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Trng THPT NGUYN THNG______________***______________

BIN SON: NGUYN QUC TUN

____________________________________________________________________

H & TN:!"P:

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Trng THPT NGUYN THNG______________***______________

#T$I B%N !N TH' NHT(

BIN SON: NGUYN QUC TUN

____________________________________________________________________

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LI NI U:

T)I !IU CH+ ,- C.P T"I C$C CNG TH'C T/NH TO$NHU NH0 1HNG ,- C.P T"I !/ THUY2T3

C g sai st xin cc bn thng cm & chnh sa gim!

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CHNG 1: ESTE1. CNG THC CU TO:

* 4567 89n ; RCOOR`?@A R` H* 4567 n 89n ;? H@CAa) P THY PHN:

Z 6rng 6 H[:a RCOOR`bH2O

+ \QH c RCOOH /R`OH

[ ] [ ][ ] [ ]!"

#a

"#

OH$$COOH

OH$COO$%

]

^

] =

c RCOOH /R`OH + \QH

a RCOOR`bH2O " B% st ha#

[ ] [ ][ ] [ ]#a

!"

"#

OH$COO$

OH$$COOH%

^

]

]]

= ]

M

"#

"#%

% =

&& CH' (:NLE n@ 6; ;9A 6;` 5a 6rng ng 6;

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st " *aOH4 H2O# " m89i *a4 axit cacbxy'ic# anc' 7567 n

st " *aOH4 H2O# " m89i *a4 axit cacbxy'ic# an/hit 7567: COOsCHI]s

st " *aOH4 H2O# " m89i *a4 axit cacbxy'ic# xtn 7567: COOsCR``I]s ?@A ]]b;F H

st 2*aOH 2 m89i H2O

7567 p= i;7n ?J 8tng 8ung p= i;7n: COOsCvHwssst " *aOH4 H2O# J sB /8y nhKt 7567 ?xng 89n ;NG TON 9T9: xc Nnh s9 nhm ch%c st " #A

/0/

NaOH?-

)

)= # 6r} 7567 p= i;7n ?J 8tng 8ung p= i;7n(

n*aOH c7nP 2$nst#7567 i< ;L6( 7567 89n ;

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TH^: ^ 7567 Vng ]: MCOO]& COO]

E hh 2 chKt hT8 c1 N1n ch%c *aOH Jm89i 2anc' N1n ch%c THM: M=n[ M 7567: ]OH & COO]

TH^: ^ 7567 Vng : COO]& COO]]

st Na ch%cAE L% st ha giTa axit 5Mi anc' " B% Uhng hVn tVn#A

o |n 8= ;

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CHSCH2COOH: =A6 iriAnA CHSCH"CHS#COOH: =A6 A5E6ArA CHSCH2CH2CH2COOH: =A6 ?=7rA CHSCH"CHS#CH2COOH: =A6 A5?=7rA CH2ICHCOOH: =A6 =r>A CH2IC"CHS#COOH: =A6 76=r>A HOOCCOOH: =A6 =A# ? ;E= 7( CHCOOH: =A6 7nA HOOCCH2COOH: =A6 =nA CHSCH2jkCHICHCH2jkCOOH: =A6 7A # A5( =A6 7=AKA# 6r=n5( HOOCCH2jlCOOH: =A6 =KAiA CHSCH2jJlCOOH: =A6 i=nA6A CHSCH2jJCOOH: =A6 567=rA o CHl"COOH#2: =A6 i;6=A HOOCCH2j2COOH: =A6 5EAnA HOOCCH2jSCOOH: =A6 gE6=rA HOOCCHICHCOOH: =A6 =7A # A5( =A6 E=rA # 6r=n5( m CHl"COOH#2: =A6 A5i;6=A p CHl"COOH#2: =A6 67r7i;6=A CHSCH2j2COOH: =A6 E6ArA CHSCH2jJ=COOH: =A6 =ErA CHSCH2jlCHICHCH2j2CH2jCOOH: =A6 An7A

COOH

HOOCCH2CCH2COOH: =A6 A6rA# ? ;E= ;=n;( OH

HOOCCHCH2COOH: =A6 =A# ? ;E= 6F(

OH HOOCCHCHCOOH: =A6 6=ErA# ? ;E= n;(

OH OH

*H H^* C? *H>< (Ho po* ()*H ?d( C? ?d(

N; |nb> 8> 8AWn 6 ?c i;= COOH 6n; =A6 gA# H b; 6F; b;A COOH(:HsCOOH CHzsCOOH C^HwsCOOH : 1= N; ngE>{n 6 8X q 8AWn @n ;6 8AWn 6 b;A n; COOH 6n; =A6 6ng:sCH^sCOOH CsCH^sCOOH CHzsCOOH : 1=

o Gkn Jng n;AcE H= =A6 Jng n;: C Br I : 1=

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CnH^nO^: 4567 n 89n ;

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o |A6 i=n=6A: CMwHzMCOOH # sAno Cch 2ATrA [ 6{n =A6 sA 6;=> > [ gA7r

fK:

* #CMHzwCOO(zCzHw: 6rA567=rAn # 6rA567=r> gA7r( # gA7r( # gA7r( # ? H@C pC (R^*Aa) ?@ AB ?AD:

* CH : 6;p> i;qn ;6 6rng 6 =A6 ;o bAc 8cE 6;E 8e GA7r # CzHw#OH(z* MCOOCH^

COOCH [ zH^O + \QH CzHw#OH(z[ MCOOH [ COOH[ zCOOH

zCOOCH^M z M M M M

* MCOOCH^

COOCH [ zN=OH \ CzHw#OH(z[MCOON= [ COON=[ zCOON=

zCOOCH^M z M M M M

i6 6ng DEF6: mchKt bw m"*aOH4H2O#I mg'ix6' m"m89i4 axit bw##) ?@ *EA ,F:

;6 #CmC( O i7rA6 O =nK7;A6[ 76n[=A6 =>A*** !E : ;6 ; 6 r= CO^?J H^O

") ?@ " H2:;6 ng [ H^

\QN. ;6 rkn

*** !E : M b 6rng ; C 5a Xng ^H # 6

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;6 ng 5a Xng 6 n;6 zH^6r {nl# |v* (O}* C? CH+( e~OA

ch s9 axit: J 5d g 1OH KVng 8 6rEng ;x= =A6 6 K 6rng Mg ;6

#/*"Aa

%OH

#/*"Aa

aE.*.%OH?-

a,

)

2,

,2,.

_

z

_

__ M\wv

(#

(#==

ch s9 xV BhWng ha: J 5d g 1OH 8 6rEng ;x= =A6 6 K ?J J

i;xng ;L6 eng 6rAgA7rA6 6rng Mg ;6 #/*"Aa*.%OH?-!*-aE.*.%OH?-E?A ,,. _______ +=

ch s9 it: 5d g I^ 6; Xng ?J b XA # b 8A b =( 6rng ;C p= M\\g ;6

#/*"Aa

I

I,

2,.

_

(#M\\^

^=

f@A M b 6rng ; C Xng 8e ^I #6s(z(

ch s9 st cQa chKt bw: J 5d g 1OH KVng 8 J i;xng ;= ;Leng 6rAgA7rA6 6rng Mg ;6

xV BhWng ha m"g# chKt bw "t6ng chKt bw '8n tn ti J'F[ng axit bw t /#

T= : =A6 [ N=OH i [ H^O6rAgA7rA6 [ zN=OH i [ gA7r

,!BT b;dA eng: mchKt bw m*aOHI mxB mg'ix6' mH2O

(O}* LH^* LH}L (* d< Hd .^*A

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X PHNG V CHT GIT RA TNG HP

V BhWng

ChKt giDt 6a tng h[B

i9ngnha8

CVng bAE E 6r 8EA KJA b;ng i;qn = K~E bL6 ;ei ?@A 8~E i;qn = n@

,EA KJA b;ng i;qn = K~E ,~E i;qn = n@

CMHzw COON=[

N=6rA 567=r=6 CMHzwCOON= #6rng J i;xng(CM^H^w OSOzN=[

N=6rA =Er> 5En=6 CM^H^wOSOzN= #6rng ;6 gAo6 r=(

hc

nha8

s ,EA J gd ;A8r=np= =A6 8~E J =nAn=>=6

s 1;A goi C=^[

g^[

6rngn@ =6 5En=6

s N=6rA =Er> 5En=6 b;ng ;AWn 6eng 8 n{n E 8A J KVng 8e ?@A n@ A ;A8r ;= =A66;E 8e =n ; =n i;n 5En=6

(hVnhBh7nchnh

s CF EdA n=6rA #;o b=A(p= =A6 6;ng J n=6rA567=r=6 #CMHzwCOON=( n=6rA

i=nA6=6 #CMwHzMCOON=(n=6rA 7=6 #CMHzzCOON=(s CF i;h gA= 6;ng J ;6JE ;6 6;9

sNgJA ;6 gAo6 r= 6ng ;ei ;6 6;9 ;6 JExn 6; ;6 6> 6rkng n; n=6rA;AirA6N=6rA ;AirA6 ;A ; K= b;A gAo6

ng 6=>

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****************************************

CHNG 3: CACBOHIDRATd$ (* u}(A C(C(A Cn"H2O#m n5==rA6: J n;ng =;AKr=6 89n gAn n;6 b;ng 6; 6;p> i;qn 8e n=

fK: gE rE6 ,A5==rA6: J n;ng =;AKr=6 J b;A 6;p> i;qn 5An; r= ^ n5==rA6fK: 5==r =n6 PA5==rA6: J n;ng =;AKr=6 i; i;qn 5An; r= n;AcE

n5==rA6fK: 7nE 6An; X6

dd$ .uCOOA CHJ2O" MyvC #Kng (?J Mw\C #Kng ( K 6=n 6rng n@ C ? ng6 6rng ;~E ;L6 F X i;n p= q> #F ;= r( 8o

AW6 J DE ;n #xn gA J 8ng n;( Trng FE ngA X6 eng n; gE9 ;~E n; b;ng 8A

#b;ng \M ( CTCT:

Kng ; ;: wOH n; n;=E ?J M CHmO 8~E ;

fAL6 gn: CH^OHCHOHysCHO T; 6L gE 6tn 6A ;p >LE ^ Kng mch 5Wng cnh: sgE ?J sgE

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gE9 # zv ( Kng ; ; #\\\z ( gE9 # vy (

Tnh cht ha hc:

a) OE Aa +-"*JK:

TF Khng ?@A CE#OH(^ 8b6 6 KK =n; =:

2CHJ2O C8"OH# "CHJJO#2C8 2H2O

TF Khng ?@A =n;AKrA6 =76A #CHzCO(^O 6: iArAKAn 7567 w gd =76=CvHO#OCOCHz(w

CHkO"OH# "CHSCO#2O CHkO"OOCCHS# CHSCOOH TF Khng ?@A KK |gNOzNHz bL6 6p= |g # gE: ;6 b; ;6

;(

CH2OHCHOHjlCHO 2?g"*HS#2jOH CH2OHCHOHjlCOO*Hl 2?g S*HS H2O

"amni g'8cnat# M gE ^ |g

TF Khng ?@A CE#OH(^OHs 6\ bL6 6p= 8 g; CE^O # gE: ;6 b;;6 ;(

CH2OHCHOHjlCHO 2C8"OH#2 *aOH CH2OHCHOHjlCOO*a C82O 2H2O

"nat6i g'8cnat# "N gch# M gE M CE^O 6 JE KK Br

CH2OHCHOHjlCHO e62 H2O CH2OHCHOHjlCOOH 2He6 TF Khng ?@A HNOzH^SOy 7567

#) %A +-"*JK: TF Khng ?@A H^ # 6 NA 6\( SA6 #

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CH2OHCHOHjlCHO H2 CH2OHCHOHjlCH2OH"sbit'#

") ?@ +M ,/ +-"*J*: !{n 7n reE: M gE ^=n 76>A [ ^CO^

!{n 7n =6A: M gE ^=A6 =6A #A p* LH* C? .uCOOA RuC(OO

C(C(: CH^OHsCHOHzsCOsCH^OH

$%n! m%ch v&n!:

s Ttn 6A Kng ; ?xng w n; ?J v n;

s ng ; ?xng w n; ^ Kng J rE69 ?J rE69

[ Trng KEng K; rE69 6tn 6A ;p >LE Kng ?xng w n;

[ 6rng 6;FA 6An; 6; rE69 Kng ?xng w n; rE69 rE69

(nh chKt 5t ' 5V t6ng thi t nhin

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s !J ;6 rkn bL6 6An; K 6=n 6rng n@ ? ng6 gi rA 8ng = ?J gi ^w ~n gE9

s f ng6 p= 6 ng ;p >LE K rE69 #;AL 6@A y\ (

(nh chKt ha hc: 69ng 6 gE n;ng Uhng 'Vm mKt mV8 // e624Uhng c Bhn %ng 'n mn ?JUhng c B% CHSOH HC' st

Ch G: 6rng 6 1Ac: UCTOO \QOH G!UCOO

gE9 7n8A rE69

F i< 6 bL6 6p= |g CE^O 8cE > r= 6rng 6 1Ac

ddd$ X?CC?ROOA CJ2H22OJJ"

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.F8 GAb;A 6;p> i;qn 5==r# K ;o ?}= 8p( ; KK 5n i; 5i< 6F Khng ?@A KK |gNOzNHzK 6;` 6;> E6 ;AWn bL6 6p= |g

T= 59 8t ;ei 6;

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T;M: =n6 6;p> i;qn ht# HmM\\(:T= 59 8t: M|NTOO?8 ^G!UCOO y|g

T;^: =n6 6;p> i;qn cWn /F# H M\\(:T= 59 8t: M|NTOO ^G!UCOO y|g

M|NTOOK ^|gf>: M|NTOO v|g

d,$ (d*H e(A "CHJ=O#n" A{n bL6 ?@A Cvp=;EA bA= DE= ngE>{n 6 O ng A{n bL6 J4jg'icit6 ; i;qn n;Fn;( b;ng6=n 6rng n@ ?J F KEng A ;E 9

(nh chKt 5t 'AJ ;6 rkn Kng X6 ? 8n; ;`n; JE 6rkng b;ng 6=n 6rng n@n; Trng n@ nng 6} vwC 6r {n 6 KK b7 # ;t 6An; X6( n;AcE 6rng F A ng dp #b;=A 5kn( DE #6F ;EdA( (nh chKt ha hcA

T;p> i;qn 6An; X6 gE:"CHJ=O#n nCHJ2O 2nCO2 2nC2HOH

P< JE ?@A KK A6 KK JE =n; 6 X (vO (H*H (d*H e( (RO* C+f ?*H " u} (R*H

u?* HL#AnCO2nH2O "CHJ=O#n nO2

S CHUYN H| TINH BT TONG C TH:TAn; X6 a,.+aJaOH Q^ 876rAn a,.+aJaOH Q^ =n6 ,a)aJaOH Q^ gE

CO^[ H^O

GAg7n # 6An; X6 8Xng ?6(# 6rng 6Jn X F DEF 6r`n; b;ng 6 r= 5==r(,$ *.u.OOA "CHJ=O#n"

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?` VA4"C+u (vO LH* (( CK8 t Bhn tAgt n;AcE sgE A{n bL6 ?@A n;=E ng A{n bL6

sMysgAA66 6;Jn; ; b KJA b;ng i;qn n;Fn; b;ng kn

C(C(A CHkO2"OH#Sjn (nh chKt 5t ': J ;6 rkn Kng 5eA 6rkng b;ng A ? b;ng 6=n

6rng n@ ?F F KEng A b;F n;ng T|N 6rng N0"C Sf|Y4 # ;; CE#OH( NHz i;

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b;ng i;n

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Trng F i;qn 6 TAn; X6 7nE: M k6 ; CvHM\Ow ;AcE KJA

!mw \7 Mm \M\M\ 7

****************************************CHNG : AMINd$ |?*H LH}LA

o (n g9cch%c: M WCC# 76 76 iri E6 ( [ Q A, a,[ y'[ amino (n thay th: * *4* [ M HC[ Q A, a,[ amin

f@A: Ns: b ;AWE ; AL6 8 J =An ^

NNs: b ;AWE ; AL6 8 J =An z |An M 6;` b;ng b ;AWE

T{n HCm 6{n n;Fn;[ 6{n CC./ $0:

H[B chKt (n g9c ch%c (n thay th (n thFng

CHzNH^ 76>=An 76=n=AnCHzCH#NH^(CHz A5iri>=An iri=ns^s=An

CHzNHC^Hw 76>76>=An Ns76>76=n=AnCHzCH#CHz(CHNH^ A5E6>=An ^s76>iri=nsMs=AnCHzCHCH#NH^(CHz 57sE6>=An E6=ns^s=An#CHz(zCNH^ 67r6sE6>=An ^s76>iri=ns^s=AnCHzNHCHCHCHz 76>iri>=An Ns76>iri=nsMs=AnCHzNHCH#CHz(^ A5iri>76>=An Ns76>iri=ns^s=AnC^HwNHC^Hw 8A76>=An Ns76>76=n=An#CHz(NC^Hw 76>8A76>=An NNs8A76>76=n=AnCvHwNH^ i;7n>=An 7n7n=An =nAAn

Ch :

s T{n F n; =nb> 8 6;7 6;< 6 ; FA = s f@A F =An ^ ?J z ;n ; KJA n;6 ;{n 6 N 6r@ A n; 6;L p= =An s 1;A n; NH^8ng ?=A 6rx n; 6;L 6;` gJ n; =An f Kh: CHzCH#NH^(COOH #=A6 ^s=Aniri=nA(

o (n thFngA

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|nAAn CvHwNH^# mz(o PHN !OI: ^ F;

T;7 8o 8A E 6 p= gd HC: |An 6;9 |An |An K ?xng

T;7 |An: |An M |An ^ |An z

dd$ ()*H CH+( ,-( .)Ao 76>=An 76>=An KA76>=An 6rA76>=An: ;6 b; VA b;=Ao |nAAn: ;6 ng b;ng JE 8X 6 6=n 6rng n@ 6=n 6rng 76=n 7n7n , qE

6rng b;ng b; =nAAn ;E>n 5=ng JE nqE 87n ?` A ;= A A b;ng b;o NHIT , SI:

|An M^ HC 69ng 7 # K ;6 H[( 6n; = 6ng:

fK: #CHz(zCs #CHz(^CHs C^Hws CHzs # =nb>( 5d C p= =nb> Jng 6ng 6n; = Jng 6ng N; ;6 7 # b; ;6 H[( 6n; = gA:fK: CNs s Cs Brs Is CHzOs CvHws CH^mCHs Trng K> F ;6 6n; = >LE n;:

o NHz: 6n; = 6rEng gA=n 6rng K>o K bAc N=OH 1OH C=#OH(^ B=#OH(^: 6n; = n; n;6o CF =An 6;9 6n; = >LE ;9n NHzo Tn; = n; >LE gA= F =An 6;9 xn K 5 n; ;ng p= F

n; 6;L b;F n;=E 6r{n n;qn 6;9:fK: isCHSCvHyNH^ CH*H2 isO2*CvHyNH^o fK K>: CvHwNH^ NHz CHzNH^ #CHz(^NH N=OH

C4c 567 t8 9nh h;n! (6n l' c?a am+n:

s 6 8X 776rn 6r{n ngE>{n 6 N: 6 8X Jng = =9 Jng n; ?J nge As HAWE

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i;h 6;EX ?J gd ;A8r=n f Kh 6n; =9 p= #CHz(NH CHzNH^ #CHz(zN #C^Hw(NH #C^Hw(zN C^HwNH^d,$ ()*H CH+( H>? H@CA

o Tn; =:

R*H2 HC' R*HSjC'

R*H2 H2XOl R*HSj2XOl M n; NH^s bL6 ;ei MH[ NHz

P;7n>=nArE= CH*HSjC' *aOH CH*H2 *aC' H2O R*H2 H2O R*HSj OH J DE 6 ;= =n;

R*HSj H2O R*H2 HSO

SR*H2 C'S SH2O "OH#S SR*HSC'SCnH2nS* C'S SH2O "OH#S SCnH2nl*C' f@A DE 6 i;7ni;6=7An:

76>=An =nAAnQE 6 =n; sssssssssssss

i;7ni;6=7An Htng sssssssssssss

o P< ?@A HNO^:

|nb>=An M [ HNO^ =n [ N^[ H^OR*H2 H*O2 ROH *2 H2O

|An NH^s C M ^HNO =n M \

QC-O =nK7;A6 |An NH^s C ^ ^HNO =n ^

\QC-O 76n

|An NH^s C z ^HNO =n z

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|An 6;9 M [ HNO^ Aa?\

EdA KA=nACH*H2 H*O2 HC' C

\\ w\ CH*2C' 2H2O

P;7n>KA=nA rE=

o P< =nb> ;= 6;=> 6;L ngE>{n 6 H p= n; NH^:CH*H2 CHSd CH*HCHS Hd

76> AKE= Ns76>=nAAno P< 6;L n;qn 6;9 p= =nAAn:

# =An 6} NHz?J =nb>;=g7nE=:*HS +$I R*H2 +$I "R#2*H +$I "R#S*

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|v* (O}*Ao ,d6 =An:

OH) ^ s ^CO) m^

zn=An =An n 89n ;

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# ; s=An=A6@A 6{n

nJ>(

NH^CH^COOH |A6 =An76=nA |A6=An=76A

G>An G> w

CHzCH#NH^(COOH |A6^s=Aniri=nA

|A6 s=AniriAnA

|=nAn |=

#CHz(^CHCH#NH^(COOH |A6 s=Anszs76>E6=nA |A6

s=AnA5?=7rA f=An f= MM

HOCvHyCH^CH#NH^(COOH |A6 s=Ans z#ys;AKrAi;7n>(

iri=nA

|A6 s=Ans s#is;AKrA

i;7n>(iriAnA

T>r5An T>r M

HOOC#CH^(^CH#NH^(COOH |A6 s=Ani7n6=nKAA

|A6 s=AngE6=rA

|A6gE6=A

GE My

NH^#CH^(yCH#NH^(COOH |A6 vs

KA=An;7=nA

|A6 s

KA=An=irA

!>5An !>5 My

()*H CH+( ,-( .): ;6 rkn b;ng JE ? ;9A ng6 K 6=n 6rng n@

s Trng i;qn 6 =An =A6 n; NH^?J n; COOH 69ng 6F ?@A n;=E 6 An ng f`?> =An =A6 bL6 6An; 6tn 6A Kng An ng s Trng KEng K; Kng An ng ;E>n X6 i;~n n; 6;Jn; Kng i;qn 6

LH* .OvdA^\ =An =A6 8e i;qn 6;Jn; w n;

a) NA, 1: F =An =A6 gd b;ng i;qn b n@ 6;EX n; nJ> v =An =A6: G#G( |= #|( f= #f( !7E #!( I!7 #I( Pr #P(

#) NA, 2: F =An =A6 gd J n;qn 6;9 6;EX n; nJ> z =An =A6: P;7 #( T>r#Y( Tri #(

") NA, =: F =An =A6 gd =9 6; 8AWn K9ng 6;EX n; nJ> z =An =A6: !>5#1( |rg #( HA5 #H(

!) NA, :F =An =A6 gd i;qn b;ng 6; 8AWn 6;EX n; nJ> v =An =A6:S7r #S( T;r #T( C>5 #C( 76 #( |5n #N( Gn #Q(

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/) NA, Z: F =An =A6 gd =A6 6; 8AWn q 6;EX n; nJ> ^ =An =A6: |5i #(GE #4(

()*H CH+( H>? H@C: (nh baaxit: "H2*#xR"COOH#yo m> iHmo > iH

o > iH (nh 'Fng tnhAo TF Khng ?@A =A6 n; 6 EdA =nA# i< > r= n; NH^n; =An(

H2*CH2COOH HC' C'HS*CH2COOH;o: HS*CH2COO HC' C'HS*CH2COOH

o TF Khng ?@A = n; 6 EdA ?J n@# i< > r= n; COOH n; =A6=>A(

H2*CH2COOH *aOH H2*CH2COO*a H2O;o: HS*CH2COO *aOH H2*CH2COO*a H2O

L% st ha# i< > r= n; COOH n; =A6 =>A(

L% 5Mi H*O2# i< > r= n; NH^n; =An(H2*CH2COOH H*O2 HOCH2COOH *2 H2O

axit hiN6xiaxtic L% t6ng ngFng:

nH*HRCOOH \ "*HRCO#n nH2O

Ch :o CF =An=A6 6;A{n n;A{n 8cE J F s=An=A6o EdA nN=6rA p= =A6 gE6=A J 6;Jn; i;~n p= X6 ng6o |A6 gE6=A: 6;Ed ; 6re 6;~n bAn;o 76;AnAn: 6;Ed g=n "CHSXCH2CH2CH"*H2#COOH#

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o |A6 vs=An;7=nA ?J =A6 s=An;7i6=nA J ngE>{n AWE 5n E6 nAnsvnAns

CH^sCH^sCmO

o nCH^ \ s#sHNsCH^wsCOs(sn

CH^sCH^sNH

C=ir=6= T9 =irn #;=> iA=ir=A6(# ?` A{n bL6 sCOsNHs 6rng ?xng b cn ?@A 6\(o ; F A 69 6r{n 6;p> i;qn:

8~E 6A{n: 69 nJ> 5a 6F Khng ?@A nH^O 8 6 n{n =An=A6 6rng KK N=OH nng K: =An=A6 6F Khng ?@A N=OH n; COOH 6rng KK HC K: =An=A6 6F Khng ?@A HC n; NH^

o ^ ;6 C2HOS*2[N=OH ;; ^ b; J DE 6 ;= =n; C2H*HS*O2 *aOH C2H*H2 *a*OS H2O

CHS*H2"*OS#CHS*aOH "CHS#2*H *a*OS H2Oo *H2RCOOH HC' *HSC'RCOOH

*HSC'RCOOH 2*aOH *H2RCOO*a *aC' H2O*H2RCOO*a 2HC' C'HS*RCOOH *aC'

o |An=A6 MCOOH MNH^: CnH^n[MON

o nHC'I"mm89imaminaxit#S4n*aOHI"mm89imaminaxit#22nOHI"mm89imaminaxit#S

o Cng th%c Bhn t CAH5O2N c c4c ()n! phBn c7 t%o m%ch h; thn!!Dp:

s |An =A6 HNCOOHs 4567 p= =An =A6 HNCOOs EdA =nA p= =A6 =nb=nA COONHy?J COOHzNs Hei ;6 nA6r NO^

o

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CHNG E: PEPTIT PROTEIN ngEtn gd 6} F s=An=A6 6{n i7i6A6: 6;7 6;< 6 6} 8~E N 8Ln 8~E C b;ng 8 nge

o F; M:M `" aE+ "Ba "4" a,*aE #b cd- e cd- Nf] #g Ah- ` Aa

#i Ah- ` +) f M "Ba aE cd- C c^j" k -M)!:7+a5lG>y'|=ny'!>5y's|=s!>5sf= C+u (vOA n;AcE 89n ? i7i6A6 A{n bL6 A ?@A n;=E 6 6;Jn; ir67An ng F A{n bL6

i7i6A6 sCONHs LH* .OvdA

o ^ A i7i6A6: OAgi7i6A6: sM\ gd s=An=A6 ?J 8e gA 69ng

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o P< JE BAEr7: i7i6A6 # ^ A{n bL6 CONH 6r {n( Pr67An 6F Khng ?@A KK CE#OH(^6 i;

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CHNG F: POLIMEd H}d *d

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S$ |anh BhB

s PA [ 6{n p= nn7 #nLE 6{n n7 gt ^ 6} 6r {n ;o 6} ;=A n7 6 n{n iA7 6;6{n p= n7 i;A 8 6rng ngo 89n(

s X6 5d iA7 6{n rA{ng #6{n 6;ng 6;ng( f Kh:

dd C+u (RCJ$ Cc /ng cK8 t6c mch B'im

=( ; b;ng i;qn n;Fn; f Kh: iA76A7n =A9( ; i;qn n;Fn; f Kh: =Ai76An gAg7n( ; ng @A f Kh: = 5E E ;= n;= =b7A6

2$ CK8 t Ni8 hWa 5V Uhng Ni8 hWa

a) Cm- o* cp- Aqa: F k6 ; ndA n;=E 6;7 X6 6r6 6 n;6 8n; #;ung ;=n 6;7 bAE 8~E nd8EA( f Kh:

#) Cm- o* VAr cp- Aqa: F k6 ; ndA ?@A n;=E b;ng 6;7 6r6 6 n;6 8n; #;ung ;n 6;7bAE 8~E ndA 8~E ; 6;` 8~E ndA ?@A 8EA( f Kh:

ddd ()*H CH+( ,-( .)

H~E ;L6 iA7 J ;6 rkn b;ng => ;9A b;ng n;AW6 8X nng ;> F 8n;

,= 5d b;ng 6=n 6rng F KEng A 6;ng 6;ng X6 5d 6=n 6rng F KEng A ;E 9 6;; ;e6 6;Jn; KK n;@6 ? Kh: = 5E 6=n 6rng B7n7n TE7n

PA7 J b;A nng ;> 6 6;Jn; ;6 ng 8 ngEXA 5a rkn A 8 J CHT NHIT O

PA7 J b;A nng ;> 6;` i;qn ;p> 8 J CHT NHIT N

PA7 :

Tn; K: P4 PP # chKt /( Tn; 8Jn ;tA: Ca s8

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Tn; b 6;Jn; 5eA K=A cn: nAn # t1 (

Trng 5Ed6 b;ng gAxn: P

Tn; F; 8AWn F; n;AW6: P4 PfC

Tn; Fn Kn: iA=76A7n iA6;Ai;7n

d, ()*H CH+( H>? H@C

J$ Lhn %ng giT ng8yn mch B'im

EEEE B% thQy BhnA

a ol+Iv+n5l aAJtat I.K t4c "#n! vL+ "7n! "Mch NaOH:

EEEE B% c{ng N9i 5Mi cc B'im cWn 'in Ut b{iA= Cao 7 th+n nh+n t4c "#n! vL+ HCl:

C= 5E ;A8r ;=

c ol+Iv+n5l cloP7a I.C t4c "#n! vL+ Cl2A#gA 5 < ^ k6 ; 6;L M ngE>{n 6 (

T9 rAn

2$ Lhn %ng Bhn czt mch B'imA tinh b{t4 xn'8'4 B6tin N1n gin4 ni'n4 LX4 ca s8thin nhin4;

a h9n Qn! th?5 phBn pol+JtJA

= h9n Qn! th?5 phBn pol+pJpt+t hoDc pol+am+t:

NAn vc h9n Qn! th?5 phBn t+nh =tS AJnl7lo>'

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J$ Lhn %ng t6ng h[B

a Wh4+ n+m:s TrVng ;ei J DEF 6r`n; bL6 ;ei n;AcE i;qn 6 n; #n7( gAdng n;=E ;=> 69ng 6 n;=E 6;Jni;qn 6 r6 @n #iA7(s ,AcE bAWn ~n ?c E 6 p= n7 6;= gA= i;n

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=A6 s=An7n=n6A NAn #69 7n=n(

,d

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Clo ha nh

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gA=ns 1;ng nng ;> b;ng 6=n 6rng n;AcE KEng A ;E 9 KVng 5n E6 8t 8AWn ? F>

2 * T

EEE

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" caB6'actam#

NjkON -F: X[ n

= T' pol+JtJ Ic nh+7 nhm JtJ:

T' kKUKN: X[1q2n I t' $KCRON:

Qn! "#n!: "t v9+ ma5 mDcSc T' v+n5l+c Ic nh+7 nhm pol+v+n5l:

T' .jNrkONI T' .jNrkjC: X[ n

T' NjTRON I T' OkON: X[ @3n

Qn! "#n!: "t v9+ ma5 s7n 4o mS =n u+ lJnS (an o PtS

" C4c lo%+ t' Vh4c:

T' KibTKT: hwn hup AJnl7lo>o tP+aAJtat v AJnl7lo>o "+aAJtat g hwn hup KAJton vbtanol t' KibTKT I @@-F\\C

T' .jUCO: hwn hup AJnl7lo>oS CU2v NaOH "" nhLt .+co +:OH y^ t' .+co

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S C?O XuA C ;=A A = 5E: = 5E 6;A{n n;A{n ?J = 5E 6ng ;ei

a Cao 7 th+n nh+n: X[En

&&& Cm- n":

s Cng 6; 6} p q> = 5E 8Jn ;tA 6d6 #n; E 6r A5 8AcE ;x=( b;ng Kn n;AW6?J 8AWn b;ng 6; b; ?J n@ b;ng 6=n 6rng n@ 76=nn;ng 6=n 6rng ng ?J 7n7ns C= 5E 6;A{n n;A{n ; i;n

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Cao 7 +opPJnAX[Ens TrVng ;ei A5ir7n ;W 6F 8o AW6 6= 8e iAA5ir7n gA J = 5E A5ir7n E ;`n; A5;AL y g~n gAdng = 5E 6;A{n n;A{n

s NgJA r= ngA 6= xn 5n E6 iArir7n ?J iArir7n CF iA7 nJ> 8cE 8o 6n;

8Jn ;tA n{n 8e gA J = 5E rir7n ?J = 5E rir7n C;ng cn ?@A K~E ;9n = 5EA5ir7n

X[S@n X[ n

OkjUTjRbN I U: X[1\n

OkjROjkbN I : X[2n

l O |}*A

/n 86 3manNhit: X[ n

PA#Er7 =n87;A6(

Qn! "#n!: "4n vt =xn! !wS cht "yoS

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