Funding

Research Informing

Care

Thank you so very much for your encouragement and your kindness. Thank you for the time you gave to me on the phone. In allowing me to feel heard and understood, you have soothed my heart more than I can express. I deeply appreciate the support from the ABTA.

Providing and Pursuing Answers™

Founded in 1973, the American Brain Tumor Association (ABTA) was the first national nonprofit organization dedicated solely to brain tumor research. For nearly 40 years, the ABTA has been providing comprehensive resources that support the complex needs of brain tumor patients and caregivers, as well as the critical funding of research in the pursuit of break-throughs in brain tumor diagnosis, treatment and care.

FUNDING RESEARCH• Supportof:

› Early career scientists working to unravel the mysteries of brain tumors

› Projects that transition laboratory discoveries to actual patient treatment and care

› Discovery research

› Medical students participating in summer fellowships

› Neuro-oncology meetings, seminars and trainings

EDUCATION, INFORMATION AND SUPPORT • Publicationsandresourcesontumortypesandtreatments

• Supportivecarebyadedicatedteamoflicensed health care professionals

• UpdatesonbraintumorcareandtreatmentthroughtheABTA’s newsletter, educational webinars, monthly e-news and regular website postings at www.abta.org

• Nationalandregionalmeetingsforpatients,survivors, family members and caregivers

• TheonlineConnectionsSupportCommunity: www.abta.inspire.com

• MyCaringLink,theABTA’spersonalizedcaregivingsupporttool.Learnmoreatwww.abta.org.

• TrialConnect®,theABTA’sfreeclinicaltrialmatchingservice:www.abtatrialconnect.org

• Facebookpage:www.facebook.com/theABTA

• Twitterfeed:www.twitter.com/theABTA

One-on-OneSupportOur Care Consultants are available to assist patients in finding the answers they need, discussing options and helping them navigate the brain tumor journey.

CareLine: 800-886-ABTA (2282)

Email: abtacares@abta.org

Web: www.abta.org

FELLOWSHIPS

The American Brain Tumor Association Basic Research Fellowship is a two-year fellowship designed to encourage talented scientists early in their careers to enter, or remain in, the field of brain tumor research.

Christian Badr, PhDMassachusetts General Hospital, Charleston, MASponsor: Bakhos A. Tannous, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Susan Kramer

Priscilla K. Brastianos, MDDana-Farber Cancer Institute, Boston, MASponsor: William Hahn, MD, PhDAmerican Brain Tumor Association Basic Research Fellowship Supported by the Bradley Benton Davis Memorial Foundation

Myriam Chaumeil, PhD University of California San Francisco, San Francisco, CASponsor: Sabrina Ronen, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Team Survivor

Yi-Hsien Chen, PhDWashington University, St. Louis, MOSponsor: David H. Gutmann, MD, PhDAmerican Brain Tumor Association Basic Research Fellowship

Kevin Choe, MD, PhD University of Texas Southwestern Medical Center, Dallas, TXSponsor: Luis F. Parada, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Team Loving Life

Arthur Chou, MD, PhDDavid Geffen School of Medicine at University of California Los Angeles, Los Angeles, CASponsor: Linda M. Liau, MD, PhD American Brain Tumor Association Basic Research Fellowship Supported by Mr. & Mrs. William L. Jackson in Honor of Bruce Jackson

Jane Engler, PhDUniversity of California San Francisco, San Francisco, CASponsor: Joanna Phillips, MD, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Joel A. Gingras, Jr.

Vivian Gama, PhDUniversity of North Carolina at Chapel Hill, Chapel Hill, NCSponsor: Mohanish Desmukh, PhDAmerican Brain Tumor Association Basic Research Fellowship

David Infanger, PhDCornell University, Ithaca, NYSponsor: Claudia Fishbach-Teschl, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Team Will Power

Youngmi Kim, PhDCleveland Clinic Lerner Research Institute, Cleveland, OHSponsor: Jeremy N. Rich, MDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Jennifer Lynn Keith

Sichen Li, PhDUniversity of California Los Angeles, Los Angeles, CASponsor: Albert Lai, MD, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Naomi Berkowitz

Lori Mainwaring, PhDDana-Farber Cancer Institute, Boston, MASponsor: Keith Ligon, MD, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Joel A. Gingras, Jr.

Lisa Matlaf, PhDCalifornia Pacific Medical Center Research Institute, San Francisco, CASponsor: Charles S. Cobbs, MD, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Joel A. Gingras, Jr.

Braden C. McFarland, PhDUniversity of Alabama at Birmingham, Birmingham, ALSponsor: Etty (Tika) N. Benveniste, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Paul Fabbri

Chad Myskiw, PhDThe Salk Institute for Biological Studies, San Diego, CASponsor: Inder M. Verma, PhDAmerican Brain Tumor Association Basic Research Fellowship Supported by the GBM Research Fund

Ilwoo Park, PhDUniversity of California San Francisco, San Francisco, CASponsor: Sarah J. Nelson, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Theodore Sapper

Sujan Piya, PhDUniversity of Texas MD Anderson Cancer Center, Houston, TXSponsor: Juan Fueyo, MDAmerican Brain Tumor Association Basic Research Fellowship Supported by Stephen M. Coffman Charitable Trust

2012-2013 Research FundingThe American Brain Tumor Association Research Funding Program encourages career development in the field of brain tumor research, explores innovative research and seeks collaborative funding opportunities.

I believe that being recognized as an ABTA fellow led to more grant opportunities, support from my mentors and respect among my peers. It gave me confidence to continue doing the work I’ve been inspired to do.

Teodoro Pulvirenti, PhDSloan-Kettering Institute, New York, NYSponsors: Alan Hall, PhD and Eric C. Holland, MD, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Joan Ambriz

Maria Sambade, PhDUniversity of North Carolina at Chapel Hill, Chapel Hill, NCSponsors: Carey K. Anders, MD and C. Ryan Miller, MD, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Mark Linder

David Schonberg, PhDCleveland Clinic Lerner Research Institute, Cleveland, OHSponsor: Jeremy N. Rich, MD, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Joel A. Gingras, Jr.

Wendy See, PhDUniversity of California San Francisco, San Francisco, CASponsor: Russell Pieper, PhDAmerican Brain Tumor Association Basic Research Fellowship Supported by the Pray for Gray Foundation

An-Chi Tien, PhDUniversity of California San Francisco, San Francisco, CASponsor: David H. Rowitch, MD, PhDAmerican Brain Tumor Association Basic Research Fellowship

Leanne Wybenga-Groot, PhDHospital for Sick Children, Toronto, Ontario, Canada Sponsor: Jane McGlade, PhDAmerican Brain Tumor Association Basic Research Fellowship

Jian Zhang, PhDColumbia University New York, New York, NYSponsor: James L. Manley, PhDAmerican Brain Tumor Association Basic Research Fellowship in Honor of Denise Kimball

TRANSLATIONAL GRANTS

The American Brain Tumor Association Translational Grant is a one year award for pre-clinical research that critically evaluates the diagnostic and/or therapeutic potential of recent discoveries for advancement to clinical application.

Albert Lai, MD, PhDUniversity of California Los Angeles, Los Angeles, CA“Non-invasive Circulating Free DNA Methylation-based Biomarkers for Glioma Diagnosis and Surveillance”American Brain Tumor Association Translational Grant in Honor of Justin Porter

Ichiro Nakano, MD, PhDThe Ohio State University, Columbus, OH“CD44v as a Target in Therapy-Resistant Mesenchymal Glioblastoma”American Brain Tumor Association Translational Grant in Honor of Georgianne AuBuchon

G. Praveen Raju, MD, PhDWeill Medical College of Cornell University, New York, NY“Preclinical Assessment of Arsenic Trioxide and Resistance Mechanisms in a Novel Mouse Model of Sporadic Medulloblastoma”American Brain Tumor Association Translational Grant Supported by the Humor to Fight the Tumor Volunteer Event Committee

DISCOVERY GRANTS

The American Brain Tumor Association Discovery Grant is a one-year award supporting high-risk/ high-impact projects that have the potential to change current diagnostic or treatment paradigms for either adult or pediatric brain tumors.

Akemi Kosaka, PhDUniversity of Pittsburgh, Pittsburgh, PA“Immunological Soil in the Brain — Strategies for Prevention of Breast Cancer Metastasis”American Brain Tumor Association Discovery Grant

Michael Olin, PhDUniversity of Minnesota, Minneapolis, MN“Discovery of the Link Between Central Nervous System Tumors and Cervical Lymph Node Mediated Immune Suppression”American Brain Tumor Association Discovery Grant

Kai Tan, PhDUniversity of Iowa, Iowa City, IA“Multi-Analyte Network Markers for Brain Tumor Prognosis”American Brain Tumor Association Discovery Grant

Mingyao Ying, PhDHugo W. Moser Research Institute at Kennedy Krieger, Inc., Baltimore, MD“Hyaluronan-mediated Motility Receptor as a Novel Target for Inhibiting Glioblastoma Stem Cells”American Brain Tumor Association Discovery Grant

William C. Zamboni, PharmD, PhDUniversity of North Carolina at Chapel Hill, Chapel Hill, NC“Nanoparticle Agents for the Treatment of Metastatic and Central Nervous System Malignancies”American Brain Tumor Association Discovery Grant

RESEARCH The act of writing and being awarded the fellowship provided a wonderful confidence boost. Additionally, it provided me reassurance that the topic I am pursuing is considered important and valuable by some of the most respected brain tumor researchers in the world.

The impact that interacting with patients and seeing firsthand how our time in the lab can be translated to the patients

will be priceless. I was thankful the ABTA

provided us that opportunity. It will keep me motivated

for years to come.

MEDICAL STUDENT SUMMER FELLOWSHIPS

The American Brain Tumor Association Medical Student Summer Fellowship program is a three-month mentoring-focused summer program intended to motivate talented medical students to pursue a career in neuro-oncology research. Recipients of the 2012 summer awards are:

Student: Ranjith BabuSponsor: David Cory Adamson, MD, PhD, MHSc, MPHDuke University Medical Center, Durham, NCAmerican Brain Tumor Association Medical Student Summer Fellowship in Honor of Christopher Diez

Student: Cathleen Joyce ChangSponsor: Jeremy N. Rich, MDCleveland Clinic Lerner Research Institute, Cleveland, OHAmerican Brain Tumor Association Medical Student Summer Fellowship in Honor of PJ Lukac

Student: Melody ChungSponsor: Daphne Haas-Kogan, MDUniversity of California San Francisco, San Francisco, CAAmerican Brain Tumor Association Medical Student Summer Fellowship in Honor of Laura McDonnell

Student: Abdullah FerozeSponsor: Samuel H. Cheshier, MD, PhDStanford University School of Medicine, Stanford, CAAmerican Brain Tumor Association Medical Student Summer Fellowship

Student: Kartik KesavabhotlaSponsor: John A. Boockvar, MDWeill Medical College of Cornell University, New York, NYAmerican Brain Tumor Association Medical Student Summer Fellowship in Honor of Rose DiGangi

Student: Lisa M. KurtzSponsor: Sanjiv Sam Gambhir, MD, PhDStanford University School of Medicine, Stanford, CAAmerican Brain Tumor Association Medical Student Summer Fellowship in Honor of Jerilynne Beres

Student: Shadi LalezariSponsor: Albert Lai, MD, PhDDavid Geffen School of Medicine at University of California Los Angeles, Los Angeles, CAAmerican Brain Tumor Association Medical Student Summer Fellowship Supported by the Eric Perry Memorial 5k Run/Walk

Student: Benjamin LuSponsor: Dimitris Placantonakis, MD, PhDNew York University School of Medicine, New York, NYAmerican Brain Tumor Association Medical Student Summer Fellowship in Honor of Rose DiGangi

Student: Pete Pow-anpongkulSponsor: Balveen Kaur, PhDThe Ohio State University, Columbus, OHAmerican Brain Tumor Association Medical Student Summer Fellowship Supported by the Humor to Fight the Tumor Volunteer Event Committee

Student: Joel RabornSponsor: Gregory Friedman, MDUniversity of Alabama at Birmingham, Birmingham, ALAmerican Brain Tumor Association Medical Student Summer Fellowship Supported by the Chad Dunbar Bowling Tournament

Student: Wesley YuSponsor: Andrew Parsa, MD, PhDUniversity of California San Francisco, San Francisco, CAAmerican Brain Tumor Association Medical Student Summer Fellowship Supported by the Bill Heller Memorial 5k Run/Walk

BRAIN TUMOR FUNDERS’ COLLABORATIVE

The Brain Tumor Funders’ Collaborative is a partnership among the following private philanthropic and advocacy organizations: American Brain Tumor Association, Brain Tumour Foundation of Canada, Children’s Brain Tumor Foundation, James S. McDonnell Foundation, and the Sontag Foundation. Together, the Funders have supported three multi-million dollar projects, eleven biomarker feasibility studies and a workshop exploring the glioblastoma pre- and post-treatment milieu.

ABTA/AANS/CNS CLINICAL RESEARCH AWARD

A two year clinical award in collaboration between the American Brain Tumor Association, American Association of Neurological Surgeons, and the Congress of Neurological Surgeons. The grant supports clinical research trials designed to provide pilot project data for projects with direct clinical application.

Linda M. Liau, MD, PhDUniversity of California Los Angeles, Los Angeles, CA“Adoptive Transfer of NY-ESO-1 Genetically Engineered TCR for Treatment of Glioblastoma”

Applications for ABTA Basic Research Fellowships, Translational Grants andMedicalStudentSummerFellowshipsaredueJanuary 9, 2013. Visit www.abta.org for eligibility and applications.

RESEARCH

My fellowship provided valuable research funding to enable the conduct of these imaging studies in glioma models to generate valuable preliminary data that would pave the way for future studies.

As a young independent investigator, these funds from ABTA allowed my lab to better define research directions, participate in important collaborations, and recruit and cover expenses for our first graduate student. It has reaffirmed my commitment to cancer research.

INTERNATIONAL OUTREACH FELLOWSHIP

A collaboration between the American Brain Tumor Association, EMD Serono, and the Society for Neuro- Oncology, this one-year fellowship provides an opportunity for professionals from outside North America to perform clinical, translational or basic research in the area of pediatric or adult neuro-oncology in a clinical and/or laboratory setting in the United States or Canada.

Jun-Ping Zhang, MD Beijing Sanbo Brain HospitalMentor: Patrick Wen, MD, PhDHost institution: Dana Farber Cancer Institute, Boston, MA

BRAIN TUMOR EPIDEMIOLOGY CONSORTIUM (BTEC) JUNIOR INVESTIGATOR AWARDS

These awards support the research interests of early career epidemiologists by making it possible for them to present their work at the annual BTEC meeting amongst an international audience of epidemiologists.

Darryl NousomeUniversity of Texas, School of Public Health, Houston, TX

Anna Luisa Di Stefano, MDUniversity Pierre et Marie Curie, Paris, France

CENTRAL BRAIN TUMOR REGISTRY OF THE UNITED STATES (CBTRUS) GRANT

One of the primary objectives in ABTA’s founding, and continued support, of this registry is to ensure the existence of data on the incidence (the number of people diagnosed each year) and the prevalence (the number of people living with a brain tumor in any given year) of both benign and malignant brain tumors. World-renowned epidemiologists and neuro-pathologists now lead the domestic and international initiatives put forth by this registry. We nurture the CBTRUS initiative by providing support for the printing of this important data in recognition that this disease will be better understood once the true incidence of brain tumors is documented.

SPORE COLLABORATIVE FUNDING PROJECT

This initiative is the collaboration between the American Brain Tumor Association (ABTA), Accelerate Brain Cancer Cure (ABC²), the National Brain Tumor Society (NBTS) and the National Cancer Institute (NCI). Grants provided through this mechanism provide supplemental support to two clinical trials sponsored by NCI’s SPORE (Specialized Programs of Research Excellence) program.

Andrew Parsa, MD, PhDUniversity of California San Francisco, San Francisco, CA

John H. Sampson, MD, PhD, MHScDuke University Medical Center, Durham, NC

SURVIVORSHIP

These quality of life and symptom management studies are supported through a collaborative relationship with the Oncology Nursing Society. The funded research explores the impact of a brain tumor diagnosis on the lives of patients, families and survivors.

Thomas Hardie, EdD, RNDrexel University, Philadelphia, PAABTA/Oncology Nursing Foundation Neuro-oncology Nursing Small Grant“Latent Trajectories of Late Treatment Effects in Pediatric Brain Tumor Survivors”

Angela Starkweather, PhDVirginia Commonwealth University, Richmond, VAABTA/Oncology Nursing Foundation Neuro-oncology Nursing Small Grant “Glial Activation and Symptoms in Patients with Brain Tumor”

INDUSTRY SUPPORT

The ABTA provides collaborative funding to a pre-clinical study conducted by Tocagen Inc. for the evaluation of its investigational treatment “Toca 511 & Toca FC” in companion dogs with brain cancer.

I hope to continue to grow as a basic scientist

uncovering the metabolic underpinnings that drive glioblastoma cancer cells.

I sincerely thank ABTA for their support and

this experience.

RESEARCH

The American Brain Tumor Association is a trusted resource for brain tumor patients, caregivers and health care professionals around the country. From a wide range of publications to webinars and educational programs, our goal is to ensure that you have the tools and information you need. Visit our website at www.abta.org to see a full scope of all that we provide. Our complete line of patient education publications can be down-loaded from our website, and hard copies canberequestedbycallingourCareLineat800-886-ABTA (2282).

PUBLICATIONS · About Brain Tumors: A Primer

for Patients and Caregivers

Tumor Types· Ependymoma

· Glioblastoma and Malignant Astrocytoma

· Medulloblastoma

· Meningioma

· Metastatic Brain Tumors

· Oligodendroglioma and Oligoastrocytoma

· Pituitary Tumors

Treatments· Chemotherapy

· Clinical Trials

· Conventional Radiation Therapy

· Proton Therapy

·StereotacticRadiosurgery

·Steroids

·Surgery

RESOURCE SHEETS Coveringavarietyoftopics,including:· Care Options

· Bevacizumab and Temozolomide

· Employment Rights and Job Retraining Resources

· Cysts

·HairLoss

· Educating Children and Teenagers

Connections Online Community

The ABTA’s Connections online community, www.abta.inspire.com, links patients, families, friends, caregivers and health care professionals with each other for support and inspiration. Connections was created to provide a safe place to visit, join and interact with members of the brain tumor community nationally and around the world.

MyCaringLink

MyCaringLinkistheABTA’spersonalizedonlinetoolthatallowsyouto help others help you. Whether you are sending out a calendar of your needs (rides,meals,babysitting,etc.)orupdatingyourpersonalblog,MyCaringLinkallows you to communicate with family and friends at your convenience. Visit www.abta.orgtolearnmoreandsetupyourownMyCaringLinkpage.

TrialConnect®

TrialConnect®, the ABTA’s clinical trial matching service, is offered in both EnglishandSpanish.Visitwww.abtatrialconnect.org to find a clinical trial match based on your specific needs.

ConnectWithUs

A M E R I C A N B R A I N T U M O R A S S O C I AT I O N

Glioblastoma

and Malignant

Astrocytoma

A M E R I C A N B R A I N T U M O R A S S O C I AT I O N

Meningioma

A M E R I C A N B R A I N T U M O R A S S O C I AT I O N

Chemotherapy

A M E R I C A N B R A I N T U M O R A S S O C I AT I O N

For more information contact

an ABTA Care Consultant at:

CareLine: 800-886-ABTA (2282)

Email: abtacares@abta.org

Web: www.abta.org

8550 W. Bryn Mawr Avenue, Suite 550

Chicago, IL 60631