Measuring the Vocal Tract Using MRI and Acoustic ...
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Undergraduate Research
Symposium
Madison, Wisconsin
13 April 2018
http://waisman.wisc.edu/vocal/
Measuring the Vocal Tract Using MRI and Acoustic Pharyngometry: A Comparison
Abigail Lamers, Ying Ji Chuang, Katelyn Tillman, Julie Eichhorn and Houri K. Vorperian
Vocal Tract Development Lab, Waisman Center, University of Wisconsin - Madison
REFERENCES:
(1) Corey, J. P., Gungor, A., Nelson, R., Fredberg, J., & Lai, V. (1997). A comparison of the nasal cross-sectional
areas and volumes obtained with acoustic rhinometry and magnetic resonance imaging. Otolaryngology - Head
and Neck Surgery, 117(4), 349-354.
(2) Corey, J. P., Nalbone, V. P., & Ng, B. A. (1999). Anatomic correlates of acoustic rhinometry as measured by rigid
nasal endoscopy. [Research Support, U.S. Gov't, P.H.S.]. Otolaryngology - Head and Neck Surgery, 121(5), 572-
576.
(3) D'Urzo, A.D. , Lawson, V.G. , Vassal, K.P. , Rebuck, A.S. , Slutsky, A.S. , & Hoffstein, V. (1987). Airway Area by
Acoustic Response Measurements and Computerized Tomography. American Review of Respiratory Disease,
135(2), 392-395.
(4) D'Urzo, A. D. , Rubinstein, I. , Lawson, V. G. , Vassal, K. P. , Rebuck, A. S. , Slutsky, A. S. , & Hoffstein, V. (1988).
Comparison of Glottic Areas Measured by Acoustic Reflections vs. Computerized Tomography. Journal of Applied
Physiology, 64(1), 367-370.
(5) Eccovision Acoustic Phayngometry [Operators Manual]. (2009). North Miami Beach, FL: Sleep Group Solutions.
(6) Fredberg, J. J., Wohl, M. E., Glass, G. M., & Dorkin, H. L. (1980). Airway area by acoustic reflections measured at
the mouth. [Research Support, U.S. Gov't, P.H.S.]. Journal of Applied Physiology, 48(5), 749-758.
(7) Min, Y. G., & Jang, Y. J. (1995). Measurements of cross-sectional area of the nasal cavity by acoustic rhinometry
and CT scanning. [Comparative Study]. Laryngoscope, 105(7 Pt 1), 757-759.
ACKNOWLEDGEMENTS:
This work was supported by NIH research grant R01 DC006282 from the National Institute on Deafness
and other Communication Disorders (NIDCD), and core grants P30 HD03352 and U54 HD090256 from the
National Institute of Child Health and Human Development (NICHD).
Extracting Quantitative Measurements:
• The VT-APh path was then used to execute a script that travels through the path
and finds the orthogonal planes between each landmark and its subsequent
increment. Intersection between the orthogonal plane and the 3D pharynx model
was extracted as boundary vertices and edges used to obtain CSAs and volumes
throughout the VT.
• The CSAs produced were then plotted as a function of distance from the lingual
aspect of the incisors/front teeth to the glottis, where the distance between the two
points represents the APh VTL.
• The resulting CSA plot was then superimposed on the acoustic pharyngogram by
having both overlap at the level of the glottis. This approach was used to infer the
anatomic equivalent location for the OPJ on the midsagittal plane of the imaging
study, and selected to divide the overall OPV into OCV and PCV.
• In addition, the cavity length measurements are obtained from the VTL:
• 1) PCL: the curvilinear distance from the OPJ, as referenced by the data from
APh study, to the level of the glottis.
• 2) OCL: the curvilinear distance from the alveolar incisor along the palate to
the OPJ.
IV. RESULTS:
Figure 3: Bar graphs comparing APh (blue) and MRI (orange) measurements for oral-cavity length (OCL),
pharyngeal cavity length (PCL) and overall vocal tract length (VTL); also, oral-cavity volume (OCV),
pharyngeal cavity volume (PCV) and vocal tract volume (VTV). Absolute differences in measurements,
plotted in gray, reveal that APh yields volumes for PCV and subsequently VTV that are somewhat inflated.
V. CONCLUSION:
• APh is a non-invasive clinical tool that is being increasingly used as a research tool to
gather VT measurement from typically and atypically developing individuals (who may
not be imaged or cannot be imaged due to medical concerns).
• Present findings confirm that APh may be used as a research tool and can be a useful
approach to study the development of the upper airway in typically and atypically
developing individuals (provided the participant is able to follow APh instructions, and
the pediatric APh mouthpiece fits).
• APh is a technique that may be used to gain information about the developmental
changes in the oral and pharyngeal cavities. Such information may be used in VT
modeling efforts to assess how changes in the oral and pharyngeal regions of the VT
alter speech acoustics; also assess the role anatomic growth plays in speech
intelligibility.
II. OBJECTIVE:
The purpose of this study is to determine comparability of APh
measurements against MRI measurements for both the oral and
pharyngeal portions of the VT.
III. METHODS:
Participants: Six adults (3
males, 3 females) between
the age of 22 years and 30
years participated in both the
APh and MRI components of
this study. Participants had
no health issues, specifically
no pathology in the head and
neck region including no
history of speech/language
or hearing difficulties. Also,
they had no
contraindications to undergo
an imaging study.
APh Protocol:
• Each participant exhaled into a mouthpiece by Eccovision® (Sleep
Group Solutions)5 attached to the APh wave tube in the supine
body position (to simulate MRI scanner table).
• The wave tube emitted a pulsing sound into the VT as the
participant exhaled. The acoustic pharyngometer then used the
reflected acoustic waves to calculate and display the cross-
sectional areas (CSA) of the VT as a function of distance from the
glottis to the teeth (pharyngogram).
• Each participant completed eight breathing trials. Four slow exhale
(inhale through nose, exhale through mouth) and four nasal
(inhale and exhale through nose). Graphs/pharyngograms
depicting the CSA were saved for each breathing trial.
• The slow exhale pharyngograms were used to make VT
length and volume measurements.
• The nose exhale pharyngograms were used to identify the
smallest CSA to mark the location of the oral-pharyngeal
junction (OPJ). The pharyngometer then used the OPJ to
calculate the oral and pharyngeal length and volume
measurements.
• APh waveforms were analyzed for both length and volume
measurements of the oral cavity, pharyngeal cavity and VT.
• The measurement definitions are as followed:
• Oral cavity length (OCL-APh: teeth to OPJ)
• Pharyngeal cavity length (PCL-APh: OPJ to glottis)
• VT length (VTL-APh: teeth to glottis
• The corresponding cavities’ volumetric measurements are:
oral cavity volume (OCV-APh), pharyngeal cavity volume
(PCV-APh), and vocal tract volume (VTV-APh).
I. BACKGROUND / INTRODUCTION
• Vocal tract (VT) measurements are typically made using medical
imaging studies such as X-ray radiography, magnetic resonance
imaging (MRI) and computed tomography (CT) scans. MRI is used
when detailed visualization of the soft tissue is needed, and
therefore optimal for making measurements of the oral and
pharyngeal regions of the VT.
• Acoustic Pharyngometry (APh) is a non-invasive technique that
uses the reflection of acoustic waveforms to calculate the cross-
sectional areas (CSA), length, and volume of the VT or upper
airway. Despite its long standing clinical use6 to assess patency of
the upper airway in sleep studies, a very limited number of studies
have examined APh measurements against actual anatomic
measurements; and such studies have only used select APh
measurements taken in the pharyngeal region (at the level of the
glottis and trachea or of the nasal cavity) to compare against
anatomic measurements obtained through MRI to confirm
comparability of measurements 1, 2, 3, 4, 7
Figure 1. Participant exhaling into the
Acoustic Pharyngometer wave tube while in
the supine body position. Measurements of
vocal tract length and volume were obtained
from the reflection of the acoustic
waveforms.
0
10
20
30
40
50
60
70
OCL PCL VTL OCV PCV VTV
Len
gth
(cm
)
M6004-28-09
APh Imaging Difference
0
10
20
30
40
50
60
70
OCL PCL VTL
Len
gth
(cm
)
0
10
20
30
40
50
60
70
OCV PCV VTV
Vo
lum
e (c
m3 )
Figure 2. Cross-
sectional areas (CSA)
of the oral-pharyngeal
cavity from APh (red)
and MRI (blue) as a
function of distance
from the glottis (0 on
the x-axis) for one
adult male participant.
The MRI (top) image
from the same
participant depicts the
corresponding
anatomic regions for
the CSAs.
MRI Protocol: Each
participant underwent a
MRI study in the supine
body position after
confirming that the APh
mouthpiece was in
place and their head
was in the neutral
position such that the
external auditory
meatus and shoulder
were horizontally
aligned, and the angle
between the
canthomeatal line and
orthogonal line was no
more than 18 degrees.
3D oral-pharyngeal model rendering:
• The posterior nasal cavity was set as the upper constraint while the opening of
the trachea was set as the lower constraint of the oral-pharyngeal or VT model.
• A set of 44 anatomic landmarks were digitally placed along the 3D VT model
using multiplanar visualization of the sagittal, coronal, and axial views of the
MRI study.
• The landmarks were then used to establish a path that represents the likely
pathway the APh waveform will take to travel through the VT. The path entailed
establishing an oral cavity (OC) path and a pharyngeal cavity (PC) path that
were created based on several landmarks and user-determined input, followed
by manual smoothing and interpolation.
• Findings from all six participants were similar to those of participant M6004
showcased in this poster.
• Figure 2 showcases that APh (red plot) trend is representative of the detailed
CSAs (blue plot) from MRI despite noted differences in actual measurements
where APh CSAs are noticeably larger than MRI.
• Figure 3 depicts the above noted observation where differences plotted in gray
highlight that APh can capture length measurements accurately, but tends to
inflate volumetric measurements particularly in the pharyngeal region.
Abstract: The size and shape of the mouth and throat contribute to the unique way each
person sounds. Acoustic Pharyngometry (APh) is a non-invasive technique that uses the
reflection of sound waves to measure the airway and assess its patency. To assess APh
measurements’ accuracy, we compared it against MRI measurements. Three men and
three women performed APh in the upright and supine body position and had MRI scans
in the supine body position. Findings revealed that length measurements were
comparable. However, APh cross-sectional areas and volumes were noticeably larger
than MRI. Although MRI measurements represent anatomic measurements more
accurately, APh does successfully capture the overall oral and pharyngeal measurements
and may be a useful method for the study of speech development and speech disorders.