Importance of vitamin d in orthopaedic patients
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Importance of Importance of Vitamin D In Vitamin D In
Orthopedic PatientsOrthopedic Patients
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OSTEOPOROSISOSTEOPOROSIS
is highly prevalent, affecting approximately
one-third of women aged 60-70 years, and
two-thirds of those aged 80 years and older
200 MILLION WOMEN 200 MILLION WOMEN
WORLDWIDEWORLDWIDE
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OSTEOPOROSISOSTEOPOROSIS is the major cause of
FRACTURESFRACTURES
1992;7:1005-10
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40% OF WOMEN40% OF WOMEN and 13% of men
aged 50 years and older will sustain an
OSTEOPOROTIC FRACTUREOSTEOPOROTIC FRACTURE
in their remaining lifetime
1992;7:1005-10
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FRACTURESFRACTURES have a profound impact on
QUALITY OF LIFEQUALITY OF LIFE.
Approximately 20%-25%20%-25% of women over age 50
years have had one or more
VERTEBRAL FRACTUREVERTEBRAL FRACTURE, the
most common osteoporotic fracture
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Both vertebral and hip fractures are associated with excess
mortality. For instance, approximately 20% OF 20% OF
HIP FRACTURE PATIENTSHIP FRACTURE PATIENTS
aged 50 years and older
DIE WITHIN 1 YEARDIE WITHIN 1 YEAR
2001;285:320-3
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Patients being treated for
OSTEOPOROSISOSTEOPOROSIS should
be adequately supplemented with
calcium and VITAMIN DVITAMIN D to
maximize the benefit of treatment
2007;24(12):1017-29
Drugs & Aging Drugs & Aging
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Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
INCREASED INCREASED
RISK OF FALLSRISK OF FALLS
2004;291:1999-2006
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Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
FALLS-RELATED FALLS-RELATED
FRACTURESFRACTURES
2003;18:343-51
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Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
HIGHER RISK FOR HIP HIGHER RISK FOR HIP
FRACTUREFRACTURE
2008;149:242-250.
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VITAMIN D RECEPTORSVITAMIN D RECEPTORS
(VDRs) are known to be present in
muscle tissue.
2001 Jan;33(1):19-24.
The Histochemical JournalThe Histochemical Journal
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Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
AGE-RELATED MUSCLE AGE-RELATED MUSCLE
WEAKNESSWEAKNESS
1986;7:434-8
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Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
MUSCULOSKELETAL MUSCULOSKELETAL
PAINPAIN
2003;78:1463-70
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Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
CHRONIC LOW BACK PAINCHRONIC LOW BACK PAIN
2003 Jan 15;28(2):177-9
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Studies have also demonstrated a correlation between
LOW SERUM VITAMIN DLOW SERUM VITAMIN D
&
INCREASED INCREASED
BODY SWAYBODY SWAY
2001;109:87-92
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Lower concentrations of 25(OH)D
are associated with significant
BACK PAINBACK PAIN in older women
2008 May;56(5):785-91.
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Vitamin D deficiency is now
recognized as a PANDEMIC PANDEMIC
2008 Apr;87(4):1080S-6S.
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VITAMIN DVITAMIN D Reduced the
RISK OF FALLSRISK OF FALLS by More Than
20%20% Among Elderly Populations
2004;291:1999-2006
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100 000 IU100 000 IU VITAMIN DVITAMIN D33 every 4
months was safe and effective in decreasing the
incidence of
OSTEOPOROTIC FRACTURESOSTEOPOROTIC FRACTURES
by by 33%33% compared with placebo
2003 Mar 1;326(7387):469.
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Repletion of VITAMIN DVITAMIN D and at
the Time of Fracture May Reduce
Future Fracture Risk and
FACILITATEFACILITATE
HIP FRACTURE REPAIRHIP FRACTURE REPAIR
1999;281:1505-1511.
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A single high dose of VITAMIN VITAMIN
D3D3 stimulated
FRACTURE HEALINGFRACTURE HEALING
1997;116(1-2):37-40.
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CHOLECALCIFEROL CHOLECALCIFEROL (100 000 IU) is a safe, effective, and
simple way to increase calcidiol
concentrations
Vol. 87, No. 3, 688-691, March 2008.
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Oral / IM Ampoule
Containing
5mg Cholecalciferol eq to 200,000 IU Cholecalciferol
Light Resistant Ampoule Packaging
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Dose
1 Ampoule (200,000 IU)
every 6 months
Elderly
1/2 Ampoule (100,000 IU)
every 3 months
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Thank You