ISHI APHIA CON 2021

ISHI APHIA CON2021

Indian Society for Histocompa�bilityand Immunogene�cs (ISHI)

&Asia-Pacific Histocompa�bility

and Immunogene�cs Associa�on (APHIA)

For furth

er info

rmatio

n visit: w

ww.ishi-a

phia2021.com

th th17 -20

November 2021

Virtual Conference

Theme : MHC, Transplantation & Beyond

Conference Supported By:

SCIENTIFIC PROGRAM




Welcome Message

We are pleased to announce that the "ISHI APHIA CON 2021", a joint meeting of the Indian Society for Histocompatibility and Immunogenetics (ISHI) and Asia-Paci�c Histocompatibility and Immunogenetics Association (APHIA) will be held Virtually from November 17 to 20, 2021.

In view of the huge time difference between APHIA member states, it has been decided to commence the activity at 8AM India standard time each day which corresponds to10.30AM for Singapore and Perth and 1.30PM for Melbourne. The organizing committee will request the speakers for their pre-recorded lectures so that participants from Gold Coast, New Zealand and other areas could listen to these at their convenience.

A galaxy of well-known international names including those from within India will address the conference. This will be a great opportunity for young researchers, immunologists, geneticists, transplant physicians and surgeons, pathologists and technologists to expose themselves to the fundamentals of the HLA system including its clinical role so as to maximize interest, knowledge retention and skill development.

For further details and online registration, visit our website: www.ishi-aphia2021.com

Dear All,

Warm wishes and sincere regards,

The main theme of the conference is "MHC, Transplantation and Beyond". A one-day Technology Workshop and APHIA Quality Assurance Program will precede the three-day joint meeting which will take place from Nov 18 to 20. Participants from the Asia-Paci�c region, neighboring countries around India, the gulf region and those from various states of India will attend the conference. We expect close to 200 attendees representing all major HLA and transplant centers in the region.

Organising CommitteeISHI APHIA CON 2021

Once again we extend cordial welcome to you all and look forward to your active participation.




Organising Commi�ee

Prof. (Dr.) Narinder Kumar MehraOrganizing Chairperson

President, ISHI

Dr. Uma KangaOrganizing Secretary

Secretary, ISHI

Dr. Varsha TrivediOrganizing Secretary

Dr. Heather DunckleyPresident, APHIA

Dr. Gaurav SharmaJoint Organizing Secretary

Dr. Yoginder Pal SinghTreasurer

Dr. Arishma LataSecretary, APHIA




Virtual Conference

ISHI APHIA CON 2021th th

17 -20 November 2021

Day 1 - 17 Nov (Wednesday)

Auditorium

Time Topic Speaker Time Zone

0800-0810 NETWORKING

0810-0825 INAUGURATION

0810-0815 Lamp Ligh�ng Ceremony

0815-0825 Welcome Address by Narinder K Mehra (President, ISHI) & Heather Dunckley (President, APHIA)

0830-0910 Prof. Narinder Mehra Ora�on

0830-0835 About the Ora�onUma Kanga Secretary, ISHI

0835-0840 Introduc�on of the Speaker Narinder K Mehra President, ISHI

0840-0910 Immunogene�cs of Hematopoie�c Stem Cell Transplanta�on Effie Petersdorf Sea�le, Washington, USA

19:10 CST Tue, 16 Nov 2021

0915-1115 Session I

Moderators: Heather Dunckley (New Zealand), Jyo� Bajpai (India)

0915-0940Human Natural Killer Cells: Basic Biology and Clinical Applica�ons Duarte, California,USA

Michael A. Caligiuri19:45 PST Tue, 16 Nov 2021

0940-1005Becoming A Donor Selec�on Wizard: Priori�za�on Guidelines By HCT Source

Medhat Askar Dallas, Texas, USA

22:10 CST Tue, 16 Nov 2021

1005-1030Impact of COVID-19 & Pre-transplant immune monitoring in renal transplanta�on

Narinder K Mehra New Delhi, India

1030-1055Gene�cs and Immunological study of SARS-CoV-2 pa�ents and Vaccinee in Thailand

Na�ya Hirankaran Bangkok, Thailand

12:00 ICT

1055-1115 Discussion and Interac�ve Session

1115-1215 BREAK

1215-1410 Session II

Moderators: Ashraf Dada (Saudi Arabia), Meenakshi Singh (India)

1215-1240 Effect of HLA-A expression on Infec�ous DiseasesSouth AfricaVeron Ramsuran

08:45 SAST

1240-1305An emerging role of the HLA immunopep�dome in hematopoie�c cell transplanta�on

Katharina Fleischhauer Essen, Germany

08:10 CET

1305-1330HLA-C an important player in the immune regula�on of pregnancy

Frans HJ Claas Leiden, The Netherlands

08:35 CET

1330-1355 New Targets for Leukaemia and Immuno-Modula�onAlejandro Madrigal London, UK

08:00 GMT





Virtual Conference

ISHI APHIA CON 2021th th

17 -20 November 2021

Day 2 - 18 Nov (Thursday)

Auditorium


0800-0900 Session III

Moderators: Lloyd D’Orsonga (Australia), Ajay Baranwal (India)

0800-0825The best way to deal with DSA and HLA mismatch is to avoid it: expanding the role of kidney exchange

Dorry Segav Bal�more, USA

21:30 EST Wed, 17 Nov 2021

0825-0850 Molecular Mismatch Approaches for Transplanta�onAnat Tambur Chicago, USA

20:55 CST Wed, 17 Nov 2021


0900-0930 BREAK

0930-1130 Session IV: Oral Presenta�ons (8min + 2min)

Moderators: Brian Tait (Australia), Gurvinder Kaur (India),Latha Jagannathan (India)

Abstract No. Abstract Title Name Time Zone

14Single an�gen bead assay for detec�on of donor specific an�bodies in renal transplant recipients : 2 years experience from South India

Mamidi NeerajaHyderabad, India

38 Valida�on of allele level high resolu�on KIR typing Selma Zenia Dsilva Mumbai, India

40Incidence of acute gra� versus host disease in matched related and mismatched related bone marrow transplant in thalassemia

Aarushi Mi�alJaipur, India

41Can we predict the risk of azathioprine induced pancrea��s in pa�ents with inflammatory bowel disease (IBD) by the HLA associa�on

Rajeshwari Basavanna Mumbai, India

49Pre-emp�ve kidney transplanta�on from deceased donors in Western Australia: A review of recipient outcome

Lloyd D'Orsogna Perth, Australia

12:50 AWST

57

Risk stra�fica�on of screening tests like flow cross-match (FCXM) and an�-HLA an�body screen (HAS) calculated on the basis of mean fluorescence intensity (MFI) of luminex single an�gen bead (SAB) assay: Single center report

Simmi MehraGurgaon, India

59A rare case of an�-U an�body alloimmuniza�on in antenatal pa�ent

Vidisha PayalJaipur, India

84 Resolving ambigui�es of HLA typing by sequence-specific oligonucleo�de probe (SSOP) method using sequence-specific primer (SSP) method

Poonam Kumari Gurgaon, India

1130-1200 BREAK

1200-1330 Session V

Moderators: Dolly Daniel (India), Jane�e Kwok (Hong Kong)

1200-1225 Challenges in implemen�ng Virtual crossmatching in SOT workRhonda Holdsworth Melbourne, Australia

17:30 AEDT

1225-1250 Indirect recogni�on of HLA in solid organ transplanta�onEric Spierings Utrecht, The Netherlands

07:55 CET

1250-1315Convenient HLA Typing & Automated An�body solu�ons for solid organ transplanta�on

Kris�n Launhardt Berlin, Germany (BAG Speaker)

08:20 CET


1330-1340 BREAK

1340-1500 General Body Mee�ng – ISHI




Virtual Conference

ISHI APHIA CON 2021th th17 -20 November 2021

Day 3 - 19 Nov (Friday)

Auditorium


0800-0900 Session VI

Moderators: Narinder K Mehra (India) , Ritu Aggarwal (India)

0800-0825HLA and Disease associa�ons examined by NGS unravel func�onal allele features applied to transplanta�on matching

Marcelo Fernandez-Vina Stanford, California, USA

18:30 PST Thu, 18 Nov 2021

0825-0850Capture enrichment-based NGS for HLA typing: li�ing the limita�ons of long-range PCR approach

Raja Rajalingam San Francisco, USA (CareDx Speaker)

18:55 PST Thu, 18 Nov 2021


0900-0930 BREAK

0930-1130 Session VII : Oral Presenta�ons (8min + 2min)

Moderators: Lyanne Weston (Australia), Ram M Jaiswal (India), Gaurav Sharma (India)


24Infec�ous complica�ons and outcome a�er allogenic hematopoe�c stem cell transplanta�on

Jaipur, IndiaBhanupriya Sharma

28HLA profile of the Indian Kami popula�on shows a close gene�c affinity with the North Indian Indo-Aryan popula�on Sikkim, India

Bisu Singh

35Haploidentical Hematopoetic Stem Cell Transplantation in Paediatric Patient Population with Positive Lysate Crossmatch- A Case Series In A Limited Resource Setting

Deepali NakerMumbai, India

37HLA Class I and Class II allele frequencies in Indian popula�on Manisha Tambe

Mumbai, India

39Long non coding RNAs as molecular signatures for acute renal allogra� rejec�on

New Delhi, IndiaAkanksha Sharma

45ISO/IEC17043:2010 accredited EQAS : An analy�cal approach to handling discordant observa�ons

Vanshika JainNew Delhi, India

58Real World data on rela�onship of donors (with their pa�ents) and tests performed for suppor�ng claimed rela�onship in living-donor kidney transplant se�ng: Single–center report

Rajni ChauhanGurgaon, India

69 HLA matching (HM) score vs. Mismatch (MM) score Jharkhand, IndiaGopal Sonai Muthu

71Nanopore sequencing data analysis using cloud compu�ng service

Linh TruongPerth, Australia

13:10 AWST

1130-1200 BREAK

1200-1400 Session VIII

Moderators: Dunia Jawdat (Saudi Arabia), Rajni Rani (India)

1200-1225HLA genes as markers of demographic and selec�ve processes in human evolu�on

Alicia Sanchez-Mazas Geneva, Switzerland

07:30 CET

1225-1250 MIC genes: ge�ng close to the clinicSeiamak Bahram Strasbourg, France

07:55 CET

1250-1315In phase polymorphism analysis of HLA mini genome : exploring gene�c diversity among Indians

Uma Kanga New Delhi, India





Virtual Conference

ISHI APHIA CON 2021th th17 -20 November 2021

Day 4 - 20 Nov (Saturday)

Auditorium


0800-0930 Session IX

Moderators: Jonathan Downing (Australia), Varsha Trivedi (India)

0800-0825 HLA in Cancer, or Drug Reac�ons 1William Hildebrand Oklahoma City,USA

20:30 CST Fri, 19 Nov 2021

0825-0850Non-HLA An�body Panel Discovery, Development, and Valida�on: From Bench to Bedside

Carrie L. Butler California,USA (Immucor Speaker)

18:55 PST Fri, 19 Nov 2021


0900-0915 BREAK

0915-1100 Session X : Virtual Poster Discussions

Moderators: Anil Handoo (India), Sally Elfishawi (Egypt), Monica Jain (India)


15

Frequency of HLA alleles by next genera�on sequencing method among lung transplant recipients with inters��al lung disease and post COVID-19 lung fibrosis: Single centre report in South India

Rohit IyyapuHyderabad, India

34DRB1-DQB1-DQA1 haplotype analysis in random popula�on from Mumbai

Suchita JogaleMumbai, India

41U�lity of mul�ple pla�orms to detect an�-HLA donor specific an�bodies and improve renal transplants outcome

Rajeshwari Basavanna Mumbai, India

42Gene�c associa�on of IL-18 SNP -607C/A with type 1 diabetes in North India

Aakansha PathakNew Delhi, India

43Characteriza�on of GAD65 epitopes possibly presented by type 1 diabetes associated HLA-DR3 and/ or DQ2 molecules New Delhi, India

Neihenuo Chuzho

44Allele and haplotype frequencies of 11 HLA loci in 339 Koreans using next-genera�on sequencing

Kiwook JungSeoul, South Korea

13:15 KST

52A longitudinal study of innate immune cell profiles of covid-19 a�er recovery Nonthaburi, Thailand

Vichaya Ruenjaiman11:20 ICT

53 An unveiled TIGIT muta�on in a THAI severe COVID-19 pa�ent Bangkok, Thailand

Pimpayao Sodsai11:25 ICT

56The inhibitory effect of enoxaparin on plasma-induced neutrophil extracellular traps from COVID-19 pa�ents with severe pneumonia

Supichcha SaithongBangkok, Thailand

11:30 ICT

57Prospec�ve study to analyze pre-transplant compa�bility algorithm for live-related donor kidney transplant in Indian se�ng - Single center report

Simmi MehraGurgaon, India

60 Possibility of non-consanguineous parent being a full matched prospec�ve donor for pa�ents undergoing HSCT Mumbai, India

Jyo� Rajak

78 Immunogene�c interac�ons of HLA (C1/2) and KIR genes among scleroderma pa�ents from Western India Mumbai, India

Alok Kumar Tembhurne

85Effect of presence of pre-transplant donor specific HLA-an�bodies on kidney transplant outcome

Lekha RaniChandigarh, India

144Distribu�on of pharmacogenomically relevant HLA alleles in two defined ethnic groups from North India

Abhishweta Saxena Varanasi, India

1100-1130 BREAK

1130-1300 Session XI

Moderators: Ranjana Minz (India), Yoginder Pal Singh (India)

1130-1155The Next Next Genera�on: Rapid High resolu�on HLA typing on the Oxford Nanopore Technology pla�orm

Dianne de San�sPerth, Australia

14:00 AWST

1155-1220Towards Con�nuous Improvement in Turnaround Time (TAT): Experience With The New MiaFora Express So�ware

Chandramouleeswaran Chennai, India (Immucor Speaker)

1220-1245Latest Best-in-Class NGS based solu�ons for Transplant Diagnos�cs & Monitoring

Maarten Penning The Netherlands (GenDx Speaker)

07:50 CET


1300-1320 18IHIWSSebas�aan Heidt

Eric Spierings

The Netherlands

& The Netherlands

08:30 CET

1300-1345 Closing

Oral/Poster presenta�on Awards announcements &

Organizing Secretaries

Uma KangaSecretary, ISHI

Varsha Trivedi

Closing remarks

(President, APHIA)

Narinder K Mehra

&(President, ISHI)

Heather Dunckley

Vote of Thanks

(Secretary, APHIA)

Gaurav Sharma(Jt. Org. Secretary)Arishma Lata

Conference Secretariat56, Institutional Area, Sector - 44, Gurugram-122002, Haryana, India

Mr. Manas R. Dash | Mob: +91 70084 27610 | Email: [email protected]

ISHI APHIA CON 2021

Documents

Transcript of ISHI APHIA CON 2021