Hirschprung disease

2
HIRSCHPRUNG DISEASE Congenital Megacolon

Transcript of Hirschprung disease

Page 1: Hirschprung disease

HIRSCHPRUNG DISEASECongenital Megacolon

Page 2: Hirschprung disease

Failure of NCC to migrate to a certain portion of colon or rectum---Absence of Parasympathetic.NS there---non innervated musculature---Small diameter of affected region---Portion proximal to it is Dilated

Caused by gene mutations