©2013 Waters Corporation 1

Empower Instrument Control

Anders Janesten

Informatics & Instrument Sales Specialist, SW/NO

Nordic User Training 2013, Jurmala

©2013 Waters Corporation 2

Topics

Instrument Control Overview

DANI Instruments GC and Headspace

Agilent Infinity LC Control Project

Agilent 7890 GC projects

Agilent 6850 GC projects

Beckman CE project

Agilent Headspace 7697

ACQUITY Driver Pack 4

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Versatility

In an environment configured for compliance, Empower

Software lets you collect data and control different

instrumentation such as LC, GC, SFC and CE with

advanced detection techniques such as Mass Detection

and Photo Diode Array.

Empower Software extends beyond traditional

chromatography to include integrated applications such

as Dissolution, Method Validation, Integrated Chemical

Structures, Polymer Analysis and Fusion Method

Development Software.

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Instrument Control – Drivers

Provide a comprehensive, reliable and robust feature set for each instrument we support.

– Waters works closely with its customers to ensure the instruments supported with Empower Software provide the scientist the capabilities to realize the most value from their instrument investment.

Instrument Driver Approach - Open Instrument Portal (OIP) – Similar to the Microsoft Printer driver approach

– Allows creation of software plug-ins to add hardware control capabilities

– Waters uses its own and other instrument vendors resources to create instrument control

– This allows the laboratory to introduce new hardware without changing the base Empower software application.

Instrument Control Software (ICS), Instrument Control Option Pack (ICOP), Driver Pack (DP)

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Instrument Control – Driver Support

Agilent Instrument Control Framework

(ICF)

– Instrument control written and supported by

the instrument vendor

– Can be used by all CDS systems

– Allows faster integration with third-party

CDS systems

– Requires development of a “dock” for the

“ship”

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Extended Instrument Control with Empower Software

Benefit to the Customers: One Software solution for all chromatographic systems

– Consistent Documentation

– Reduced Training, Validation, and Support

Available Today

– 15 Vendors with over 345 Instruments

– Instrument Control Available from major LC Vendors including Waters, Agilent, Shimadzu, Hitachi, and Thermo

– Instrument Control Available from major GC Vendors including DANI, Agilent, Shimadzu, and PerkinElmer (Varian)

New instrument control

– DANI GC and Headspace

– Agilent 6850 GC V1.30

– Agilent ICF v2.1/A.01.05

– Thermo Dionex IC

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Mass Detection Waters SQD & TQD

Data acquisition and

instrument control of Mass

Detectors.

Greater specificity of

analysis.

Easily use MS and MS/MS

in QC and Development

lab environments.

Empower is the first Chromatography Software to offer Tandem MS control and data processing in a network or regulated environment

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Empower 3 MS Ion Ratios + Acceptance Tolerance

– For defensible compound confirmation

– Area or Height ratio of 10 Channel : 20 Channel (1 – 4) in same injection

– Acceptance tolerance on result as compared to a reference injection

– Failed values are faulted

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Empower 3 MS Target Masses

Open Access, Run Samples, QuickStart, Alter Sample

Specify up to 5 base monoisotopic masses in sample table

(not processing method)

Possible adducts entered in PM

Obtain Yes/No answer as to

whether the target mass is

present in sample

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Empower 3 MS Target Masses

Masses specified in Run Samples supersede the one in the

processing method

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Empower 3 ACQUITY eCord Information

Summary information

– Injection Count

– Date Of First Injection

– Date Of Last Injection

– Sample Count

– Maximum Pressure

– Maximum Temperature

Information updated after each

injection

Requires updated ICS (driver)

Sample Set Information

Date

Sample Set Name

User Name

System Name

Injection Count

Sample Count

Max Pressure

Max Temperature

Sample Set Complete

Injection information –

associated with injections

eCord Name

Serial Number

Injection Count

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Empower 3 ACQUITY eCord Information

eCord data viewed and managed in

Configuration Manager

– eCord Summary Table

– eCord Sample Sets table

New eCords are added automatically

when data is acquired using a system containing the eCord

Enumerated custom fields called Column Name and Column

Serial Number (for non-ACQUITY systems)

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Empower 3 WFCIII

Basic WFC III control in Empower 2

Enhancements in Empower 3

– Fraction annotations on chromatogram

– Fraction table

– Fraction tab in Project window

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Agilent Infinity LC Control Projects

Agilent ICF Support v2.1 Hotfix 1 project using Agilent ICF

version A.01.04 released April 10, 2013 and available

ICF version A.01.05 completed testing March 29, 2013 and

available

Highlights:

– Multi-system

– Multi-detector

– Transparent ICF updates

– Fraction collection

– Sample Pretreatment

– Windows Server 2008 support

– Defect corrections

ICF A.01.05 SP1 in test

Next ICF Support project in discussion

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Agilent Infinity LC Control

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Agilent Infinity LC Control

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Agilent Infinity LC Control

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Agilent 7890 GC Projects

V2.5

– Released February, 2012

– Minimum: Empower 2 FR3 required

– Advanced Detector support

o Nitrogen Phosphorus Detector (NPD)

o Sulfur Chemiluminescence Detector (SCD)

o Nitrogen Chemiluminescence Detector (NCD)

o Enhanced Flame Photometric Detector (Enhanced FPD)

– Dual-tower support requires Empower changes (Empower 2 SP H

Hotfix 1 or Empower 3 FR1)

Agilent 7890B compatibility

– 7890B is runs as 7890A

– Additional capabilities under discussion

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Agilent 6850 GC ICS v1.30

Released December, 2012

– Oven ramp/SQT fix

– Support for 7693 injector basic injection capabilities

– Firmware A.06.02

– Series I still requires Equinox card (XP)

Next project, v1.40, is starting

Planned for v1.40:

– Avocent Hub support

– Micro ECD support

– Support for Fast, Slow, Variable injector speed

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Beckman CE Systems

Driver version 1.1.5 is available for Empower 2 and Empower 3

Supports Beckman P/ACE MDQ, PA-800, and PA-800 plus

Capillary Electrophoresis Systems

Control includes photo diode array and selectable-wavelength

UV/Vis (200, 214, 254 and 280 nm filters included) detector, UV

source optics, temperature-controlled sample storage module

and Laser Induced Fluorescence (LIF) Detector

Beckman CE Control License

– Includes the instrument control software, license, documentation,

and an IEEE-to-Ethernet converter in order to connect the Beckman

CE (IEEE-488) to a computer via Ethernet.

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Beckman CE Control

Version 1.2.0 under development

– Auto-increment

– Calibrate PDA

– LIF Calibration Correction Factor

– Multi-system (2)

– Localization to J, C, K

– Defect fixes

– Target: October release

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Agilent HS7697 Headspace Sampler

Project delayed by legal issues, now resolved

Target is TBD.

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ACQUITY UPLC Driver Pack 4 (V1.6)

DP2

DP2 Supp2

DP3

DP4

DP4

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