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    Benchmarking Performanceof Mexican States Using

    Effective Coverage

    Rafael Lozano, Patricia Soliz, Emmanuela Gakidou, JesseAbbott-Klafter, Dennis M Feehan, Cecilia Vidal, Juan

    Pablo Ortiz, Christopher JL Murray

    Health System Metrics

    Glion, SwitzerlandSeptember 28-29 2006

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    Outline

    Background

    Effective coverage at sub-nationallevel Selecting interventions

    Measurement strategies

    Results

    Selected interventions Health system effective coverage

    Lessons learned

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    Background

    National Health Program 2001-2006

    Goals, Strategies and Activities

    Health Reform in Mexico 2004-2010 Formula for resource allocation

    WHO HSPA framework 2000 and newversions

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    Information and Local Capacity

    National Health surveys

    World Health Survey

    National survey of health system performance(2002)

    Administrative records

    Links from the MOH with HIGH and N

    IPH

    Publications, workshops

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    States 32

    Counties2.4 thousandsLocalities199 thousands

    Mexico 2005

    7.0 6.0 5.0 4.0 3.0 2.0 1.0 0.0 1.0 2.0 3.0 4.0 5.0 6.0 7.0

    0-4

    5 a 9

    10 a 14

    15 a 19

    20 a 24

    25 a 29

    30 a 34

    35 a 39

    40 a 44

    45 a 49

    50 a 54

    55 a 59

    60 a 64

    65 a 69

    70 a 74

    75 a 79

    80 a 84

    85 +

    Males Females

    Population Million 106.5

    Males 51.8

    Females 52.4

    % with health insurance 56.2

    % without health insurance 43.8

    % Urban Areas 74.7% Rural Areas 25.3

    Mexico 2005

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    Health Change in Mexico

    0%

    20%

    40%

    60%

    80%

    100%

    1950 1960 1970 1980 1990 2000 2010 2025

    Communicable Non Communicable Injuries

    Causes of death transition

    0%

    20%

    40%

    60%

    80%

    100%

    1950 1960 1970 1980 1990 2000 2010 2025

    0-14 15-65 65+

    Age pattern

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    Mexico Health System (2005)

    Fragmented Insured Inst, Non Insured Inst, Private

    Decentralized

    Since 80s

    Financial Unbalances

    534.2218**109**1,511106*Total (absolute)

    1,000.029.830.426.52.8Private

    216.88.5Popular Insurance

    910.03.65.27.91.5Others

    231.97.06.27.07.5ISSSTE

    324.829.926.823.135.8IMSS

    325.630.538.338.056.2With medical Insurance

    87.929.731.435.543.8No medical insurance

    Expenditure

    per

    PercapitaUSDPhysicians%Beds%Hospitals%

    Popu-

    Lation%

    * millions, ** thousands

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    Outline

    Background

    Effective coverage at sub-national level

    Selecting interventions Measurement strategies

    Results

    Selected interventions Health system effective coverage

    Lessons learned

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    Effective coverage is the synthesis of threeanalytical approaches in the study of coverage

    of health services

    Sociological

    Studies about access to

    health services,utilization, identification of

    barriers

    Economics

    Studies about health caredemand concerning prices,

    quality, distance, etc.

    Public health

    Studies of the proportion

    of the population that

    receives an intervention

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    Effective Coverage the fraction of potential health gain that

    can be delivered through an interventionby the health system that is actuallydelivered

    Steps for EC Measurement

    1. How do we identify the groupwho needs an intervention?

    2. How do we identify those who

    need an intervention thatreceived one?

    3. How do we measure quality ofthe intervention delivered?

    Defining the set of interventions

    affordability,

    total population health gain

    impact on health inequalities.

    whether a measurementstrategy for the intervention

    can be developed

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    Table 1: Selected interventions for the measurement of EC in Mexico

    Intervention Definition

    Effective coverage of measles* % of children 1-4 that have been vaccinated against measles

    Coverage of DPT3* % of children 1-4 that have been vaccinated with DPT3

    Coverage of BCG* % of children 1-4 that have been vaccinated against BCG

    Coverage of breast cancer screening % of women 40-69 that had a mammography in the last year

    Coverage of cervical cancer screening % of women 25-69 who had a pelvic exam in the last year

    Coverage of antenatal care

    % of women that had 4 or more checks and blood, urine, pressure

    tests during last pregnancy

    Coverage of skilled birth attendance % of women that had their last birth attended in hospital

    Coverage of treatment of premature

    newborns death rate among newborns 30-34 weeks of gestational age

    Flu vaccine Adults over the age of 60 have been vaccinated in the lasy year

    Coverage of treatment of diarrhea % of children under five that received ORS or more liquids during

    last episode of diarrhea in the last month

    Coverage of treatment of ARI

    % of children under five for which advice was sought from a health

    personnel in the last episode of fever/cough/pneumonia in the

    last month

    Effective coverage of treatment of vision

    disorders

    % of people who need glasses that have glasses that solve their

    vision problems

    Coverage of treatment of High Cholesterol

    Adults >20 years with total cholesterol equal to or greater than

    200mg/dl

    Effective coverage of treatment of

    hypertension

    % of people with high blood pressure that received appropriate

    treatment

    Normative

    Biological

    m

    arkers

    Oneors

    everal

    sympt

    oms

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    Measuring effective coverage in Mexico

    This exercise was carried out by the Ministry of

    Health (General Direction of Health Information), theNational Institute of Public Health and HarvardUniversity (HIGH)

    The information sources basically come from theENSA 2000, ENED 2002, ENSANUT 2005-06,

    administrative registries and vital statistics Effective coverage has been measured for 8

    interventions and coverage for 18 interventions

    Effective coverage has been estimated by state but not by health care provider

    A composite measure of effective coverage wasestimated

    The precision on each of the indicators vary accordingto the quality of the data source

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    Outline

    Background

    Effective coverage at sub-national level

    Selecting interventions Measurement strategies

    Results

    Selected interventions Health system effective coverage

    Lessons learned

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    Visual Impairment correction

    Definition

    Effective coverage for visual impairment is defined as the proportion of adultsover the age of 20 with visual impairments that have glasses or contacts thatsolve their vision problems.

    How was need estimated? Need for correction of visual impairments is measured in the ENSANut 2005-06

    by self-reports of difficulties on two items in the survey. This module of thesurvey was only applied to respondents over the age of 20 and included twoquestions on difficulties with vision. All individuals responding that they had any

    visual difficulties were included as needing correction. How was utilization estimated?

    Utilization is calculated using self-reported use of glasses or contacts.

    How was quality estimated? Quality has been estimated using the items in ENSANut 2005-06 on difficulties

    with near and far-vision using glasses or contacts. Any individual who reportsno problems on both questions in the survey is counted as having effective

    coverage. We have not weighted the measure by the magnitude of problemsreported so this is not a direct measure of the fraction of health gain deliveredby the intervention. This measure also suffers from all the comparabilityproblems that plague any measure of self-reported functional health.

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    Crude and effective coverage* of visual impairment correction for

    Mexican states and Distrito Federal, 2005-2006.

    0%

    20%

    40%

    60%

    80%

    100%

    Oax

    Chis

    Tlax

    Mich

    Tab

    Gro

    Gto

    Hgo

    Pue

    Ver

    Slp

    Mor

    Nay

    Camp

    Dgo

    Sin

    Jal

    Qroo

    Zac

    Ags

    Col

    EUM

    Yuc

    Qro

    Bcs

    Son

    Chih

    Mex

    BC

    Coah

    Tamp

    NL

    DF

    Crude Coverage

    Effective Coverage

    *95% confidence intervals

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    Services delivered to premature newborns

    Definition The fraction of the maximum possible health gain that can be delivered to

    moderately premature newborns that is actually delivered. The maximum health gainwas constructed as the difference between the expected upper and lower bound fordeath rates conditional on gestational age and birth weight.

    How was need estimated? All moderately premature newborns in Mexico; moderately premature has been

    defined as gestational age between 28 and 36 weeks and birth weight less than3500g.

    How was utilization estimated?

    We have used the same dataset to define utilization of hospital services forpremature newborns as we have used for need.

    How was quality estimated? The difference in the observed mortality rate among premature newborns compared

    to the maximum and minimum mortality rates conditional on gestational age andbirth weight that could be observed. Maximum mortality rates has been constructed from the neonatal mortality rates,

    conditional on birth weight and gestational age, recorded in the US in 1950 (2): in 1950,

    effective interventions for premature newborns were not yet available at that time so thisrepresents a reasonable approximation of no care.

    The lower bound for death rates was estimated based on a regression analysis of thestandard of care for premature newborns conditional on gestational age and birth weight inthe states of Massachusetts, New York, and New Jersey in 2000-2002, which have thelowest conditional mortality rates in the US.

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    Effective coverage of services delivered to premature newborns in Ministry ofHealth hospitals and 95% confidence intervals, 2004-2005 by Mexican state.

    0%

    20%

    40%

    60%

    80%

    100%

    Gro

    Oax

    Pue

    Bcs

    Chis

    Mor

    Coah

    Ver

    Mex

    Col

    EUM

    Gto

    Zac

    Camp

    Tlax

    Hgo

    Jal

    Mich

    DF

    Tab

    Son

    NL

    Qroo

    Chih

    Slp

    Sin

    Nay

    Dgo

    Tamp

    BC

    Qro

    Yuc

    Ags

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    Treatment of Hypertension Definition

    The ratio of actual systolic blood pressure reduction from treatment ofhypertension to potential blood pressure reduction.

    How was need estimated? In the estimation of effective coverage, need of treatment is defined as a level of

    blood pressure equal or above a threshold of 140 mmHg. The information onlevels of blood pressure is taken from the ENSANut 2005-06 survey, whichrecords for each individual aged 20 and above two measurements of systolicblood pressure (SBP), taken five minutes apart. The prevalence of the conditionis estimated using an average of the two measurements.

    How was utilization estimated? The ENSANut 2005-06 provides state representative data for the analysis ofblood pressure including self-reported information on treatment with medication.An individual is considered to be on treatment for hypertension if he or shereports currently taking medication to control his or her level of blood pressure.

    How was quality estimated? In the first stage of the analysis, we use logistic regression to model the

    probability of a respondent reporting being on anti-hypertensives as a function of

    age, sex, bmi, speaking an indigenous language, household wealth, and level ofeducation, in addition to our two instruments: insurance status and the crudecoverage of hypertension in the respondents community. Results of the first-stage IV analysis show that both instruments are highly predictive of theprobability of treatment: the area under the models ROC curve is 0.84.

    In the second stage analysis we use linear-normal regression to model bloodpressure as a function of the predicted probability of being on antihypertensives,as well as the set of non-instrumental covariates used in the first stage. The

    second stage results suggest a treatment effect of 11mmHg.

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    Crude and effective coverage and 95% confidence intervals of treatment

    for hypertension in Mexican states and Distrito Federal, 2005-2006.

    0%

    20%

    40%

    60%

    80%

    100%

    Qr

    o

    Yu

    c

    Ve

    r

    Gr

    o

    Cam

    p

    So

    n

    Hg

    o

    Qro

    o

    Si

    n

    Pu

    e

    Za

    c

    Mic

    h

    Ta

    b

    Bc

    s

    Tla

    x

    Na

    y

    Chi

    s

    Dg

    o

    EUM

    Chi

    h

    Coa

    h

    Sl

    p

    Oa

    x

    Mex

    Col

    N

    L

    Ag

    s

    Gto

    BC

    Tam

    p

    D

    F

    Mor

    Jal

    Crude Coverage

    Effective Coverage

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    CervicalCance

    rScreening,

    M

    xico2000-200

    5

    Que

    Mo r

    N L

    S lp

    Me x

    Gro

    Yu c

    BC

    EUM

    DF

    Bcs

    Ja l

    Gto

    D go

    Pue

    C amp

    T lax

    Ags

    S in

    Zac

    Oa x

    Ve r

    H g o

    C o l

    N a y

    Qroo

    Tab

    Ch i s

    ENSA2

    000

    ENSANut2005

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    Coverage of Cervical Cancer Screening, Mxico 2000 -2005

    Insurance Income Quintile

    0%

    10%

    20%

    30%

    40%

    50%

    60%

    Uninsurance Seg Popular Private Soc Insurance

    ENSA 2000 ENSANut 2005

    0%

    10%

    20%

    30%

    40%

    50%

    60%

    1 2 3 4 5

    ENSA 2000 ENSANut 2005

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    Constructing Effective

    Coverage Composites following the formal definition of effective coverage,

    each intervention could be combined in proportion to theaverage health gain it delivers to the population;

    preference weights can be derived from revealed choicesin the marketplace or from survey responses; arbitrary weights such as simple averages or other

    weights can be used; one can assume that each indicator is an imperfect

    measure of an underlying unobserved construct, healthsystem effective coverage, and use latent variabletechniques such as factor analysis or variants of probitsand logits.

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    0%

    10%

    20%

    30%

    40%

    50%

    60%

    Gro

    Oax

    Chis

    Pue

    Mich

    Ver

    Bcs

    Mor

    Sin

    Tamp

    Slp

    Chih

    EUM

    Qro

    BC

    Son

    Tlax

    NL

    Col

    Zac

    Mex

    Jal

    Coah

    Hgo

    Comp

    Inde

    EffeCove

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    0%

    20%

    40%

    60%

    80%

    100%

    1 2 3 4 5

    Quintile of Wealth

    CompositeEffectiv

    eCoverag

    Maternal andChild Health

    Other

    Interventions

    All Interventions

    Composite effective coverage (14 interventions), maternal and childhealth intervention coverage (8 interventions) and other adult

    interventions coverage (6 interventions) by household wealth quintile,Mexico 2005

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    Composite effective coverage (14 interventions) for 2005by

    state, versus the log of public health expenditure per capita.

    40%

    45%

    50%

    55%

    60%

    65%

    70%

    6.0 6.5 7.0 7.5 8.0 8.5 9.0

    Ln expenditure 2005

    EC

    2005

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    Change in effective coverage for 8 interventions measured in 2000 that are strictlycomparable to 8 interventions measured in 2005, by state, compared to the percentincrease in public spending per capita over the same time period. respiratory infection,diarrhea, cervical and breast cancer screening, skilled birth attendance, hypertension, services

    delivered to premature newborns, and antenatal care.

    -5%

    0%

    5%

    10%

    15%

    20%

    25%

    30%

    0% 10% 20% 30% 40% 50% 60% 70% 80%

    % change in expenditure, '00 to '05

    %

    changeincomparable

    EC,

    '00-'05

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    Outline

    Background

    Effective coverage at sub-national level

    Selecting interventions Measurement strategies

    Results

    Selected interventions Health system effective coverage

    Lessons learned

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    Lessons for Mexico

    Mexico is the first country to fully implement therecommendation to measuring EC at subnationallevel

    The relation between public health spendingpercapita and EC highlights the importance ofraising levels of spending per capita in thedisadvantaged states

    EC allows us to say than Mexico has two health

    systems, one for MIC and other for NonCommunicable diseases and injuries

    Improve HIS and build local capacity(investment)

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    Implications for the Mexican HealthInformation System

    More attention in future to measuring quality of interventiondelivery.

    Examination surveys produce hard endpoints in which toanchor the analysis.

    Careful attention in developing better measures of effective

    coverage, for example Diabetes. Further work is needed to characterize the biases inadministrative data for measuring effective coverage of someinterventions.

    A comprehensive information's system needs to harmonizedata collection for certain interventions across all institutions

    of public sector and even private. Because of the potential of pharmacological strategies for

    hypertension, cholesterol and possibly blood sugar (diabetes),prospective registries of treatment impact should bedeveloped.

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    Global Lessons

    Updating the philosophy of HS How much health gains is delivering the HS?

    Another way to measure access to health facilities

    EC shifts the focus to achievements

    Strengthening the economic analysis of HS resources

    Affects the four HS functions

    To revise the scope of the agenda: MDG+ framework(focusing in monitoring EC of interventions for non

    communicable and injuries)

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