Infection-The Last Bony Frontier

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    OR=sacred place of trust?deserves our best efforts

    INFECTION CONTROL

    Critical for the Success of Surgery

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    the COST to the hospital (Nepean-500 cases@yr.)

    to the economy-Aust $300M@ yr., AUD

    20,000/patient) The additional cost imposed on the US health system

    annually by antibiotic resistance has been estimated to

    range between US $100 million and US $30 billion.[Hellinger WC, Confronting the problem of Increasing Antibiotic

    Resistance, South Med J 93(9): 842-848, 2000

    MRSA

    learn to live with it

    (MRSA and beyond. Marshall et al. ANZ JSurg 2004 74: 465-469)

    -suggested hand washing and nasal mupirocin

    or GET RID OF IT

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    Sterile(Operating)ZoneKey Concept

    = area between incision&surgical team

    - the surgical workplace

    - must be ultraclean

    build(wash/gown/drape)

    maintain (intra-op)dismantle (?after you leave the OR)

    Challenge to:

    restructure whats already there Looked at:

    - hand wash

    - mask

    - gloving

    - gowning

    - draping

    - handling the scalpel-

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    yeS-WIPEyour handsnaturally

    SQUEEZE

    WASH

    DRY

    Clinical Results

    Soap & Water: 90% clean hands

    reproduced the surgical scrub with

    yeS-Wipe (72cc device replaces sink area);

    >99% saving on:water,soap and space

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    Gowning- violations related to final flap tie

    -

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    Multi-Centre Clinical trial

    Sydney March 2000

    5 x Hospitals (Development of a new

    surgical gown: a multicenter study. Surg Today. 2006;36(5):490.

    200 gowns tested

    Faster to don in 75%(90%)

    Remained closed 92%(vs. 8%)(100%)

    Infection control improved 75%(82%)

    Use again 70%(100%)

    i.e.. Faster to don/remains closed/infection

    Draping

    - 100 cases examined

    - 4 violations of sterile technique

    (one major) per operation

    - slow

    - surgeon & scrub dependent

    Challenge:Make easier & free surgeon & scrub to work

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    Scalpel Blade Pick-up

    - slow/dangerous

    Challenge:

    - make easier and faster

    - met

    S-Foam

    S-Foam

    An ImportantInfection ControlDevice......for the safe and efficient handling of sharps in the Operating Theatre

    Low Tack Adhesive-Leaves noResidue

    Easy Peel- Backing Paper

    V- Shaped Slot- Provides Added Grip

    Blade End Down

    Large Tactile Body For

    Easy Blind Location, Also forScraping Debris Off Blade

    Handle End Up

    TMScalpel Held Perpendicular toBottom of Dish- Easy Pick Up

    Designed and Made in Australia Distributed & Packaged by DEFRIES INDUSTRIES Patent Pending

    Available in SterilePackaging

    NEW

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    id.Sid.S

    old

    crowded

    id.S(2)

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    id.S(2)

    Phytochemicals

    -plant derived substance with active

    hydrocarbons for :

    antisepsis(high MRSA activity)

    wound healing problems

    biological sealant(tissue healing problems)

    treatment of TB/Malaria

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    Phytochemical papers

    Sherry E, Warnke PH, Boeck H.

    Percutaneous treatment of chronic MRSA osteomyelitis with a novel plant-derived antiseptic.

    BMC Surg. 2001;1(1):1. Epub 2001 May 16.

    Sherry E, Boeck H, Warnke PH

    Topical application of a new formulation of eucalyptus oil phytochemical clears methicillin-resistant

    Staphylococcus aureus infection.Am J Infect Control. 2001 Oct;29(5):346. No abstract available.

    Sherry E, Warnke PH.

    Alternative for MRSA and Tuberculosis (TB): Eucalyptus and Tea-Tree Oils as New Topical

    Antibacterials

    AAOS, Dallas.Feb 2002 Sherry E , Warnke PH, Boeck H.

    Sherry E, Sivananthan S, Warnke PH, Eslick G.

    Topical phytochemicals used to salvage the gangrenous lower limbs of type 1 diabetic patients.

    Diabetes Res Clin Pract. 2003 Oct;62(1):65-6. No abstract available.

    Phytochemical papers (ctd)

    Warnke PH, Terheyden H, Acil Y, Springer IN, Sherry E, Reynolds M, Russo PA, Bredee JP,

    Podschun R. Related Tumor smell reduction with antibacterial essential oils.Cancer. 2004 Feb 15;100(4):879-880.

    E Sherry , PH Warnke

    Successful use of an inhalational phytochemical to treat pulmonary tuberculosis: A case report.

    Phytomedicine vol 11/issue 2-3, Feb.,p95. 2004.

    Antibacterial essential oils reduce bad smell in cancer patientsP.H. WARNKE1, E. SHERRY2, R. PODSCHUN1, H. TERHEYDEN1, Y. ACIL1, and I.N.SPRINGER1, 1 University of Kiel, Germany, 2 University of Sydney, Penrith, Australia. 4026

    The IADR/AADR/CADR 82nd General Session (March 10-13, 2004)

    Honolulu, HI

    E Sherry S Sivananthan PH Warnke Inhalational phytochemicals to treat pulmonary tuberculosis;

    tyo case reports AJIC Oct 2004

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    MRSA case

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    Tumour work

    Papers- Palliative CareSINUS

    Further tumour/pallaitive care work

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    Papers-TB

    28F, first case

    Treatment costs around US $2500 per patient,

    rising to US $250,000 in multi drug resistant TB,

    with the overall potential cost of lost productivity due to

    TB is in the order of 4%-7% of GDP

    new era of...

    local treatment with:

    debridement & local antiseptic

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    the new OR:

    -yeS-WIPE Surgical Scrub-S-Gown Gowning

    -id.s Draping

    -new masks clean air-phytos to seal wound

    But need to CONVINCE industry?????????to make all these changes

    Basics:Basics:

    Swedish Hip Registry, 2003Swedish Hip Registry, 2003

    Critical issues are:Critical issues are:

    -surgical technique- OPTIMIZED-surgical technique- OPTIMIZED

    -implant design- NO CHANGE-implant design- NO CHANGE

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    vol=(1/3(r2)(height)

    -

    ? < 4% soft tissue problems? < 4% soft tissue problems

    -Assume-Assume conecone of dissection;of dissection;

    vol=(1/3(r2)(height)vol=(1/3(r2)(height)

    -Then-Then 5 cm versus 255 cm versus 25cm incisioncm incision

    means 1/25 volume ofmeans 1/25 volume of

    soft tissue traumasoft tissue trauma

    and ?

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    Strategy

    -reduce size frontier(incisi-in vivo tissue engineering(

    -surgeon in control