Efficacy and safety: check...by using the right sensor solution

Bram Stelt – Large Account ManagerBooth: 551

Cell: +31(0) 6 2117 7287bram@exergenglobal.comwww.exergenglobal.com

Requests from the market:

- Increased speed- Increased quality- Guaranteed safety

Downside: - Same or less budget- More challenging conditions

TRENDS

SOME EXAMPLES

Welding Flash Cure

The right sensor - simply not enough

- Innovative sensor technology- Smart mechanical engineering teams

and

- In depth know how of thermal processes

APPROACH

SENSORANICS METHODOLOGY

SENSOR BY DESIGN………………THE PROCESS

Velashape II

CASE STUDY – COSMETIC INDUSTRY

Potential Market for Fat Destruction Procedures

In a survey of 1,045 women in NA56% indicated interest in non-invasive fat destruction procedures

Total Addressable Market in the US: 19.5M Patients

World Market: $2 billion by 2017 ($700 million in the US - Globaldata)

MARKET SIZE

Survey Takeaway:• “Pain-free with no downtime, it’s effective and totally believable.”• “Over 75% of patients come in to my office and immediately ask “How much is it going to hurt?"

PAIN FREE TREATMENT - SAFETY

PRINCIPLE OF OPERATION

OBJECTIVE

Next generation, Velashape III:- Pain free treatments- More efficient treatment - No downtime.

Request- Non contact temperature sensor integrated in applicator for

skin temperature monitoring- Closed loop RF mechanism to ensure reaching the set-point

skin temperature for optimal treatment efficacy, and NOT exceed the set-point temperature for patient safety and comfort.

OBJECTIVE SYNERON

Our challenges:- Size – very limited space

available- Direct IR lamp interference- Field of view – lens- Ambient temperature

fluctuations- Gel applied on skin: thermal

gradient.

CHALLENGES

Solution: Sensor selection:- Small size- Thermocouple compatible- Unpowered- No drift- High accuracy- High repeatability- High interchangeability.

OUR CHALLENGE: SIZE – VERY LIMITED SPACE AVAILABLE

Direct influence from IR lamps: immediate sensor response when IR lamps were switched on – measurement error of approx 3C.

OUR CHALLENGE: DIRECT IR LAMP INTERFERENCE

Inner copper shroud blocking IR lamp radiation.

Inner surface of shroud must be very low emissivity, otherwise the temperature of the shroud itself is measured.

SOLUTION: DIRECT IR LAMP INTERFERENCE

OUR CHALLENGE: FIELD OF VIEW - LENS

SOLUTION: FIELD OF VIEW

SOLUTION: FIELD OF VIEW

No Power RequiredT/C Compatible

Compensates for the Ambient Temperature

AMBIENT TEMPERATURE COMPENSATION

ZnSe lens and window are not 100% transparent for IR radiation – some signal is absorbed:

Sensor spectral response: 5.5 – 20 µm

OUR CHALLENGE: BIG AMBIENT TEMPERATURE FLUCTUATIONS

The thermopile detector is responsive to the net power that it absorbs:P = σ * A * (Tt4 - Ta4)The Stefan-Boltzmann equation where:- P = net radiation power- A = surface area - Tt = target temperature - Ta = detector temperature.

Since the detector absorbs power at σ * A * (Tt4) and re-radiates power at its own temperature, the σ * A * (- Ta4) term is needed. Tt is attenuated by the additional lens and window attenuate Ta is unchanged: ambient compensation error

OUR CHALLENGE: BIG AMBIENT TEMPERATURE FLUCTUATIONS

1) Sensor thermally isolated: slower heat up and more uniform heating

2) Additional thermocouple to measure sensor housing temperature to allow accurate ambient temperature compensation1.

1: solution that is provided to Syneron is under NDA and can not be disclosed here. The example given here is more general in nature but covers the concept

SOLUTION: BIG AMBIENT TEMPERATURE FLUCTUATIONS

mVo

mVTC

SOLUTION: BIG AMBIENT TEMPERATURE FLUCTUATIONS

OUR CHALLENGE: GEL ON SKIN – THERMAL GRADIENT. SOLUTION: HEAT BALANCE

The results for Tt=24C and Tt=59C. - IRt/c = Initial temp. in degC,- t/c = additonal t/c temp in degC,- Corrected: with ambient temperature compensation - Scaled: with heat balance.

RESULTS

VelaShape III Advantages

Increased RF Power:

- End point temperature is achieved much faster- Reduction in treatment time- Consistent, reproducible resultst

Sophisticated Feedback Mechanisms:

- New closed loop RF mechanism and built in temperature sensor- Better monitoring for elevated temperature in the tissue- Increased patient comfort and safety

Movie

Two important items I would like you towalk away with:

1. Market is very demanding and keeps on challenging the industry

2. There is always a solution if the thermal process is thoroughly understood – sensor by design.

TO TAKE HOME

THANK YOU – TIME FOR ?Bram Stelt – Large accountmanager

Booth: 551

Cell: +31(0) 6 2117 7287bram@exergenglobal.comwww.exergenglobal.com

www.sensoranics.com