Ergogenic Aids Project2013

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    Athletic Performance Cuisine

    CUL 4155

    Chef Poyourow

    Your Name: William Rosetti

    Your Ergogenic Aid: Leucine

    What does it do in the body (3 sentences or less):

    A Branch chain amino acid that helps to stimulate skeletal muscle protein synthesis via activation of the mTOR(mammalian target of Rapamycin) receptor.

    Common Forms of the ergogenic (Pills, powders, rubs, injections etc):

    Pills and protein powders. sed medically intravenously.

    Commercial Claims made about the ergogenic:

    Activates protein synthesis and reduces muscle !reakdown caused !y intense training.

    escribe its legality (*is it banned by any sporting organization or controlled by the DEA)"

    #mpermissi!le !y the $%AA.

    !he Research "tates (bullet statements !"#$ please see ulearn lecture %or details)" Please us only one bullet per study and be sure to cite your wor&'

    o #n one study& dietary supplementation of 'eucine B of *g+day while undertaking intensiveresistance training resulted in increased strength and deposition of fat,free mass. (ero)

    o elps to prevent fatigue& -, week / *g supplementation per day prevented -0 plasma

    glutamine loss seen in place!o group of triathlon study. (1leeson)o ay cause kidney damage& increased !lood lipoprotein levels& and dehydration (1leeson)

    23g of peanuts (4+ cup) has same B%AA levels as 44 ta!lets of current supplements

    4 chicken !reast (433g) is the e5uivalent to 6 commercial supplement ta!lets

    $oted that *7 the daily recommended dosage has not !een found to cause issues

    o elpful for preserving muscle mass in aged persons (elderly particularly)& not as effective in

    younger population& as seen from the rat muscle study. (%om!aret)o B%AA ('eucine in particular) when consumed in a diet containing other essential amino acids

    have !een linked to weight loss& !ody fat loss& muscle protein synthesis& and decreased plasmainsulin& especially through the consumption of dairy products high in protein. (8t9el)

    o $eonatal pigs study shows that leucine increases protein synthesis in muscles& and liver protein

    synthesis& !ut that it is limited !y the other 8AA concentrations in the !ody. (8sco!ar)o :tudy of resistance training athletes that trained for ;,minutes& then supplemented with *3g of

    either %O

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    o you su##ort this ergogenic for athletes (yes$no):

    >es ? no.

    Why: #t does not seem useful for an athlete whom is healthy& as well as eating and training properly.

    @or someone whom may !e coming off of an inury or surgery& 'eucine (more particularly B%AAsupplementation) may !e useful in the regeneration of muscle and the healing process fromreha!ilitation. #t is currently used in the medical field for !urn victims to help with cellular repair.

    ore long term research needs to !e conducted.

    %f you do su##ort this ergogenic& for 'hat #o#ulation of athlete do you su##ort its use at

    'hat dosage:o

    *mg$+g$day current EAR for ,CAA in ratio of -:.:. Leucine:/aline:isoleucineo 0--mg$+g$day seemingly more accurate EAR for athletes (WE,1)

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    1LA Formatted Wor+s Cited 2age

    Combaret, Lydie. "A Leucine-supplemented Diet Restores the Defective Postprandial Inhibition of Proteasome-

    dependent Proteolysis in Aged Rat Skeletal Muscle."A Leucine-supplemented Diet Restores the Defective

    Postprandial Inhibition of Proteasome-dependent Proteolysis in Aged Rat Skeletal Muscle. Journal of Physiology,

    2005. Web. 27 Oct. 2014. .

    Escobar, Jefferey. "Physiological Rise in Plasma Leucine Stimulates Muscle Protein Synthesis in Neonatal Pigs by

    Enhancing Translation Initiation Factor Activation."Physiological Rise in Plasma Leucine Stimulates Muscle

    Protein Synthesis in Neonatal Pigs by Enhancing Translation Initiation Factor Activation. American Journal of

    Physiology, 1 May 2004. Web. 27 Oct. 2014. .

    Etzel, Mark. "Manufacture and Use of Dairy Protein Fractions."Manufacture and Use of Dairy Protein Fractions.

    Journal of Nutrition, 1 Apr. 2004. Web. 27 Oct. 2014. .

    Gleeson, Micheal. "Interrelationship between Physical Activity and Branched-Chain Amino Acids."Interrelationship

    between Physical Activity and Branched-Chain Amino Acids. Journal of Nutrition, 1 June 2005. Web. 27 Oct. 2014

    .

    Mero, A. "Result Filters."National Center for Biotechnology Information. U.S. National Library of Medicine, 27 June

    1999. Web. 27 Oct. 2014. .

    Norton, Layne. "The Anabolic Trigger!"It Has Been Shown That in Order for Protein Balance to Become Positive

    Post Workout, Dietary Protein, Specifically the Amino Acid Leucine, Must Be Consumed.Bodybuilding.com, 1 Nov.

    2013. Web. 27 Oct. 2014. .

    "WebMD."WebMD. WebMD, n.d. Web. 27 Oct. 2014. .