Faculty / Centre Updates - University of Cyberjayacyberjaya.edu.my › ... ›...

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International Conference AttendedName Date Conference Name Title of Paper/Presentation Venue

1 Mdm. Farah Azizah Omar

16-18 August 2016

9th Malaysia International Conference on Languages, Literatures and Cultures (Micollac)

The Relationship between Test Takers’ Critical Thinking Ability and their Performance on the Reading Section of Malaysian University English Test (MUET)

Rainbow Paradise Beach Resort, Tanjung Bungah Penang, Malaysia

Workshops/Seminars AttendedName Date Workshop/Seminar Name Title of Paper/Presentation Venue

1 AP Dr. Sharifah Fauziah Hanim Syed Zain

17 November 2016

Blended Learning Workshop

Asia Metropolitan University (AMU)

2 Mdm. Nurhafizah Shaharuddin

24 November 2016

Sesi Pengenalan Pelaksanaan Integrated Cummulative Grade Point Average (iCGPA) di Institusi Pengajian Tinggi Swasta

University Taylor’s Lakeside Campus

3 All CLGS Staff 23 November 2016

Seminar Towards Workplace Competence in Healthcare Profession

CUCMS Auditorium

Centre for Languages and General Studies (CLGS)

Participants for the Blended Learning Workshop

Faculty / Centre Updates

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It has been a busy year indeed for FOP members in terms of their participation in international or local conferences, attendance to various workshops and trainings organized internally or externally, sending their research students to conferences and also invited as speaker and facilitator to share their current development in the pharmaceutical sciences research field and expertise.

Research Conferences, Workshops and Trainings

Name Date Conference Name Title of Paper/Presentation Venue

1 Aslinda Jamil 23rd & 24th Jan 2016

Symposia Series on primary care medicines

LE MERIDIEN HOTEL, KL

2 Shaharuddin Abdul Rashid

30th Jan 2016 Training for Community Pharmacist- Analysis And Causality Assessment for Adverse Drug Reaction (ADR) Reports.

Wisma MPS Puchong

3 Suraiya Abdul Rahman

5-6 Feb 2016 Qualitative Data Analysis MPWS


30 March-2 April 2016

World Halal Conference 2016

KLCC


2-3rd April 2016

Research Proposal & Research Methodology.

Unisza International Campus, South City Plaza,

6 Assoc Prof Dr Wan Sazrina Wan Zaid

4th – 6th April 2016

8th World Conference on Educational Sciences

The Importance of Healthcare and Safety Issues & Criteria Affecting Parent’s Decision on Choosing Childcare Centre in Malaysia

University of Alcala, Madrid, Spain

7 Masro Mohamed, Dr Wan Rosalina Wan Rosli,Fauziah Zamri,Mahani Mahadi,Suraiya Abdul Rahman, Assoc Prof Dr Wan Sazrina Wan Zaid, Aslinda Jamil, Dr Yaman Walid Kassab

13-14th April 2016

Qualitative Research Workshop; Theory and Practice

CUCMS

8 Masro Mohamad

20th – 22nd April 2016

11th International Medical Education Conference (IMEC 2016)

Proficiency in using Malay layman’s terms among Pharmacy students in Klang Valley, Malaysia.

International Medical University

9 Fauziah Zamri 20th – 22nd April 2016

11th International Medical Education Conference (IMEC 2016)

Perception on PBL Skills among Pharmacy Alumni of CUCMS

International Medical University

10 Shaharuddin Abdul Rashid, Aslinda Jamil

22nd – 24th April 2016

Malaysian Diabetes Educators Society Scientific Conference

Connection @ Nexus Convention Center, Bangsar South, KL


30th April & 1st May 2016

Malaysian Tobacco Treatment Specialists (MATTS) Symposium at

Wisma MPS, Puchong

Faculty of Pharmacy (FOP)

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12 Rozila Ismail, Mahani Mahadi, Masro Mohamed, Dr Yaman Walid Kassab, Nurul Ashikin Jamludin, Aina Yazrin Ali Nasirudin

18-19th May 2016

Focus on Research Methodology

CUCMS

13 Nurul Ashikin Jamludin, Nurul Adilla Hayat Jamaluddin, Aslinda Jamil, Imtiaz K. Mohamed

24-25th May 2016

3rd National Wound Care Conference; From Science to Practice

CUCMS

14 Datin Mariani Ahmad Nizarudin

29 th May Seminar "Empowering Professionalism”

Holiday Villa, Subang

15 Assoc Prof Dr Shamima Abdul Rahman, Dr Rozila Ismail, Mahani Mahadi, Masro Mohamed, Dr Yaman Walid Kassab, , Aina Yazrin Ali Nasirudin, Nurul Ashikin Jamludin, Ahmad Rashidi Mohamad Tahir

15-16 June 2016

Focus on Scientific Writing CUCMS

16 Nurdiana Jamil 15-17th July 2016

16th Asian Conference on Clinical Pharmacy (ACCP), Seoul, South Korea

Difference of Performances of Cockroft-Gault and Modification of Diet in Renal Disease Equations in Estimating Kindey FUnction in Relation to Serum Creatinine and Albumin Levels

Seoul, Korea

17 Nurul Adilla Hayat @ Jamaluddin

15-17th July 2016

16th Asian Conference on Clinical Pharmacy (ACCP), Seoul, South Korea

The acceptance rates of pharmacist intervention methods in antibiotic prescribing in University Malaya Medical Center: a comparative study.

Seoul, Korea

18 Assoc Prof Dr Shamima Abdul Rahman, Masro Mohamad, Dr Wan Rosalina Wan Rosli

25-26th July 2016

Workshop on the workings of an IACUC

Grand Seasons Hotel, Kuala Lumpur

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19 Prof Dr Adnan, Assoc Prof Dr Shamima, Dr Wan Rosalina, Dr Mohd Ehsan, Dr Rozila Ismail, Mahani, Masro, Imtiaz K., Aina Yazrin, Shairyzah, Fauziah, Suraiya, Siti Nooruhani, Datin Mariani, Aslinda, Shaharuddin, Ismin, Waheedah

27-28th July 2016

FOP Publication Retreat Workshop (PRW)

Paya Indah Wetland

20 Assoc Prof Dr Shamima Abdul Rahman, Aina Yazrin Ali Nasirudin, Nurul Ashikin Jamludin, Fauziah Zamri, Siti Nooruhani Ibrahim, Dr Rozila Ismail

3-5th August 2016

Critical Appraisal and Research Supervision

CUCMS

21 Wan Hamidi Wan Sulaiman

8 – 9th Aug 2016

9th National Pharmacy R&D Conference

Hotel Everly Putrajaya

22 Dr Rozila Ismail 8th – 12nd August 2016

Minggu Penyelidikan Perubatan dan Kesihatan ke-18, Universiti Kebangsaan Malaysia 2016

Titanium dioxide coated with nanofiber facilitates the osteogenic potential of human adipose derived stem cells in a cocultured system

UKM

23 Assoc Prof Dr Shamima Abdul Rahman

15-16th August 2016, Putrajaya

30th Scientific Meeting of Malaysian Society of Pharmacology and Physiology (MSPP) 2016.

Effects of Erythroxylum cuneatum leaf alkaloid extract in carrageenan-induced inflammation in Sprague Dawley Rats.

IOI Hotel, Putrajaya

24 Wan Hamidi Wan Sulaiman

16-18th September 2016

International World Pharmacists’ Day 2016

MPS and MCPG Hotel Equatorial Penang

25 Mahani Mahadi 7th – 8th December 2016

25th Scientific Conference of the Microscopy Society Malaysia

Protective Effect of Kappaphycus alvarezii On The Heart Of Hypertensive and Hypercholesterolemic Induced Sprague-Dawley Rats.

Bangi-Putrajaya Hotel

26 Assoc Prof Dr Mohamed Awang

15th August 2016

2nd International Conference of Industrial Pharmacy ICIP 2016

Effect of neutron irradiation on the physicochemical properties of Naproxen Sodium

IIUM, Kuantan Pahang


21 & 22 Nov 2016

3rd International Halal Conference 2016,

Exploratory study on the halal status of nutritional and dietary supplements in two government hospitals within Klang Valley

Grand Bluewave Hotel, Shah Alam, Shah Alam

28 Datin Mariani Ahmad Nizarudin

21 & 22 Nov 2016

3rd International Halal Conference 2016,

Knowledge, attitudes and perception regarding the importance of halal status of prescription medications among patients in private hospital

Grand Bluewave Hotel, Shah Alam, Shah Alam

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Faculty also sent our research students to get exposed in conferences and participated as oral or poster presenter, and 1 of our student won best poster presenter under Pharmaceutical Sciences theme in PRC 2016. The participation list as stated below:

Student participation in conferences:

NoName of students

Type of participation/

Supervisor Title of Paper/Presentation

1 Frank Gibson Anak Peter

Oral presenter /PRC 2016

Ahmad Rashidi Mohamad Tahir

In-vitro study of effect of drug loading on drug release pattern of aripiprazole in-situ forming implant (ISFI) made of poly (lactide-co-glycolide)(PLGA) 50:50 in solvent NMP and DMSO

2 Nur Amirah Emira Abd Aziz


Waheedah Abdul Hakeem

Wound healing properties of Melicope ptelefolia extract on diabetic-induced mice

3 Rahimah Nur Iman Rohani


Assoc Prof Dr Wan Sazrina Wan Zaid

Development and validation instrument to measure knowledge and perception on substance abuse among public in Selangor

4 Nurul Izni Ahmad Zawawi

Poster presenter /PRC 2016

Prof Dr Rosnani Hashim

Evaluation of patients’ knowledge on atrial fibrillation and adherence to oral anticoagulant among atrial fibrillation patients in Hospital Putrajaya and Hospital Serdang.

5 Yap Kuang Jiet Poster presenter /PRC 2016

Prof Dr Rosnani Hashim

Drug-related problem in hospitalized patients with solid cancer

6 Chai Ka Yi Poster presenter /PRC 2016

Assoc Prof Dr Zainol Akbar Zainal

Knowledge and attitudes of public regarding HPV infection and vaccination in Kulaijaya, Johor

7 Lim Seow Li Poster presenter (* won best poster presenter) /PRC 2016

Assoc Prof Dr Shamima Abdul

Acute anti-inflammatory properties of Chinta mula leaves in rats

8 Aqilah Salim Poster presenter /PRC 2016


Antioxidant property and MTT assay screening of local and imported P. granatum

9 Syamilia Ramli Poster presenter /PRC 2016


Hepatoprotective effect of imported P. granatum on PCM induced-hepatotoxicity in rats.

10 Farah Hidayah Harmizi


Dr Yaman Walid Kassab

Quality of Life assessment on haemodialysis patient in Hospital Sultan Abdul Halim, Sungai Petani, Kedah

11 Nur Aliah Mustaffa Kamal


Dr Wan Rosalina Wan Rosli

Exploratory Study on the Potential Utility of HBA1C and Serum Lipid Level on Characterizing Patients with Coronary Artery Disease Managed in an Outpatient Facility in Selangor

12 Radhiah Azman Poster presenter /PRC 2016

Mahani Mahadi Effects of Kappaphycus alvarezii on Red Blood Cells of Hypertensive and Hypercholesterolemic Induced Rats.

13 Ahmad Lokman Al-Hakim


Mahani Mahadi The effects of Kappaphycus alvarezii on Sperm Damage of Hypertensive and Hypercholesterolemic Induced Rats.

14 Sia Te Vi Poster presenter /PRC 2016

Shairyzah Ahmad Hisham

Management of hypoglycaemia among hospitalised patients in Hospital Putrajaya

15 Diyana Aqilah Azhar


Nurdiana Jamil Knowledge, attitudes and perception among consumers in private hospitals towards the implementation of goods and services tax on medicines.

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16 Ain Izyan Shahirah Sokri


Ismin Izwani Zainol Abidin

The Prophylactic Effect of Nigella Sativa Oil Against Ovarian Cyst Leading to Polycystic Ovarian Syndrome and Infertility

17 Yap Chiou Hsien Poster presenter / PRC 2016

Ahmad Rashidi Tahir

In vitro study of effect of drug loading on drug release pattern of aripiprazole ISFI made of PLGA 75:25

18 Ooi Hong Yeong Poster presenter /PRC 2016

Nurul Adilla Hayat @ Jamaluddin

Knowledge and barriers on pneumococcal bacteria and pneumococcal vaccination in children among parents in primary care Putrajaya.

19 Siti Firas Ahmad Razef


Aslinda Jamil Perception on Quality of Life (QoL) among public university students and factors affecting it.

20 Anis Ismail Poster presenter /PRC 2016

Imtiaz K. Mohamed The effect of different concentrations of extracting solvent on the polyphenolic content and antioxidant activity of Gynura procumbens leaves.

21 Amylia Hanani Abdul Hamid


Suraiya Abdul Rahman

Descriptive analysis of trend and adoption rate of halal pharmaceutical standard.

22 Nabilah Zainuddin


Fauziah Zamri Development of Questionnaire: the role of packaging and labelling in the selection of cosmetic and skin care products among consumers in the outlets in Ayer Keroh, Melaka.

23 Nabilah Abdul Razak


Masro Mohamed A study on proficiency in translating English medical terminologies to Malay Layman’s terms using exam-based questionnaire amongst pharmacy students in Klang Valley, Malaysia.

24 Muhammad Faiz Abdul Halim


Datin Mariani Ahmad Nizarudin

Knowledge and perception of public towards adverse drug reaction reporting in Kedah

25 Nur Ammal Mohd Farit

Poster presenter /ACCP 2016


Factors affecting quality of life (QOL) in tuberculosis (TB) patients in Institut Perubatan Respiratori (IPR) in Kuala Lumpur.

26 Shuwirda Boon Seen

Poster presenter / ACCP 2016


Development and validation of HRQOL-TB (Malay version): a health-related quality of life (HRQOL) questionnaire for tuberculosis (TB) patient.

Appointment as SpeakersFaculty members have been invited in various events to share their research expertise as well as their professional expertise as a speakers.

No Name of speaker Event/Organizer Date Title of Slot

1 Suraiya Abdul Rahman Halal Development Cen-tre

19th January 2016 Awareness Workshop on Phar-maceutical.

2 Prof Dr Rosnani Hashim International Conference on Pharmacy Education & Practice (ICPEP) 2016, Bayview Beach Resort, Penang,

29-31 January 2016 Plenary Speaker “Bridging The Gap: Management Skill & Leadership”

3 Dr Wan Rosalina Wan Rosli International seminar in Pharmaceutical Technolo-gy, Sekolah Tinggi Farmasi Bandung

26th – 29th January 2016

Pharmacogenomics: Usher-ing the era of personalized medicine.

4 Dr Izyan Abdul Wahab Bahagian Perkhidmatan Farmasi, Jabatan Kesiha-tan Negeri, Negeri Sem-bilan

16th May 2016 Workshop on Scientific Writing


Kelantan LPKIM 21st May 2016 Health Talk and Medical Check Up

6 Nurul Adilla Hayat @ Ja-maluddinNurdiana Jamil

KPJ University College 24th May 2016 Polypharmacy & Usage Opti-misation in Diabetes

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7 Prof Dr Rosnani Hashim Dewan Serai Wangi, Phar-macy Division, MOH

25th May 2016 Speaker “Hands On Log Book Components, R & D Based University”

8 Assoc Prof Dr Shamima Abdul Rahman

3rd Pharmaceutical Research Conference for Pharmacy students and Young Graduate

27th May 2016 Pre-conference Workshop: Ro-dent Handling Workshop


3rd Pharmaceutical Research Conference for Pharmacy students and Young Graduate

27th May 2016 Pre-conference Workshop: Questionnaire development

10 Dr Yaman Walid KassabAina Yazrin Ali Nasirudin

KPJ University College 19th July 2016 Polypharmacy CPD Series: Renal Disorders


CUCMS 5th August 2016 Research enhancement work-shop - critical appraisal and research supervision. Title: Su-pervising Questionnaire Based Research.

12 Assoc Prof Dr Zainol Akbar ZainalDr Izyan Abdul Wahab

KPJ University College 16 August 2016 Geriatric Care

13 Dr Mohammad EhsanShairyzah Ahmad Hisham

KPJ University College 21 Sept 2016 Polypharmacy & usage opti-misation in Cardiovaascular Diseases

14 Suraiya Abdul Rahman CUCMS 24th September 2016

Pocket Talk on Halal Industry

15 Ahmad Rashidi TahirAslinda JamilDr Mohd Ehsan Zulfazley Abdul Rahman

KPJ University College 11th October 2016 Polypharmacy CPD Series: Respiratory Disorders”

16 Dr Mohd Ehsan Zulfazley Abdul RahmanNurul Ashikin Jamludin

KPJ University College 25th October 2016 Polypharmacy CPD Series: Hypertension

17 Dr Izyan Abdul Wahab Bahagian Perkhidmatan Farmasi, Jabatan Kesiha-tan Negeri, Negeri Sem-bilan

19th November 2016 Adverse Drug Reaction and Reporting: When and How?”

Awards

Name Award Title

Assoc Prof Dr Shamima Abdul Rah-man

IIDEX 2016Research Institute Business Unit,

UiTM (Gold Award)Piper Derma cream


Apprentice Innovation Research Exhi-bition (AIREx 2016)

(Gold Award)Piper Wound Care


International Invention & Innovative Competition (InIIC Series 2/2016)

PIPER-Aid Cream


Citra Ilmu Award 2016(Excellent Research Award)

Dr Rozila Ismail

Minggu Penyelidikan Perubatan dan Kesihatan ke-18, Universiti Kebang-

saan Malaysia 2016(Best Poster Award)

Titanium dioxide coated with nanofib-er facilitates the osteogenic potential of human adipose derived stem cells

in a cocultured system

Ismin Izwani Zainol AbidinClute Institute

(Best Research Award)To write or not to write

Prepared by: Assoc. Prof. Dr. Shamima Abdul Rahman

Head of Publication, Research, Entrepreneurship and Institutional Networking Unit (P.E.R.I.N.D.U), Faculty of Pharmacy.

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Crème de la crème:The Impact of Pharmacist-Initiated Interventions

in Improving Acute Coronary Syndrome Secondary Prevention Pharmacotherapy Prescribing upon Discharge

Published in Journal of Clinical Pharmacy and TherapeuticsImpact Factor: 1.833ISI Journal Citation Reports© Ranking: 2015: 163/255 (Pharmacology & Pharmacy)Online ISSN: 1365-2710Blackwell Publishing Ltd

Dr. Yaman Walid Kassab, Prof. Yahaya. Hassan, Prof. Noorizan. Abd Aziz, Dr. Hadeer Akram and Dr. Omar Ismail

Abstract

Background: Pharmacists have the knowledge regarding optimal use of medications and the ability to influence physician prescribing. Successful interventions by a pharmacist to implement cardioprotective medications to a coronary artery disease patient’s regimen would not only improve the patient’s quality of care but may also increase his or her likelihood of survival.

Objectives: In this study, we aimed to (i) evaluate the effectiveness of pharmacist initiated interventions in increasing the prescription rates of ACS secondary prevention pharmacotherapy at discharge, and to (ii) evaluate the acceptance rate of these interventions by prescribers.

Methodology: This was a comparative study with a pre-intervention and post intervention design. In the pre-intervention phase, a retrospective cross-sectional audit was performed. Patients with a diagnosis of acute coronary syndrome admitted to the hospital in the period from 2008 to January 2010 were identified from medical records and served as a historical control. The second phase (intervention phase) was conducted from the beginning of March to the end of September 2010.Two random samples of 190 patients with ACS were included. During the intervention phase, two hospital pharmacists made rounds with the cardiology team and gave secondary prevention recommendations when needed. The major reference for the recommendations was the Malaysian guidelines.

Results: A total of 72 interventions were made by pharmacists. of which drug initiation was most common (59.7%) followed by recommendations to change to another medication (23.6%) and optimization of medication dosing (16.6%). Most recommendations (72.2%) were accepted by prescribers. Majority of accepted recommendations were with ß-blockers (38.46%) followed by those with ACE inhibitors (28.8%). The intervention had a significant impact on the utilization rates of ß-blockers (increased from 75.8% to 84.7%, p = 0.028), ACEI/ARBs (from 65.3% to 74.7%, p = 0.044) and statins (from 91.6% to 98.4%, p = 0.002). The intervention had also led to a significant increase in the utilization rates of all these 4 classes together (from 42.6% to 62.6%, p = 0.001).

Conclusion: A pharmacist on cardiology units increased the use of beta-blockers, aspirin, and statins for the secondary prophylaxis of ACS.

Keywords: Drug Utilization, Pharmacist-initiated interventions, Secondary prevention, Acute coronary syndrome

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Table 1. Types of Recommendations provided by the pharmacists

Intervention No. (%) interventions

Drug initiation

ß-blocker 19 (26.4)

ACEI 16 (22.2)

Statin 4 (5.6)

Aspirin 4 (5.6)

Change to another medication

Change ACE-I with ARB 8 (11.1)

Change to another Statin 6 (8.3)

Change Aspirin with Ticlid 3 (4.2)

Optimize dosing

Optimize the dose of ß-blocker 7 (9.7)

Optimize the dose of Statin 5 (6.9)

Table 2.Proportion of patients discharged on a regimen of secondary prevention medications

Drug class Control group n (%)

Intervention groupn (%) p value*

Aspirin 175 (92.1) 182 (95.8) 0.132

Aspirin + Clopidogrel 153 (80.5) 157 (82.6) 0.597

ACE-Inhibitor/ ARB 124 (65.3) 142 (74.7) 0.044

Beta-blocker 144 (75.8) 160 (84.2) 0.040

Statins 174 (91.6) 187 (98.4) 0.002

Combined EBM 81 (42.6) 119 (62.6) < 0.001

Bold means that there is a statistically significant difference (p value < 0.05) *Chi-square test

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Discovery Of Bioactive Secondary Metabolites From The Leaves Of Vitex Pinnata And Metabolomics Of

Its Endophytic Fungus, Nigrospora SpN Kamal, C Clements, AI Gray, R Edrada-Ebel

Published as:N Kamal, C Clements, AI Gray , R Edrada-Ebel (2011) Discovery of bioactive metabolites from the leaves of Vitex pinnata using high-throughput flash chromatography. Planta Medica, 77 (12). p. 1348.

AbstractBackgroundThere is a paucity study reported on bioactive metabolites from Vitex pinnata and to our best knowledge there is none from its endophytic fungi. In Malaysia, leaves of V. pinnata were traditionally used to treat cuts and wounds while the bark decoction is used for stomach ache and post-childbirth medicine. This study aims to isolate and identify the secondary metabolites from V. pinnata and to use metabolomics approach in the fungal natural products derived from V. pinnata.

MethodsThe ground leaves of V. pinnata (1 kg) were extracted in a Soxhlet apparatus at 40°C by utilising three different solvents based on their polarity. Later the extracts were concentrated in vacuo by using rotary evaporator at 40ºC and the yield was 6.33g (n-hexane extract), 6.5g (ethyl acetate extract) and 5.2g (methanol extract). Fractionation of the n-hexane extract (6.33g) was accomplished by using Medium Pressure Liquid Chromatography (MPLC). Metabolomic profiles of Nigrospora sp, a fungus derived from V. pinnata were established by submitting the extracts for Liquid Chromatography Mass Spectrometry (LC-MS) and the data was analysed and compared with available databases.

ResultSeven compounds were isolated by employing high throughput flash chromatography which proved to be reproducible, efficient and robust. New terpene was isolated for the first time together with six known compounds. Based on HRMS and 1D and 2D NMR, the new terpene was identified as. Apigenin 5,7 dimetyl ether, retusin and β-sitosterol showed strong antiinflammatory activity in NFĸB inhibition assay while only retusin and β-sitosterol were active against Mycobacterium marinum. New terpene and pheophorbide a bleached the DPPH (0.2% in MeOH) purple colour indicating antioxidant activity. Metabolomic profiles of all isolated endophytic fungi were done and Nigrospora sp (P4), which exhibited bioactivities was selected for further investigation. Tools of metabolomics were applied to optimise the production of bioactive secondary metabolites and develop the cultivation processes for large scale fermentation. Metabolomics proved to be powerful and selective tool in mining promising bioactive compounds from Nigrospora sp isolated from V. pinnata. Consequently, this plant is a promising source for bioactive metabolites and perhaps novel compounds from its endophytic fungus, Nigrospora sp.

ConclusionVitex pinnata produced various types of compounds mainly flavonoids, steroids and new terpenes with interesting bioactivities. Metabolomics of endophytic fungus, Nigrospora sp isolated from V. pinnata revealed it selectivity in bioactivities in different days and media. Also the cultivation process for upscale were able to optimised by using tools of metabolomics

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Reshma Mohamed AnsariPublished in Indian Journal of Pharmacology 2016; 48:338-9.

Currently, the medical fraternity is facing a challenge in treating dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) apart from classical dengue fever (DF).[1] The pathophysiological mechanism by which the virus induces thrombocytopenia is bone marrow suppression due to circulating interleukins as a result of stringent host immune response.[2] The dengue virus is trophic toward the cells of the monocyte macrophage system and endothelium, inducing apoptosis to a larger extent and necrosis to a lesser extent.[2] As a result, the virus infects the vascular endothelium inducing a spontaneous aggregation of platelets to them, culminating in peripheral platelet lysis.[3,4] The interleukins tumor necrosis factor-C, interleukin-1d, interferon alpha, soluble CD4, soluble CD8, interleukin 2, and interferon gamma A also disrupt the zona adherens of the endothelial cells, causing them to retract and open the intercellular junction, thus increasing vascular permeability.[4] Although platelets play a vital role in maintaining the intercellular junctions of endothelium, thrombocytopenia in DHF offers no help to the already fragile vascular wall.[2] In the peripheral circulation, premature destruction of platelets is induced by abnormal activation and prevention of normal platelet aggregation and direct infection of the platelets by the virus.[4] Auto immune-mediated destruction of platelets and an interesting concept of immune deviation manifested by immature atypical neutrophil, lymphocyte population, over production of interleukins and deranged T-cell response has been noticed by researchers.[3,4] The NS1 antigen expressed on the surface of the infected cell mediates complement activation which may also be involved in vascular leakage in DHF/DSS patients.[4]

Oral consumption of Carica papaya L. extract leaves is found to increase the platelet levels as early as 24 h with a significant increase in the total white blood cell and neutrophil counts as well.[5] In murine models, the extract combats heat and hypotonicity-induced hemolysis of cells by exhibiting its membrane stabilizing properties in erythrocytes and lysosomes thereby inhibiting the release of proteolytic enzymes.[4] As a sequel, Subenthiran et al. confirmed the lowering of hematocrit levels in dengue patients after administration of the extract.[5] As known earlier, arachidonate 12-lipoxygenase (ALOX 12) also known as the platelet type lipoxygenase (ALOX 12) gene aids in the production and differentiation of megakaryocytes which leads to the production of 12-hydroxyeicosatetraenoic acid and therein production of platelets. Adding on, platelet-activating factor receptor (PTAFR) gene, expressed in megakaryocytes is involved in platelet aggregation.[5] The RNA extracted from the blood of the patients who were administered the extract showed a 15-fold increase in the ALOX 12 gene activity. This gene is platelet-specific and is a direct target of transcription factor RUNX1 in megakaryocytes and platelets.[5] As reported, there was a 13.42-fold increased expression of the PTAFR gene among the patients who were given the extract orally as compared to the control group substantiating the role of papaya extract in platelet aggregation.[5] It has been noted that two components of a viral serine protease, NS2B and NS3, play a pivotal role in viral replication. It is crucial for the production of the polyprotein precursor before the assembly of the viral complex.[6] Researchers screened the flavonoid components of papaya leaves and concluded that quercetin has significant inhibitory activity against NS2B-NS3 serine protease, particularly against Dengue virus serotype 2 and exerts its antiviral property by preventing viral assembly.[6]

The major hurdle in using these leaves for treatment, is the dearth of substantial and consistent findings. Concrete evidence is still lacking as significant number of studies were done on patients solely based on the symptoms alone.[4] As on date, a study in Malaysia and a pilot study in Bengaluru, India were found to have a systematic approach in evaluating the effect of the leaf extract.[1,4] Although capsules of the extract are currently marketed in India[1] the mode of preparation, pharmacokinetic properties and the absorption of the active ingredient are still grey areas to be addressed.[4] Hopefully in future, this can be meted out by conducting large-scale studies in DF confirmed human subjects in a tertiary hospital set up, standardizing the dosage and period of the intervention.

References1. Gowda AC, Vijay Kumar NB, Kasture PN, Nagabhushan KH. A pilot study to evaluate the effectiveness of Carica papaya Leaf

extract in increasing the platelet count in cases of dengue with thrombocytopaenia. Indian Med Gaz 2015; 149:109-16.2. Martina BE, Koraka P, Osterhaus AD. Dengue virus pathogenesis: An integrated view. Clin Microbiol Rev 2009;22:564-81.3. Swati P, Supritha S, Rama B, Shridhar N. Evaluation of platelet augmentation activity of Carica papaya Leaf aqueous extract in

rats. J Pharmacogn Phytochem 2013;1:57-60.4. Sarala N, Paknikar S. Papaya extract to treat dengue: A novel therapeutic option? Ann Med Health Sci Res 2014;4:320-4.5. Subenthiran S, Choon TC, Cheong KC, Thayan R, Teck MB, Muniandy PK, et al. Carica papaya leaves juice significantly accelerates

the rate of increase in platelet count among patients with dengue fever and dengue haemorrhagic fever. EvidBased Complement Alternat Med 2013;2013:616737.

6. Senthilvel P, Lavanya P, Kumar KM, Swetha R, Anitha P, Bag S, et al. Flavonoid from Carica papaya inhibits NS2B-NS3 protease and prevents dengue 2 viral assembly. Bioinformation 2013;9:889-95.

Extract of Carica papaya L. leaves: Standardising its use in dengue fever

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Lab ProfileMolecular Research LabA PCR machine (also known as a thermal cycler), electrophoresis set and gel documentation system are basic equipment needed in molecular study. This equipment is available in the Molecular Research Lab, Level 2, CUCMS.

PCR machine

Electrophoresis set

Gel documentation system

History of PCRPCR was developed in the 1980s by Kary Mullis, who won a Nobel Prize in 1993 for the invention. From then on, PCR has been widely used as a diagnostic and research tool. The discovery of PCR brought enormous benefits and has widespread use over many scientific disciplines such as molecular biology, microbiology, genetics, clinical diagnostics, forensic science, hereditary studies and paternity testing.

What is PCR?PCR or Polymerase Chain Reaction is a technique used to make multiple copies or to amplify a single copy of a segment of DNA of interest, generating a large amount of copies of a particular DNA sequence. PCR can be performed by using DNA source from a variety

of tissues and organisms. Only minute amounts of DNA are needed for PCR to generate enough copies of DNA to be analyzed in just a few hours. The copied DNA then can be used in a wide variety of research.

Sources of DNADNA can be extracted from various sources such as:• Blood• Saliva• Semen• Hairroots• Skincells• Softtissues-buccalswabs• Microbes

PCR and Genetic TestingPCR can be used in genetic testing to reveal mutations which are responsible for hereditary disease. Prospective parents can be helped by knowing whether their children will be at risk from developing certain diseases. By using PCR, prospective parents can be tested for being genetic carriers or their children who might be affected by a disease. With PCR, diseases can be diagnosed even before birth. Prenatal testing can be done by obtaining DNA samples from amniotic fluid or chorionic villus (placenta tissue).

Cancers are caused by a series of mutations. PCR can be used to characterize mutations associated with carcinogenesis. PCR may be used to look for changes in genes which relate to cancer such as BRCA1 and BRCA2 genes that relate to breast, ovarian and pancreatic cancer. Mutation of either one of these genes will increases the risk for cancer.

By Dr Intan Zarina Zainol Abidin, CGSRC

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PCR and Paternity TestingPCR can be used to determine maternity, paternity and other blood relationships of individuals based on their genetic profile. Similar genes scattered throughout different species or populations can also be analyzed in order to determine the evolutionary distance of related species.

Paternity testing starts with extracting DNA from buccal swab or blood samples. PCR will amplify the limited amount of extracted DNA and generate enough copies for a genetic profile. Determination of biological relationship can be done by looking for a match between all profiles of tested parties.

PCR and Infectious Disease PCR can be used in the diagnosis of infectious disease caused by fungi, bacteria and viruses, so that treatment can be started earlier. PCR can be used to screen infections of donated blood such as tuberculosis which are difficult to culture in the laboratory. Besides, PCR can also be used to detect gonorrhea and chlamydia in urine samples. Detection of human immunodeficiency virus or HIV from blood samples can also be done using PCR.

PCR and Tissue TypingPCR can also be used as a test for tissue typing prior to transplantation of tissues or organs to determine the type of histocompatibility antigens on a person’s cells or tissues. This is to ensure as close a match as possible between the donor and the recipient. The presence and absence of antigens can be detected using PCR by determining the presence of the gene for the antigens in the cells.

PCR and Drug DiscoveryPCR is a potential tool in testing new possible drugs. Since toxicity is a major concern in every new drug, PCR can be used to observe how cells respond to these new compounds. Changes of gene expression during the process or treatment can be analyzed. Example of research:Determination of expression of specific molecular markers during certain biological process (e.g. differentiation process) is one of the research methodology that can be done by using PCR. Activation or inactivation of genes can be analyzed at different stages of a biological process.

Source: Cell Communication and Signaling 2010, 8:29.

Molecular Analytical Research LabLevel 2, CUCMS

38

Mr Azhar Tajul Noor is the Manager at the Cyberjaya University College of Medical Sciences (CUCMS) Library. Let’s take this rare opportunity to know

more about Mr Azhar

Firstly, can you share a bit about yourself?My undergraduate education was at Mara Institute of Technology (ITM, Shah Alam), in Library Science during the 1990s; and I got my first job as Automation Librarian at Universiti Tun Abdul Razak (UNITAR) Library in 1999. I then went to the University of Malaya in Kuala Lumpur where

I completed my Masters in Information Technology. I’m actively involved in the national and international library committee. My research interests include

the work on Semantic Web, Data Mining, Information Management, Knowledge Management and Information Systems.

Can you describe your day to day work tasks?Generally, the main task as the library manager is to oversee and manage the organization and operation of the University Library, supervise and train all library staff and assist users in the use of materials, equipment, and/or services provided by the library. To add, as a library manager, strong communication and organizational skills, knowledge of financial budgeting practices, and the ability to direct others is a must, in addition to having standard knowledge of library services, resources, and tools.

If you have a chance to share your advice to CUCMS researchers regarding usage of library facilities, what would it be?Google is not the answer to everything. Thus, fully utilizing the library services and facilities is essential in ensuring research is of a good quality in terms of content. To do this successfully, the library needs to intimately understand the needs and behaviour of the user and the point of interactions with the library service.

The library has demonstrated the ability to lead and to adapt roles in response to changing circumstances. It plays a crucial role in supporting the teaching, learning and research missions of the university.

It is important for libraries to share ideas and experiences, and to test what works and what does not. But we believe it is crucial for libraries to exploit the potential for co-operation in developing a range of shared services in order to enhance efficiency, as well as the scope and quality of what to provide to the end user.

What is the librarian’s role in the educational system?A librarian has an integral part in the educational system. The librarian is a resource provider for lecturers, students and the whole university community. For instance, lecturers and librarians can jointly plan programs that help increase the students’ information and knowledge base.

How can the librarian and lecturer work together to enhance students’ education?A librarian and a lecturer can prepare special programs from the resources they have to enhance the educational experience of the student. The lecturer will generally have the goal and method of presenting the lesson; the librarian can supply the sources and location of information, and how to obtain it in usable form.

If we ever need to contact you, how should we do that?You may reach me via email at [email protected] or office telephone at (6)03 – 83137000 (ext. 7224)

focusPersonalityMr Azhar Tajul Noor

39

TURNITINTurnitin is the leading originality checking and plagiarism prevention service used by millions of students and faculty, and thousands of institutions worldwide. Turnitin encourages best practice for using and citing other people’s written material. The service offers a complete web-based service to manage the process of submitting and tracking papers electronically, providing better and faster feedback to students.

Originality CheckThe Originality Report is the result of comparison between the

text of the submission against the search targets selected for the assignment which may include billions of pages of active and archived internet information, a repository of works previously submitted to Turnitin, and a repository of tens of thousands of periodicals, journals, & publications. Any matching or highly similar text discovered is detailed in the Originality Report that is available in the assignment inbox. Originality Reports provide a summary of matching or highly similar text found in a submitted paper.

Turnitin User Guides and Manuals◊ Turnitin has a web page available for user to access Guides and User Manuals at http://guides.turnitin.com/◊ If you access Turnitin directly via the Turnitin.com websites, please click on the “Manuals and Guides” link

to access the relevant guides. ◊ If you access Turnitin via an integration (such as Blackboard, Moodle, or Angel) please click on the

“Integrations” link and select the integration used by your institution to access the relevant guides.

Thesis RoomThe Cyberjaya University College of Medical Sciences (CUCMS) Library’s thesis room holds archival copies of all Masters and Bachelor theses completed at the University. There is one thesis room that may be used to refer to theses submitted by students to the CUCMS Library. This room is open for booking during the library’s opening hours by filling up a Room Reservation Form that is available at the Circulation Counter.

This theses collection consists of almost 200 titles which cover subjects on medicine, pharmacy and occupational safety and health. The complete list of the titles can be traced by user in a file located in this room. The hard copy theses are not available for loan. Instead, they can be read in this room only. Researchers are permitted to undertake self-copying of material, according to the Copyright Act 1987.

All theses are classified using the national standard of classification scheme which is the Library of Congress Classification (LCC) System.

CUCMS Library - Thesis Room

#Library

LibraryServices

Turnitin

LibraryFacility

Thesis Room

40

Nanoparticles of hydrophobised polysaccharides for drug delivery applications

IntroductionNanotechnology is one of several promising current approaches in developing efficientsystems for intracellular delivery of therapeutic agents that can range from small moleculedrugs to biomacromolecules. One of the critical problems in delivering drug intracellularly isrelated to the protective role of cell membranes that allow only small molecules with high lipidsolubility to pass through. Biocompatibility and ease of chemical modification are attractiveproperties of polymeric nanoparticles and make them suitable for this approach [1]. Thederivatization of polymers with alkylglycerols can increase their hydrophobicity, thus aidingwith the particle penetration across the membrane [2].The aim of this study is to modify biocompatible and biodegradable polysaccharides such asguar gum and pectin (that also have good drug carrier properties and offer functional groupsfor ease of modification) with alkylglycerols and to use these materials for the formulation ofnanocarriers that will be further tested for their suitability in drug delivery applications.

Materials and Methods▪ Guar gum (GG), low esterified pectin (pectin), butyl glycidyl ether (BGE), glutaraldehyde

(GTA), glycerol (stabilizer), span 80, dichloromethane (DCM) are the materials that havebeen used in this study.

▪ To modify the polysaccharides, GG and pectin were treated with BGE in alkalineenvironment at 45oC to yield butylglyceryl derivatives. The resulting products were purifiedby dialysis and characterized by NMR and FT-IR spectroscopic methods. The degree ofsubstitution has been calculated from 1H-NMR spectra.

▪ To formulate the nanoparticles, in-situ polymer crosslinking with GTA was performed in oilin water emulsion (procedure represented below). The diameter of particles wasdetermined by Dynamic Light Scattering (DLS) and Nanoparticulate Tracking Analysis(NTA), and the zeta potential was determined by electrophoretic measurement using aMalvern Zetasizer.

Conclusions

Fig. 2. Preparation and characterization of BGE-modified guar gum : a) Reactionscheme; b) 1H-NMR spectrum (example)

Mohammad F B Bostanudin, Darek Gorecki, Eugen Barbu

0.5% modified

GG (water phase)

2% Span 80 in DCM (oil phase)

emulsion

Stir vigorously

Mix understirring

Glycerol (stabilizer)

25% GTA solution (cross-linker)

Nano-particles

Mix under stirring

Mix under stirring Centrifugation

Fig. 1. Example of FT-IR spectra of non modified guar gum (top) and BGE-modified guargum (bottom)

Table 1. Characteristics of BGE-modified guar gum nanoparticles. (n=3, ± S.D)

0

5

10

15

20

25

30

1.0 : 41.0 1.0 : 52.0 1.0 : 63.0

Deg

ree

of s

ubst

itutio

n (%

)

GG : BGE molar ratio

0

0.5

1

1.5

2

2.5

3

3.5

1.0 : 68.0 1.0 : 108.0

Deg

ree

of s

ubst

itutio

n (%

)

Pectin : BGE molar ratio

Fig. 3. Equations and degree of substitution of : a) guar gum; b) pectin, with BGEusing different ratios. (n=3, ± S.D.)

▪ Pectin and guar gum have been successfully modified with BGE using different ratiosaccording to the chemical reaction described in Fig. 2.

▪ The modifications have been confirmed by 1H- and 13C-NMR and FT-IR spectroscopicmeasurements (examples given in Fig. 1 and Fig. 2).

▪ The degree of substitution has been calculated from 1H-NMR spectra by using theequations in Fig. 3; values in the range 15-23% for guar gum and 1.5-3% for pectin wereobtained.

Results and Discussions

[1]. Nam HY, Kwon SM, Chung H, Lee S-Y, Kwon S-H, Jeon H, et al. Cellularuptake mechanism and intracellular fate of hydrophobically modified glycolchitosan nanoparticles. Journal of Controlled Release. 2009;135(3):259-67.[2]. Lien CF, Molnár E, Toman P, Tsibouklis J, Pilkington GJ, Górecki DC, et al. Invitro assessment of alkylglyceryl-functionalized chitosan nanoparticles aspermeating vectors for the blood-brain barrier. Biomacromolecules.2012;13(4):1067-73.

Guar gum and pectin have been successfully modified with butyl glycidyl ether,with modified guar gum showing higher degree of substitution within the 15-23%range compared to pectin with only 1.5-3% degree of substitution.

Nanoparticles formulated from BGE-modified guar gum were in the size range of100-250 nm and exhibited negative zeta potentials that indicate good stability ofthe nanoformulations.

Future work will focus on loading the nanoparticles with model actives(fluorescently tagged peptides) and studying the release as well as oninvestigating the cytotoxicity of these nanoformulations.

Fig. 4. NTA image of BGE-modified guar gum nanoparticles

▪ Typical characteristics of the nanoparticles obtained (Fig. 4), such as size,zeta potential, and polydispersity index (PDI), are shown in Table 1.

DS = Degree of substitution; A = Integral of the signal assigned to the alkyl chain end CH3 group(0.8 ppm); B = Integral of the signal (ppm) assigned to the anomeric C1 group proton of theglucopyranosic ring (a) 4.8 ppm; b) 5.0 ppm)

References

a)

b)

a) b)

Molar ratio(BGE-GG : stabilizer :

GTA)

Size (nm ± S.D.)

by NTA

Size (nm ± S.D.)

by DLS

PDI by DLS

Zeta potential (mV)

0.28 : 7.14 : 1 216 ± 112 210.80 ± 12.03 0.38 - 20.50 ± 0.30 0.28 : 3.57 : 1 158 ± 66 183.60 ± 4.22 0.20 - 40.20 ± 3.89 0.28 : 1.93 : 1 142 ± 88 194.70 ± 3.16 0.29 - 27.60 ± 1.14

-CH3C-O-C

-CH3

-CH2-CH2

1 : 41 1 : 52 1 : 63 1 : 68 1 : 108

Research Poster

41

Nanoparticles of hydrophobised polysaccharides for drug delivery applications

IntroductionNanotechnology is one of several promising current approaches in developing efficientsystems for intracellular delivery of therapeutic agents that can range from small moleculedrugs to biomacromolecules. One of the critical problems in delivering drug intracellularly isrelated to the protective role of cell membranes that allow only small molecules with high lipidsolubility to pass through. Biocompatibility and ease of chemical modification are attractiveproperties of polymeric nanoparticles and make them suitable for this approach [1]. Thederivatization of polymers with alkylglycerols can increase their hydrophobicity, thus aidingwith the particle penetration across the membrane [2].The aim of this study is to modify biocompatible and biodegradable polysaccharides such asguar gum and pectin (that also have good drug carrier properties and offer functional groupsfor ease of modification) with alkylglycerols and to use these materials for the formulation ofnanocarriers that will be further tested for their suitability in drug delivery applications.

Materials and Methods▪ Guar gum (GG), low esterified pectin (pectin), butyl glycidyl ether (BGE), glutaraldehyde

(GTA), glycerol (stabilizer), span 80, dichloromethane (DCM) are the materials that havebeen used in this study.

▪ To modify the polysaccharides, GG and pectin were treated with BGE in alkalineenvironment at 45oC to yield butylglyceryl derivatives. The resulting products were purifiedby dialysis and characterized by NMR and FT-IR spectroscopic methods. The degree ofsubstitution has been calculated from 1H-NMR spectra.

▪ To formulate the nanoparticles, in-situ polymer crosslinking with GTA was performed in oilin water emulsion (procedure represented below). The diameter of particles wasdetermined by Dynamic Light Scattering (DLS) and Nanoparticulate Tracking Analysis(NTA), and the zeta potential was determined by electrophoretic measurement using aMalvern Zetasizer.

Conclusions

Fig. 2. Preparation and characterization of BGE-modified guar gum : a) Reactionscheme; b) 1H-NMR spectrum (example)

Mohammad F B Bostanudin, Darek Gorecki, Eugen Barbu

0.5% modified

GG (water phase)

2% Span 80 in DCM (oil phase)

emulsion

Stir vigorously

Mix understirring

Glycerol (stabilizer)

25% GTA solution (cross-linker)

Nano-particles

Mix under stirring

Mix under stirring Centrifugation

Fig. 1. Example of FT-IR spectra of non modified guar gum (top) and BGE-modified guargum (bottom)

Table 1. Characteristics of BGE-modified guar gum nanoparticles. (n=3, ± S.D)

0

5

10

15

20

25

30

1.0 : 41.0 1.0 : 52.0 1.0 : 63.0

Deg

ree

of s

ubst

itutio

n (%

)

GG : BGE molar ratio

0

0.5

1

1.5

2

2.5

3

3.5

1.0 : 68.0 1.0 : 108.0

Deg

ree

of s

ubst

itutio

n (%

)

Pectin : BGE molar ratio

Fig. 3. Equations and degree of substitution of : a) guar gum; b) pectin, with BGEusing different ratios. (n=3, ± S.D.)

▪ Pectin and guar gum have been successfully modified with BGE using different ratiosaccording to the chemical reaction described in Fig. 2.

▪ The modifications have been confirmed by 1H- and 13C-NMR and FT-IR spectroscopicmeasurements (examples given in Fig. 1 and Fig. 2).

▪ The degree of substitution has been calculated from 1H-NMR spectra by using theequations in Fig. 3; values in the range 15-23% for guar gum and 1.5-3% for pectin wereobtained.

Results and Discussions

[1]. Nam HY, Kwon SM, Chung H, Lee S-Y, Kwon S-H, Jeon H, et al. Cellularuptake mechanism and intracellular fate of hydrophobically modified glycolchitosan nanoparticles. Journal of Controlled Release. 2009;135(3):259-67.[2]. Lien CF, Molnár E, Toman P, Tsibouklis J, Pilkington GJ, Górecki DC, et al. Invitro assessment of alkylglyceryl-functionalized chitosan nanoparticles aspermeating vectors for the blood-brain barrier. Biomacromolecules.2012;13(4):1067-73.

Guar gum and pectin have been successfully modified with butyl glycidyl ether,with modified guar gum showing higher degree of substitution within the 15-23%range compared to pectin with only 1.5-3% degree of substitution.

Nanoparticles formulated from BGE-modified guar gum were in the size range of100-250 nm and exhibited negative zeta potentials that indicate good stability ofthe nanoformulations.

Future work will focus on loading the nanoparticles with model actives(fluorescently tagged peptides) and studying the release as well as oninvestigating the cytotoxicity of these nanoformulations.

Fig. 4. NTA image of BGE-modified guar gum nanoparticles

▪ Typical characteristics of the nanoparticles obtained (Fig. 4), such as size,zeta potential, and polydispersity index (PDI), are shown in Table 1.

DS = Degree of substitution; A = Integral of the signal assigned to the alkyl chain end CH3 group(0.8 ppm); B = Integral of the signal (ppm) assigned to the anomeric C1 group proton of theglucopyranosic ring (a) 4.8 ppm; b) 5.0 ppm)

References

a)

b)

a) b)

Molar ratio(BGE-GG : stabilizer :

GTA)

Size (nm ± S.D.)

by NTA

Size (nm ± S.D.)

by DLS

PDI by DLS

Zeta potential (mV)

0.28 : 7.14 : 1 216 ± 112 210.80 ± 12.03 0.38 - 20.50 ± 0.30 0.28 : 3.57 : 1 158 ± 66 183.60 ± 4.22 0.20 - 40.20 ± 3.89 0.28 : 1.93 : 1 142 ± 88 194.70 ± 3.16 0.29 - 27.60 ± 1.14

-CH3C-O-C

-CH3

-CH2-CH2

1 : 41 1 : 52 1 : 63 1 : 68 1 : 108

42

International Conference & Exhibition onHolistic Wellness (ICEHW)

Postgraduate Column

Date : 26th November 2016 –SaturdayTime : 8 am- 6 pmVenue : Global Business and Convention Centre PJOrganized by : Sandhya Maarga Holistic Living Academy (SMHLA)

The embracing journey in a Conference and Exhibition of Holistic Wellness served an

opportunity to educate and to create the awareness on the importance of the approach of Holistic Wellness which is more advanced and sweeping the nation’s health sector. Holistic Wellness is an approach which encompasses the body, soul and mind in the pursuit for optimal health.

This conference serves as a platform to bring the health-care personnel, practitioners and students together to share their knowledge and experience for the development and betterment of a person’s lifestyle. Participants were introduced to the practices of both conventional and the different practices of

T&CM (Traditional and Complementary Medicine). Aligned with the theme there were interesting topics that was discussed by panel of 10 international speakers. Examples of the topics are given as follows: -

◊ The growing importance of Traditional and Complementary Medicine

◊ Treating strokes with TCM◊ Optimal nourishment through Raw diet in

Modern times◊ Healing Eczema an Integrative approach◊ How to protect your bones and joints◊ Natural ways to boost fertility◊ The roles of essential oils in Holistic Wellness◊ Aging with strong posture◊ Health benefits of yoga and sattvic food◊ T&CM act and Division

One of the highlights in the event was the exhibition which connects the participants with the health and wellness vendors and exhibitors from all over our

country. There was also a live demonstration on Pranic Healing and also Acupuncture. Many people had one to one sessions with the practitioners for their health concerns.

It was truly a great conference, we as CUCMS post-graduates gained in-depth knowledge on the topic of holistic wellness, which is still being alien for most Malaysians.

By Lydia Devega

43

CGSRC Organization Chart for 2017

CGSRC Highlights

Assoc. Prof. Dr. Muhammad Najib Mohamad AlwiDirector

Dr. Wan Rosalina Wan RosliHead of UnitResearch Management Unit

Dr. Intan Zarina Zainol Abidin

Senior Research OfficerUmmi Nathrah

Abd WadudExecutive

(Postgraduate Administration)

Hidayu Zainal AbidinExecutive

(Research Administration)

Postgraduate by Research Mode Curriculum Review

These curriculum reviews are intended to ensure that curricula of centres and programs continue to meet the educational needs of students and the objectives of the university. In conducting a review, each committee reviewer is asked to reassess its purpose, requirements, and courses, as well as its future directions and goals. CGSRC Curriculum Review was held from 18th Jan to 19th Jan 2017. Only programme by research mode were reviewed. The review involved CGSRC and postgraduate students.

44

Post Graduate Diploma in Addiction Science (PGDAS)

The CUCMS PGDAS has been developed by subject matter experts to be in line with the professional curriculum promoted by the Colombo Plan under the International Centre for Credentialing and Addiction of Education Professionals (ICCE). The Colombo Plan for Cooperative Economic and Social Development in Asia and the Pacific was conceived at the Commonwealth Conference on Foreign Affairs held in Colombo, Ceylon (now Sri Lanka) in January 1950 and was launched on 1 July 1951 as a cooperative venture for the economic and social advancement of the peoples of South and Southeast Asia.

The International Centre for Credentialing and Education of Addiction Professionals had offered fellowship to all these students to undergo a one-year Post Graduate Diploma in Addiction Science (PGDAS) at Cyberjaya University College of Medical Sciences (CUCMS). This is one of the programmes under The Colombo Plan. The registration was held on 1st December 2016 with total of twelve (12) students that come from various countries; Maldives, Pakistan, Botswana, Bhutan, Tanzania, Kenya, Myanmar, and Afghanistan.

Students during the Registration Session

During the welcoming ceremony and speech by the President

PGDAS Class session with AP Dr. Muhammad Najib Mohamad Alwi

45

CGSRC Roadshow

In light of the vision of making CUCMS a fully-fledged university, research is undeniably important in advancing CUCMS to be world-renowned in academic excellence. CGSRC has been at the forefront of making this vision a reality by various efforts to engage and facilitate CUCMS staff to be involved in research. However, the response from CUCMS staff, although good so far, can be greatly improved. One of the key issues identified is the lack of awareness of the roles of CGSRC and the services/programs/incentives that are in place to facilitate research.

Therefore, CGSRC hopes to bridge this gap by organizing a roadshow visiting all faculties to showcase the various opportunities and services offered by CGSRC and also to brief members of CUCMS regarding the MyRA 2016 exercise. The CGSRC Roadshow was held from 19th Jan to 25th January 2017.

The CGSRC roadshow was held at the respective faculties slot as listed below:

Date Session Faculty Venue

19th Janu-ary

10 am – 12.30 pm

FAHS Meeting Room level 1

2.30 pm - 5.30 pm

CFS + CLGS Michael Faraday

23rd Janu-ary

10 am – 12.30 pm

Officiation of CGSRC Research Roadshow by Presi-dentFOM

Auditorium

2.30 pm - 5.30 pm

FTCM Al-Razi

24th Janu-ary

10 am – 12.30 pm

FOSH Al-Razi

25th Janu-ary

10 am – 12.30 pm

FOP Al-Razi

CGSRC Research Roadshow with FAHS

46

CGSRC Research Roadshow with FOP CGSRC Research Roadshow with FTCM

Announcement!!The Re:search Bulletin welcomes submission of research related images to be considered for use

on the cover of future issues.

Please send us your high-resolution images to [email protected]

Announcement!!

47

Officiation of the CGSRC Research Roadshows

The session was held with the academicians from FOM

48

Mark Your CalendarEd

itoria

l Boa

rdfo

r CG

SRC

Re:S

earc

h Bu

lletin

Dr. Wan Rosalina binti Wan RosliChairman; Head, RMU

..........................................................................AP. Dr. Muhammad Najib Mohamed Alwi

Director, CGSRC..........................................................................

Phang Mun Yee Lecturer, CFS

..........................................................................Dr. (H) Faisal Mohammed Hanif

Lecturer, FTCM..........................................................................

Azhar Tajul NoorManager, Library

..........................................................................Farah Azizah Omar

Lecturer, CLGS..........................................................................

Su Natasha Mohamad Lecturer, FAHS

..........................................................................Dr. Siti Nurhafizah Saleeza Ramlee

Asst. Prof., FOSH..........................................................................

Dr. Norfaizatul Shalida OmarAsst. Prof., FOM

..........................................................................Dr. Intan Zarina Zainol Abidin

Senior Research Officer, CGSRC..........................................................................

Dr. Mohd Ehsan Zulazley Bin Abdul RahmanAssistant Professor, FOP

..........................................................................Mr. Jeremy Bishop

Lecturer, CLGS..........................................................................

Hidayu binti Zainal AbidinExecutive, CGSRC

..........................................................................

11th April – Last day submission CRERC (CUCMS Research Ethic Review Committee) Application17th April – Submission 6th Month Progress Report for CRGS20th April – Call for CRGS/CRERC Application26th April – CRERC Meeting

2nd May – Last day submission CRGS Application9th May – Last day submission CRERC Application17th May – SCIRCIR Meeting23rd May – Call for CRERC June Application24th May – CRERC Meeting

15th June – 2nd Postgraduate Research Colloquium (PGRC)16th June – Submission 6th Month Progress Report for CRGS19th June – Call for CRGS Application20th June – Call for CRERC July Application21st June – CRERC Meeting

4th July – Last day submission CRGS Application11th July – Last day submission CRERC Application12th–13th July – Research Enhancement Workshop Series 02/201719th July – SCIRCIR Meeting25th July – Call for CRERC Aug Application26th July – CRERC Meeting

NB: CRERC – CUCMS Research Ethic Review Committee CRGS – CUCMS Research Grant Scheme SCIRCIR – Senate Sub-Committee for Innovation, Research, Commercialization, and Industrial Relation **Subject to change

2017APRIL

2017MAY

2017JUNE

2017JULY

Cyberjaya University College of Medical SciencesNo. 3410, Jalan Teknokrat 3,Cyber 4, 63000, Cyberjaya,Selangor Darul Ehsan

Tel : +603 8313 7000Fax : +603 8313 7001Toll free : 1 800 88 28267

[email protected]

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