Development & anomalies respiratory system embryology

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Respiratory system Development & anomalies Maj Rishi Pokhrel, MD Anatomy NAIHS www.slideshare.net

Transcript of Development & anomalies respiratory system embryology

Page 1: Development & anomalies respiratory system embryology

Respiratory systemDevelopment & anomalies

Maj Rishi Pokhrel, MDAnatomy

NAIHSwww.slideshare.net

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What triggers labor of childbirth?

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Respiratory diverticulum

25 Day embryo

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Partition of tubes

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Larynx

6 week 12 week

4th arch: superior laryngeal N 6th arch: superior laryngeal N

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Trachea, bronchi & lungs

Prenatal: 17 generationsPostnatal: 6 generations

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• Epithelium: endoderm• Cartilage, muscles, connective tissue:

mesoderm

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Pleural cavity

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Maturation of lungs

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DEVELOPMENT OF DIAPHRAGM

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Defects in partition of foregutesophageal atresia / Tracheo-esophagal fistula

Total Incidence: 1/3000

90%4%4%

1% 1%

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VACTERAL association

• V: Vertebral anomalies• A: Anal atresia• C: cardiac defects• E: esophageal atresia• R: renal anomalies• L: limb defects

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• Respiratory distress syndrome / hyaline membrane disease

• Ectopic lung lobes• Congenital cysts of lungs

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Assignment

• Poly-hydraminos?• Oligo-hydraminos?

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