LeukemiaKali Cresent

1st HourOctober 5th, 2011

What is it? The rapid increase in

white blood cell count.

First called “Weisses Blut” by European Physicians

History Officially diagnosed in 1845 John Hughes Bennett Edinburgh 1913: 4 types diagnosed

History of treatment 3 types: Radiation,

Chemotherapy, and Arsenic.

Arsenic: Thomas Fowler – “Fowler’s Solution”

History of treatment Radiation: 1897 studies

found that radiation helped reduce tumors.

Chemotherapy: 1940s, Developed from Mustard Gas. ( Germans WW1)

Scientists John Hughes Bennett Thomas Fowler George Hitchings & Gertrude Elion

Foundations American Cancer

Society National Children’s

Cancer Society Me Fine Foundation

Folden, 2 yrs old

Testing

Physical Exam Blood Tests (CBC) Biopsy Spinal Tap X-Rays, MRI’s, etc.

Major Symptoms Poor blood

clotting Poor immune

system Anemia Lesions

Types of Leukemia

There are 4 main types of Leukemia.

Acute Lymphocytic Leukemia (ALL)

Chronic Lymphocytic Leukemia (CLL)

Acute Myelogenous Leukemia (AML)

Chronic Myelogenous Leukemia (CML)

Acute Lymphocytic Leukemia

Rapid multiplication

Childhood Leukemia

Ages 2-8 Easiest to treat Lymphocytes

Chronic Lymphocytic Leukemia

Slow multiplication 50+ Lymph nodes &

Spleen Lymphocytes

Acute Myelogenous Leukemia

Rapid Multiplication Granulocytes 40+

Chronic Myelogenous Leukemia

Slow multiplication Granulocytes Rare 30-60

Treatment Blood Transfusions Chemotherapy

(50+ drugs avail.) Radiation Bone Marrow

Transplants

Chemotherapy 3 stages 1st: Kills Leukemic cells as

quickly as possible. 2nd: Remission, destroys

any hidden cells 3rd: 2-3 years of more

drugs to kill remaining cells.

Radiation High-risk only! X-rays Stops cell division

Bone Marrow Transplants Only considered for CML,

AML, or relapsed ALL. Destroyed bone marrow

replaced with new. Helps produce healthy

blood. Given by needle

Blood Transfusions Increases RBC’s Keep hemoglobin

normal Maintain blood level Life-threatening

situations

Transmission/Inheritance Genetics Hereditary Environmental

Exposures

Demographics Any ethnicity, age,

gender, location Survival rates vary by

age Survival rates

percentage +

Bibliography http://rebeccanelson.com/leukemia/history.html http://cancer.about.com/od/leukemia/a/diagnos

eleukemi.htm http://

www.resource4leukemia.com/topics/foundationscharities.html

http://www.medicalnewstoday.com/articles/142595.php

Bibliography http://depts.washington.edu/drrpt/2002

/research/rare.html Leukemia by Alvin & Virginia Silverstein

& Laura Silverstein Nunn Leukemia by Dorothy Schainman and

David E. Newton