Inward Rectifying K + Current Fast Na + Current

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Inward Rectifying K + Current Fast Na + Current Naralys B. Rukhinda M. Girish R.

description

Inward Rectifying K + Current Fast Na + Current. Naralys B. Rukhinda M. Girish R. Ion Current Dynamics. Avia Biosciences, .  Currents in Action Potential . N.d . n.p . Web. 24 Jan 2013. . ten Tusscher Equations For Ion Channels . - PowerPoint PPT Presentation

Transcript of Inward Rectifying K + Current Fast Na + Current

Page 1: Inward Rectifying K +  Current Fast Na +  Current

Inward Rectifying K+ CurrentFast Na+ CurrentNaralys B. Rukhinda M. Girish R.

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Ion Current Dynamics

Avia Biosciences, . Currents in Action Potential. N.d. n.p. Web. 24 Jan 2013. <http://avivabio.com/products/tutorephys.php>.

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ten Tusscher Equations For Ion Channels

“m is an activation gate, h is a fast inactivation gate, and j is aslow inactivation gate. Each of these gates is governed by HodgkinHuxley-type equations.”

“x K1. is a time-independent inward rectification factor that is a function of voltage. Ko/5.4 represents the Ko dependence of the current.”

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First Run Results:

Spiral Waves

Inward Rectifying K+ Current

Fast Na+ Current

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First Run Results:Tip Trajectories

Inward Rectifying K+ Current

Fast Na+ Current

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Increasing INa and IK1

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Keeping INa at 25%

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Keeping INa at 185%

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Keeping IK1 at 185%

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Second Run Results:Spiral Waves

PETER!!!!!

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Second Run Results:Tip Trajectories