DNA double helix & replicationExperimental evidence for DNA as genetic materialSection 1\Section A\The Discovery of DNA - The beginning of it all.mp4Section 1\Section A\DNA Carries the Genetic Material.mp4DNA double helix discovery

Complete questions 1 and 2 of Activity 1.Activity 1

http://cronodon.com/BioTech/Cell_Nucleus.htmlThe structure of DNAThe Chemical structure of DNANucleotides in DNA | Science Primer

B DNA and Z DNA

Activity 2

Linear and circular DNA, Single-stranded and double-stranded

Most prokaryotic organisms have a closed circular double-stranded DNA, i.e., their DNA essentially has no ends. It assumes a twisted shape and is termed type I. Type II DNA is rare in nature; the DNA chains have a break, thus eliminating the twist. The nuclear DNA of eukaryotic organisms is a linear double-stranded DNA (type III) with two ends. DNA shape in nature is a major difference between prokaryotic and eukaryotic organisms http://csls-text3.c.u-tokyo.ac.jp/active/06_05.htmlHow DNA encoded information governs expression of phenotype

RNA

ACTIVITY 33.1 Answer the questions on SciencePrimer.com

3.2 Tabulate the difference between RNA and DNA.

Restriction enzymes can protect bacteria against viral DNA

Activity of restriction and methylase enzymes. Restriction enzyme EcoRI cleaves within the recognition sequence if the DNA is unmethylated. On methylation by methylases, the restriction enzyme EcoRI is inhibited from cleaving within the restriction site.RECOMBINANT DNA

DNA REPLICATION

Semi-conservative nature of DNA replication.Meselson-Stahl experiment

ACTIVITY 5EnzymeFunctionDNA topoisomeraseDNA gyraseDNA helicaseDNA polymerase IDNA polymerase IIIDNA ligaseRNA primaseDNA ReplicationAnimation 1Animation 2

Quiz

http://upload.wikimedia.org/wikipedia/commons/thumb/6/6f/DNA_polymerase.svg/200px-DNA_polymerase.svg.png

DNA polymerase Animation 1

DNA Topoisomerases