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世 界 生 物 繁 育 技 术 的 先 驱37 38

实验室管理系统

SMILE 实验室管理系统人工授精（artificial insemination，AI）

人工授精大事纪：

是指利用器械以人工方法采集雄性家畜的精液，经检查、稀释、保存等特定处理后，用器械输入到雌性家畜

的生殖道的特定部位，使其妊娠的一种家畜繁育技术。

与自然交配相比，人工授精具有以下优点：

提高优良公畜配种效率

加速品种改良步伐，加快育种工作进程

有利于品种资源保护

防止疾病传播

克服公母家畜体格悬殊造成的交配困难

降低生产成本，提高经济效益

有利于提高母畜的受胎率

1780 年，意大利生理学家 Spallanzani 用处于体温温度的精液给 1只母狗人工授精并获得 3只小狗；

1899 年．俄国学者 Ivanoff 首次将人工授精技术运用到羊和家禽上；

1914 年，罗马大学的 Amantea 成功研制出世界上第一个狗假阴道；

20世纪三十年代，威斯康星大学的 Phillips 等人开发出了一种具有缓冲和营养作用的卵黄 -磷酸盐稀释液；

1937 年．丹麦兽医开发了母牛的子宫颈直肠把握输精法；

1946 年．法国卡苏创始人罗伯特·卡苏创立世界上第一个牛人工授精中心；

1951 年，英国人 Polge 利用甘油低温保存精液获得世界上第一头冷冻精液牛犊；

1957 年，美国育种服务组织（ABS）率先使用液氮作为制冷剂来冷冻和储存精液；

1963 年，法国 IMV 卡苏公司成立；

1964 年，罗伯特·卡苏发明世界上第一支精液细管；

20世纪 80 年代，法国 IMV 卡苏率先将先进的人工授精技术和产品带到中国

2011 年，法国 IMV 卡苏在中国成立全资子公司——上海卡苏生物科技有限公司