HANLI LIU - University of Texas at Arlington · Web viewSept. 15, 2011invited for an invited...

Updated in June, 2012

Curriculum Vita

HANLI LIU (Female), Ph.D.

Biomedical Engineering Program Office: (817) 272-2054The University of Texas at Arlington Secretary: (817) 272-2249Box 19138 FAX: (817) 272-2251Arlington, Texas 76019-0138 e-mail: [email protected]

1. EDUCATION AND POST-DOCTORAL TRAINING:

University Degree Major Dates

University of PennsylvaniaPhiladelphia, PA

Post-doctoralFellow

Biomedical Optics and Instrumentation

June 1994 - Aug. 1996

Wake Forest UniversityWinston-Salem, NC Ph.D. Applied Physics May 1994

Wake Forest UniversityWinston-Salem, NC M.S. Applied Physics May 1990

Beijing Normal UniversityBeijing, P. R. China B.S. Physics July 1983

2. PROFESSIONAL EXPERIENCE:Sept. 2006 – present Professor of Bioengineering, Bioengineering Department,

The University of Texas at Arlington, Arlington, TX.Sept. 2001 – Aug. 2006 Associate Professor, Biomedical Engineering Program,

The University of Texas at Arlington, Arlington, TX.Sept. 2000 – present Affiliate Member of the Institute for Cancer Research, The

University of North Texas Health Science Center, Fort Worth, TX.Sept. 1996 – present Adjunct Faculty, Joint Program in Biomedical Engineering,

The Univ. of Texas Southwestern Graduate School of Biomedical Sciences, Dallas, TX.

Sept. 1996 – Aug. 2001 Assistant Professor, Biomedical Engineering Program, The University of Texas at Arlington, Arlington, TX.

June 1997-Aug.1997 Summer Research Faculty Fellow, Air Force Research lab., Albuquerque, NM

June 1994-Aug.1996 Post-doctoral Fellow, Britton Chance’s Laboratory,Dept. of Biochem. And Biophys., The Univ. of Pennsylvania, Philadelphia, PAResearch Scientist, NIM Incorporated, Philadelphia, PA.

June 1992-Aug.1996 Research Associate, University City Science Center, Institute for Biophysical and Biomedical Research (IBBR), Philadelphia.

Sept.1989-May 1992 Research assistant, Physics Dept. Wake Forest University, NCSept 1987-Aug. 1989 Teaching/Research assistant, Physics Dept. Wake Forest Univ.,NC

Hanli Liu, BME1

mailto:[email protected]


3. HONORS: Recipient for the following awards:

Sept. 15, 2011 invited for an invited presentation on the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside. September 15-16, 2011, NIH, Bethesda, Maryland. The title of the presentation was “Translation of fNIRS for clinical applications: objective assessment for pain perception and neuropsychological tests.”

February 2008 College of Engineering Excellence in Research Award (one person per year in the college), University of Texas at Arlington

April 2005- April 2009 Annual Research Excellence Award, University of Texas at Arlington

(cash award).October 2007 being selected to be an Associate Editor for Optics Express, which is a fast

growing peer-reviewed, International Optics Journal, with an impact factor of 3.8 in 2006.

May 19 2007 distinguished speaker to deliver the hooding address in Wait Chapel during the hooding ceremony held by the Graduate School of Wake Forest University.

Jan.-May, 2006 Recipient, Faculty Development Award from UT Arlington for Sabbatical in Functional Neuro-imaging.

Jan. 2005 Recipient, the STARS program from the University of Texas System to receive $500,000 for equipment fund.

Jan. 6-7, 2005 Invited to attend “The Academy of Medicine, Engineering, and Science of Texas,” Omni Mandalay Hotel at Las Colinas, Texas.

(two faculty members per university within the UT system were invited.) 2004-present, Listed in Marquis Who's Who in the World, 2005 Edition.April 2004 University Outstanding Research Achievement Award, UTA.2003-present, approved membership for International WHO’S WHO of Professionals2003-present, Listed in Marquis Who’s Who of American Women.2002-present, Listed in Marquis Who's Who in America.October 1999 "Chun-Hui" Travel Fund Award for Outstanding Abroad Chinese

Scholars, sponsored by Education Ministry of China.February 1999 College of Engineering Outstanding Young Faculty Award, UT

Arlington;April 1998 Outstanding Young Scientist Award, Houston Biomedical

Engineering Symposium, Houston, TX.May 1990 Sigma Xi Research Award, Wake Forest Chapter, Winston-Salem, NC. May 1990 Graduate Student Association Award for best M. S. thesis, Wake Forest U.

Nominated for the following awards at the level of the University and the State of Texas:

February 2009 Nominee for 2008-2009 University Award for Distinguished Record of Research, from College of Engineering to UT Arlington.

May 2006-2008 Nominee for Edith and Peter O'Donnell Awards in Engineering, from UT Arlington to The Academy of Medicine, Engineering and Science of Texas.

Dec. 2006 Nomination for Membership to the Academy of Distinguished Scholars,

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from College of Engineering to UT Arlington.

4. MEMBERSHIPS IN PROFESSIONAL SOCIETIESSPIE, international optical engineering society (since 1992 to now); APS, American Physical Society (since 1989 to now);OSA, Optical Society of America (since 2004 to now);IEEE-LEOS, IEEE Laser and Electro-Optical Society (2004-2006);IEEE Women in Engineering (2004-2006).

5. REVIEWER FOR PEER-REVIEWED JOURNALS AND THE NIH GRANTS: Associate Editor: Optics Express (Oct. 2007-Oct. 2010);Journal of Optical Society of America A: Optics and Image Science;Applied Optics; Applied Spectroscopy;Optics Letters; Journal of Biomedical Optics; Optical Engineering; Shock Waves;Optics Express; NeuroImage;Physics in Medicine and Biology; Medical Physics;Photochemistry and Photobiology; Journal of Neural Engineering;Review of Scientific Instruments; Biomedical Engineering Online.

Committee member for OSA Technical Program Committees (2000-2004).

NIH ad hoc study-section panel member for the NIH grant proposal reviews.(1) Special emphasis panel: ZRG1 SBIB-V 50 R; Bioengineering Research

Partnerships; June 17, 2009.(2) Special emphasis panel: ZRG1 SBIB-U 53 R; RFA-OD-09-008 BRDG-SPAN

and RFA-OD-09-009 Catalyst ARRA Review panel 15; Nov. 5, 2009.(3) Special emphasis panel: ZRG1 SBIB-U50; Academic Industrial Partnerships ;

Bahia Hotel, San Diego Feb. 13, 2010.(4) Special emphasis panel: ZRG1 SBIB-J (80) S; Development Methods of In

Vivo Imaging and Bioengineering Research; Oct. 18-19, 2010.(5) 2011/05 ZRG1 DTCS-A (81) S; Cancer and Musculoskeletal Imaging

Applications; Feb. 18, 2011 (mail reviewer)(6) 2011/05 ZRR1 BT-7 (01) 1; Biotechnology 2011; Feb. 23-24, 2011.(7) 2011/10 ZRG1 DTCS-U (81) S; Clinical and Translational Imaging

Applications; June 13, 2011 (mail reviewer)(8) 2012/01 ZRG1 OTC-X (90) A: Cancer Therapeutics; Internet Assisted

Meeting (IAM), September 27-28, 2011. (9) 2012/01 ZRG1 CB-C (02) M: Cell Biology; Internet Assisted Meeting (IAM),

Dec. 8-9, 2011

6. FUNDED OR COMPLETED RESEARCH GRANTS:

Currently funded grants:

1) “Near Infrared Brain Imaging for Building Treatment in Children with Cerebral Palsy”Co-PI: Hanli Liu (PI: George Alexandrakis) Agency and type: NIBIB/NIH (R01);

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Period: 04/01/2011-03/31/2014. Total Amount: ~$1,180,000.

2) “Feasibility of Prostate Cancer Diagnosis by Transrectal Photoacoustic Imaging”PI: Hanli Liu (Concept Award) Agency and type: Department of Defense Prostate Cancer Research Program; Period: 02/01/2011-01/31/2012. Total Amount: $112,000.

3) “Transrectal Imaging of Prostate Cancer Using a Globally Convergent Method”PI: Hanli Liu, Ph.DAgency and Type: NCI/NIH (R01) Period: 07/01/2010-08/31/2013. Total Amount: $958,666.

4) “A Breakthrough Probe Technology for Translating Near-Infrared Brain Imaging into a Routine Clinical Tool for Assessing Motor Deficits in Children with Cerebral Palsy” co-PI: Hanli Liu, Ph.DAgency and Type: UT Arlington/UT Dallas/ Texas Instruments Medical Technology

Research Program Period: 01/15/2010-01/14/2011. Total Amount: $100,000.

5) “Computational Optical Tomography for Anti-stroke Therapy,”PI: Hanli Liu in collaboration with UNTHSC from Fort Worth.Agency and type: NINDS/NIH (R33) Period: 06/2009-05/2012. Total Amount: ~1,370,646.

6) Equipment fund for purchasing a “High-density NIRS brain imaging system”PI: Hanli Liu, Ph.DAgency and type: College of Engineering, UT ArlingtonPeriod: 04/01/2009-08/31/2009Total Amount: $38,000

7) “Development of a Real-Time, Optically Guided Needle Biopsy System for Improved Prostate Cancer Diagnosis”PI: Hanli Liu, Ph.DAgency and Type: Texas Ignition Fund from the University of Texas System

Board of RegentsPeriod: 10/01/2009-01/30/2011. Total Amount: $50,000.

8) “Development of a Hybrid Optical Biopsy Probe to Improve Prostate Cancer Diagnosis,”PI: Hanli Liu (Idea Award); in collaboration with UTSW from Dallas

and UNTHSC from Fort Worth.Agency and type: Department of Defense Prostate Cancer Research Program; Period: 04/01/2009-03/31/2012.

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Total Amount: $518,327.

9) “Computational Optical Tomography for Anti-stroke Therapy,”PI: Hanli Liu in collaboration with UNTHSC from Fort Worth.Agency and type: NINDS/NIH (R21) Period: 06/2007-05/2009. Total Amount: $368,944 (with supplement of $99,999).

10) “Assessment of Neuroplasticity in children with CP: A multi-source-detector near infrared spectroscopy imaging study,”PI: Mauricio Delgado, M.D., UTSW from Dallas and Texas

Scottish Rite Hospital for Children Co-PI: Hanli Liu, Ph.D. Agency: United Cerebral Palsy Research & Educational FoundationPeriod: 01/2008 – 12/2009.Total Amount: $100,000

11) Establishment of a Comprehensive Medical Imaging Center, in joint collaboration with UT Southwestern Medical Center at Dallas and The University of Texas at Dallas.

PI: Khosrow Behbehani; Co-PI (NIR imaging): Hanli Liu, Ph.D. Agency and type: Congressional “Ear Mark” funding Period: 2006 – 2009.

Total Amount: $2,400,000 (UTA portion).

12) Establishment of a Comprehensive Medical Imaging Center, in joint collaboration with UT Southwestern Medical Center at Dallas and The University of Texas at Dallas.

PI: Khosrow Behbehani; Co-PI (NIR imaging): Hanli Liu, Ph.D.

Agency and type: Congressional “Ear Mark” funding Period: 2006 – 2009. Total Amount: $579,000.

Completed grants:13) “Novel Approach to Measurement of Hot Flashes by Near Infrared Spectroscopy”

PI at UTA: Hanli LiuSource and type: UTA/UNTHSC research seed funding for collaboration. Period: 01/06-12/06. Total Amount: $15,000

14) “Microcirculatory Dysfunction: Potential Therapeutic Target of Estrogen Against Ischemic Stroke”PI at UTA: Hanli LiuSource and type: UTA/UNTHSC research seed funding for collaboration.Period: 01/06-12/06. Total Amount: $12,500

15) “Inter-disciplinary Laboratory for Diffuse Optical Medical Imaging”PI: Hanli Liu, Ph.D.

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Agency and type: The University of Texas System, STARS program for funding equipment. (It is faculty recruitment and faculty retention fund.)

Period: 02/01/05 – 02/28/06. Total Amount: $500,000.

16) “Noninvasive Monitoring for Optimization of Therapeutic Drug Delivery by Biodegradable Fiber to Prostate Tumor”PI: Dan Popa (New Investigator Award); Co-PI and mentor: Hanli Liu, Ph.D.Agency and type: Department of Defense Prostate Cancer Research Program; Period: 04/04-03/07. Total Amount: $326,756.

17) “Simultaneous Monitoring of Vascular Oxygenation and Tissue Oxygen Tension of Breast Tumors under Hyperbaric Oxygen Exposure”PI: Mengna Xia (BME Ph.D candidate); Mentor: Hanli Liu, Ph.D.Agency and type: Department of Defense Breast Cancer Research Program; Pre-

doctoral Traineeship AwardsPeriod: 04/04-03/08. Total Amount: $90,000.

18) “Hemodynamic Imaging for Brain Tumor Prognosis”PI: Hanli Liu, in collaboration with UTSW at Dallas;Agency and type: NCI/NIH (R21/R33)Period: 07/01/03 – 06/30/ 08. Total proved amount: $1,036,516.

19) “Monitoring of Breast Tumor Response to Local Chemotherapeutic Agent Delivered by Biodegradable Fibers,”

PI: Jae G. Kim (BME Ph.D candidate); Mentor: Hanli Liu, Ph.D.Agency and type: Department of Defense Breast Cancer Research Program; Pre-

doctoral Traineeship AwardsPeriod: 06/03-05/07. Total Amount: $90,000.

20) “Assessing Vascular Oxygen Dynamics for Breast Tumor Prognosis: comparison between MR BOLD and Near Infra-Red method”

PI: Yueqing Gu (post-doctoral fellow); Mentor: Hanli LiuSource and type: Department of Defense Breast Cancer Research Program; Period: 09/01-08/04. Total Amount: $150,000.

21) "Non-Invasive Monitoring of Breast Tumor Oxygenation: A Key to Tumor Therapy Planning and Tumor Prognosis"PI: Hanli Liu, Ph.D.

Hanli Liu, BME6


Agency and type: Department of Defense Breast Cancer Research Program.Period: 9/1/00 – 8/31/04. Total Amount: $298,104.

22) "A Near-Infrared Probe for Localization in DBS (Deep Brain Stimulation)" PI: Cole Giller, M.D., Ph.D (UTSW); Co-PI: Hanli Liu, Ph.D.Agency and type: NIH, RO-1Period: 10/00-8/31/04. Total Amount: $654,330.

23) “Development of a brain spectrometer for guiding brain surgery and in-vivo monitoring of cerebral oxygenation”PI: Hanli Liu, Ph.D.Agency and Type: the Whitaker Foundation.Period: 9/1/97-2/28/01. Total Amount: $197,301.

24) “In vivo Recording from GFP-labeled Neurons in Freely-behaving Normal and Mutant Mice”PI: Rolf Joho, Ph.D. (UTSW); Co-PI: Hanli Liu, Ph.D.Agency and Type: Haberecht Wildhare-Idea Research Grant, UTSW.Period: 10/1/99-10/1/01. Total Amount: $25,000.

25) “An Automated Neuro-Probe for Localization in Deep Brain Stimulation”PI: Hanli Liu, Ph.D.Agency and Type: ARRI Research Enhancement Program Grant, UTAPeriod: 9/1/99-8/31/01. Total Amount: $15,000.

26) “A Continuous-Wave Approach to 3-D Imaging through Turbid Media with a Single Planar Measurement”PI: Hanli Liu, Ph.D. Agency and Type: AFOSR, Summer Extension GrantPeriod: 6/1/98-5/31/99. Total Amount: $25,000.

27) UTA Research Enhancement Program, 1/1997-8/1997, $10,000.

28) “Electro-Optical Scanner for Detection of Brain Inhomogeneities,” PI: Hanli Liu, Ph.D. Agency and Type: NIH, SBIR Phase I grant;Period: 7/1/94-12/31/94. Total Amount: $50,000.

29) “Electro-Optical Scanner for Detection of Brain Inhomogeneities,” PI: Hanli Liu, Ph.D.

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Agency and Type: NIH, SBIR Phase II grant;Period: 10/1/95-9/30/97. Total Amount: $500,000.

7. U.S. PATENTS1) Inventors: Hanli Liu, Vikrant Sharma, and Claus G. Roehrborn;

Title: “Apparatus and Methods for Guidance of Prostate Needle Biopsy,”Patent: U.S. patent pending, filed from UT Arlington in July, 2011.

2) Inventors: Hanli Liu, Edward Livingston, and Boping Wang;Title: “Porcine Biliary Tract Imaging,” Patent: U.S. patent pending, filed from UT Arlington on May 21, 2008.

3) Inventors: Hanli Liu, Disha Peswani, and Jeffrey Cadeddu;Title: “Optical Methods to Intraoperatively Detect Positive Prostate and Kidney

Cancer Margins,” Patent: U.S. patent pending, filed from UT Arlington on May 21, 2008.

4) Inventors: Britton Chance and Hanli Liu;Title: “Examination of scattering properties of biological tissue,” Patent: U. S. patent number: 6957094; issued on October 18, 2005.

5) Inventors: Cole A. Giller and Hanli Liu; Title: “Method and apparatus for probe localization in brain matter,” Patent: U.S. patent number: 6,567,690; issued on May 20, 2003.

6) Inventors: Britton Chance and Hanli Liu; Title: “Examination of biological tissue by monitoring one or more solutes,” Patent: U.S. patent number: 6,493,565; issued on Dec. 10, 2002.

7) Inventors: Britton Chance and Hanli Liu; Title: “Monitoring one or more solutes in a biological system using optical

techniques,” Patent: U.S. patent number: 5,782,755; issued on July 21, 1998.

8. PUBLICATIONS IN PEER-REVIEWED JOURNALS: (* means corresponding author for the paper)

1. Yueming Liu, Jianzhong Su, Zi-Jing Lin, Steven Teng, Natee Pantong, and Hanli Liu, “Reconstructions for Continuous-Wave Diffuse Optical Tomography by a Globally Convergent Method,” submitted to Journal of the Optical Society of America A, (April 2012).

2. Fenghua Tian, F. Andrew Kozel, Amarnath Yennu, Paul E. Croarkin, Shawn M. McClintock, Kimberly S. Mapes, Mustafa M. Husain, Hanli Liu*, “Test-retest reliability of functional near-infrared spectroscopy measurements associated with repetitive Transcranial Magnetic Stimulation,” submitted to Human Brain Mapping (April 2012).

Hanli Liu, BME8

http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=/netahtml/search-bool.html&r=3&f=G&l=50&co1=AND&d=ptxt&s1=Liu-Hanli&OS=Liu-Hanli&RS=Liu-Hanli





3. Vikrant Sharma, Shivaranjani Shivalingaiah, Yan Peng, David Euhus, and Hanli Liu*, “Auto-fluorescence lifetime and light reflectance spectroscopy for breast cancer diagnosis: potential tools for intra-operative margin detection,” in press Biomed. Opt. Express (2012).

4. Mary Cazzell*, Lin Li, Sonal J. Patel, Zi-Jing Lin, and Hanli Liu*, “Comparison of neural correlates of risk decision making between genders: An fNIRS study of Balloon Analogue Risk Task (BART),” NeuroImage in press (2012).

5. Venkaiah C. Kavuri, Zi-Jing Lin, Fenghua Tian, and Hanli Liu*, “Sparsity-enhanced Spatial Resolution and Depth Localization in Diffuse Optical Tomography,” Biomed. Opt. Express Vol. 3(5), 943-957 (2012).

6. Bilal Khan, Chester Wildey, Robert Francis, Fenghua Tian, Mauricio Delgado, Hanli Liu, Duncan MacFarlane, and George Alexandrakis, “Improving optical contact for functional infrared brain spectroscopy and imaging with brush optodes,” Biomed. Opt. Express Vol. 3(5), 878–898, (2012).

7. Ji-Wei He, Fenghua Tian, Hanli Liu*, and Yuan Bo Peng*, “Cerebrovascular Responses of the Rat Brain to Noxious Stimuli as Examined by Functional Near Infrared Whole Brain Imaging,” J Neurophysiol. Vol. 107, 2853–2865 (2012).

8. Ronak H. Patel, Aniket S. Wadajkar, Nimit L. Patel, Venkaiah C. Kavuri, Kytai T. Nguyen, Hanli Liu*, “Multifunctionality of indocyanine green-loaded biodegradable nanoparticles for enhanced optical imaging and hyperthermia intervention of cancer,” J. Biomed. Opt. 17(4), 046003 (2012).

9. Zi-Jing Lin, Haijing Niu, Lin Li, and Hanli Liu*, “Volumetric diffuse optical tomography for small animals using a CCD-camera-based imaging system,” International Journal of Optics 2012 (276367) 10 pages, (2012). doi:10.1155/2012/276367

10. Natee Pantong, Aubrey Rhoden, Shao-Hua Yang, Sandra Boetcher, Hanli Liu, and Jianzhong Su, “A Globally Convergent Numerical Method for Coefficient Inverse Problems for Thermal Tomography,” Applicable Analysis 90(10), 1573-1594 (2011).

11. Fenghua Tian, Bilal Khan, Haijing Niu, Khosrow Behbehani, George Alexandrakis, and Hanli Liu*, “Enhanced Functional Brain Imaging by Using Adaptive Filtering and a Depth Compensation Algorithm in Diffuse Optical Tomography,” IEEE Transactions on Medical Imaging Vol. 30 (6), 1239-1251 (2011).

12. Haijing Niu, Sabin Khadka, Fenghua Tian, Zijing Lin, Chunming Lu, Chaozhe Zhu, and Hanli Liu*, “Resting-state functional connectivity assessed with two diffuse optical tomographic systems,” J. of Biomed. Opt. Vol. 16(4), 046006 (2011).

13. Vikrant Sharma Jiwei He, Sweta Narvenkar, Yuan B Peng, and Hanli Liu*, “Quantification of light reflectance spectroscopy and its application: Determination of hemodynamics on the rat spinal cord and brain induced by electrical stimulation,” NeuroImage, Vol. 56, 1316–1328 (2011).

14. Dawen Zhao, Cheng-Hui Chang, Jae, G. Kim, Hanli Liu, Ralph P. Mason, “In vivo near-infrared spectroscopy and MRI monitoring of tumor response to Combretastatin A4

Hanli Liu, BME9


phosphate correlated with therapeutic outcome,” The International Journal of Radiation Oncology * Biology * Physics Vol. 80(2), 574–581 (2011).

15. Ji-Wei He, Dheerendra Kashyap, Lara A Trevino, Hanli Liu*, Yuan Bo Peng*, “Simultaneous absolute measures of glabrous skin hemodynamics and light scattering change in responses to formalin injection in rats,” Neuroscience Letters, Vol. 492, 59–63 (2011).

16. Han Zhang, Lian Duan, Yu-Jin Zhang, Chun-Ming Lu, Hanli Liu, Chao-Zhe Zhu, “Test-retest assessment of independent component analysis-derived resting-state functional connectivity based on functional near-infrared spectroscopy,” NeuroImage Vol. 55(2), 607-615 (2011).

17. Fenghua Tian, Mauricio R. Delgado, Sameer Dhamne, Bilal Khan, George Alexandrakis, Mario I. Romero, Linsley Smith, Dahlia Reid, Nancy J. Clegg, and Hanli Liu*, “Quantification of diffuse optical tomography for cortical reorganization in children with cerebral palsy,” Optics Express 18(25), 25973- 25986 (2010).

18. Christopher E. Hagains, Lara A. Trevino, Ji-Wei He, Hanli Liu, and Yuan B Peng, “Contributions of Dorsal Root Reflex and Axonal Reflex to Formalin-Induced Inflammation,” Brain Research, 1359, 90-97 (2010).

19. Fenghua Tian, Haijing Niu, Sabin Khadka, Zi-Jing Lin, and Hanli Liu*, “Algorithmic depth compensation improves quantification and noise suppression in functional diffuse optical tomography,” Biomed. Opt. Express, 1, 441-452 (2010).

20. Haijing Niu, Zi-jing Lin, Fenghua Tian, Sameer C. Dhamne, and Hanli Liu*, “Comprehensive investigation of three-dimensional diffuse optical tomography with depth compensation algorithm,” J. of Biomed. Opt., 15(4), 046005 (2010).

21. Michael V. Klibanov, Jianzhong Su, Natee Pantong, Hua Shan, and Hanli Liu, “A globally convergent numerical method for an inverse elliptic problem of optical tomography,” Applicable Analysis, 89(6), 861–891 (2010).

22. Bilal Khan, Fenghua Tian, Khosrow Behbehani, Mario Romero-Ortega, Mauricio R. Delgado, Nancy Clegg, Hanli Liu, George Alexandrakis, “Identification of abnormal motor cortex activation patterns in children with cerebral palsy by functional near infrared spectroscopy,” J. of Biomed. Opt. 15(3), 036008-1036008-14 (2010).

23. Haijing Niu, Fenghua Tian, Zijing Lin, and Hanli Liu*, “Development of a compensation algorithm for accurate localization of absorber depth in diffuse optical tomography,” Opt. Lett., 35 (3) 429-431 (2010).

24. Nimit L. Patel, Zi-Jing Lin, Yajuvendra Rathore, Edward H. Livingston, Hanli Liu, and George Alexandrakis, “Relative capacities of time-gated versus CW imaging to localize tissue embedded vessels with increasing depth,” J. of Biomed. Opt. 15(1), 016015-1016015-9 (2010).

25. Seoung B. Kim, Chivalai Temiyasathit, Karim Bensalah, Altug Tuncel, Jeffrey Cadeddu, Wareef Kabbani, Aditya V. Mathker, and Hanli Liu, “An efficient procedure for

Hanli Liu, BME10


classification of prostate cancer in optical spectra,” Expert Systems with Applications, 37(5), 3863-3869 (2010).

26. Fenghua Tian, Vikrant Sharma, F. Andrew Kozel, and Hanli Liu*, “Functional Near Infrared Spectroscopy to Investigate Hemodynamic Responses to Deception in the Prefrontal Cortex,” Brain Research, 1303, 120-130 (2009).

27. Fenghua Tian, Britton Chance, and Hanli Liu*, “Investigation of the Prefrontal Cortex in Response to Duration-Variable Anagram Tasks Using Functional Near Infrared Spectroscopy,” J. of Biomed. Opt. 14(5), 054016-1 to -11(2009).

28. Vikrant Sharma, Dheerendra Kashyap, Aditya Mathker, Sweta Narvenkar, Karim Bensalah, Wareef Kabbani, Altug Tuncel, Jeffrey A. Cadeddu, and Hanli Liu*, “Optical Reflectance Spectroscopy for Detection of Human Prostate Cancer,” Proc. of IEEE Engineering in Medicine and biology, 31st Annual International Conference of the IEEE EMBS, 118-121 (2009).

29. F. Andrew Kozel, Fenghua Tian, Sameer C. Dhamne, Paul Croarkin, Shawn M. McClintock, Alan Elliott, Kimberly Mapes, Mustafa M. Husain, and Hanli Liu, “Using Simultaneous Repetitive Transcranial Magnetic Stimulation/Functional Near Infrared Spectroscopy (rTMS/fNIRS) to Measure Brain Activation and Connectivity,” NeuroImage, 47, 1177–1184, (2009).

30. Fenghua Tian, George Alexandrakis and Hanli Liu*, “Optimization of probe geometry for diffuse optical brain imaging based on measurement density and distribution,” Applied Optics, 48(13), 2496-2504 (2009).

31. Natee Pantong, Jianzhong Su, Hua Shan, Michael V. Klibanov, and Hanli Liu, “A globally accelerated reconstruction algorithm for diffusion tomography with continuous-wave source in an arbitrary convex shape domain,” JOSA A 26(3), 456–472 (2009).

32. Cole A Giller, Hanli Liu, Dwight C German, Dheerendra Kashyap, Richard B Dewey, “A Stereotactic Near-Infrared Probe for Localization During Functional Neurosurgical Procedures: Further Experience,” J. of Neurosurgery 110, 263–273 (2009).

33. Edward H. Livingston, Praveen Gulaka, Sarita Kommera, Boping Wang, and Hanli Liu, “In-vivo spectroscopic characterization of porcine biliary tract tissues: first step in the development of new biliary tract imaging devices,” Annals of Biomedical Engineering, 37(1), 201-209 (2009).

34. Karim Bensalah, Disha Peswani, Altug Tuncel, Jay D. Raman, Ilia Zeltser, Hanli Liu and Jeffrey Cadeddu, “Optical Reflectance Spectroscopy to Differentiate Benign and from Malignant Renal Tumors at Surgery,” Urology 73(1), 178-181 (2009).

35. George Alexandrakis, Dharmendra Nadkar, Hanli Liu, and Edward H. Livingston, “Localization of adipose tissue embedded biliary tree vessels by use of near-infrared diffuse photon propagation models: A computational feasibility study,” Applied Optics 47(29), 5261-5271 (2008).

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36. Hua Shan, Michael V. Klibanov, Jianzhong Su, Natee Pantong, and Hanli Liu, “A globally accelerated numerical method for optical tomography with continuous wave source,” J. of inverse and ill-posed problems, 16, 765–792 (2008).

37. Karim Bensalah, Altug Tuncel, Disha Peshwani, Ilia Zeltser, Hanli Liu, and Jeffrey A. Cadeddu, “Optical reflectance spectroscopy to differentiate renal tumor from normal parenchyma,” J. of Urology 179(5), 2010-2013 (2008).

38. Hanli Liu*, Harsha Radhakrishnan, Arun Kumar Senapati, Christopher E Hagains, Disha Peswani, Aditya Mathker, and YuanBo Peng, “Acute responses in light scattering and hemoglobin oxygen saturation in rat spinal nerves during electrical and thermal stimulations,” NeuroImage 40, 217–227 (2008).

39. Jae G. Kim and Hanli Liu*, “Investigation of bi-phasic tumor oxygen dynamics induced by hyperoxic gas intervention: The dynamic phantom approach,” Applied Optics 47(2), 242-252 (2008).

40. Hua Shan, Michael V. Klibanov, Hanli Liu, Natee Pantong and Jianzhong Su, “Numerical implementation of the convexification algorithm for an optical diffusion tomograph,” Inverse Problems 24, 025006- (2008).

41. Mengna Xia, Shaohua Yang, James W. Simpkins and Hanli Liu*, “Noninvasive monitoring of estrogen effects against ischemic stroke in rats by near infrared spectroscopy,” Applied Optics 46(34), 8315-8321 (2007).

42. Jae G Kim and Hanli Liu*, “Variation of haemoglobin extinction coefficients can cause errors in determination of haemoglobin concentration measured by nearinfrared spectroscopy,” Phy sics in Med icine and Biol ogy 52, 6295–6322 (2007).

43. Ali Nawaz Bahadur, Cole A. Giller, Dheerendra Kashyap, and Hanli Liu*, “Determination of optical probe interrogation field of near-infrared reflectance: Phantom and Monte Carlo study,” Applied Optics 46(23), 5552-5561 (2007).

44. Harsha Radhakrishnan, Hanli Liu*, Arun Kumar Senapati, and Yuan Bo Peng*, “Determination of hemoglobin oxygen saturation in rat sciatic nerve by in vivo near infrared spectroscopy,” Brain Research 1098, 86-93 (2006).

45. Jianzhong Su, Hua Shan, Hanli Liu, and Michael V. Klibanov, “A Reconstruction Method with Data from A Multiple-Site, Continuous-Wave Source for 3 Dimensional Optical Tomography,” Journal of the Optical Society of America A 23(10), 2388-2395 (2006).

46. Mengna Xia, Vikram Kodibagkar, Hanli Liu*, and Ralph Mason*, “Tumor oxygen dynamics measured simultaneously by near-infrared spectroscopy and 19F magnetic resonance imaging in rats,” Phy sics in Med icine and Biol ogy 51, 45-60 (2006).

47. Maureen Johns, Cole A. Giller, Dwight C. German, and Hanli Liu*, “Determination of reduced scattering coefficient of biological tissue from a needle-like probe,” Optics Express 13(13), 4828-4842 (2005). http://www.opticsexpress.org/abstract.cfm?URI=OPEX-13-13-4828.

Hanli Liu, BME12

http://www.opticsexpress.org/abstract.cfm?URI=OPEX-13-13-4828


48. Yulin Song, Jae G. Kim, Ralph P. Mason, and Hanli Liu*, “Investigation of breast tumor oxygen consumption by near infrared spectroscopy,” J. of Physics D: Applied Physics 38, 2682-2690 (2005).

49. Jae G. Kim and Hanli Liu*, “Investigation of bi-phasic tumor oxygen dynamics induced by hyperoxic gas intervention: A numerical study,” Optics Express 13(12), 4465-4475 (2005).

http://www.opticsexpress.org/abstract.cfm?URI=OPEX-13-12-4465.

50. Yueqing Gu, Wei R. Chen, Mengna Xia, Sang W. Jeong, and Hanli Liu*, “Effect of Photothermal therapy on breast tumor vascular contents: non-invasive monitoring by near infrared spectroscopy,” Photochemistry and Photobiology 81(4), 1002–1009 (2005).

51. Harsha Radhakrishnan, Yuan Bo Peng, Arun Kumar Senapati, Dheerendra Kashyap, and Hanli Liu*, “Light scattering from rat spinal cord and sciatic nerves measured in vivo by near infrared reflectance spectroscopy,” J. of Biomed. Opt. 10(5) 051405(1-8) (2005).

52. Yueqing Gu, Ralph Mason, and Hanli Liu*, “Estimated fraction of tumor vascular blood contents sampled by near infrared spectroscopy and 19F magnetic resonance spectroscopy,” Optics Express 13(5), 1724-1733 (2005).http://www.opticsexpress.org/abstract.cfm?URI=OPEX-13-5-1724

53. Jae G. Kim, Mengna Xia, and Hanli Liu*, “Hemoglobin extinction coefficients: importance of correct value for near-infrared spectroscopy,” IEEE --Engineering in Medicine and Biology magazine, 24(2) 118-121 (2005).

54. Arun Kumar Senapati, Harsha Radhakrishnan, Hanli Liu*, Yuan Bo Peng*, “Detection of Degeneration in Rat Sciatic Nerve by in vivo Near Infrared Spectroscopy,” Brain Research Protocols, 14(2), 119-125 (2005).

55. Hanli Liu*, Yueqing Gu, Jae G. Kim, and Ralph P. Mason, “Near Infrared Spectroscopy and Imaging of Tumor Vascular Oxygenation,” Methods in Enzymology: Imaging, ed. by Michael Conn, vol. 385-386, pp. 349-378 (2004).

56. Zhiyu Qian, Sunder S. Victor, Yueqing Gu, Cole A. Giller, and Hanli Liu*, “ ‘Look-Ahead Distance’ of a fiber probe used to assist Neurosurgery: Phantom and Monte Carlo study,” Optics Express, 11(16) 1844-1855, (2003).

57. Yueqing Gu, Vincent Bourke, Jae Kim, Anca Constantinescu, Ralph P. Mason, Hanli Liu*, “Dynamic Response of Breast Tumor Oxygenation to Hyperoxic Respiratory Challenge Monitored with Three Oxygen-Sensitive Parameters,” Applied Optics, 42(16), 2960-2967 (2003).

58. Maureen Johns and Hanli Liu*, “Limited Possibility to Quantify Mean Particle Size by Logarithmic Light Scattering Spectroscopy,” Applied Optics, 42(16), 2968-2971 (2003).

59. C.A. Giller, H. Liu, P. P. Gurnani, S. Victor, U. Yazdani, and D. C. German, “Validation of a Near-Infrared Probe for Detection of Thin Intracranial White Matter Structures,” J. of Neurosurgery, 98, 1299-1306 (2003).

60. Jae Gwan Kim, Yulin Song, Dawen Zhao, Anca Constantinescu, Ralph P. Mason, and Hanli Liu*, “Interplay of Tumor Vascular Oxygenation and Tumor pO2 Observed Using Near

Hanli Liu, BME13

http://www.sciencedirect.com/science?_ob=IssueURL&_tockey=%23TOC%234951%232005%23999859997%23571623%23FLA%23display%23Volume_14,_Issue_2,_Pages_61-134_(February_2005)%23tagged%23Volume%23first%3D14%23Issue%23first%3D2%23date%23(February_2005)%23&_auth=y&view=c&_acct=C000059731&_version=1&_urlVersion=0&_userid=108428&md5=2a9fd05012e980410017e105cdd811a0




Infrared Spectroscopy, an Oxygen Needle Electrode, and 19F MR pO2 Mapping,” J. of Biomedical Optics 8(1), 53-62 (2003).

61. Maureen Johns, Cole A. Giller, and Hanli Liu*, “Determination of Hemoglobin Saturation in Blood-Perfused Tissues Using Reflectance Spectroscopy with Small Source-Detector Separations,” Applied Spectroscopy 55(12), 1686-1694 (2001).

62. Hanli Liu*, “Unified Analysis of the Sensitivities of Absorption and Pathlength to Scattering Variations in a Diffusive Medium,” Applied Optics 40(10), 1742-1746 (2001).

63. Cole A. Giller, Maureen Johns, and Hanli Liu, “Use of an Intracranial Near-Infrared Probe for Localization during Stereotactic Surgery for Movement Disorders,” J. of Neurosurgery 93, 498-505 (2000).

64. Hanli Liu*, Yulin Song, Katherine L. Worden, Xin Jiang, Anca Constantinescu, and Ralph P. Mason, “Noninvasive Investigation of Blood Oxygenation Dynamics of Tumors by Near Infrared Spectroscopy,” Applied Optics 39(28), 5231-5243 (2000).

65. Charles L. Matson and Hanli Liu, “Resolved object imaging and localization with the use of a backpropagation algorithm,” Optics Express 6(9), 168-174 (2000).

66. Hanli Liu*, Charles L. Matson, and Kelly Lau, “Experimental Validation of a Backpropagation Algorithm for Three-dimensional Breast Tumor Localization,” IEEE J. of Selected Topics in Quantum Electronics: Lasers in Medicine and Biology, 5(4), 1049-1057 (1999).

67. Charles L. Matson and Hanli Liu, “Backpropagation in turbid media,” Journal of the Optical Society of America A 16(6), 1254-1265 (1999).

68. T. Kitai, M. Miwa, H. Liu, B. Beauvoit, B. Chance, and Y. Yamaoka, “Application of near-infrared time-resolved spectroscopy to rat liver—a preliminary report for surgical application,” Physics in Medicine and Biology 44, 2049-2061 (1999).

69. Charles L. Matson and Hanli Liu, “Analysis of the Forward Problem with Diffuse Photon Density Waves in Turbid Media Using a Diffraction Tomographic Model,” Journal of the Optical Society of America A, 16(3), 455-466 (1999).

70. Maureen Johns, Cole A. Giller, and Hanli Liu*, “Theoretical and in vivo Investigation of Optical Reflectance from Human Brain to Assist Neurosurgery,” J. of Biomedical Optics 3(4), 437-445 (1998).

71. Y. Yang, H. Liu*, X. Li, and B. Chance, “A low cost frequency-domain photon migration instrument for tissue spectroscopy, oximetry, and imaging,” Optical Engineering 36(5), 1562-1569 (1997).

72. B. Chance, K. Kang, L. He, H. Liu, and S. Zhou, “Precision localization of hidden absorbers in body tissues with phased-array optical systems,” Rev. Sci. Instrum. 67(12) (1997).

73. H. Liu*, B. Beauvoit, M. Kimura, and B. Chance, “Dependence of tissue optical properties on solute-induced changes in refractive index and osmolarity,” J. of Biomedical Optics 1, 200-211 (1996).

Hanli Liu, BME14


74. A. H. Hielscher, H. Liu, B. Chance, F. K. Tittel, and S. L. Jacques, “Time Resolved Photon Emission from Layered Turbid Media,” Applied Optics 35, 719-728 (1996).

75. H. Liu*, D. A. Boas, Y. Zhang, A. G. Yodh, and B. Chance, “Determination of Optical Properties and Blood Oxygenation in Tissue Using Continuous Near Infrared Light,” Physics in Medicine and Biology 40, 1983-1993 (1995).

76. C. Dean Kurth, Hanli Liu, William Thayer, and Britton Chance, “A Dynamic Phantom Brain Model for Near-Infrared Spectroscopy,” Physics in Medicine and Biology 40, 2079-2092 (1995).

77. H. Liu*, A. H. Hielscher, F. K. Tittel, S. L. Jacques, and B. Chance, “Influence of Blood Vessels on the Measurement of Hemoglobin Oxygenation as Determined by Time-Resolved Reflectance Spectroscopy,” Medical Physics 22, 1209-1217 (1995).

78. B. Chance, H. Liu, T. Kitai, Y. Zhang, “Effects of Solutes on Optical Properties of Biological Materials: Models, Cells, and Tissues,” Anal. Biochem., 227, 351-362, (1995).

79. B. Beauvoit, H. Liu, K. Kang, P.D. Kaplan, M. Miwa, and B. Chance, “Characterization of Absorption and Scattering Properties for Various Yeast Strains by Time-Resolved Spectroscopy,” Cell Biophysics 23, 91-109 (1993).

80. B. Chance, Hanli Liu, and K. Kang, “Time Resolved Spectroscopy over Short Pathlengths of Small Absorber Scatterers,” published in Medical Optical Tomography: Functional Imaging and Monitoring , Gerhard J. Muller et al. eds., Vol. IS11, 545-549 (SPIE Optical Engineering Press, Bellingham, 1993).

81. H. Liu*, M. Miwa, B. Beauvoit, N.G. Wang, and B. Chance, “Characterization of Absorption and Scattering Properties of Small-Volume Biological Samples Using Time-Resolved Spectroscopy,” Anal. Biochem . 213, 378-385 (1993).

82. Hanli Liu, R. T. Williams, G. P. Williams, Jr, L. M. Slifkin, and C. Childs, “Hot Luminescence and Picosecond Relaxation Processes of Self-Trapped Excitons in KI and AgCl,” Proceedings of the XII International Conference on Defects in Insulating Materials ed. by O. Kanert and J.-M. Spaeth (World Scientific, New Jersey, 1993).

83. Mark W. Rowe, Hanli Liu, G. P. Williams, Jr., and R. T. Williams, “Picosecond Photoelectron Spectroscopy of Excited States at Si(111):B x R300, Si(111) 7x7, Si(100) 2x1, and Laser Annealed Si (111) 1x1 surfaces,” Phys. Rev. B 47, 2048-2064 (1993).

84. R. Gonzalez, Y. Chen, Hanli Liu, and R. T. Williams et al “Luminescence Properties in Deformed CaO Crystals,” Phys. Rev. B 47, 4910- (1993).

85. R. T. Williams, R. M. Wilson, and Hanli Liu, “Defects in Alkali Halides: Atomic Force Microscopy, Cluster Spectroscopy, and Ultrafast Time Resolution,” Nuclear Instruments and Methods in Physics Research B65, 473-483 (1992).

86. R. T. Williams, Hanli Liu, G. P. Williams, and Kevin J. Platt, “New Features of Self-Trapped-Exciton Luminescence in Rubidium Iodide,” Phys. Rev. Lett. 66, 2140-2144 (1991).

Hanli Liu, BME15


87. J. Wu, R. T. Williams, Hanli Liu, A. Wu, and C. Himes, “Single Shot Excimer Laser Ablation of Thick Polymer Resist on Metallic Substrates,” AMP Journal of Technology 1, 69- (1991).

88. R. T. Williams, Hanli Liu, and G. P. Williams, Jr, “Picosecond and subpicosecond optical spectroscopy for the study of F-center formation in KBr and RbBr at 296 K,” Reviews of Solid Science 4, 445-458 (1990).

89. V. M. Bermudez, R. T. Williams, Hanli Liu, G. P. Williams, Jr., and M. W. Rowe, “Photoemission study of the adsorption of nitric oxide on gallium arsenide (110) at low temperature,” J. Vac. Sci. Technol. A8, 1878- (1990).

9. PUBLICATION SUBMITTED FOR PEER-REVIEWED JOURNALS

1. Peter Leboulluec, Baohong Yuan, and Hanli Liu, “A compact and cost-efficient frequency-domain photoacoustic imaging technique,” submitted to American Journal of Physics (Jan. 2012).

2. Amarnath S Yennu, Sabin Khadka, Pritam Gautam, Pamela A. Tebebi, Fenghua Tian, and Hanli Liu*, “Investigation of frontoplar cortex under noxious pain stimuli using functional near infrared spectroscopy,” to be submitted to Biomedical Optics Express (Jan. 2012).

3. Venkaiah C. Kavuri, Zi-Jing Lin and Hanli Liu*, “Heterogeneous hierarchical segmentation method for improved prostate cancer imaging in diffuse optical tomography: simulation study,” submitted to JBO (Feb. 2012).

4. Vikrant Sharma, Payal Kapur, Ephrem Olweny, Jeffrey Cadeddu, Claus R Roehrborn, and Hanli Liu*, “Auto-fluorescence lifetime spectroscopy for prostate cancer detection: An optical biopsy approach,” to be submitted to European Urology (Feb. 2012).

1 0 . INVITED TALKS 1. Hanli Liu, “Clinical Applications of functional near infrared brain imaging:

Cerebrovascular responses under rTMS and cognitive assessment for neuropsychological tests,” Department of Psychiatry, University of Texas Southwestern Medical School at Dallas, Dallas, Jan. 5, 2012.

2. Hanli Liu, “Translation of fNIRS for clinical applications: objective assessment for pain perception and neuropsychological tests,” the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside, NIH, Bethesda, Maryland, Sept. 15-16, 2011.

3. Hanli Liu, “Functional Near Infrared Spectroscopy for Brain Imaging to Detect Pain Perception,” Cincinnati Children’s hospital, Cincinnati, Ohio, Sept. 6-7, 2011.

4. Hanli Liu, “Functional Near Infrared Spectroscopy and Functional Diffuse Optical Imaging,” Hong Kong University of Science and Technology, July 11, 2011.

5. Hanli Liu, “Clinical Applications of Diffuse Optical Tomography: cortical reorganization in children with cerebral palsy and study of connectivity under repetitive transcranial

Hanli Liu, BME16


magnetic stimulation,” Department of Physics, University of Pennsylvania, Philadelphia, PA, October 15, 2009.

6. Hanli Liu, invited to give a keynote speech for “Optical Methods as used for Molecular Imaging,” the Xiangshan Science Conferences (the 340th Session: Molecular Imaging and Its Applications), sponsored by the Ministry of Science and Technology of China (MOST), Beijing, P. R. China, Dec. 18-20, 2008.

7. Hanli Liu, “Ultrafast Gated Optical Imaging to Guide Cancer Surgery and Other Surgical Procedures,” SURGICAL RESEARCH ALLIANCE, Department of Surgery, University of Texas Southwestern Medical Center, Sept. 17, 2008.

8. Hanli Liu, “Diffuse Optical Imaging for Studying Neuro-activities,” National Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, August 14, 2008.

9. Hanli Liu, “Optical Spectroscopy and Diffuse Light Imaging: Applications to Cancer Research and Brain Functions,” Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Nov. 5, 2007.

10. Hanli Liu, “Optical Spectroscopy to detect positive cancer margins during laparoscopic surgery,” 7th UT Southwestern in vivo Cancer Cellular and Molecular Imaging, University of Texas Southwestern Medical Center at Dallas, Dallas, TX Oct. 16, 2007.

11. Hanli Liu, “Physics and Engineering of Optical Imaging,” Department of Physics, UT Arlington, Nov. 8, 2006.

12. Hanli Liu, “Recent Development on Novel Applications of Optical Spectroscopy and Imaging,” Beckman Laser Institute, UC Irvine, Irvine, CA, Sept. 14, 2006.

13. Hanli Liu, “Non Invasive and Minimally Invasive Characterization of Tumor Using Optical Methods,” Texas Cancer Registry, Texas Department of State Health Services, Mini-Educational Regional Conference, Fort Worth, Texas, July 14, 2006.

14. Hanli Liu, “Non-invasive Optical Brain Imaging,” the Mid-Cities Technical Club and the UTA College of Engineering, Arlington, TX, June 7, 2006.

15. Hanli Liu, “Non-invasive Optical Brain Imaging,” Gulf War Neuroimaging meeting, UTSW Medical Center at Dallas, Dallas, TX, June 13, 2006.

16. Hanli Liu, “Non-invasive Imaging for Cancer Prognosis and Therapy Monitoring for Stroke,” University of North Texas Health Sciences Center at Fort Worth, Fort Worth, TX, March 13, 2006.

17. Hanli Liu, “Near infrared tomography for cancer prognosis and therapy monitoring,” SPIE Medical Imaging International Conference, San Diego, California, 11 - 16 February 2006.

18. Hanli Liu, “Near Infrared Spectroscopy for Cancer Prognosis and Monitoring Drug Delivery,” Institute of Biological and Life Sciences, China Pharmaceutical University, Nanjing, China, July 1, 2005.

Hanli Liu, BME17


19. Hanli Liu, “Applications of Near Infrared Spectroscopy and Imaging in Medicine,” Biomedical Engineering Department, Nanjing University of Aeronautics and Astronautics, Nanjing, China, July 4, 2005.

20. Hanli Liu, “Near Infrared Spectroscopy and Imaging for diagnosis of Alzheimer's disease in vivo,” Department of Psychiatry, University of Texas Southwestern Medical Center, November 15, 2004.

21. Hanli Liu, “Near Infrared Spectroscopy and Imaging for Cancer Study and Brain Activities,” Department of Mechanical & Aerospace Engineering, UTA, October 29, 2004.

22. Hanli Liu, “Non-invasive Optical Spectroscopy and Imaging for Brain Function Measurements,” Behavioral and Brain Science, Callier Center for Communication Disorders, The University of Texas at Dallas, October 14, 2004.

23. Hanli Liu, “Diffusive Optical Imaging: a potential imaging tool for neuro-economics study,” Inter Disciplinary Center for Economics Sciences, George Mason University, Washington DC, Sept. 24, 2004.

24. Hanli Liu, “Light scattering from in vivo brain tissues and spinal cord determined by an NIR probe,” MR Center, Harvard Medical School, Boston, MA, December 19, 2003.

25. Hanli Liu, “Optical Spectroscopy and Imaging for Tissue Engineering,” Department of Biomedical Engineering, Rice University, Houston, TX, November 18, 2003.

26. Hanli Liu, “Near Infrared Spectroscopy and Imaging for Tumor Prognosis and Therapy Monitoring,” 4th Annual Symposium, Southwestern in vivo Cancer Cellular and Molecular Imaging Program, Dallas, Texas, November 17, 2003.

27. Hanli Liu, “The Physics of Biomedical Optical Imaging,” Department of Physics, Wake Forest University, Winston-Salem, NC, October 9, 2003.

28. Hanli Liu, “Optical Spectroscopy and Imaging for Neuroscience Applications,” Department of Pharmacology and Neuroscience, University of North Texas Health Sciences Center at Fort Worth, Fort Worth, TX, September 16, 2003.

29. Hanli Liu, “Optical Spectroscopy and Imaging for Tumor Oximetry and Assisting Neurosurgery in vivo,” National CLEO/QELS Annual Conference, Baltimore Convention Center, Baltimore, Maryland, June 3-4, 2003.

30. Hanli Liu, “Light scattering from living brain tissues and spinal cord measured in vivo by a needle NIR probe,” Department of Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, PA, April 18, 2003.

31. Hanli Liu, “Optical Imaging/Sensing with Near Infrared Light: from organ functions to cellular structures.” Department of Biomedical Engineering, Texas A&M University, College Station, Texas, March 25, 2003.

32. Hanli Liu, “Phantom and Computer Simulation for Tumor Hemodynamic Study,” Department of Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, PA, Nov. 18, 2002.

Hanli Liu, BME18


33. Hanli Liu, “Near-Infrared Spectroscopy Used in vivo for Assisting Neurosurgery and Tumor Oximetry,” Progress In Electromagnetics Research Symposium (PIERS) 2002, Cambridge, Massachusetts, July 1-5, 2002.

34. Hanli Liu "Optical Imaging/Sensing with Near Infrared Light: from organ functions to cellular structures" as a keynote speaker at the 7th Annual Biology-Chemistry Graduate Research Symposium of the University of Texas at Dallas, March 27, 2002.

35. Hanli Liu and Charles L. Matson, “3-D Localization and Characterization of Breast Tumors Using Diffraction Tomography,” International Symposia on Industrial Lasers and Biomedical Optics IL'99 and BiOS'99, Wuhan, China, October 25-27, 1999.

36. Hanli Liu, “Near Infrared Spectroscopy used in vivo for Assisting Neurosurgery and Tumor Oximetry,” International Symposia on Industrial Lasers and Biomedical Optics IL'99 andBiOS'99, Wuhan, China, October 25-27, 1999.

37. Charles L. Matson and Hanli Liu, “Resolution Issues in Optical Diffusion Tomography,” Light for Life, ICO Satellite Conference, Cancún, México, July 28-30, 1999.

38. Charles L. Matson and Hanli Liu, “Diffraction Tomography in Turbid Media: Theory and Applications,” OSA Annual National Conference, Baltimore, MD, October 1998.

39. Hanli Liu, “Biomedical Optics Research at UTA,” 16th Annual Houston Conference on Biomedical Engineering Research, Univ. of Houston, Houston, TX, April 1998.

40. Hanli Liu, “Near Infrared Technology and Current Biomedical Optics at UTA,” Radiology Department of Univ. of Texas Southwestern Medical School, Dallas, TX, April 1998.

41. Hanli Liu, “Physics and Engineering in Near Infrared Spectroscopy and Imaging of Tissue,” Physics Dept., Wake Forest University, North Carolina, Nov. 1997.

42. Hanli Liu, “Theory and Applications of Near Infrared Technologies,” Biomedical Engineering Program, Univ. of Texas at Austin, Austin, TX, Nov. 1996.

43. Hanli Liu, “Near Infrared Spectroscopy and Imaging of Tissue,” at Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, Dallas, TX, Oct. 1996.

1 1 . PROCEEDING PAPERS AND CONFERENCE PRESENTATIONS: 1. Fenghua Tian, Alexa Smith-Osborne, Amarnath Yennu, and Hanli Liu, “Assessments of

posttraumatic stress disorder by functional near infrared spectroscopy: A preliminary report,” accepted for presentation at OSA Optics Photonics Congress, Miami, Florida, April 29-May 3, 2012.

2. Vikrant Sharma, Payal Kapur, Ephrem Olweny, Jeffrey Cadeddu, Claus R Roehrborn, and Hanli Liu, “Auto-fluorescence lifetime spectroscopy for prostate cancer detection: An

optical biopsy approach,” accepted for presentation at OSA Optics Photonics Congress, Miami, Florida, April 29-May 3, 2012.

3. Vikrant Sharma, Shivaranjani Shivalingaiah, Yan Peng, David Euhus, and Hanli Liu, “Light reflectance spectroscopy and auto-fluorescence lifetime: potential tools for intra-operative

breast cancer margin detection,” accepted for presentation at OSA Optics Photonics Congress, Miami, Florida, April 29-May 3, 2012.

Hanli Liu, BME19


4. Venkaiah C. Kavuri, Zi-Jing Lin and Hanli Liu, “Heterogeneous Hierarchical Segmentation Method for Improved Prostate Cancer Imaging In Diffuse Optical Tomography: Simulation Study,” accepted for presentation at OSA Optics Photonics Congress, Miami, Florida, April 29-May 3, 2012.

5. Venkaiah C. Kavuri, Zi-Jing Lin, and Hanli Liu, “Comparison of L1 and L2 regularizations in diffuse optical Tomography,” accepted for presentation at OSA Optics Photonics Congress, Miami, Florida, April 29-May 3, 2012.

6. Zi-Jing Lin, Ming Ren, Lin Li, Shaohua Yang, and Hanli Liu, “Diffuse Optical Tomography to Study Ischemia stroke in Pre-clinical Rat Models,” accepted for presentation at OSA Optics Photonics Congress, Miami, Florida, April 29-May 3, 2012.

7. Lin Li, Zi-Jing Lin, Mary Cazzell, and Hanli Liu, “Measurement of brain activations to examine gender-specific risk decision making using functional near infrared spectroscopy (fNIRS),” accepted for presentation at OSA Optics Photonics Congress, Miami, Florida, April 29-May 3, 2012.

8. Jixing Yao, Fenghua Tian, Soontorn Oraintara, and Hanli Liu, “Novel method to improve 2D DOT spatial resolution using l1-regularization and noise-normalization,” accepted for presentation at OSA Optics Photonics Congress, Miami, Florida, April 29-May 3, 2012.

9. Fenghua Tian, Joshua Koch, Joseph M. Forbess, Katrina Vandebruinhorst, Dorothy Kelly, and Hanli Liu, “Assessments of cerebral blood volume and oxygenation asymmetry in neonatal cardiopulmonary bypass by near infrared spectroscopy,” accepted for presentation at OSA Optics Photonics Congress, Miami, Florida, April 29-May 3, 2012.

10. Fenghua Tian, Haijing Niu, Sabin Khadka, Zi-Jing Lin and Hanli Liu, “Algorithmic depth compensation improves transverse resolution and quantification in functional diffuse optical tomography,” SPIE, Photonics West, BiOS Biomedical Optics Symposium, presentation 7896-82, Jan. 23-26, 2011, San Francisco, California.

11. Fenghua Tian, Haijing Niu, Bilal Khan, George Alexandrakis, Khosrow Behbehani, and Hanli Liu, “Adaptive cancellation of spontaneous fluctuations in combination with depth compensation algorithm enhances real-time brain imaging in diffuse optical tomography,” SPIE, Photonics West, BiOS Biomedical Optics Symposium, oral presentation, paper 7896-6, Jan. 23-26, 2011, San Francisco, California.

12. Vikrant Sharma, Nimit Patel, and Hanli Liu, “Optical Biopsy using light reflectance spectroscopy for Prostate cancer diagnosis,” SPIE, Photonics West, BiOS Biomedical Optics Symposium, oral presentation, paper 7883B-42, Jan. 23-26, 2011, San Francisco, California.

13. Vikrant Sharma and Hanli Liu, “Characterization of 2-D surface imaging of tissue optical properties using a sub millimeter fiber optic probe,” Proc. of SPIE, Vol. 7896, 789636-7 (2011).

14. Haijing Niu, Lin Li, Gauri Suresh Bhave, Zi-Jing Lin, Fenghua Tian, Rong Zhang, Khosrow Behbehani, and Hanli Liu,“Functional Brain Imaging and Cerebral Metabolic Rate of Oxygen during Squat-Stand Protocols,” SPIE, Photonics West, BiOS Biomedical Optics Symposium, oral presentation, paper 7898-25, Jan. 23-26, 2011, San Francisco, California.

Hanli Liu, BME20


15. Zi-Jing Lin, Haijing Niu, Lin Li, Hanli Liu, “CCD-camera-based diffuse optical tomography to study ischemic stroke in pre-clinical rat models,” Proc. of SPIE, Vol. 7896, 78960R (2011).

16. Nimit Patel, Aniket Wadajkar, Ronak Patel, Kytai Nguyen, and Hanli Liu, “Synthesis and characterization of Indocyanine Green embedded biodegradable-biocompatible polymeric (PLGA) nanoparticles for prostate cancer imaging,” SPIE, Photonics West, BiOS Biomedical Optics Symposium, oral presentation, paper 7910-34, Jan. 23-26, 2011, San Francisco, California.

17. Venkaiah C Kavuri, Zi-Jing Lin and Hanli Liu, “Hierarchical segmentation for improved image reconstruction in diffuse optical tomography of human prostate cancer,” SPIE, Photonics West, BiOS Biomedical Optics Symposium, oral presentation, paper 7896-77, Jan. 23-26, 2011, San Francisco, California.

18. Sabin Khadka, Shrujan Reddy Chityala, Fenghua Tian, Hanli Liu, “Identification of prefrontal cortex activation while performing Stroop test using diffuse optical tomography,” Proc. of SPIE, Vol. 7883, 78834B, (2011).

19. Bilal Khan, Chester Wildey, Robert Francis, Fenghua Tian, Mario I. Romero, Mauricio R. Delgado, Nancy J. Clegg, Linsley Smith, Hanli Liu, Duncan L. MacFarlane, George Alexandrakis, “Functional near infrared brain imaging with a brush-fiber optode to improve optical contact on subjects with dense hair,” SPIE, Photonics West, BiOS Biomedical Optics Symposium, oral presentation 7883G-136, Jan. 23-26, 2011, San Francisco, California.

20. Fenghua Tian, Sameer Dhamne, George Alexandrakis, F. Andrew Kozel, Mauricio R. Delgado, and Hanli Liu, “Spatiotemporal Analysis Developed for Functional Diffuse Optical Imaging and its Clinical Applications,” presented at OSA Optics Photonics Congress, Miami, Florida, April 11-14, 2010.

21. Zi-Jing Lin, Haijing Niu and Hanli Liu, “Feasibility Study of Volumetric Diffuse Optical Tomography in Small Animal Using CCD-camera-based Imaging System,” presented at OSA Optics Photonics Congress, Miami, Florida, April 11-14, 2010.

22. Nimit Patel, Ajay Chalukunnil, Jian Yang, Bumsoo Han, Hanli Liu and George Alexandrakis, “Characterization of a novel biodegradable photoluminescent polymer for lifetime dependent thermometry in tissues,” presented at OSA Optics Photonics Congress, Miami, Florida, April 11-14, 2010.

23. Haijing Niu, Zi-Jing Lin, Fenghua Tian, Sameer Dhamne, and Hanli Liu, “Three-dimensional Diffuse Optical Tomography in the Human Brain,” presented at OSA Optics Photonics Congress, Miami, Florida, April 11-14, 2010.

24. Yajuvendra Rathore, Nimit Patel, Hanli Liu, and George Alexandrakis, “Exploratory study of gold nanoshell as a therapeutic thermal ablation agent for cancer treatment using laboratory and animal tissue phantoms,” presented at OSA Optics Photonics Congress, Miami, Florida, April 11-14, 2010.

25. Venkatagiri Krishnamurthy, Venkaiah Kavuri , Fenghua Tian, and Hanli Liu, “Detectability of hemodynamic response to thermal pain in pre-frontal cortex using Diffuse Optical Tomography,” presented at OSA Optics Photonics Congress, Miami, Florida, April 11-14, 2010.

Hanli Liu, BME21


26. Fenghua Tian, Haijing Niu, and Hanli Liu, “Optimization of 2D Spatial Resolution for Diffuse Optical Imaging of Brain Function,” presented at OSA Optics Photonics Congress, Miami, Florida, April 11-14, 2010.

27. Vikrant Sharma, Jiwei He, Sweta Narvenkar, Yuan Bo Peng, and Hanli Liu, “Multi-Channel, Light Reflectance Spectroscopy for Fast Detection of Hemodynamic Changes on the Spinal Cord and Brain Induced by Electrical Stimulations in Rats,” presented at OSA Optics Photonics Congress, Miami, Florida, April 11-14, 2010.

28. He J-W, Tian F, Liu H, Peng YB, “Comparisons of the brain fNIR signals between with and without scalp in responses to peripheral stimuli,” Society for Neuroscience Abstract, 74.4/X11, 2009.

29. Hagains CE, Huntington PJ, Senapati AK, Wilson HD, Fuchs PN, Liu H, Peng YB, “Effects of spinal nerve ligation on cutaneous blood flow in rats,” Society for Neuroscience Abstract, 561.8/DD6, 2009.

30. Herath PM, Hagains CE, He J-W, Davis MA, Liu H, Peng YB, “The role of periaqueductal gray induced dorsal root reflexes in cutaneous neurogenic inflammation,” Society for Neuroscience Abstract, 268.19/BB25, 2009.

31. Vikrant Sharma, Jiwei He, Sweta narvenkar, Dheerendra Kashyap, Yuan Bo Peng, and Hanli Liu, “Quantification of Optical Properties of Tissue and Its Application to Study of Pain Mechanism in Rats,” oral presentation given in SPIE, Photonics West, BiOS Biomedical Optics Symposium, January 24-29, 2009, San Jose, California.

32. George Alexandrakis, Khosrow Behbehani, Fenghua Tian, Bilal Khan, Nayan Asanani, Mauricio Delgado, and Hanli Liu, “Translation of Near Infrared Brain Imaging to Assess Children with Cerebral Palsy,” oral presentation given in SPIE, Photonics West, BiOS Biomedical Optics Symposium, January 24-29, 2009, San Jose, California.

33. R. Parlapalli, V. Sharma, K.S. Gopinath, R.W. Briggs, and H. Liu, “Comparison of hemodynamic response non-linearity using simultaneous near infrared spectroscopy and magnetic resonance imaging modalities,” Proceedings of the SPIE, 7171, 71710P-71710P-12 (2009).

34. Aditya V. Mathker, Karim Bensalah, Wareef Kabbani, Altug Tuncel, Jeffrey Cadeddu, and Hanli Liu, “Optical Reflectance Spectroscopy for Detection of Human Prostate and Kidney Cancer,” paper 7161B-208, oral presentation given in SPIE, Photonics West, BiOS Biomedical Optics Symposium, January 24-29, 2009, San Jose, California.

35. Fenghua Tian, Britton Chance, and Hanli Liu, “Investigation of the Prefrontal Cortex in Response to Duration-flexible Anagram Tasks Using Functional Near Infrared Spectroscopy,” oral presentation given in SPIE, Photonics West, BiOS Biomedical Optics Symposium, January 24-29, 2009, San Jose, California.

36. Fenghua Tian, Frank Andrew Kozel, Shawn McClintock, Sameer Dhamne, Kimberly Mapes, Mustafa M. Husain, and Hanli Liu, “Bilateral Responses of Prefrontal and Motor Cortices to Repetitive Transcranial Magnetic Stimulation as measured by Functional Near Infrared Spectroscopy,” oral presentation given in SPIE, Photonics West, BiOS Biomedical Optics Symposium, January 24-29, 2009, San Jose, California.

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37. George Alexandrakis, Nimit Patel, Pavan Rajamahendravarapu, Zi-Jing Lin, Hanli Liu, “Relative capacities of time-gated versus CW imaging to localize tissue embedded vessels with increasing depth,” oral presentation given in SPIE, Photonics West, BiOS Biomedical Optics Symposium, January 24-29, 2009, San Jose, California.

38. Zi-Jing Lin, George Alexandrakis, Nimit Patel, and Hanli Liu, “Time-gated optical imaging to detect positive prostate cancer margins,” oral presentation given in SPIE, Photonics West, BiOS Biomedical Optics Symposium, January 24-29, 2009, San Jose, California.

39. F. Andrew Kozel, Fenghua Tian, Sameer Dhamne, Paul Croarkin, Shawn M. McClintock, Alan Elliott, Kimberly Mapes, Mustafa M. Husain, and Hanli Liu, “Using functional Near Infrared Spectroscopy (fNIRS) to measure brain changes associated with repetitive Transcranial Magnetic Stimulation (rTMS) of the Motor and Prefrontal Cortices,” The ACNP (American College of NeuroPsychopharmacology) Annual Meeting, Cottsdale, Arizona, December 7-11, 2008.

40. Jiwei He, Fenghua Tian, Hanli Liu, and Yuan B. Peng, “Detection of Hemodynamic Changes in the Brain by Near Infrared Spectroscopy during Mechanical and Chemical Noxious Stimuli,” Neuroscience 2008, the Society for Neuroscience's 38th annual meeting, Nov. 15-19, 2008, Washington, DC.

41. Fenghua Tian, Suresh Prajapati, and Hanli Liu, "A Location-Adaptive, Frequency-Specific Cancellation Algorithm to Improve Optical Brain Functional Imaging," presented at OSA Optics Photonics Congress, BMD29, St. Petersburg, Florida, March 16-19, 2008.

42. Fenghua Tian, Mauricio R. Delgado, Nancy J. Clegg, Mario I. Romero-Ortega, and Hanli Liu, "Investigation of the Motor Cortex Function in Children with Cerebral Palsy Using Functional Near-infrared Spectroscopic Imaging," presented at OSA Optics Photonics Congress, PDPBTuG3, St. Petersburg, Florida, March 16-19, 2008.

43. Renuka Parlapalli, Fenghua Tian, Vikrant Sharma, Suresh Prajapati, and Hanli Liu, "Spatial and temporal resolution comparison of two CW diffuse optical imagers," presented at OSA Optics Photonics Congress, BMD50, St. Petersburg, Florida, March 16-19, 2008.

44. Vikrant Sharma, Gopinath Kaundinya, Renuka Parlapalli, Richard Briggs, and Hanli Liu, "Non-linearity of Hemodynamic Response in Motor Cortex Measured by Near Infrared Spectroscopy," presented at OSA Optics Photonics Congress, BMD13, St. Petersburg, Florida, March 16-19, 2008.

45. Aditya V. Mathker, Dheerendra Kashyap, Disha L. Peswani, Karim Bensalah, Wareef Kabbani, Altug Tuncel, Jeffrey Cadeddu, and Hanli Liu, “Optical Reflectance Spectroscopy for Detection of Renal Cell Carcinoma Using Model-Driven Analysis,” presented at OSA Optics Photonics Congress, BTuF43, St. Petersburg, Florida, March 16-19, 2008.

46. Disha L. Peswani, Aditya Mathker, Dheerendra Kashyap, Karim Bensalah, Altug Tuncel, Wareef Kabbani, Jeffrey Cadeddu, Jung Hun Oh, Jean Gao, and Hanli Liu, “Feasibility of Detecting Prostate Adenocarcinoma Using Optical Reflectance Spectroscopy,” presented at OSA Optics Photonics Congress, BTuF44, St. Petersburg, Florida, March 16-19, 2008.

47. Dheerendra Kashyap, Disha Peswani, Jeffrey Cadeddu, Hanli Liu, “Steady-state reflectance spectroscopy used to quantify hemodynamic and optical properties of tissue: Demonstration

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of heterogeneities of human prostrates,” presented at OSA Optics Photonics Congress, BSuE80, St. Petersburg, Florida, March 16-19, 2008.

48. Fenghua Tian, Rhonda Dobbs, Alejandro del Carmen, Frank Andrew Kozel and Hanli Liu, “Can Functional Near-infrared Spectroscopic (fNIRS) Imaging Detect Deception?” presented at OSA Optics Photonics Congress, BTuE4, St. Petersburg, Florida, March 16-19, 2008.

49. Hua Shan, Natee Pantong, Jianzhong Su, Hanli Liu and Michael V. Klibanov, “Globally Convergent Reconstruction Algorithm for Diffusion Tomography of Prostate,” presented at OSA Optics Photonics Congress, BSuE33, St. Petersburg, Florida, March 16-19, 2008.

50. Praveen Kumar Gulaka, Sarita Kommera, Boping Wang, Edward Livingston, and Hanli Liu, “A Novel Spectroscopic Approach to Localize Billary Tract Tissues During Laparoscopic Cholecystectomy,” presented at Houston Society for Engineering in Medicine and Biology (HSEMB 2007) February 8, 2007.

51. D. Kashyap, D. L. Peswani, J. Cadeddu and H. Liu, “Heterogeneities in Concentrations of Hemoglobin Derivatives and Oxygen Saturations in Human Prostate Tumors Evaluated by NIRS,” presented at Houston Society for Engineering in Medicine and Biology (HSEMB 2007) February 8, 2007.

52. Feraydune Kashefi, Donald E. Watenpaugh, and Hanli Liu, “Obstructive Sleep Apnea Screening by NIRS Imaging,” Proc. SPIE Int. Soc. Opt. Eng. 6434 (2007).

53. Dheerendra Kashyap, Vikrant Sharma, and Hanli Liu, “Non-invasive monitoring of hemodynamic changes in orthotropic brain tumor,” Proc. SPIE Int. Soc. Opt. Eng. 6434, 643408 (2007).

54. Dheerendra Kashyap, Nguvenvu Chu, Aditya Apte, BoPing Wang, and Hanli Liu, “Development of broadband multi-channel NIRS (near-infrared spectroscopy) imaging system for quantification of spatial distribution of hemoglobin derivatives,” Proc. SPIE Int. Soc. Opt. Eng. 6434, 64341X (2007).

55. Manan Goel, Harsha Radhakrishnan, Liping Tang, and Hanli Liu, “Application of Near Infrared Multi-spectral CCD Imager to Determine the Hemodynamic Changes in Prostate Tumor.” presented at Biomedical Optics Topical Meeting, Fort Lauderdale, Florida, March 19-23, 2006.

56. Dheerendra kashyap and Hanli Liu, “Absolute Quantification of Hemoglobin Derivative Concentrations and Reduced Scattering Coefficients from Turbid Media using Steady State Reflectance Spectroscopy with Single Source-Detector Separation,” presented at Biomedical Optics Topical Meeting, Fort Lauderdale, Florida, March 19-23, 2006.

57. Vikrant Sharma, Pradheep Raman, Anna Ratka, and Hanli Liu, “Application of Near Infrared Spectroscopy to Study Hot Flashes in Women,” presented at Biomedical Optics Topical Meeting, Fort Lauderdale, Florida, March 19-23, 2006.

58. Jianzhong Su, Hua Shan, Hanli Liu, and Michael V. Klibanov, “A Simplified Globally Convergent Reconstruction Method for 3 Dimensional Optical Tomography,” presented at Biomedical Optics Topical Meeting, Fort Lauderdale, Florida, March 19-23, 2006.

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59. Jae G. Kim and Hanli Liu, Dawen Zhao and Ralph P. Mason, “Acute effects of combreatastatin A4 phosphate on breast tumor hemodynamics monitored by near infrared spectroscopy,” presented at Biomedical Optics Topical Meeting, Fort Lauderdale, Florida, March 19-23, 2006.

60. Mengna Xia, Hanli Liu, Ya Ren, Ralph Mason, Benjamin Levine, “Simultaneous monitoring of tumor vascular and tissue oxygen tension under hyperbaric oxygen exposure,” presented at Biomedical Optics Topical Meeting, Fort Lauderdale, Florida, March 19-23, 2006.

61. Manan Goel, Harsha Radhakrishnan, Hanli Liu, and Yuan Bo Peng, “In vivo detection of intrinsic optical signal changes in rat spinal cord due to formalin using a multi-wavelength CCD camera,” presented at Biomedical Optics Topical Meeting, Fort Lauderdale, Florida, March 19-23, 2006.

62. Harsha Radhakrishnan, Hanli Liu, Arun K Senapati, Christopher E Hagains, and Yuan Bo Peng, “Detection of changes in rat spinal cord due to peripheral stimulation using NIR reflectance spectroscopy,” presented at Biomedical Optics Topical Meeting, Fort Lauderdale, Florida, March 19-23, 2006.

63. Bo P. Wang, Aditya Apte, and Hanli Liu, “Effective Algorithms for Optical Tomography,” accepted for oral presentation in the International SIAM (Society of Industrial and Applied Mathematics) Conference on Optimization, May 15-19, 2005 at Norra Latin, City Conference Centre in Stockholm, Sweden.

64. Jae G. Kim, Dawen Zhao, Ralph P. Mason, and Hanli Liu, “Chemotherapeutic (Cyclophosphamide) Effects on Breast Tumor Hemodynamics Monitored by Multi-Channel NIRS,” presented in SPIE, Photonics West, San Jose, CA, Jan. 23-27, 2005.

65. Mengna Xia, Ralph Mason, and Hanli Liu, “Noncontact Optical Image Fusion of Breast Tumor Phantoms with Near-infrared and Bioluminascence Light,” presented in SPIE, Photonics West, San Jose, CA, Jan. 23-27, 2005.

66. Harsha Radhakrishnan, Arun K Senapati, Dheerendra R Kashyap, Yuan B Peng, and Hanli Liu, “NIR reflectance spectroscopy as a novel method to detect demyelination in rat sciatic nerve in-vivo,” presented in SPIE, Photonics West, San Jose, CA, Jan. 23-27, 2005.

67. Raghavender Ranga, Dheerendra Kashyap, Khosrow Behbehani, Hanli Liu, “An in vitro hemodynamic tissue model to study the variations in flow using NIRS,” presented in SPIE, Photonics West, San Jose, CA, Jan. 23-27, 2005.

68. Dheerendra R Kashyap, Cole Giller and Hanli Liu, “Particle size determination using near infrared reflectance and small source-detector separation in turbid media,” presented in SPIE, Photonics West, San Jose, CA, Jan. 23-27, 2005.

69. Monica S. Allen, Jeffery W. Allen, Shweta Mikkilineni, and Hanli Liu “Trends in cerebral oxygenation during mental and physical exercises measured using near-infrared spectroscopy (NIRS) – potential for early detection of Alzheimer’s disease,” presented in SPIE, Photonics West, San Jose, CA, Jan. 23-27, 2005.

70. Jae G. Kim and Hanli Liu, “Investigation of breast tumor hemodynamics using tumor vascular phantoms and FEM simulations,” OSA Biomedical Topical Meetings, in Biomedical Topical Meetings on CD-ROM (The Optical Society of America, Washington, DC, 2004), WF16.

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71. Mengna Xia, Yueqing Gu, Hanli Liu, Vikram Kodibagkar, Anca Constantinescu, Ralph Mason, “Tumor oxygen dynamics measured simultaneously by near-infrared spectroscopy and MR EPI imaging,” in Biomedical Topical Meetings on CD-ROM (The Optical Society of America, Washington, DC, 2004), ThF33.

72. Yueqing Gu, Mengna Xia, Hanli Liu, Vikram Kodibagkar, Anca Constantinescu, Ralph P. Mason, “Correlation of NIR spectroscopy with BOLD MR imaging of assessing breast tumor vascular oxygen status,” in Biomedical Topical Meetings on CD-ROM (The Optical Society of America, Washington, DC, 2004), FB6.

73. Tony Chang, Vikrant Sharma, Della Varghese, Hanli Liu, “NIR Brain Physiological Study in Response to Breath Holding,” presented at OSA Biomedical Topical Meetings, Technical Digest, SuH5, Miami Beach, FL, April 14-17, 2004.

74. V. A. Bourke, Y Gu, A. Constantinescu, H. Liu and R. P. Mason, "Dynamic Optical Interrogation Of Oxygenation In The Tumor Microenvironment", The Eighth International Conference on Tumor Microenvironment and Its Impact on Cancer Therapies, Miami (South Beach), Florida, May, 2003.

75. Y. Song, K. L.Worden, X. Jiang, D. Zhao, A. Constantinescu, H. Liu and R. P. Mason, “Tumor Oxygen Dynamics: Comparison between 19F MR-EPI of hexafluorobenzene and Frequency Domain NIR Spectroscopy,” Oxygen Transport to Tissue XXIV. Proceedings of the 27th annual meeting of the International Society on Oxygen Transport to Tissue. (Dunn, J. F. and H. M. Swartz Eds.), Advances in Experimental Medicine and Biology 530, Kluwer Acad. New York, pp225-236 (2003).

76. Jae G. Kim, Yueqing Gu, Anca Constantinescu, Ralph P. Mason, Hanli Liu, “Non-Uniform Tumor Vascular Oxygen Dynamics Monitored By Three-Channel Near-Infrared Spectroscopy”, Proc. SPIE-Int. Soc. Opt. Eng. 4955, 388-396 (2003).

77. Maureen Johns and Hanli Liu, “Calculating the reduced scattering coefficient of turbid media from a single optical reflectance signal,” presented in SPIE, Photonics West, San Jose, CA, Jan. 26-29, 2003.

78. Yueqing Gu, Vikram Kodibagkar, Mengna Xia, Zhiyu Qian, Jae. G. Kim, Anca Constantinescu, Ralph P. Mason, Hanli Liu “Simultaneous determination of breast tumor vascular oxygenation and blood volume measured with near infrared spectroscopy and 19F MRS and 1H MRI,” presented in SPIE, Photonics West, San Jose, CA, Jan. 26-29, 2003.

79. Jae G. Kim, Yuling Song, Hanli Liu, Anca Constantinescu, and Ralph P. Mason, "Investigation of tumor oxygen consumption and tumor vascular oxygen dynamics in response to pharmacological interventions by NIRS," OSA Biomedical Topical Meetings, Technical Digest, SuH2, Miami Beach, FL, April 7-10, 2002.

80. Yulin Song, Yueqing Gu, Jae G. Kim, Hanli Liu, Anca Constantinescu, and Ralph P. Mason, “Correlation between total hemoglobin concentration and blood volume of breast tumors measured by NIR spectroscopy and 19F MRS of PFOB,” OSA Biomedical Topical Meetings, Technical Digest, SuH5, Miami Beach, FL, April 7-10, 2002.

81. Prem Gurnani, Maureen Johns, Dheerendra Kashyap, Dwight German, Cole Giller, and Hanli Liu, “Determination of mean size of effective scatterers by a small optical probe for

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brain structures,” OSA Biomedical Topical Meetings, Technical Digest, MH4, Miami Beach, FL, April 7-10, 2002.

82. M. Johns, C. A. Giller, and Hanli Liu, “Calculation of Hemoglobin Saturation from in vivo Human Brain Tissues Using a Modified Diffusion Theory Model,” Proc. SPIE-Int. Soc. Opt. Eng. 4254, 194-203 (2001).

83. J. G. Kim, Y. Song, D. Zhao, A. Constantinescu, R. P. Mason, and Hanli Liu, “Interplay of Tumor Vascular Oxygenation and pO2 in Tumors Using NIRS and Needle Electrode,” Proc. SPIE-Int. Soc. Opt. Eng. 4250, 429-436 (2001).

84. Hanli Liu, M. Johns, and C. A. Giller, “Modified diffusion models for steady-state broadband reflectance with a needle-like optic probe,” Proc. SPIE-Int. Soc. Opt. Eng. 4250, 76-81 (2001).

85. Hanli Liu, Yulin Song, Katherine L. Worden, Anca Constantinescu, and Ralph P. Mason, “Noninvasive measurement of tumor hemoglobin dynamics using near-infrared spectroscopy,” OSA Biomedical Topical Meetings TOPS 38, 464-466 (2000).

86. Hanli Liu and Charles L. Matson, “Resolution Issues and Characterization in Optical Diffraction Tomography,” OSA Biomedical Topical Meetings, TOPS 38, 478-480 (2000).

87. Y. Song, X. Jiang, D. Zhao, A. Constantinescu, H. Liu, and R. P. Mason, “Regional Tumor Tissue pO2 and Blood sO2: Comparison of 19F MR EPI and Frequency Domain NIR Spectroscopy,” Proc. Intl. Soc. Mag. Reson. Med 8, 1039 (2000).

88. D. Wawro, S. Tibuleac, R. Magnusson, and H. Liu, “Optical fiber endface biosensor based on resonances in direlectric waveguide gratings,” SPIE Biomedical Optics'2000, San Jose, CA, 22-28 January 2000.

89. Hanli Liu, Cole. A. Giller, and Maureen Johns, “Tumor Brain Structural Mapping and Localization During Stereotactic Surgery for Movement Disorders Using Optical Reflectance Spectroscopy,” presented at Inter-Institute Workshop on In Vivo Optical Imaging at the NIH, Bethesda, MD, Sept. 16-17, 1999.

90. Charles L. Matson, Hanli Liu, Barbara T. Landesman, and Ryan Christopher, “Imaging and localization in turbid media,” in Optics in Atmospheric Propagation and Adaptive Systems III, A. Kohnle and J.D. Gonglewski, eds., Proceedings of the SPIE 3866, 74-81 (1999).

91. Y. Song, K.L. Worden, X. Jiang, D. Zhao, A. Constantinescu, H. Liu, and R.P. Mason, “Tumor Oxygen Dynamics: Comparison between 19F MR-EPI of Hexafluorobenzene and Frequency Domain NIR Spectroscopy,” International Society on Oxygen Transport to Tissue, Hanover, NH, August 28-Sept. 3, 1999.

92. Hanli Liu and C. L. Matson, “3-D Localization and Characterization of Breast Tumors Using Diffraction Tomography,” SPIE Biomedical Optics'99, San Jose, CA, 23-29 January 1999.

93. M. Johns, C. A. Giller, and Hanli Liu, “In-vivo Optical Reflectance Measurement of brain with Calculation of Absorption and Scattering Coefficients,” Proc. SPIE-Int. Soc. Opt. Eng. 3595, 70-78 (1999).

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94. K. L. Worden, Y. Song, R. P. Mason, and Hanli Liu, “Measurement of Tumor Oximetry: a Comparison between Near-infrared Frequency-Domain Spectroscopy and 19F NMR Spectroscopy of Hexafluorobenzene,” Proc. SPIE-Int. Soc. Opt. Eng. 3597, 601-610 (1999).

95. Hanli Liu, R. R. Mapakshi, K. Lau, and C. L. Matson, “3-D Tumor Localization in Breast Phantoms,”16 th Annual Houston Conference on Biomedical Engineering Research , Univ. of Houston, Houston, TX, April 2-3, 1998.

96. Hanli Liu, M. Johns, and C. A. Giller, “Development of a Fiber Optic Reflectance Probe to Assist Neurosurgery,”16 th Annual Houston Conference on Biomedical Engineering Research , Univ. of Houston, Houston, TX, April 2-3, 1998.

97. Hanli Liu, Kelly Lau, and Charles L. Matson “Experimental Validation of an Algorithm for 3-Dimensional Tumor Localization in Turbid Media with a 2-Dimensional Frequency-Domain Measurement,” OSA Proc. on Advances in Optical Imaging and Photon Migration 21, 171-173 (1998).

98. Hanli Liu, Maureen Johns, and Cole A. Giller, “Investigation of Optical Reflectance from Human Brain in vivo for Guiding Brain Surgery,” OSA Proc. on Biomedical Optical Spectroscopy and Diagnostics/Therapeutic Laser Applications 22, 35-37 (1998).

99. Charles L. Matson and Hanli Liu, “Analysis of a 3-D tumor localization algorithm from a single 2-D measurement using diffraction tomography,” OSA Proc. on Advances in Optical Imaging and Photon Migration 21, 174-176 (1998).

100. Charles L. Matson and Hanli Liu, “The Fourier diffraction theorem for turbid media,” OSA Proc. on Advances in Optical Imaging and Photon Migration 21, 37-39 (1998).

101. Maureen Johns, Cole A. Giller, and Hanli Liu, “Guiding Pallidotomy Surgery by the Optical Reflectance of Human Brain Tissue,” 17 th Southern biomedical Engineering Conference, San Antonio, TX, Feb. 6-8, 1998.

102. S. Zhou, C. Xie, S. Nioka, H. Liu, Y. Zhang, and B. Chance, “Phased array instrumentation appropriate to high-precision detection and localization of breast tumor,” Proc. SPIE-Int. Soc. Opt. Eng. 2979, 98-106 (1997).

103. Hanli Liu and Britton Chance, “Quantitation of blood oxygenation in tissue: algorithms and error analysis” SPIE Biomedical Optics'97, San Jose, CA 8-14 February 1997.

104. Hanli Liu, David Boas, and Britton Chance, “Detectability of absorption changes in the brain by near infrared light,” SPIE European biomedical Optics'96, Vienna, Austria, Sept. 7-10, 1996.

105. Congwu Du, Hanli Liu, and Britton Chance, “Quantification of Hemoglobin Saturation on Tissue Phantom Using Phase-Modulation Spectroscopy”, Proc. SPIE-Int. Soc. Opt. Eng. 2925, 189-198 (1996).

106. Hanli Liu, David A. Boas, Arjun G. Yodh, and Britton Chance, “Influence of Clear Cerebrospinal Fluid on NIR Brain Imaging and Cerebral Oxygenation Monitoring,” OSA Proc. on Advances in Optical Imaging and Photon Migration 21 (1996).

107. Hanli Liu, Yutao Zhang, Mika Kimura, and Britton Chance, “Theoretical and Experimental Investigations on Solute-Induced Changes in Optical Properties in Living Tissues,” OSA Proc. on Biomedical Optical spectroscopy and Diagnostics 21 (1996).

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108. H. Liu, B. Beauvoit, and B. Chance, “Time-Resolved and -Unresolved Studies on Effects of Solutes on Tissue Optical Properties,” European Biomedical Optics ‘95, Barcelona, Spain, 12-16 Sept. 1995.

109. Hanli Liu and Britton Chance, “Quantitation of Blood Oxygenation in Muscles Using NIR Light,” International Society on Oxygen Transport to Tissue, Pittsburgh, August 23-27, 1995.

110. H. Liu, A. H. Hielscher, C. D. Kurth, S. L. Jacques, and B. Chance, “Time-Resolved Photon Migration in a Heterogeneous Tissue-Vessel Model,” Proc. SPIE-Int. Soc. Opt. Eng. 2389, 150-156 (1995).

111. H. Liu, D. A. Boas, Ed. Rachofsky, A. G. Yodh, and B. Chance, “A Simple Approach to Characterize Optical Properties and Blood Oxygenation in Tissue Using Continuous Near Infrared Light,” Proc. SPIE-Int. Soc. Opt. Eng. 2389, 496-502 (1995).

112. D. A. Boas, H. Liu, M. A. O'Leary, B. Chance, and A. G. Yodh, “Photon Migration within the P3 Approximation,” Proc. SPIE-Int. Soc. Opt. Eng. 2389, 240-247 (1995).

113. A. H. Hielscher, H. Liu, B. Chance, F. K. Tittel, and S. L. Jacques, “Frequency Resolved Reflectance Spectroscopy on Composite Tissue Structures,” Proc. SPIE-Int. Soc. Opt. Eng. 2389, 248-256 (1995).

114. T. Kitai, B. Beauvoit, H. Liu, and B. Chance, “Changes in the Light Path Length of Blood Perfused Rat Liver by Increased Hematocrit and Anoxia,” Proc. SPIE-Int. Soc. Opt. Eng. 2326, 326-333 (1994).

115. B. Beauvoit, T. Kitai, H. Liu, and B. Chance, “Time-Resolved Spectroscopy of Mitochondria, Cells, and Rat Tissues under Normal and Pathological Conditions,” Proc. SPIE-Int. Soc. Opt. Eng. 2326, 127-136 (1994).

116. H. Liu, D. Boas, B. Beauvoit, E. Rachofsky, and B. Chance, “Absorption and Scattering Properties in a Highly Absorbing Turbid Medium,” OSA Proc. on Advances in Optical Imaging and Photon Migration 21, 272-277 (1994).

117. H. Liu, A.H. Hielscher, B. Beauvoit, L. Wang, S.L. Jacques, F.K. Tittel, and B.Chance, “Determination of the Blood Oxygenation in the Brain by Time-Resolved Reflectance Spectroscopy (II): Contribution of Vascular Absorption and Tissue Background Absorption,” Proc. SPIE-Int. Soc. Opt. Eng. 2136, 15-25 (1994).

1 2 . CURRENT RESEARCH COLLABORATORS

Collaborators at UTSW (University of Texas Southwestern Medical Center at Dallas, TX): Between 1998-2005:

1. Ralph P. Mason, Professor, Department of Radiology, UTSW;2. Cole A. Giller, MD and PhD, (1998-2004) Neurosurgeon/Associate Professor, UTSW;

(2004-present) Medical Director of Radiosurgery Center at Baylor University Medical Center at Dallas.

3. Dwight German (2000-2004), Professor, Department of Psychiatry, UTSW.between 2005-present:

1. Edward Livingston, MD, Professor and Chairman, Department of General Surgery,

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UTSW;2. Jeff Cadeddu, MD, Associate Professor, Department of Urology, UTSW;3. Claus G. Roehrborn, MD, Professor and Chair, Department of Urology, UTSW;4. Richard Briggs, Professor and Director of Neuroimaging, UTSW;5. Mauricio Delgado, MD, Professor of Neurology, UTSW;6. Mario Romero-Ortega, Ph.D, Assistant Professor of Neurology, UTSW;7. Frank Andrew Kozel, MD, Assistant Professor of Psychiatry, UTSW;8. Mustafa Husain, MD, Professor of Professor of Psychiatry and Internal Medicine,

UTSW.

Collaborators at UT Arlington : 1. Khosrow Behbehani, Professor and Chairman, Dept. of BioEngineering, UT Arlington;2. George Alexandrakis, Assistant Professor, Bioengineering, UT Arlington;3. Boping Wang, Professor, Department of Mechanical Engineering, UT Arlington;4. Jianzhong Su, Professor, Department of Mathematics, UT Arlington;5. Yuan Bo Peng, Assistant Professor, Department of Psychology, UT Arlington;6. Hua Shen, Assistant Professor, Mathematics, UT Arlington.7. Liping Tang, Professor of Bioengineering, UT Arlington.8. Seoung Kim, Assistant Professor, Industrial Engineering, UT Arlington.

Collaborators at UNT Health Science Center at Fort Worth:1. James Simpkins, Professor and Chairman, Department of Pharmacology and

Neuroscience, UNTHSC at Fort Worth. TX.2. Anna Ratka, Associate Professor (2004-2006), Dept. of Pharmacology and Neuroscience,

UNTHSC at Fort Worth.3. Shaohua Yang, Assistant Professor, Department of Pharmacology and Neuroscience,

UNTHSC at Fort Worth. TX.4. Ignacy Gryczynski, Professor and Director, Microscopy Core Facility, Department of

Cell Biology and Genetics, UNTHSC.5. Zygmunt Gryczynski, Professor, Department of Molecular Biology and Immunology,

UNTHSC.

All the researchers and clinicians listed above have had either joint research grants (funded and pending) or are co-authors of scientific papers with Dr. Liu. Her link to both UTSW and UNT Health Science Center at Fort Worth enhances collaborative efforts between UT Arlington and the neighboring universities.

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HANLI LIU - University of Texas at Arlington · Web viewSept. 15, 2011invited for an invited...

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