INTERPRET - 1 Voxel localized spectrum Metabolic image Morphological image Pixel profile Nosologic...

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INTERPRET - 1 Voxel localized spectrum Metabolic image Morphological image Pixel profile Nosologic image Classification Color code Overview
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Transcript of INTERPRET - 1 Voxel localized spectrum Metabolic image Morphological image Pixel profile Nosologic...

Page 1: INTERPRET - 1 Voxel localized spectrum Metabolic image Morphological image Pixel profile Nosologic image Classification Color code Overview.

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Voxel localized spectrum

Metabolic imageMorphological image

Pixel profile

Nosologic image

ClassificationColor codeOverview

Page 2: INTERPRET - 1 Voxel localized spectrum Metabolic image Morphological image Pixel profile Nosologic image Classification Color code Overview.

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When entering the software…

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For raw processing:

a set of default parameters is

proposed

Depending on the echo-time

(136 or 272 ms)

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During the raw processing, information is displayed for the successive steps

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The morphological image and a spectrum (real for 136 ms, magn for 272ms TE) are displayed

Page 6: INTERPRET - 1 Voxel localized spectrum Metabolic image Morphological image Pixel profile Nosologic image Classification Color code Overview.

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Next step is constructing the Metabolic images from the area of each peak

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Default parameters are proposed for the line fitting

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Spectra from the voxels in and around the VOI are then fitted

Constraints:- negative peaks for lactate and alanine- same linewidth

To add:- chemical shift constraints

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All metabolic images are reconstructedThe clinician may visualize the different metabolic images to control the fitting process

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For each voxel, the fitted spectrum can be overplot on the raw data

Erroneous fitting can be corrected, voxel by voxel

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Next step is constructing the Nosologic image

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What next ?

◊ Classification process (metabolites at 136 ms TE + water information) In progress - by Isabel Brito

◊ Improve pre-processing HLSVD Remove artefact from deconvolution process Baseline correction

◊ C-programming + Java interface In progress - by Blandine Chanteloup

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The metabolic images are interpolated

The user has to draw an ROI in the healthy tissue on the water T2

image

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From the 6 metabolic maps and the water information,

a profile is calculated for each pixel

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The nosologic image is computed and displayed

For each pixel, the highest belonging degree is color encoded

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Data may be printed, saved, or the clinician may load a new patient exam

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The default morphological image may be changed…

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Information is available on the different step results