PLACENTAL HORMONES HCG AND HPL

@copyright and owner POKHREL,BHARAT

DOCTOR OF MEDICINE

PLACENTA

l FOETAL ORIGIN → CHORION FRONDOSUM l MATERNAL ORIGIN → DECIDUA BASALIS

HORMONES

PROTEIN HORMONES STEROID HORMONES

l hCG l hPL l hCT l Hypothalamic and

pituitary like hormones l Others like inhibin, relaxin

and beta endorphins

l Esrogens l Progestin

HCG (Human chorionic gonadotropin)

HPL (Human placental lactogen)

1)It is a hormone produced by the syncytiotrophoblast, a portion of the placenta following implantation

2)The pituitary analog of hCG, known as luteinizing hormone

3)promotes the maintenance of the corpus luteum during the beginning of pregnancy

4) hCG can also be used clinically to induce ovulation in the ovaries as well as testosterone production in the testes.

1)Also called human chorionic somatomammotropin (HCS), is a polypeptide placental hormone.

2)Its structure and function is similar to that of human growth hormone

3)↓ maternal insulin sensitivity leading to an increase in maternal blood glucose levels.

4)↓ maternal glucose utilization, which helps ensure adequate fetal nutrition (the mother responds by increasing beta cells). Chronic hypoglycemia leads to a rise in hPL.

Picture taken from : http://www.slideshare.net/NadaGYoussef/lecture-4-development-inheritance

PRODUCTION OF HCG