Elderly Medication Adherence Monitoring with the Internet...

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X. Toh, H. X. Tan , H. Liang and H. P. Tan Singapore Management University, Singapore Institute for High Performance Computing, A*STAR, Singapore Elderly Medication Adherence Monitoring with the Internet of Things

Transcript of Elderly Medication Adherence Monitoring with the Internet...

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X. Toh, H. X. Tan, H. Liang and H. P. Tan

Singapore Management University, Singapore

Institute for High Performance Computing, A*STAR, Singapore

Elderly Medication Adherence Monitoring with the Internet of Things

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220,000

440,000

900,000

0

200,000

400,000

600,000

800,000

1,000,000

Elderly Aged Above 65 Years Old

2000 2015 2030

35,000

83,000

0

20,000

40,000

60,000

80,000

100,000

Elderly Living Alone

2012 2030

National Population And Talent Division, Singapore

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Enabling Ageing-In-Place through Technology

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(e.g. sensor-enabled homes)

Supported by the Singapore Ministry of National Development (MND) and National Research Foundation

(NRF) under L2NIC Award No. L2NICCFP1-2013-5.

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Medication non-adherence leads to:

Importance of Monitoring Medication Adherence

Health issues and reduced effectiveness of treatment

Vulnerability to adverse complications

Increased healthcare expenditure, morbidity and mortality

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Expensive with recurring costs

Cannot be customized to

consumption habits

Non-interoperable with other sensing devices

Non-integrated with personalized care model

Limitations of Existing Products

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Existing medication habits of elderly

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A Solution for Inferring Medication Adherence

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Currently, the only way to accurately detect medication adherence is through image-based solutions or ingestible medicine.

Medication box that can be personalized

Unobtrusive and non-instrusive

Allows real-time monitoring, for reactive intervention by caregivers

Allows longitudinal monitoring, for pre-emptive intervention by caregivers

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Hardware components MedBox MedBox

Medication Box Prototype

(Normally Closed) Reed SwitchArduino Fio (microcontroller)Xbee radio (IEEE 802.15.4)LiPo battery

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Packet Transmission Schedule in MedBox Sensor

Reed switch breaks contact with magnet, board is powered on

Multiple pkt txn for redundancy and reliability

Sleep period to conserve energy

Continued txn to indicate that box is

not closed

Reed switch makes contact with magnet, board is powered off

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Hardware components

Medication Box Gateway

Beaglebone BlackXbee radio (IEEE 802.15.4)3G dongle + SIM card

Receive pktsfrom sensor(s)

Publish data to backend

through MQTT

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Density-Based Spatial Clustering of Applications with Noise (DBSCAN) to cluster medication intake timings

Distance function :: cyclic difference between any two medication intake timings

= 1 hr :: maximum distance between two medication intake timings that can be considered to be in the same cluster

MinPts = 5 :: minimum number of points in cluster (-neighborhood)

Descriptive statistics to deduce regularity of inferred medication intake frequency

Monitoring and Analysis

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System Architecture

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*Anycast routing is used for reliability and robustness, as well as to decrease cost.

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Elderly Care Model

Survey Data

(With Periodic

Updates)

Sensor Data

Long Term

Monitoring &

Data Analysis

Elderly

Categorization

AdheringNon-Adhering

Irregular Medication Intake Regular Medication Intake

Medical

Reconciliation

and Intervention

by Care-Givers

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10 elderly

69 to 81 years old

3 to 8 chronic illnesses

4 to 10 types of

medication

Daily intake frequency between 1

to 3

Participant Profile

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Inferred Medication Intake Frequency

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Elderly 1090

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Inferred Medication Intake Frequency

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Elderly 1070

hospitalization

outdoor activities on Sundays

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Medication Intake Timings

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Elderly 1060

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Ground Truth Evaluation

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Two-Week Medication Diary

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Elderly are concerned about electrical consumption of mains-powered gateway

Elderly with active lifestyles tend to upset daily medication routine

Only medication consumption can be inferred

Dosage and type of medication cannot be monitored

Discussion and Insights

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Single-compartment Triple-compartment

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Increase duration and scale of study to derive both longitudinal and transversal insights in medication adherence

Work more closely with caregivers and medical professionals to better provide holistic care model

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Thoughts?

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Hwee-Xian [email protected]

SMU-TCS iCity Lab, Singapore