabinet of Ministers of Ukraine of April

29, 2015 under №266. methodological recommendations for the development of standards of

higher education, approved by the order of the Ministry of Education and Science of Ukraine from

01.06.2016 №600 "On approval of recommendations for the development of standards of higher

education" with changes and additions made by the order of the Ministry of Education and Science

of Ukraine from 21.12.2017 for №1648. instructions on the system of assessment of students'

educational activity in the conditions of implementation of the European credit-transfer system of

organization of the educational process, approved by the Ministry of Health of Ukraine 15.04.2014

"Regulations on the organization of the educational process at Bogomolets National

Medical University” approved by the order №4604 NMU, dated July 26, 2017;

"Regulations on the procedure for assessing students' knowledge during the current and

final control of the discipline at Bogomolets National Medical University approved by order №1

of September 5, 2019.

The subject of study of the discipline "Pediatrics, pediatric infectious diseases" are the most

common diseases of newborns, non-communicable diseases of childhood (endocrine diseases and

diseases of the blood system in children) and the most common infectious diseases of children.

Interdisciplinary links: according to the curriculum, the study of the discipline "Pediatrics,

Pediatric Infectious Diseases" provided in the IX - X semesters. Prior to that, the student acquired

relevant knowledge in the main basic disciplines: medical biology, normal anatomy, normal

physiology, histology and embryology, bioorganic and biological chemistry, microbiology and

virology and immunology, pathomorphology, pathophysiology, pharmacology, and clinical

disciplines: propaetriadic, pediatric therapy, surgery, obstetrics with which the program of the

discipline "Pediatrics, pediatric infectious diseases" is integrated. In turn, the discipline

"Pediatrics, Pediatric Infectious Diseases" forms the basis for further study by the student of the

discipline "Pediatrics with Pediatric Infectious Diseases", "General Practice (Family Medicine)",

which provides integration with these disciplines "vertically" and skills for further training and

application in professional activities.

The curriculum of the discipline "Pediatrics, Pediatric Infectious Diseases" consists of the

following modules:

Module 1. Neonatology, diseases of the blood and endocrine system in children.

Module 2. Children's infectious diseases

The organization of the educational process is carried out according to the requirements of

the European credit transfer system.

1. The purpose of the discipline

"Pediatrics, children's infectious diseases"

1.1. The purpose of teaching the discipline "Pediatrics, pediatric infectious

diseases" is to provide students with knowledge and professional skills in neonatology,

pediatric endocrinology, pediatric hematology and pediatric infectious diseases based on

knowledge of age anatomical and physiological features of the child's body, medical

biology, normal anatomy, normal physiology histology and embryology, biochemistry,

microbiology and virology, pathomorphology, pathophysiology, pharmacology and skills

of clinical, laboratory and instrumental examination of the child in compliance with the

principles of medical ethics and deontology.

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1.2. The main tasks of studying the discipline "Pediatrics, children's infectious diseases"

are:

- Assimilation of basic theoretical knowledge of etiology, pathogenesis, clinical

manifestations, data of laboratory and instrumental research methods, treatment,

prevention and prognosis of the most common diseases of infants, children with endocrine,

hematological diseases, pediatric infectious diseases.

- Mastering the basic practical skills and abilities in diagnosis, differential

diagnosis, treatment and emergency care for the most common diseases of infants, children

with endocrine, hematological diseases and childhood infectious diseases.

- Formation of students' moral, ethical and deontological qualities in professional

communication with a sick child and persons caring for a child.

1.3. Competences and learning outcomes

According to the requirements of the standard of the discipline, provides students with the

acquisition of competencies:

- integrated competencies: the ability to solve typical and complex specialized problems

and practical problems in professional activities in the field of health care, or in the learning

process, which involves research and / or innovation and is characterized by complexity and

uncertainty of conditions and requirements

- general competencies:

- ability to abstract thinking, analysis and synthesis.

- ability to apply knowledge in practical situations

- knowledge and understanding of the subject area and understanding of professional

activity

- ability to communicate in the state language both orally and in writing, ability to

communicate in a foreign language

- skills of using information and communication technologies

- ability to search, process and analyze information from various sources

- ability to be critical and self-critical

- ability to adapt, and creativity

- certainty and persistence in relation to the tasks

- ability to make informed decisions, work in a team

- ability to act socially responsibly and consciously.

Special (professional) competencies:

Know:

- definition, prevalence, classification, etiology and pathogenesis of the most common

diseases of infants, children with endocrine, hematological diseases and childhood infectious

diseases;

- clinical manifestations in the uncomplicated and complicated course of the most common

diseases of newborns, children with endocrine, hematological diseases and childhood infectious

diseases;

- criteria for establishing a preliminary clinical diagnosis in the most common diseases of

newborns, children with endocrine, hematological diseases and childhood infectious diseases;

- plan of laboratory and instrumental examination of children with the most common

diseases of infants, children with endocrine, hematological diseases and children's infectious

diseases;

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- differential diagnosis of the most common diseases of infants, children with endocrine,

hematological diseases and childhood infectious diseases;

- criteria for establishing the final clinical diagnosis of the most common diseases of

infants, children with endocrine, hematological diseases and childhood infectious diseases;

- treatment of the most common diseases of infants, children with endocrine, hematological

diseases and childhood infectious diseases;

- protocol of first aid for the most common diseases of infants, children with endocrine,

hematological diseases and infectious diseases of children;

- prevention of the most common diseases of newborns, children with endocrine,

hematological diseases and childhood infectious diseases. Organization of anti-epidemic measures

in the center of the most common infectious diseases in children. Calendar of preventive

vaccinations;

- prognosis for the most common diseases of infants, children with endocrine,

hematological diseases and childhood infectious diseases;

- basic principles of medical ethics and deontology in professional communication with a

sick child and persons caring for a child.

be able:

- to determine the etiology and pathogenetic factors of neonatal diseases and the most

common childhood non-communicable diseases (PP.101);

- to determine the features of diseases of newborns and to make a preliminary clinical

diagnosis (PP.119);

- to determine various clinical variants and complications of the most common diseases of

childhood (PP.123);

- to determine the tactics of the patient with the most common diseases of childhood

(PP.132);

- demonstrate mastery of the principles of treatment, rehabilitation and prevention of

diseases of newborns and the most common children's non-communicable diseases (PP.157);

- to demonstrate the ability to maintain medical records in the clinic of children's diseases

(PP.159);

- plan examinations and interpret laboratory data in the typical course of diseases of

newborns and the most common children's non-communicable diseases (PP.220);

- to demonstrate mastery of moral and deontological principles of a medical specialist and

the principles of professional subordination in a pediatric clinic (PP.173);

- to carry out differential diagnosis and to make the preliminary diagnosis of diseases of

newborns and the most widespread children's noninfectious diseases (PP.230);

- diagnose and provide emergency care for major emergencies in newborns and children

with the most common non-communicable diseases (PP.251);

- to make a life forecast for the most common somatic diseases of childhood (PP.198);

- to determine the etiological and pathogenetic factors of the most common infectious

diseases of children (PP 021);

- to distinguish the features of the clinical course of the most common infectious diseases

of children (PP 039);

- make a preliminary diagnosis of the most common infectious diseases of children (PP

043);

- to determine the tactics of the child suffering from the most common infectious diseases

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(PP 052);

- to determine the main directions of treatment of the most common infectious diseases in

children (PP 022);

- to determine preventive and anti-epidemic measures for the most common infectious

diseases of children (PP 023).

The study discipline "Pediatrics, Pediatric Infectious Diseases" is given 150 hours - 5 ECTS

credits, 90 hours of which is classroom training (in the form of lectures - 10 hours and practical

classes - 80 hours) and 60 hours - independent work of students.

Curriculum

"Pediatrics, children's infectious diseases"

MODULE 1. Neonatology, diseases of the blood and endocrine system in children

CONTENT MODULE 1. Neonatology

Topic 1. Organization of neonatal care in Ukraine. Medical care for a healthy newborn

baby.

Organization of neonatal care in Ukraine. Medical care for a healthy newborn baby. Issues

of bioethics in modern neonatology Premature babies. Children with intrauterine growth

retardation.

Criteria for determining prematurity. Features of adaptation of premature babies.

Etiological factors of prematurity. Anatomical and physiological features. Classification of

premature infants by birth weight and the ratio of physical development and gestational age.

Assessment of morphological and neuro-functional maturity of premature infants (Ballard scale).

Principles of nursing premature babies. Features of breastfeeding premature babies. Emergency

care for major emergencies in premature infants: hypothermia, respiratory failure, hypoglycemia.

Intrauterine growth retardation: causes, postnatal diagnosis, features of early neonatal adaptation.

Topic 2.

Topic 1. Asphyxia of the newborn. Cardiopulmonary resuscitation of newborns.

Neonatal asphyxia: etiology, pathogenesis, classification, clinic, diagnosis, differential

diagnosis, treatment, prevention, prognosis. Primary resuscitation of newborns.

Childbirth trauma: etiology, pathogenesis, classification, clinic, diagnosis, differential

diagnosis, treatment, prevention, prognosis.

Topic 2. Neonatal respiratory distress syndrome (RDS). Neonatal pneumonia.

Respiratory distress syndrome of newborns: etiology, pathogenesis, classification, clinic,

diagnosis, differential diagnosis, treatment, prevention, prognosis.

Neonatal pneumonia: etiology, pathogenesis, classification, clinic, diagnosis, differential

diagnosis, treatment, prevention, prognosis.

Topic 3. Hemolytic disease of the newborn (GHN). Differential diagnosis of jaundice in

newborns

Hemolytic disease of newborns: etiology, pathogenesis, classification, clinic, diagnosis,

differential diagnosis, treatment, prevention, prognosis.

Hemorrhagic disease of newborns: etiology, pathogenesis, classification, clinic, diagnosis,

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differential diagnosis, treatment, prevention, prognosis.

Topic 4. Bacterial infections of newborns. (TORCH - infections).

Purulent-inflammatory diseases of the skin and subcutaneous fat of newborns, diseases of

the umbilical cord, umbilical wound and umbilical vessels: classification, etiology, pathogenesis,

clinic, diagnosis, differential diagnosis, treatment, prevention, prognosis. Neonatal sepsis:

definition, classification, etiology, pathogenesis, clinic, diagnosis, differential diagnosis,

treatment, prevention, prognosis.

CONTENT MODULE 2. Diseases of the blood system in children

Topic 5. Anemia in children (deficient, posthemorrhagic, aplastic).

Anemia in children (deficient, posthemorrhagic, hemolytic, due to hematopoietic

disorders): definition, etiology, pathogenesis, classification, clinic, diagnosis, differential

diagnosis, treatment, prevention, prognosis.

Topic 6. Hemorrhagic diseases in children. Coagulopathies (hemophilia): in children:

etiology, pathogenesis, classification, clinic, diagnosis, differential diagnosis, treatment,

prevention, prognosis. Thrombocytopenia (thrombocytopenic idiopathic purpura) in children:

etiology, pathogenesis, classification, clinic, diagnosis, differential diagnosis, treatment,

prevention, prognosis. Hemorrhagic vasculitis: in children: etiology, pathogenesis, classification,

clinic, diagnosis, differential diagnosis, treatment, prevention, prognosis. Emergency care for

bleeding in children.

Topic 7. Leukemia in children.

Leukemias in children: etiology, pathogenesis, classification, clinic, diagnosis, differential

diagnosis, treatment, prevention, prognosis.

Topic 8. Lymphomas in children

Lymphomas in children: etiology, pathogenesis, classification, clinic, diagnosis,

differential diagnosis, treatment, prevention, prognosis.

CONTENT MODULE 3. Diseases of the endocrine system in children

Topic 9. Thyroid disease in children.

Classification of thyroid diseases in children. Etiology, pathogenesis, clinic, diagnosis,

differential diagnosis, treatment, prevention and prognosis of diffuse toxic goiter, hypothyroidism,

autoimmune thyroiditis, endemic goiter in children. Emergency care for thyrotoxic crisis in

children.

Topic 10. Diabetes mellitus in children.

Diabetes mellitus in children: definition, etiology, pathogenesis, classification, clinic,

diagnosis, differential diagnosis, treatment, prevention, prognosis. Acute and chronic

complications of diabetes in children. Hyperglycemic (ketoacidotic) and hypoglycemic coma in

children: causes, pathogenesis, clinic, diagnosis, differential diagnosis, emergency care,

prevention.

Topic 11. Diseases of the adrenal glands and adenohypophysis.

Etiology, pathogenesis, classification, clinic, diagnosis, treatment.

Topic 12. Pathologies of growth and sexual development in children.

Definition, etiology, pathogenesis, classification, clinic, diagnosis.

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The structure of the discipline

"PEDIATRICS. CHILDREN'S INFECTIOUS DISEASES »

STRUCTURE OF CREDIT CONTENT MODULE 1.

Neonatology. Diseases of the blood and endocrine system in children

Topic Lectures Practical

training

Self-

work

Content module 1. Premature babies. The main diseases of the newborn period

1. Features of adaptation of premature newborns.

Organization of care and feeding of premature babies.

0 4.6 1,5

2. Asphyxia of newborns. Cardiopulmonary

resuscitation. SDR (basics)

1 4.6 1,5

3. Hemolytic disease of newborns 1 4.6 1,5

4. Bacterial and TORCH infections in newborns

Pneumonia in newborns.

4.6 5,5

Content module 2. Diseases of the blood system in children

5. Deficiency and aplastic anemias in children 1 4.6 1,5

6. Hemorrhagic diseases in children 1 4.6 1,5

7. Leukemia in children. 0 4.6 1,5

8. Lymphomas in children 0 4.6 1,5

Content module 3. Diseases of the endocrine system in children

9. Thyroid disease in children 1 4.6 1,5

10. Diabetes mellitus in children. Diagnosis and

treatment Emergency care for insects

1 4.6 1,5

11. Diseases of the hypothalamic-pituitary system and

adrenal glands of children

4.6 1,5

12. Diseases of the gonads in children. Growth

pathology

4.6 1,5

13. Final control 4,8 5

Total hours: - 120 of them: 6 60 39

Credits ECTS – 3.5; Classroom work –63%, self-work – 37%

MODULE 1. Neonatology. Diseases of the blood and endocrine system in children

(lectures)

№ Topic Nu

mber

of

hours

1

Acute and chronic fetal hypoxia and neonatal asphyxia. Perinatal CNS injuries of

hypoxic and traumatic origin. Modern diagnostic methods. The concept of

"encephalopathy", classification.

1

2 Hemolytic disease of newborns 1

3 Anemia in children. Causes, mechanisms of development, classification, clinical

manifestations and modern methods of treatment. Prevention of anemia

1

4 Bleeding diseases: hemostasis, classification, clinic of some nosological forms.

Treatment. Hypercoagulation. (Hemorrhagic vasculitis Shenlein - Genoa)

1

5 Diabetes mellitus in children. Coma, emergency care for insects 1

6 Thyroid disease 1

Total 6

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Neonatology. Diseases of the blood and endocrine system in children

Topics of practical classes

№ Topic Numb

er of

hours

1 Features of adaptation of premature newborns. Organization of care and feeding

of premature babies.

4.6

2. Asphyxia of newborns. SDR. Cardiopulmonary resuscitation of newborns. 4.6

3 Hemolytic disease of newborns. Conjugative jaundice in newborns. Curation of

patients and writing a medical history

4.6

4 Bacterial infections and TORCH - infections in newborns. Pneumonia in

newborns

4.6

5 Deficiency and aplastic anemias in children 4.6

6 Hemorrhagic diseases in children 4.6

7 Leukemia in children. . Curation of patients and writing a medical history 4.6

8 Lymphomas in children 4.6

9 Diseases of the thyroid gland and thyroid glands 4.6

10 Diabetes mellitus in children, etiology, classification, diagnosis,

treatment.Гострі та хронічні ускладнення. Невідкладні стані.

4.6

11 Diseases of the adrenal glands in old age. Hyper- and hypocorticism. Acute

adrenal insufficiency. Congenital dysfunction of the adrenal cortex. (adreno-

genital syndrome). . Curation of patients and writing a medical history

4.6

12 Pathology of growth and sexual development in children. Diseases of the

hypothalamic-pituitary system in children.

4.6

13. Final control 4,8

Total hours 60,0

MODULE 1. Neonatology. Diseases of the blood and endocrine system in children

Independent work of students

№

Tipes of independent work Number of

hours

Types of control

1 Preparation for practical classes 19 Current control in practical

classes

2 Elaboration of topics that are not

included in the lesson plan:

5 Summarazing module control

3 Individual independent work:

curation of patients and writing a

medical history, protection of medical

history.

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Final modular control

4 Preparation for the final modular

control

5 Final modular control

Total hours 39

Individual tasks

Module 1: Neonatology, diseases of the blood and endocrine system in children

In order to deepen, generalize and consolidate the knowledge that students receive in the

learning process, as well as the application of this knowledge in practice, as a mandatory individual

task with certain assessment criteria, curation of patients considered.

1. Curation and report on the medical history of a child with a high degree of prematurity.

2. Curation and report of the history of the child with asphyxia of the newborn.

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3. Curation and report of the medical history of a child with respiratory disorders

4. Curation and report of the history of the child with hemolytic disease of newborns

5. Curation and report of a child with Blackfan-Diamond anemia.

6. Curation and report of a child with hereditary microspherocytosis.

7. Curation and report of a child with Willibrandt's disease.

8. Curation and report of a child with Glanzman's thrombocytopathy.

9. Curation and report of a child with hemophilia.

10. Curation and report of a child with acute myeloblastic leukemia.

11. Curation and report of a child with thyroid cancer.

12. Curation and report of a child with adrenogenital syndrome.

13. Curation and report of a child with premature sexual development.

14. Curation and report of a child with diabetes.

Teaching methods

When studying the discipline "Pediatrics, Pediatric Infectious Diseases" uses a variety of

teaching methods recommended for high school, namely:

- by sources of knowledge: verbal (explanation, lecture, conversation, discussion); visual

(demonstration); practical (practical work, mastering practical skills);

- by the logic of the educational process: analytical (determination of the general condition

of the patient and the main signs of the disease), synthetic (clarification of the relationship of the

main signs of diseases, determination of optimal measures for diagnosis, treatment and

prevention), their combination - analytical-synthetic, and inductive method, deductive, their

combination - translational method;

- by the level of independent mental activity: problematic, partially exploratory, research.

Combining and generalizing the above teaching methods, when studying the discipline it

is advisable to implement such methods of organizing classes as:

- method of clinical cases,

- problem-oriented method,

- method of individual educational-research and practical tasks,

- method of competitive groups,

- method of training technologies,

- method of "business game",

- method of "brainstorming",

- method of holding conferences with the use of interactive, interdisciplinary and

information and computer technologies.

Types of educational activities of the student, according to the Curriculum, are lectures,

practical classes, independent work of students.

Thematic plans of lectures, practical classes and independent work ensure the

implementation in the educational process of all topics that are part of the modules.

Lectures. Preference is given to problem-based, review and conceptual-analytical lectures.

During the lecture, students develop knowledge, provide a motivational component and a general-

oriented stage of mastering scientific knowledge. Lectures play a role in the quality management

of students' independent work.

Practical classes are held in the mode of rotation of modules of clinical disciplines.

According to the method of organization, they are clinical, aimed at controlling the assimilation

of theoretical material and the formation of practical skills, as well as the ability to analyze and

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apply the acquired knowledge to solve practical problems. They include:

- history taking;

- examination of a sick child;

- planning the examination of a sick child;

- interpretation of laboratory and instrumental research data;

- conducting differential diagnosis of the most common diseases of childhood in their

typical course;

- determination of the preliminary clinical diagnosis;

- definition of therapeutic tactics;

- appointment of medical nutrition;

- providing emergency medical care;

- solving situational problems;

- practice of practical skills on models and at the bedside of a sick child;

- keeping medical records.

The duration of one practical lesson, taking into account the standards of weekly classroom

workload and distribution of hours for the study of pediatrics and pediatric infectious diseases is

5.0 academic hours.

Independent work of the student is one of the organizational forms of study, which is

regulated by the working curriculum and is performed by the student independently outside the

classroom. Possible types of independent work of students: preparation for practical classes and

study of topics considered only in terms of independent student work, filling out a workbook on

the discipline, search and study of additional literature, creating algorithms, structural and logical

schemes, writing abstracts, annotations, reports for speeches with messages in practical classes,

duty in the clinic outside of school hours. The organization of independent work in the departments

of the pediatric hospital should be provided by teachers of the department.

Distribution of points assigned to students

When mastering each topic of the module, the current educational activity of the student is

evaluated on a multi-point scale, then the points are converted for evaluation on the traditional 4-

point scale.

Traditional assessment

Module 1

“5” 6

“4” 5

“3” 4

“2” 0-2

The list of theoretical questions for summarizing module control.

MODULE 2. Neonatology. Diseases of the blood and endocrine system in children.

1. Definition of "prematurity". Classification of premature infants according to the

indicator "body weight at birth" and the ratio of physical development and gestational age.

2. The reasons for the delay of fetal development. Features of adaptation of children with

ZVUR and principles of nursing.

3. Assessment of morphological and neuro-functional maturity of premature infants

(Ballard scale).

4. Features of thermoregulation of premature babies, methods of hypothermia prevention.

5. Prevention and treatment of hypoglycemia in premature infants.

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6. Mechanisms of development of hyperbilirubinemia of prematurity, possible

consequences. Driving tactics.

7. Emergency care for apnea in premature babies. Indications for the use of artificial lung

ventilation. Complications of long-term mechanical ventilation: bronchopulmonary dysplasia,

retinopathy of prematurity.

8. Stages of nursing premature babies. Principles of transportation. Criteria for discharge

from the hospital.

9. Peculiarities of dispensary observation of premature children in the polyclinic.

Prevention of anemia, lactase deficiency, dysbacteriosis, rickets.

10. Principles of feeding premature infants. The choice of feeding means depending on the

gestational age and condition of the child. Recommended volumes of enteral nutrition.

11. Etiological, clinical and laboratory criteria for the diagnosis of "neonatal asphyxia".

12. Modern ideas about the pathogenesis of asphyxia. Compensatory mechanisms of the

fetus in response to hypoxia.

13. Criteria for the severity of asphyxia depending on the assessment on the Apgar scale,

pH and signs of dysfunction of organs and systems.

14. Algorithm for providing emergency care to a child in a state of asphyxia at birth,

depending on the presence or absence of signs of meconium aspiration.

15. Definition of the term "birth trauma" and factors of its development.

16. Childbirth soft tissue injuries. Adiponecrosis. Damage to the sternocleidomastoid

muscle. Differential diagnosis of labor and cephalohematoma.

17. Childbirth injury of the spinal cord and humeral plexus. Paresis and paralysis of

Duchenne-Erb, Degerin-Klumpke.

18. Differential diagnosis of intracranial hemorrhage of hypoxic and traumatic origin in

newborns.

19. The concept of the surfactant system of the lungs. Factors in the development of SDR

in newborns. The mechanism of development of hyaline membranes. Methods of antenatal

prevention.

20. Estimation of the severity of respiratory failure in the syndrome of respiratory disorders

using the Silverman and Downes scale.

21. Methods of antenatal prediction and postnatal diagnosis of SDR. Radiological signs of

SDR.

22. Principles of treatment of SDR in newborns. Respiratory support. Surfactant

replacement therapy.

23. Classification of pneumonia in newborns depending on the route and duration of

infection. Etiology.

24. Risk factors for pneumonia in newborns. Pathogenesis.

25. Features of pneumonia in newborns depending on the route of infection and etiology.

26. Principles of diagnosis and treatment of pneumonia in newborns. Features of etiotropic

therapy.

27. Erythrocyte antigenic systems of human blood. Etiology, pathogenesis of GHN.

28. Classification of GHN. Clinical and laboratory criteria for anemic, icteric and

edematous forms of GHN.

29. Criteria for the severity of GHN. Stages of bilirubin encephalopathy.

30. Methods of antenatal diagnosis and prevention of hemolytic disease of the fetus.

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31. Indications for replacement blood transfusion surgery. Technique of operation and its

possible complications.

32. Methods of conservative therapy of GHN. The mechanism of action of phototherapy.

33. Features of the hemostasis system in newborns. Factors in the development of

hemorrhagic disease. Clinical features of early, classical and late forms of hemorrhagic disease.

34. Differential diagnosis of hemorrhagic disease and "swallowed blood" syndrome.

Emergency care for gastrointestinal bleeding. Treatment and prevention of hemorrhagic disease.

35. Definition of the term "TORCH infection". Risk factors for the development of VUI.

36. The nature of the lesion in VUI depending on the timing and route of infection of the

fetus.

37. Methods of early diagnosis and prevention of VUI.

38. Clinical manifestations of VUI depending on the etiology (congenital toxoplasmosis,

rubella, neonatal herpes and cytomegalovirus infection).

39. Principles of treatment of VUI. Etiotropic and immunotherapy.

40. Omphalitis. Etiology. Pathogenesis. Classification. Diagnosis. Prevention and

treatment.

41. Vesiculopustulosis, neonatal vesicles, Ritter's exfoliative dermatitis. Etiology, clinic,

treatment. Prevention.

42. Definition of the term "neonatal sepsis". Development factors.

43. Classification and etiology of neonatal sepsis.

44. Clinical and laboratory criteria for neonatal sepsis.

45. Principles of treatment and prevention of neonatal sepsis.

46. Definition of anemia. Classification of anemias in children.

47. Iron deficiency anemia in children. Causes, clinic, diagnosis, differential diagnosis.

48. Treatment and prevention of deficient anemias in children.

49. Aplastic anemia in children. Etiology, pathogenesis, diagnosis. Urgent help with

bleeding.

50. Leukemia in children. Causes. Classification of leukemias. Its connection with the

hematopoietic scheme.

51. Clinical variants of the course, diagnosis and differential diagnosis of acute

lymphoblastic leukemia in children.

52. Leukemia treatment programs in children (acute lymphoblastic leukemia, acute

myeloid leukemia, chronic myeloid leukemia). Cytostatics. Classification of drugs used as

cytostatics. Indications for their use. Complications of cytostatic therapy (immediate, delayed,

remote).

53. Classification of hemoblastosis. Lymphogranulomatosis in children. Etiology,

pathogenesis, stages of the disease (according to Ann Arbor).

54. Diagnosis, differential diagnosis of lymphogranulomatosis in children with other

lymphadenopathy, lymphadenitis; hemoblastosis.

55. Clinic, treatment, prognosis of lymphogranulomatosis in children. Emergency care for

superior vena cava compression syndrome.

56. The concept of bleeding diseases. Classification.

57. Hemophilia A and B. Etiology, pathogenesis, clinic, diagnosis. Prognosis in children.

58. Replacement therapy in the provision of emergency care to patients with hemophilia.

Antihemophilic drugs (concentrates of coagulation factors, SZP) and their use.

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59. Hemorrhagic vasculitis in children. Etiology, pathogenesis, clinical forms, diagnostics,

differential diagnosis, treatment, prognosis.

60. Thrombocytopenic purpura in children. Etiology, pathogenesis, clinic, diagnosis,

differential diagnosis, treatment, prognosis. Emergency care for bleeding.

61. Diabetes mellitus in children. Etiology, pathogenesis, clinic, diagnosis, principles of

treatment, criteria for compensation of diabetes mellitus in children.

62. Peculiarities of diabetes mellitus in early and adolescence.

63. Regime of insulin therapy of diabetes mellitus in children. Insulin preparations.

Classification

64. Peculiarities of diet in compensated and uncompensated diabetes mellitus in children.

65. Hyperglycemic ketoacidotic coma in children. Causes, clinic, diagnosis, emergency

care.

66. Hypoglycemic coma in children. Causes, clinic, diagnosis, emergency care.

67. Differential diagnosis of hyperglycemic and hypoglycemic coma in children.

68. Growth disorders in children. Pituitary dwarfism. Causes, clinic, differential diagnosis.

Treatment and prognosis. Somatogenous dwarfism.

69. Thyroiditis in children (acute, subacute and chronic) Autoimmune thyroiditis in

children. Etiology, pathogenesis, clinic, diagnosis, differential diagnosis, treatment, prognosis.

70. Diffuse toxic goiter in children. Etiology, pathogenesis, clinic, diagnosis, differential

diagnosis. Treatment. Forecast.

71. Endemic goiter in children. Causes, clinic, diagnosis, treatment, prevention.

72. Hypothyroidism in children. Etiology, pathogenesis, clinic, early diagnosis. Treatment,

prognosis.

73. Clinic and diagnosis of congenital hypothyroidism in children. Treatment. Forecast.

74. Etiology, genetic aspects, clinic and diagnosis of adreno-genital syndrome in children.

Treatment. Emergency care for the losing form of adreno-genital syndrome.

75. Disorders of sexual development in boys and girls. Etiology, pathogenesis, clinic,

diagnosis, differential diagnosis, treatment of hypogonadism and premature sexual development.

The list of practical tasks and works for summarizing module control

1. Collection of medical history and life.

2. Assessment of the general condition of the child.

3. Objective examination of a sick child.

4. Formulation of a preliminary diagnosis.

5. Appointment of additional examinations.

6. Differential diagnosis.

7. Appointment of a course of treatment.

8. Medical examination of the patient.

9. Ability to prescribe drugs used in the treatment of the pathology under study. Know the

main groups of drugs used for treatment.

10. Providing emergency care for emergencies in children that may accompany the somatic

diseases being studied.

Control methods

Methods and forms of control and evaluation of student performance in the discipline are

carried out in accordance with the requirements of the program and Instructions for evaluating

students' learning activities in the implementation of the European credit transfer system, approved

16

by the Ministry of Health of Ukraine (letter of the Ministry of Health of Ukraine № 08.01-47 /

10395 from 15.04. 2014); as well as the Regulations on the procedure for assessing students'

knowledge during the current and final control of the discipline at NMU named after OO

Bogomolets (Supplement to Order №782 of September 30, 2019).

When assessing students' knowledge, preference is given to standardized methods of

control: testing, structured written work, work with standard medical records, standardized method

of control of practical skills.

Forms of control

Current control is carried out at each practical lesson in accordance with the specific

objectives of the topic. All practical classes use objective control of theoretical training and

acquisition of practical skills (standardized by the method of execution).

The final control is carried out upon completion of the study of the block of relevant topics

in the last lesson of the module (final control).

The control of the performance of independent work, which is provided in the topic along

with the classroom work, is carried out during the current control of the topic in the relevant

classroom. Control of the acquisition of practical skills on the relevant topic of the lesson is carried

out both during the current control and during the final control.

Control methods

Theoretical knowledge:

- written and computer testing,

- individual survey, interview,

- structured in content written works.

Practical skills and abilities:

- control over the implementation of standardized methods of practical skills provided for

in the plan of practical training of students in the discipline:

- analysis of laboratory and instrumental research;

- performing medical manipulations in pediatrics;

- providing assistance in emergencies in children.

Distribution of points received by students

The current assessment of students on relevant topics is carried out at each practical lesson

in accordance with the specific objectives of each topic on the traditional 4-point system (excellent,

good, satisfactory, unsatisfactory) with subsequent conversion into a multi-point scale. The weight

of each topic in points within one module is the same and is determined by the number of topics

in the module.

REGULATIONS FOR EVALUATION OF CURRENT STUDENT RESULTS

Module 1 "Neonatology, diseases of the blood and endocrine system in children"

Current control is carried out at each practical lesson in accordance with the specific

objectives of each topic.

The student's readiness for the lesson (initial stage) is checked on the basis of the answer

to 10 test tasks. In the first practical lesson, these questions are included in the final control. For

the correct answer to 9-10 tests the student receives 1 point; for 7-8 tests - 0.5 points; on 0-6 tests

0 points. The main stage of practical training involves work in the clinic, supervision of patients.

The control of the main stage of the lesson is carried out by assessing the student's performance of

practical skills, analysis of his participation in the activities of the clinical department, the ability

to solve typical situational problems. The survey is rated 3, 2, 1, 0 points. At the final stage of the

17

lesson the result of the student's practical activity is made, the task is given for the time of the

student's independent work after the end of the classroom part of the lesson. To assess the student's

mastery of the topic, he is asked to answer a situational problem. If the problem is solved correctly

- the student receives 2 points, if with 1-2 minor errors - 1 point. The scores obtained during the

lesson are added (scores obtained for tests + scores obtained for the survey + scores obtained for

the tasks). Recalculation of scores on a multi-point scale is as follows: Score "excellent" - 6 points,

"good" - 5 points, "satisfactory" - 4 points, "unsatisfactory" - 0-3 points.

In topics 3, 7 and 11, assessment is conducted separately for the topic of the lesson and

separately for writing a medical history, which is assessed with 8, 6, 4 points.

Assessment of independent work of students in preparation for classroom practical classes

is carried out during the current control of the topic in the relevant classroom.

Assessment of mastering the topics that are submitted only for independent work and are

not included in the topics of classroom training, is carried out during the final control.

The maximum number of points that a student can score for the current academic activity

is 80 points. It is calculated by adding the number of points that correspond to the grade "excellent"

in each practical lesson (6 points for topics №1-12) with the addition of the maximum score for

the case history (8 points).

The minimum number of points is not determined.

The final control is carried out upon completion of the study of all topics of the module at

the last control session of the module.

Students are admitted to the final control provided that they attend at least 75% of the

classroom classes with the entire accumulated amount of points during the study of the discipline.

If a student has attended less than 75%, he/she is considered to have failed the curriculum and

syllabus in the discipline, and therefore has to re-study the discipline.

The form of summarizing module control is standardized and includes control of theoretical

and practical training. Distribution of points - for the theoretical part - 60 points (test tasks in the

amount of 30), for the practical part of 60 points (solving 3 typical problems of 20, 16, 13 points,

respectively, for the correct, with a small error and two minor errors in each task).

The maximum number of points of the final modular control is 120.

The final control is considered credited if the student has scored at least 111 points (E),

which consists of the sum of points for the current study and the result of the practical classes.

Encouraging points may be added to the number of points in the discipline by students who

have scientific publications or won prizes in international and national competitions in related

disciplines, but the total number of points for the discipline may not exceed 200 points.

The objectivity of the assessment of students' learning activities should be checked by

statistical methods (correlation coefficient between current performance and the results of the final

module control).

Converting the number of points out the the discipline into ECTS scale and

traditional marks

Points from the discipline are independently converted into both the ECTS scale and the

four-point scale at the department.

Ranking on the ECTS scale with the assignment of grades "A", "B", "C", "D", "E" is as

follows:

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Rating ЕСТS Points

А 170-200

В 155-169

С 140-154

D 125-139

E 111-124

FX 60-110

F 1-59

Upon receipt of the FX grade, the student is entitled to 2 re-grades until the next academic

year according to the approved schedule. The first reshuffle - the cathedral commission, the second

time - the commission with the participation of the dean. In the assessment of F - re-study of the

discipline before the new school year in the group for a fee for extracurricular activities.

Also, points from the discipline are converted at the department into a traditional four-point

scale according to absolute criteria as follows:

Points on discipline Traditional marks

170-200 points 5

140-169 points 4

139-111 points 3

Less than 100 points 2

Methodical support

All types of educational activities have methodological support: lectures, practical classes,

independent work of students.

Methodical support of the lecture course:

1. Abstracts of lectures.

2. Methodical development of lectures.

3. Lecture presentations.

4. Videos and educational films on the topics of lectures.

Methodical support of practical classes:

1. Methodical development of practical classes for teachers.

2. Methodical instructions for practical classes for students.

3. Variants of test questions and tasks to check the initial level of knowledge on each topic.

4. Variants of situational tasks to check the mastery of topics.

5. Variants of tasks (theoretical and practical) for the final modular control.

6. Instructions for working with phantoms and dummies to practice practical skills.

Methodical support of independent work of students:

1. Methodical instructions for pre-classroom preparation for practical classes.

2. Methodical instructions for practical skills.

3. Task options for independent work of students.

Tools for diagnosing learning success

The following tools are used to diagnose learning success:

1. Test tasks of format A

2. Practical tasks to test the mastery of practical skills

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3. Situational tasks.

The development of test-control questions, structured situational tasks and practical tasks

used to diagnose learning success should be based on a list of questions and practical skills that a

student must learn when studying modules № 1 and 2 of the discipline "Pediatrics, Pediatric

Infectious Diseases". Sets of practical tasks are formed from the list of practical skills that the

student must master while studying the discipline, which are standardized by the method of

practical work.

LIST OF QUESTIONS FOR SUMMARAZING MODULE CONTROL

1. Organization of neonatal care in Ukraine.

2. Medical care for a healthy newborn child.

3. Medical care for a newborn baby with low birth weight.

4. Definition of "prematurity". Classification of premature infants according to the

indicator "body weight at birth" and the ratio of physical development and gestational age.

5. Causes of fetal growth retardation. Features of adaptation of children with ZVUR and

principles of nursing.

6. Assessment of morphological and neuro-functional maturity of premature infants (on the

Ballard scale).

7. Features of thermoregulation of premature babies, methods of hypothermia prevention.

8. Prevention and treatment of hypoglycemia in premature infants.

9. Mechanisms of development of hyperbilirubinemia of premature infants, possible

consequences. Driving tactics.

10. Emergency care for apnea in premature babies. Indications for the use of artificial lung

ventilation. Complications of long-term mechanical ventilation: bronchopulmonary dysplasia,

retinopathy of prematurity.

11. Stages of nursing premature babies. Principles of transportation. Criteria for discharge

from the hospital. Peculiarities of dispensary observation of premature children in the polyclinic.

Prevention of anemia, lactase deficiency, dysbacteriosis, rickets.

12. Principles of breastfeeding premature infants. The choice of feeding method depending

on the gestational age and condition of the child.

13. Etiological, clinical and laboratory criteria for the diagnosis of "neonatal asphyxia", the

pathogenesis of asphyxia. Criteria for the severity of asphyxia.

14. Primary resuscitation of newborns and post-resuscitation care for newborns.

15. Definition of the term "birth trauma" and factors of its development.

16. Childbirth soft tissue injuries. Adiponecrosis. Damage to the sternocleidomastoid

muscle. Differential diagnosis of labor and cephalohematoma.

17. Childbirth injury of the spinal cord and humeral plexus. Paresis and paralysis of

Duchenne-Erb, Degerin-Klumpke.

18. Differential diagnosis of intracranial hemorrhage of hypoxic and traumatic origin in

newborns.

19. The concept of the surfactant system of the lungs. Factors of RDS development in

newborns. Methods of antenatal prevention.

20. Assessment of the severity of respiratory failure in RDS. Diagnosis of RDS.

21. Principles of treatment of RDS in newborns.

22. Classification of pneumonia in newborns depending on the route and duration of

20

infection. Etiology.

23. Risk factors for pneumonia in newborns. Pathogenesis. Features of pneumonia in

newborns depending on the route of infection and etiology.

24. Principles of diagnosis and treatment of pneumonia in newborns. Features of etiotropic

therapy.

25. Erythrocyte antigenic systems of human blood. Etiology, pathogenesis of GHN.

Classification. Clinical and laboratory criteria for anemic, jaundiced and edematous forms of

GHN. Stages of bilirubin encephalopathy.

26. Methods of antenatal diagnosis and prevention of hemolytic disease of the fetus.

Treatment of hemolytic disease of newborns. Indications for replacement blood transfusion

surgery. Technique of operation and its possible complications.

27. Features of the hemostasis system in newborns. Factors in the development of

hemorrhagic disease. Clinical features of early, classical and late forms of hemorrhagic disease.

28. Differential diagnosis of hemorrhagic disease and "swallowed blood" syndrome.

Emergency care for gastrointestinal bleeding. Treatment and prevention of hemorrhagic disease.

29. Definition of the term "TORCH infection". Risk factors for the development of VUI.

The nature of the lesion in VUI depending on the timing and route of infection of the fetus.

Methods of early diagnosis and prevention of VUI.

30. Clinical manifestations of VUI depending on the etiology (congenital toxoplasmosis,

rubella, neonatal herpes and cytomegalovirus infection). Principles of VUI treatment. Etiotropic

and immunotherapy.

31. Omphalitis. Etiology. Pathogenesis. Classification. Diagnosis. Prevention and

treatment.

32. Vesiculopustulosis, neonatal vesicles, exfoliative Ritter's dermatitis. Etiology, clinic,

treatment. Prevention.

33. Definition of the term "neonatal sepsis". Development factors. Classification, etiology,

clinical and laboratory diagnostic criteria. Principles of treatment and prevention of neonatal

sepsis.

34. Issues of bioethics in modern perinatology and neonatology.

35. Definition of anemia. Classification of anemias in children.

36. Iron deficiency anemia in children. Causes, clinic, diagnosis, differential diagnosis.

Treatment and prevention of iron deficiency anemia in children.

37. Posthemorrhagic anemia in children. Etiology, pathogenesis, diagnosis. Emergency

care for bleeding.

38. Leukemia in children. Causes. Classification of leukemias. Its connection with the

hematopoietic scheme. Clinical variants, diagnosis and differential diagnosis of acute

lymphoblastic leukemia in children.

39. Principles of treatment of leukemias in children (acute lymphoblastic leukemia, acute

myeloid leukemia, chronic myeloid leukemia). Cytostatics. Classification of drugs used as

cytostatics. Indications for their use. Complications of cytostatic therapy (immediate, delayed,

remote).

40. Classification of hemoblastosis. Lymphogranulomatosis in children. Etiology,

pathogenesis, stages of the disease.

41. Diagnosis, differential diagnosis of lymphogranulomatosis in children with other

lymphadenopathy, lymphadenitis, hemoblastosis. Clinic, treatment, prognosis of

21

lymphogranulomatosis in children. Emergency care for superior vena cava compression syndrome.

42. Classification of hemorrhagic diseases in children.

43. Hemophilia A and B. Etiology, pathogenesis, clinic, diagnosis. Prognosis in children.

Replacement therapy in the provision of emergency care to patients with hemophilia.

Antihemophilic drugs (concentrates of coagulation factors, SZP) and their use.

44. Hemorrhagic vasculitis in children. Etiology, pathogenesis, clinical forms, diagnostics,

differential diagnosis, treatment, prognosis.

45. Thrombocytopenic purpura in children. Etiology, pathogenesis, clinic, diagnosis,

differential diagnosis, treatment, prognosis. Emergency care for bleeding.

46. Diabetes mellitus in children. Etiology, pathogenesis, clinic, diagnosis. Peculiarities of

diabetes mellitus in early and adolescence. Criteria for compensation of diabetes mellitus in

children.

47. Regime of insulin therapy of diabetes mellitus in children. Insulin preparations.

48. Peculiarities of diet in compensated and uncompensated diabetes mellitus in children.

49. Hyperglycemic ketoacidotic coma in children. Causes, clinic, diagnosis, emergency

care.

50. Hypoglycemic coma in children. Causes, clinic, diagnosis, emergency care.

51. Differential diagnosis of hyperglycemic and hypoglycemic coma in children.

52. Growth disorders in children. Pituitary dwarfism. Causes, clinic, differential diagnosis.

Treatment and prognosis.

53. Obesity in children. Causes, clinical forms. Principles of complex treatment of various

clinical forms of obesity in children. Prevention.

54. Autoimmune thyroiditis in children. Etiology, pathogenesis, clinic, diagnosis,

differential diagnosis, treatment, prognosis.

55. Diffuse toxic goiter in children. Etiology, pathogenesis, clinic, diagnosis, differential

diagnosis. Treatment. Forecast.

56. Endemic goiter in children. Causes, clinic, diagnosis, treatment, prevention.

57. Hypothyroidism in children. Etiology, pathogenesis, clinic, early diagnosis. Treatment,

prognosis.

58. Clinic and diagnosis of congenital hypothyroidism in children. Treatment. Forecast.

59. Clinic and diagnosis of adreno-genital syndrome in children. Treatment. Emergency

care for the loss-making form of adreno-genital syndrome.

60. Disorders of sexual development in boys and girls. Etiology, pathogenesis, clinic,

diagnosis, differential diagnosis, treatment.

61. Differential diagnosis of variants of intersexualism. Research methods. Principles of

treatment.

62. Anemia, which is associated with impaired hematopoiesis.

LIST OF PRACTICAL SKILLS FOR SUMMARAZING MODULE CONTROL

I. Analysis of laboratory and instrumental studies in children

1. General clinical blood test

2. General clinical analysis of urine

3. General analysis of feces

4. Blood protein and its fractions, acute phase parameters

5. Blood glucose

22

6. Lipid profile of blood

7. Blood electrolytes

8. Blood transaminases

9. Creatinine, blood urea

10. Total blood bilirubin and its fractions, analyze the Polachek curve

11. Coagulogram

12. ECG

11. Radiation examination of the CNS, thoracic and abdominal organs, urinary system,

thyroid gland, skull, bones, joints.

12. Microbiological study of biological fluids and secretions 13. Polymerase chain

reaction, enzyme-linked immunosorbent assay

14. General analysis of sternal punctate

15. General analysis of cerebrospinal fluid

ІІ. Medical manipulations in pediatrics

1. To determine blood groups, rhesus affiliation in children

2. Perform artificial respiration, indirect heart massage in children

3. Measure blood pressure in children

4. Conduct the primary toilet of the newborn

5. Carry out ECG recording in children

6. Inject drugs into children

III. Providing emergency care for children

1. Asphyxia of newborns

2. Acute respiratory failure in newborns

3. Convulsive syndrome in children

4. Bleeding in children

5. Hemorrhagic shock in children

6. Hyperglycemic ketoacidotic and hypoglycemic coma in children

7. Thyrotoxic crisis in children

References

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2. Nelson Texbook of Pediatrics. 20th edition. – V(1,2). – 2016. – P.5315.

3. Klingensmith GJ (Ed.): Intensive Diabetes Management. 3rd ed. Alexandria, VA,

American Diabetes Association, 2003.

4. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Follow-

up report on the diagnosis of diabetes mellitus. Diabetes Care 26:3160–3167, 2003.

5. https://www.guidelines.co.uk/diabetes/nice-type-1-diabetes-in-children-

guideline/252660.article.

6. Sharma ST, Nieman LK, Feelders RA. Cushing’s syndrome: epidemiology and

developments in disease management. Clin Epidemiol. 2015. - 7:281–293.

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