John Granton - Critical Care Canada Forum · PDF fileAm J Respir Crit Care Med. 2003...

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John Granton UHN, Mount Sinai and Women ’s College Hospitals FMD

Transcript of John Granton - Critical Care Canada Forum · PDF fileAm J Respir Crit Care Med. 2003...

Page 1: John Granton - Critical Care Canada Forum · PDF fileAm J Respir Crit Care Med. 2003 167(12):1633-40. Duggan et al, Am J Respir Crit Care Med 2003. Duggan et al, Am J Respir Crit Care

John Granton

UHN, Mount Sinai and Women’s College Hospitals

FMD

Page 2: John Granton - Critical Care Canada Forum · PDF fileAm J Respir Crit Care Med. 2003 167(12):1633-40. Duggan et al, Am J Respir Crit Care Med 2003. Duggan et al, Am J Respir Crit Care

Actelion

Bayer

United Therapeutics

GSK

Lilly

Pfizer

Ikaria

Page 3: John Granton - Critical Care Canada Forum · PDF fileAm J Respir Crit Care Med. 2003 167(12):1633-40. Duggan et al, Am J Respir Crit Care Med 2003. Duggan et al, Am J Respir Crit Care

Review the diagnosis and classification of PH

Understand the importance of a thoughtful hemodynamic approach

Improve understanding and relevance of PH in my ICU practice

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I

II

III

IV

Page 5: John Granton - Critical Care Canada Forum · PDF fileAm J Respir Crit Care Med. 2003 167(12):1633-40. Duggan et al, Am J Respir Crit Care Med 2003. Duggan et al, Am J Respir Crit Care

That which does not kill me postpones the inevitable

RV failure

Page 6: John Granton - Critical Care Canada Forum · PDF fileAm J Respir Crit Care Med. 2003 167(12):1633-40. Duggan et al, Am J Respir Crit Care Med 2003. Duggan et al, Am J Respir Crit Care
Page 7: John Granton - Critical Care Canada Forum · PDF fileAm J Respir Crit Care Med. 2003 167(12):1633-40. Duggan et al, Am J Respir Crit Care Med 2003. Duggan et al, Am J Respir Crit Care
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PVR problem

Page 10: John Granton - Critical Care Canada Forum · PDF fileAm J Respir Crit Care Med. 2003 167(12):1633-40. Duggan et al, Am J Respir Crit Care Med 2003. Duggan et al, Am J Respir Crit Care
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CHEST 2011; 140(1):34–41

Pulmonary compliance = SV / ΔP

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Circulation. 2012;125:289-297

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Circulation. 2009;119:2663-2670

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Exercise Hemodynamics Enhance Diagnosis of Early Heart Failure With Preserved Ejection Fraction.Borlaug, Barry; Nishimura, Rick; Sorajja, Paul; Lam, Carolyn; Redfield, Margaret

Circulation: Heart Failure. 3(5):588-595, September 2010.DOI: 10.1161/CIRCHEARTFAILURE.109.930701

Figure 1 . PCWP increased to a greater extent in HFpEF compared with NCD with leg elevation and during exercise (A). PCWP returned to baseline almost immediately in recovery. LVEDP (B) and mean PAP (C) also rose with exercise more dramatically in the HFpEF group (P for exercise change between groups).

NCDHFpEF

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Crit Care Med 2012; 40:1539–1545

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CCM 2001; 29:1154 –1158

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Am J Respir Crit Care Med. 2003 167(12):1633-40

http://www.thoracic.org/index.cfm
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Duggan et al, Am J Respir Crit Care Med 2003

Page 23: John Granton - Critical Care Canada Forum · PDF fileAm J Respir Crit Care Med. 2003 167(12):1633-40. Duggan et al, Am J Respir Crit Care Med 2003. Duggan et al, Am J Respir Crit Care

Duggan et al, Am J Respir Crit Care Med 2003

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Ann Surg 2008;247: 617–626

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semio - curs3 respir

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American Thoracic Society/European Respiratory … › statements › resources › respmuscle.pdfAmerican Thoracic Society/European Respiratory Society Am J Respir Crit Care Med Vol

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American Thoracic Society/European Respiratory SocietyAmerican Thoracic Society/European Respiratory Society Am J Respir Crit Care Med Vol 166. pp 518–624, 2002 DOI: 10.1164/rccm.166.4.518

American Thoracic Society/European Respiratory SocietyAmerican Thoracic Society/European Respiratory Society Am J Respir Crit Care Med Vol 166. pp 518–624, 2002 DOI: 10.1164/rccm.166.4.518

American Thoracic Society PATIENT EDUCATION | …What is Pneumonia? Adapted from “What is Pneumonia” Am J Respir Crit Care Med Vol. 193, P1-P2, 2016. Authors: Drs. Barbara Jones,

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Mechanical Ventilation in Acute Respiratory Distress Syndrome · Papazian L, et al. Crit Care Med 2005;33:2162 Mancebo J, et al. Am J Respir Crit Care Med 2006;173:1233 Demory D,

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