Miki Lee / OEB 192 – 08.11.12 Mobile genetic elements and adaptive mutation.
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Miki Lee / OEB 192 – 08.11. Mobile genetic elements and adaptive mutation
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Transcript of Miki Lee / OEB 192 – 08.11.12 Mobile genetic elements and adaptive mutation.
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Miki Lee / OEB 192 – 08.11.12
Mobile genetic elements and adaptive mutation
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IS familyhttp://www-is.biotoul.fr/
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Effects on bacterial evolution
• An important source of genetic variation– Insertion
– Homologous recombination
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Effects on bacterial evolution
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— M-evolved— S-evolved— M+S-evolved— M/S-evolved
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MutationLuria–Delbrück experiment Cairns–Foster system
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Modified Cairns–Foster system
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Kugelberg E. et.al. PNAS 2006;103:17319-17324
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Monday (11/17): Physiological basis of fitness
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