Kendall J. Bryant, Ph.D. , NIAAA Alcohol and AIDS Research National Institutes of Health
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Alcohol and AIDS: A New Decade
Grantsmanship Workshop XIX International AIDS Conference
Rome, Italy
Kendall J. Bryant, Ph.D. , NIAAAAlcohol and AIDS Research
National Institutes of Health
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NIAAA Vision Statement for prevention and treatment of HIV/AIDS
To support and promote the best science on alcohol and health:– Improving the diagnosis, prevention, and treatment of
alcohol use disorders to reduce new HIV infections and improve treatment outcomes
– Increasing the understanding of normal and abnormal biological functions and behavior relating to alcohol use and HIV infection
– Enhancing the quality of health and health care delivery in domestic and international settings to reduce morbidity and mortality
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Prevention of New Infections
• Multilevel Ecological Research• Behavioral Risk Reduction: High-risk groups, Social
Networks, and Concurrency, Event-Level Factors• Alcohol Interventions include Brief Motivational,
Cognitive Behavioral, and Pharmacotherapy in At-Risk Populations
• NIAAA FY2010 P01 Integrative Behavioral Prevention Research
• International HIV Prevention in Venue Based Settings (R01)
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Multilevel Models
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Alcohol Use: One of many issues in HIV+ patients life
Neurologic Effects
Immunologic Effects
Liver Damage
Depression
Substance Abuse
Treatment
HIV Treatment
Alcohol Use
Neuropathogenesis andPain ManagementHCV coinfection,HBV and chronic viral loadOther drugs Quality of LifeAccess to treatment
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NIAAA Portfolio : Funded 2010/11 Funded Initiatives
• Alcohol Pharmacotherapy for HIV+ • Centers for Integrative Research (P60, Consortiums)• Multilevel Preventive Interventions – Design and Testing• High-Risk Populations for Infection and Transmission:
Migrant Workers, Cross-Border Settings, Youth• Interagency Agreements for Collaborative Women and
Pediatric Cohorts• Developing International Networkers Alcohol HIV
Researchers• Targeted Initiatives: District of Columbia, Baltimore
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New Models for Studying Progression and Aging
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Implementation and Operations Research
• Develop Models of Interaction of Alcohol and HIV Prevention and Treatment Access and Uptake (and Comparative Effectiveness)
• Develop Models for Clinical Decision Making in Specific Settings for Patients, Providers, and Policy Makers
• Develop Identification, Screening, and Intervention Models (Seek, Test, and Treat) for Spectrum of Alcohol Use Disorders
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Algorithm for integrating alcohol screening and treatment into clinical care of HIV patients
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International Prevention