DENNIS EDWIN DOHERTY, M.D., FCCP CHIEF OF · PDF filecurriculum vitae dennis edwin doherty,...

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Dennis E. Doherty, M.D. 1

CURRICULUM VITAE

DENNIS EDWIN DOHERTY, M.D., FCCP

CHIEF OF PULMONARY FUNCTION LABORATORY

LEXINGTON VETERANS ADMINISTRATION CENTER

PROFESSOR OF MEDICINE

DIVISION OF PULMONARY, CRITICAL CARE, AND SLEEP MEDICINE

UNIVERSITY OF KENTUCKY MEDICAL CENTER

I. PERSONAL DATA

Office Address: University of Kentucky Chandler Medical Center, Division of Pulmonary, Critical Care and

Sleep Medicine, 740 S. Limestone, Room L-543, Lexington, Kentucky 40536-0284

Office Phone: 859/323-5944 Office FAX: 859/257-6788

Certifications: Internal Medicine, Pulmonary Medicine

II. EDUCATION

1973-1977: B.A. in Science - The Johns Hopkins University

1977-1980: M.D. - Ohio State College of Medicine

1980-1981: Internship in Internal Medicine - Ohio State University Hospitals

1981-1983: Residency in Internal Medicine - Ohio State University Hospitals

1983-1986: Fellowship in Pulmonary and Critical Care Medicine - University of Colorado Health

Sciences Center and The National Jewish Center for Immunology and Respiratory

Medicine

9/15/97: Media Training - Powell and Tate, Inc.

1998: Executive Leadership Development for Medical Professionals Course - University of

Kentucky Carol Gatton College of Business and Economics

11/12/99: Navigating the Clinical Research Process: Clinical Investigator Training Series -

University of Kentucky College of Medicine

6/2000: Public Speaking Course- Communications skills: Techniques and Strategies,

Coram Associates Inc.

1/11/14: Problem-Based Learning training by the Problem Based Learning Institute, St. Louis, MO

III. PROFESSIONAL EXPERIENCE

Teaching Hospital Positions:

1996-present: University of Kentucky Medical Center - Pulmonary consults and ICU attending

1996-present: Lexington Veterans Administration Medical Center - Pulmonary Medicine, ICU, and

General Medicine Staff Physician

1986-1996: Denver Veterans Administration Medical Center - Pulmonary Medicine, ICU , and

General Medicine Staff Physician

1986-1996: National Jewish Center for Immunology and Respiratory Medicine - Pulmonary

Consultant, PI on IPF SCOR, Co-PI on Clinical Project of IPF SCOR

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Academic Titles:

2011-present: Chief of Pulmonary Function Laboratory, Lexington Veterans Administration Medical Ctr

2007-2011: Chief of Medicine, Lexington Veterans Administration Medical Center

Professor of Medicine University of Kentucky Medical Center (tenured)

1996-2007: Chief, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Kentucky

Medical Center

1996-present: Lexington Veterans Administration Medical Center and University of Kentucky –

Professor of Medicine, Staff MD

1996-present: University of Kentucky – Professor of Medicine (tenured)

1986-1996: Denver-Eastern Colorado Veterans Administration Medical Center – Staff Physician

1992-1996: University of Colorado School of Medicine - Associate Professor of Medicine (tenured)

1986-1992: University of Colorado School of Medicine - Assistant Professor of Medicine

Research Positions:

1996-present: Principal Investigator of Veterans Administration, National Institutes of Health (NIH),

and American Lung Association, and Clinical Pharmaceutical Research Grants-

Research conducted at University of Kentucky Medical Center and Lexington VAMC

1986-1996: Principal Investigator of NIH, NHLBI, Veterans Administration, and American Lung

Association Research Grants - Research conducted at the National Jewish Center for

Immunology and Respiratory Medicine, Denver, Colorado

1984-86: Research fellow at the National Jewish Center for Immunology and Respiratory

Medicine, Denver, Colorado - Dr. Peter Henson (mentor)

1975-1977: Research Assistant at The Baltimore Cancer Research Center, NIH, NCI, Baltimore,

Maryland - Drs. Carl Levy and Edward Neuwelt (mentors)

IV. HONORS

1981: Elected member of the Ohio State Landacre Society (excellence in medical research)

1986-1991: Clinical Investigator Award NIH, NHLBI

1988: Teaching Award - Introduction to Clinical Medicine Basic Physical Exam Publications

1993: Elected to the Western Society for Clinical Investigation

1991-1996: Veteran's Administration Clinical Investigator Award

1998: Elected to the Central Society for Clinical Research

1999-present: Endowed Professorship in Pulmonary Medicine- KY Research Challenge Trust Fund

Oct. 2000: Presented with the “Key to the City of Cincinnati” for public service work in raising

public awareness to Chronic Obstructive Pulmonary Disease (COPD)

Jan 2002: Certificate of Recognition from Governor Jesse Ventura and the State of Minnesota and

from Mayor Randy Kelly and the city of St. Paul, MN for Public Service activities in

raising awareness of Chronic Obstructive Lung Disease

March 2002: Certificate of recognition from the Kentucky State Senate for public service activities

throughout the Commonwealth of Kentucky in the area of Chronic Obstructive Lung

Disease (Kentucky Colonel).

2002: 2002 winner of the national Telly Award (honors the finest video and film

productions) - Category: Best Medical Education Video- “COPD: New Concepts in

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Disease Management, Global Initiative for Chronic Obstructive Lung Disease

(GOLD) Guidelines and Changes in Management Concepts” (>11,000 nominations)

2003: America’s Top Doctors – selected by Castle Connolly Medical Ltd. via peer survey for

inclusion in the 2nd

edition (2003) as one of America’s top doctors in Pulmonary and

Critical Care Medicine

2003: Appointed to the Honorable Order of Kentucky Colonels by Governor Paul E. Patton for

outstanding accomplishments that contribute to the advancement of Kentucky and

Kentuckians

2004: Elected by peers to the Board of Directors for the National Association for Medical

Direction of Respiratory Care (NAMDRC)


inclusion in the 3rd



2004: Elected by peers to the Executive Committee of the U.S. COPD Coalition


inclusion in the 4th



2005: Finalist – 2005 national Telly Award (honors the finest video and film productions)

Category: Best Medical Education Video- “COPD Exchange Education CD” (>12,000

nominations)

2005-2006: Best Doctors in America – elected by peers to the listing in Pulmonary 2005-2006





2007: Certificate of Recognition from University of Kentucky - Presidents’ Awards for Diversity

– “for outstanding commitment and unyielding dedication to improving diversity at the

University of Kentucky”

2007: American Thoracic Society designated the National Lung Health Education Program

(NLHEP) web site as “Best Web Sites for COPD”. The web site was one of eight web sites

chosen from all COPD related web sites available on the web (as of June 2007) as

“authoritative and represent a major endeavor by a group of recognized experts to consider

and distill information into useful and accessible guides”. Dr. Doherty- Chairman NLHEP.










2009: Elected by peers to serve as Secretary-Treasurer for the National Association for Medical

Direction of Respiratory Care (NAMDRC), a position that ascends to the Presidency

2009: Finalist – 2009 Freddie Award- International Health and Medical Media Awards -

Category: Inflammatory Diseases Best Medical Education Video- “Pulmonary

Perspectives: Focus on Management of COPD”





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2011: Elected by peers to serve as President-Elect for the National Association for Medical

Direction of Respiratory Care (NAMDRC), a position that ascends to the Presidency










2012: U.S. News and World Report – Listed in the top 1% of U.S. pulmonologists (based on peer

nomination)

2012: Distinguished Scientific Contribution Annual Award- International Symposium on

Respiratory Diseases-American Thoracic Society Conference, Shanghai, China

2013: Best Doctors in America – elected by peers to the listing in Pulmonary 2013





2013: 2013: U.S. News and World Report – Listed in the top 1% of U.S. pulmonologists (based

on peer nomination)

2014: Best Doctors in America – elected by peers to the listing in Pulmonary 2014









2015-2016: Best Doctors in America – elected by peers to the listing in Pulmonary and COPD 2015-

2016

2015: Alumni Achievement Award Recipient, The Ohio State College of Medicine-

acknowledgement of distinguished career achievements, both in contributions to the

practice of medicine and to society as a whole

V. PROFESSIONAL AFFLIATIONS/MEMBERSHIP

1982-2009: American College of Physicians

1983-present: American Thoracic Society

1984-present: American College of Chest Physicians (FCCP)

1984-present: Colorado Trudeau Society

1988-2008: American Association for the Advancement of Science

1992-2008: American Society for Cell Biology

1993-present: Western Society for Clinical Investigation

1993-present: Society for Quantitative Morphology

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1997-present: Fayette County Medical Society

1997-present: Kentucky Medical Association

1998-present: Central Society for Clinical Research

1999-present: Member of the United States Pharmacopeia Society (U.S.P.)

2000-present: Member of the American Association for Respiratory Care

2001-present: Member of the National Association for Medical Direction of Respiratory Care

2004-present: Member of the National Respiratory Training Center

2004-2008: Member of Southern Medical Association

VI. PROFESSIONAL SERVICE AND COMMITTEES

A. Institutional and Departmental Committees

1991-1992: Acting Director of the Pulmonary Function Laboratory at the Denver VA Hospital

1991-1996: Director-Quality Improvement Committee, Division of Respiratory Care, Denver VA

1991-1996: Pulmonary Sciences Division Clinical Teaching Committee

1992-1996: Director of Image Analysis Workstation, National Jewish Center for Immunology

and Respiratory Medicine

1992-1996: Denver VA Research Protocol Review Committee

1993-1996: Member of Fellowship Selection Committee Univ. of Colorado Health Sciences

Center Division of Pulmonary Sciences and Critical Care Medicine

1995-1996: Member of the Executive Research Review Committee Univ. of Colorado Health

Sciences Center Division of Pulmonary Sciences and Critical Care Medicine

1996-1999: Member of UK Department of Medicine Chairman's Advisory Committee

1996-1999: Member of UK Department of Medicine Executive Council

1996-1999: Member of UK Department of Medicine Practice Plan Task Force Committee

1997-2001: Member of University of Kentucky College of Medicine Research Committee

1996-2001: Member of Veterans Administration Animal Protocol Review Committee

1998-2001: Member of Veterans Administration Research and Development Committee

2000-2001: Co-Chairman, Lexington VA Critical Care Committee

2003-2006 Member of the UK College of Medicine faculty Appointments, Promotions and Tenure

Committee

1996-2008: Member of GCRC Advisory Committee

1996-2008: Member of GCRC Protocol Review Subcommittee (ad hoc)

1996-2002: Member of Executive Development Program Focus Group

1997-2000: Member of the Board of Directors, Dept. of Internal Medicine, Univ. of Kentucky

1998-2002: Member of Advisory Board for the Kentucky Center for Clinical Research and

Investigator Services (KCCRIS)

2000-2007: Member of Lung Transplant Program Executive Steering Committee

2005: Task Force- Internal Medicine Residency Program Review

2006: Member of the Steering Committee -University of Kentucky HealthCare Enterprise

Transplant Center Strategic Planning, and Member of the Operation and Throughput Work

Group

2007: Member of the University of Kentucky Lung Transplantation Outreach Task Force

2007-2010: Chairman, Rapid Response Team Committee, Lexington VAMC

2009-2010: IPEC Mortality Task Force

2007-2011: Professional Standards Board, Lexington VAMC

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2007-2011: VA-UK Affiliation Partnership Council, Lexington VAMC

2007-2011: Internal Performance Measures Committee, Lexington VAMC

2007-2011: Performance Improvement Council, Lexington VAMC

2007-2011: Utilization Management/Review Committee, Lexington VAMC

2007-2011: Utilization Management Committee, Lexington VAMC

2007-2011: Integrated Ethics Council, Lexington VAMC

2007-2011: Co- Chairman, Medical Records Committee, Lexington VAMC

2007-2011: Clinical Executive Council, Lexington VAMC

2007-2011: Executive Leadership Board, Lexington VAMC

2007-2011: Quality Council, Lexington VAMC

2008-2011: Peer Review Committee, Lexington VAMC

2009-2011: Patient Centered Care Council, Lexington VAMC

2010-2011: Tissue Committee, Lexington VAMC

2010-2011: Equipment Committee, Lexington VAMC

2010-2011: Executive Committee of the Medical Staff, Lexington VAMC

2010-2011: Clinical Informatics Committee, Lexington VAMC

2011-2011: Inpatient Flow Committee, Lexington VAMC

2011-2011: Pain Committee, Lexington VAMC

2011-2011: Invasive Procedure Committee, Lexington VAMC

2011-2011: Space Committee, Lexington VAMC

2002-present Member of the Veterans Administration Compliance Committee, Lexington VAMC

B. Regional Service

1996-present: Advisory Member of the American Lung Association of Kentucky Research

Future Cures Through Education and Research Task Force

1996-present: Member- Research Grant Review Subcommittee American Lung Association of KY

1998-2000: President-elect of the Kentucky Chapter of the American Thoracic Society

1998-99: Co-Chairman of the Annual American Lung Association of Kentucky/Kentucky

Thoracic Society Annual Medical Conference

1998-present: Planning Committee, Annual meeting of the Kentucky Chapters of the

American Lung Association and American Thoracic Society

2000-2007: Member, American Lung Association of Kentucky Board of Directors

2000-present: President of the Kentucky Chapter of the American Thoracic Society

C. National Service

Ad hoc: Reviewer for National Institutes of Health, NHLBI - program project grants

Ad hoc: External Reviewer for Department of Veterans Administration Medical Research Merit

Review Grant Board-Respiration Section

Ad hoc: Reviewer for Norman Salvesen Emphysema Research Trust Grants

1992-present: Committee Member: American Thoracic Society-Allergy, Immunology, and

Inflammation Assembly

1997-2002: Elected member of the Second Decade Society- a leadership and development

organization of The Johns Hopkins University Zanvyl Kreiger School of Arts and

Sciences

5/25/94: Chairman American Thoracic Society Conf. - Session: Mononuclear Cell

Inflammation

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5/13/96: Chairman American Thoracic Society Conf. - Session: Cellular Mechanisms of

Lung Injury

5/20/97: Chairman American Thoracic Society Conf. - Session: Macrophages and

Inflammation

1998-99: Chairman of the University HealthSystem Consortium (UHC) Pulmonary/Critical

Care Clinical Investigator Network

1998-present: Member on the Executive Committee for the National Lung Health Education

Program (NLHEP)

2000-2004: National Co-Chairman, National Lung Health Education Program

2002-2003: Co-Chairman Program Planning Committee for the first National COPD Conference 2003

2003: NIH, NLHBI Special Emphasis Panel Review of RFA- COPD Clinical Research Network

2000-2004: The Johns Hopkins University Alumni Council (Elected Member)

1999-2005t: Member, Professional Assisted Cessation Therapy (PACT) Committee

2001-present: Member of the US COPD Coalition

2004-2012: Elected to the Executive Committee/Board of Directors of the U.S. COPD Coalition

Re-elected in 2008 for a second term.

2002-present: American Thoracic Society Council- KY Chapter Representatives

2003-2009: Member, American Thoracic Society Communications and Marketing Committee

2004-2008: National Chairman, National Lung Health Education Program

2004-present: Board of Directors of the National Association for Medical Direction of

Respiratory Care (Elected by peers)

2004-present: Elected to the Board of Directors of the National Respiratory Training Center

2004: NIH, NHLBI Long-term oxygen treatment in COPD. Member of working group.

2004: NIH, NHLBI Educational Strategy Development Workshop on Chronic Obstructive

Pulmonary Disease (COPD)

2005: Co-Chair of the Sixth Long-Term Oxygen Consensus Conference (published 2006)

2005-2007: American Thoracic Society Strategic Planning Committee - Member. Committee is

responsible for all aspects of the Society’s operations: structure, specific activities, and

long-range goals. Committee oversees the Strategic Planning of the Society

2005-present: American Thoracic Society Spirometry Task Force – Member

2005-2010: United States Pharmacopeia Society (U.S.P.) Membership Committee Member

2006-2007: Secretary of the Council of Chapter Representatives for the American Thoracic Society-

American Lung Association State Chapters- elected by peers

2006-2007: Conducted in person meetings with the head of Centers for Medicare-Medicaid Services

(CMS, Mr. Lawrence and staff) with regard to reimbursement structure and modality-

neutral to modality-specific transition in CMS reimbursement

2006-2007: Veterans Administration /Department of Defense National Chronic Obstructive Pulmonary

Disease (COPD) Clinical Practice Guidelines – member of the writing committee

2007-2012: Steering Committee and Protocol Writing Committee member for NIH-NHLBI/Centers for

Medicare and Medicaid Clinical trial Research Network – Long-term Oxygen Treatment

trial (14 Clinical Centers in U.S.)

2007-2008: Chairman-Elect, American Thoracic Society-American Lung Association Council of

Chapter Representatives – elected by peers

2007-2009 American Thoracic Society Clinicians Advisory Committee - Member

2007-2009: American Thoracic Society Board of Directors

2007 Jan.: Capitol Hill Day for American Thoracic Society – visited members of the U.S. House and

Senate discussing pending legislation on: Critical Care Doctor Work-Force, National and

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International Tuberculosis Control, FDA Control of Tobacco Products, Pulmonary

Rehabilitation medical Coverage- Global Reimbursement

2007-2010: American Thoracic Society Clinicians Advisory Committee

2007-2008: American Thoracic Society Workforce Congressional Action Team Subcommittee – a

subcommittee of the Health Care Policy Committee

2008-2009: American Thoracic Society Foundation – Board of Directors

2008-2009: American Thoracic Society Foundation – Nominating Committee member

2008-2009: Chairman, American Thoracic Society-American Lung Association Council of Chapter

Representatives – elected by peers

2008-present: Secretary, National Lung Health Education Program

2009-2015: National Home Oxygen Patient Association (NHOPA)- Physician Board Member (elected

five terms)

2009-2011: Secretary-Treasurer, National Association for Medical Direction of Respiratory Care

(NAMDRC)

2010-2011: American Thoracic Society Documents Development and Implementation Committee

2010 Co-Chair for North America - World Spirometry Day in conjunction with ERS/ATS in The

Year of the Lung

2010-2015: United States Pharmacopeia Society (U.S.P.) Nomenclature, Safety and Labeling

Committee Member

2011-2013: President-Elect, National Association for Medical Direction of Respiratory Care

(NAMDRC)

2011-2015: American Thoracic Society Planning and Budget (Finance) Committee Member (Two

terms)

2011- present: External Advisor, Steering Committee: Thomas L. Petty Aspen Lung Conference

2011-2012: Fibrosis Across Organ Systems Symposia – Planning Committee member and Group

Leader, March 8-11, 2012, Denver, CO. Conference bringing together a core of experts in

lung, skin, liver, and heart fibrosis to develop a Road Map for future basic and clinical

research in fibrosis. In cooperation with the American Thoracic Society and the National

Institutes of Health: Heart, Lung, and Blood Institute

2012-2014: Program Chair- Annual Conference, National Association for Medical Direction of

Respiratory Care (NAMDRC)

2012 Committee member for the North America effort World Spirometry Day- in conjunction

with the 2012 Summer Olympic Games and ATS/ERS/European Lung Foundation

6-6-2013: 56th

Thomas L. Petty Aspen Lung Conference: The Lung Microbiome: A New Frontier in

Pulmonary Medicine. Moderator of State of the Art Session - Mucosal Immunity and the

Microbiome.

2013-2014 Fibrosis Across Species Symposia – Planning Committee member, April 27-29. 2014,

Louisville, KY. Conference workshop bringing together a core of human and veterinarian

scientists and clinical practitioner experts in lung fibrosis in humans, dogs, cats, and

thoroughbreds (in which pulmonary fibrosis is similar)- to develop a comparative research

network and a Road Map for future basic and clinical research in fibrosis. In cooperation

with the Westie Foundation of America and hosted by the University of Louisville Medical

and Equine Centers, Louisville, KY.

2013-2015: President, National Association for Medical Direction of Respiratory Care (NAMDRC)

2015-2020: Chair, Health Quality Expert Committee, United States Pharmacopeia Society (U.S.P.)

2015-2020: United States Pharmacopeia Society (U.S.P.) Council of Experts Member

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2015-2017: Past President, National Association for Medical Direction of Respiratory Care

(NAMDRC)

D. International Service

2004- present: Board of Directors for The National Respiratory Training Center

2004- present: Member of the International COPD Coalition

E. Public Service

3/30/99: Press Conference for the University of Kentucky Multidisiplinary Lung Cancer Clinic

5/2/99: 27 HealthFirst Magazine with Jerry Sanders (Channel 27) - discussing “Lung

Cancer and the University of Kentucky Multidisiplinary Lung Cancer Clinic”

7/10/99: National Public Radio WEKU 88.9FM Interview with Stu Johnson regarding “Lung

CT scanning and its utilization in early detection of lung cancer (Lancet article

critique)”

8/29/99: Lexington Herald-Leader interview and article: “Asthma Reaching Epidemic

Proportions: Kentucky’s Asthma Rate on Par with Rest of U.S.”

9/99: National Media Tour in New York City, Chicago, and Los Angeles to raise public

awareness of Chronic Obstructive Lung Disease (COPD) via media coverage and a video

news release (VNR). National spokesperson was Loni Anderson with Dr. Doherty as the

medical expert. Objective was to raise public awareness of COPD. Ms Anderson’s parents

were afflicted early in life with COPD. Media included: a video news release (VNR). 29

live radio interviews, 11 television interviews, 6 print/wire news media interviews

including FOX News (national), Good Day New York, WGN-TV news (national),

WWOR-TV News (national), CNN Radio (national), WOR-NY, KNX-LA KIIS-Boston,

New York Post, New York Times, Chicago Sun-Times, LA Times.

10/12/99: Satellite Media Tour- Live TV interviews with 27 TV news programs across the US.

“COPD Public Service Announcement (PSA) sponsored by NLHEP (National Lung

Health Education Program)”.

11/15/99: Associated Press interview: “Forest rage on in Eastern KY: Effect(s) on resident’s and

firefighter’s respiratory status”. Carried by newspapers across the U.S. via the AP wire.

11/16/99: WLEX-TV news story interview. “Effects of forest fire smoke in Eastern KY on the

respiratory status of residents and firefighters.”

11/22/99: Channel 27 interview with Jerry Sanders (medical reporter) - “COPD Awareness-

Spirometry: Testing Your Lungs and Knowing Your Numbers”

12/6/99: WLEX-TV Channel 18 Noontime Interview- “New Year’s Resolution”. 10 minute TV

interview with Nancy Cox on COPD, smoking, and smoking cessation.

3/12/00: Lexington Herald-Leader Newspaper interview and article: “Kentucky can’t put down its

cigarettes”

4/11/00: Web MD: Internal Medicine News- “Office Spirometry to Detect Early COPD

Encouraged- Individual Signs, Symptoms Often Inaccurate in Identifying Airway

Disease.”

9/10/00: National Media Tour for COPD Public Awareness campaign of the National Lung Health

Education Program (NLHEP), in Miami, Dallas, Cincinnati, San Francisco, and Phoenix to

raise public awareness of Chronic Obstructive Pulmonary Disease (COPD) and ‘Early

Detection of COPD with Spirometry” via media coverage of most major radio and TV

stations in these cities. National spokesperson was Loni Anderson with Dr. Doherty as the

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medical expert. Ms. Anderson’s parents were afflicted early in life with COPD. A

presentation of smoking prevention and cessation data to a high school in Cincinnati (St.

Xavier H.S.) was done where the ‘Key to the City of Cincinnati’ was presented to Dr.

Doherty and Ms. Anderson. Dr. Doherty gave the opening ceremonies/Keynote address to

the American Association of Respiratory Care National Convention in Cincinnati.

11/2/00: Channel 27 news with Jerry Sanders (medical reporter). “Effects of Eastern Kentucky

forest fires on Lexington and Eastern Kentucky health status with respect to the lungs.”

11/2/00: Channel 18 WLEX-TV with Lisa Kaplan (medical reporter) - “Effects of Eastern

Kentucky forest fires on Lexington and Eastern Kentucky health status with respect to the

lungs.”

11/3/00: Lexington Herald-Leader front page article (John Cheez): “Effects of Eastern

Kentucky forest fires on Lexington and Eastern Kentucky health status with respect to the

lungs.”

3/2/01: Channel 18 WLEX-TV with Lisa Kaplan (medical reporter) - “Health Watch Report:

Chronic Obstructive Lung Disease (COPD) or Smoker’s Lung.”

3/22/01: Interview for Kentucky Living Magazine for article “COPD Takes Your Breath

Away” by Vikki Franklin, June 2001 issue.

4/17/01: Channel 18 WLEX-TV ‘Let’s Do Lunch’ with Lisa Kaplan - “Chronic Obstructive

Lung Disease: Test Your Lungs, Know Your Numbers- Early Identification”

5/1 - 2/01: National Media Tour for COPD Public Awareness campaign of the National Lung Health

Education Program (NLHEP), Chicago, IL. Media coverage was by TV, Radio, and

newspapers. Robert Klein as spokesperson as a patient with chronic bronchitis with Dr.

Doherty as medical expert and Co-Chairman of the NLHEP. Media interviews included

WGN Radio, WFLD-TV, WCKG-FM radio, WSCR Radio, Fox-TV, WGN-TV, WMAQ-

TV, WLS-TV, and the Chicago Tribune and Chicago Sun-Times newspapers.

6/4/01: Radio interview on Chronic Obstructive Lung Disease (COPD) by Kathy Johnson,

University of Kentucky Public relations, for distribution to air on 90 radio stations

throughout Kentucky

10/2 - 4/01: National Media Tour for COPD Public Awareness and ‘Women and COPD’ campaign of

the National Lung Health Education Program (NLHEP), Atlanta, GA. Media coverage was

by TV, Radio, and newspapers. Loni Anderson was the national spokesperson with Dr.

Doherty as the medical expert and Co-Chairman of the NLHEP. Media interviews included

WXIA-TV, WSB TV, WAGA-TV, WGCL-TV, CNN-Radio Network, WSTR-FM, The

Zone (790-AM), WGST-AM, WMVX-FM, WKLS-FM, WDCO-FM, WFOX-FM.

10/16/01: National Lung Health Education Program Briefings on Chronic Obstructive Pulmonary

Disease (COPD) in Chicago, IL. Live interview on WGN-Radio, taped interview on

WBBM Radio on COPD, and interviews with healthcare reporters from TV stations:

WBBM-TV, WLS-TV, WFLD-TV.

10/16/01: Anthrax as it affects the community live interview live on WGN-Radio and a taped

interview on WBBM Radio, Chicago, IL.

10/18/01: Anthrax: It’s impact on the community, heightened awareness, and the signs, symptoms

and presentation of the disease. Jerry Sander’s, Health Reporter, Channel 27-TV,

Lexington, KY

10/22-23/01: Inhalation Anthrax (Woolsorter’s Disease), Jerry Sander’s, Health Reporter, Channel 27-

TV, Lexington, KY

10/23/01: Asthma: It’s Diagnosis and Treatment, WVLK-Radio interview with Anthony Ridgeway.

Distributed to five radio stations in the Lexington listening area.

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11/3 - 9/01: National Media Tour for COPD Public Awareness and ‘Women in COPD’ campaign of the

National Lung Health Education Program (NLHEP), Philadelphia, PA and New York City,

NY. Media coverage by TV, Radio, and newspapers. Loni Anderson was the national

spokesperson with Dr. Doherty as the medical expert and Co-Chairman of the NLHEP.

Media interviews included ABC-Philadelphia affiliate, KYW-TV, Pure Oxygen Network

News, WPIX-TV, WHAT-AM, KWY-AM, WSYP-FM, WNNJ-Radio, WOR-Radio,

Bloomberg Radio, Alberta Lung Association Second Wind Magazine, NY Stock Exchange

meeting with CEO and President who promoted COPD Awareness at NYSE.

10/01: 27 United States Governors declare October 2001 as COPD Awareness month in their

states (See text below 11/13/01)

11/13/01: President Bush announces Presidential Proclamation of November, 2001 as “National

COPD Awareness Month’. This began with Dr. Dennis Doherty and Dr. Thomas Petty, Co-Chairman

of the National Lung Health Education Program (NLHEP) and Sam Giordano, Executive Director of the

American Association of Respiratory Care (AARC) to petition the U.S. House of Representatives to declare

October as National COPD Awareness Month to help raise public awareness of COPD. This was well

received to the point that on July 25, 2001 Congressman Cliff Stearns (R-FL) and John Lewis (D-GA), in a

bipartisan fashion, introduced House Concurrent resolution 197, a resolution that would designate October as

COPD awareness month. In anticipation of this we also asked President Bush to join this effort with a

Presidential Proclamation. Several leaders of other organizations/societies (AARC, ATS, ALA, ACCP,

NAMDRC, NMA, NEF) joined this coalition and signed a letter sent to President Bush July 24, 2001. Due to

the tragic events of Sept 11 we asked the President and Congress to forestall the effort until next year in light

of other issues facing our nation. The support was so strong however, that 23 individual states had already

declared October as COPD month and we were called and asked by the White House to consider having a

Presidential Proclamation to declare November as National COPD Awareness Month. This came to fruition

on November 13, 2001

11/15/01: Satellite Media Tour- Live TV interviews with 17 TV news programs across the US and

one Radio news station: “Women and COPD Public Service Announcement (PSA) in

conjunction with the national ‘Great American Smoke Out’ day. Sponsored by NLHEP

(National Lung Health Education Program)”.

1/15 - 16/02: National Media Tour for COPD Public Awareness and ‘Women in COPD’ campaign of the

National Lung Health Education Program (NLHEP) Minneapolis/St. Paul, MN. Media

coverage by TV, Radio, and newspapers. Loni Anderson was the national spokesperson

with Dr. Doherty as the medical expert and Co-Chairman of the NLHEP. A presention of

smoking prevention and cessation data to a high school in St. Paul (Harding H.S.) was done

where a ‘Certificate of Recognition from the state of MN and city of St. paul for Public

Service in COPD Awareness’ was presented to by Mayor Randy Kelly and Governor Jesse

Ventura to Dr. Doherty and Ms. Anderson. Media interviews included KSTP-TV, WCCO-

TV, KMSP-TV, KARE-TV, and the following radio stations; KDWB, WCCO (2

programs), KTCZ, KQRS, and an interview with the Star Tribune newspaper.

8/27/02: Channel 18 WLEX-TV ‘Healthy Airways’ with Lisa Kaplan - “Asthma Diagnosis and

Management”

8/31/02: Newsday/The Journal News, New York - interview on COPD with reporter Ian D’Giff

10/9/02: United States Congressional Briefing on Chronic Obstructive Lung Disease (COPD). Dr.

Doherty presented a physician’s perspective on raising public awareness of COPD to

members of the U.S. Senate and U.S. House of Representatives in Washington, D.C.

11/18/02: Channel 18 WLEX-TV “Let’s Do Lunch: Gender and COPD and World COPD Awareness

Day” with Lisa Kaplan

12/16/02: Channel 18 WLEX-TV “COPD – Early Signs for Early Detection” with Lisa Kaplan

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2/3/03: NBC Year in Review: Medical Issues in 2002 that were presented to Congressional

Committees. Dr. Doherty spoke on the rising morbidity and mortality of COPD in the U.S.

4/25/03: Senior’s Health Fair, Hollywood, FL. Main stage talk with Loni Anderson on Chronic

Obstructive Pulmonary Disease and supervising respiratory therapists at a Spirometry

Early-Detection Workstation. Also conducted a seminar with seniors, with and without

diagnosed COPD to answer their questions and give advise regarding COPD.

5/2/03: Interview with Aging with Style Magazine – “Living with COPD: Early Diagnosis and

Management” editor: Peggy Austin. Coverage of the above event- with more details- for

publication in next issue of magazine.

August 2003: Public Awareness commercial ran 4-5 times per day every day in August on Channel 27,

WKYT-TV in Lexington, KY. Content was designed to raise public awareness of asthma,

its clinical presentation and treatment, as well as to make public aware of the asthma

clinical program - “Healthy Airways’- designed for prevention and management of asthma

within the KY healthcare network of CHA. Aired via Channel 27 ‘Health Check’ Program

11-10-03: Interview with UPI (United Press International) newswire service on COPD and the first

National COPD Awareness Conference in Arlington, Virginia Nov 14-15, 2003.

Interviewed because I was Co-Chair of the Planning Committee for the meeting and the

Co-Chair of the National Lung Health Education Program

November 2003: Public Awareness commercial ran 4-5 times per day every day in November on Channel

27, WKYT-TV in Lexington, KY. Content was designed to raise public awareness of

COPD, its prevalence, climbing death rate, clinical presentation and treatment, as well as to

make public aware of the COPD clinical program - “Healthy Airways’- designed for

prevention and management of COPD within the KY healthcare network of CHA. Aired

via Channel 27 ‘Health Check’ Program (ran intermittently through 2004)

August 25, 2004: Interview for an article in Physician Practice magazine on COPD and the opening of the

new UK COPD Clinic

August 26, 2004: Filmed 12 min DVD on The Ill Effects of Smoking- targeted toward Kentucky’s 7th

and 8th

grade students – Supported by a grant from the Centers of Disease Control (CDC) via the

Kentucky School of Osteopathic Medicine in Pikevillle, KY.

August 27 2004: Public Service Announcement on WEKU-National Public Radio network with Stuart

Johnson with regard to COPD and introduction of the new UK COPD Clinic.

January 24, 2005: Interviewed for article which ran in the Atlanta Constitution Journal - a story that appeared

there and in the National media on COPD – in conjunction with a story on Johnny Carson’s

death from ‘emphysema’.

January 29, 2005: Submitted photos to NIH, NHLBI of performance of office spirometry (doctor and patient)

for use in COPD Educational materials to be distributed nationwide

January 31, 2005: Channel 18 WLEX-TV Medical news at 5PM “Long-term Oxygen Therapy: New and

Novel Portable Devices” with Lisa Kaplan

January 31, 2006: COPD Awareness Satellite Media Tour from New York City – discussed COPD live with

13 TV stations and 6 radio stations across the U.S. – accompanied on the air by a COPD

patient

March 3rd

-4th

, 2006: Chaired an Employee health roundtable discussion to optimize the recognition and

management of COPD in the Workplace. Medical directors from these major corporations

present: Coca Cola, Verizon, Delphi, Eastman Kodak, Waste Management Inc, Texas

Instruments, Lockheed martin, Gillette (after acquisition by Procter and Gamble), Navistar

June 7th

-8th

, 2006: Represented the National Association for the Medical Direction of Respiratory Care

(NAMDRC) at a Summit on Oxygen Therapy – to discuss the effects of the U.S. Deficit

Revised 7/1/16


Reduction Act (DRA) on patient ownership and reimbursement for long-term oxygen

therapy (LTOT) at American College of Chest Physician Headquarters, Northbrook, IL

October 24, 2006: Sat on a panel discussing Long-Term Oxygen Therapy at the U.S. COPD Coalition

Meeting in Salt Lake City, Utah and presented the status of Oxygen Therapy Research

October 27, 2006: Interviewed by Consumer Reports on Health magazine for an article on Spirometry testing

and COPD – Joel Keehn. Contributing editor

November 1, 2006: WUKY – Guest on Health Matters Weekly show with Dr. Tony Weaver as host. Live radio

show on which in a round table format we discussed lung health in general, as well as

specifically COPD, long-term oxygen therapy, clinical and basic research in the pulmonary

field, and current events in the healthcare arena.

February, 2010 Drive4COPD COPD Awareness Campaign- Raising public awareness about COPD and

earlier detection via the use of a COPD screener questionnaire with Patty Loveless, country

singer- in Atlanta, GA and Nashville, TN

November 18, 2013: Satellite Media Tour- Live TV interviews with 28 TV and radio news programs across the

United States: “COPD and the Role of Caregivers” in conjunction with National COPD

Awareness Month and Family Caregiver Month. Sponsored by the COPD Foundation.

VII. REVIEW AND REFEREE ACTIVITIES

Editorial Board:

1995-present: Pulmonary Reviews (Editorial Board)

1997-present: BreathWell (Editorial Board)

1998-2003: Airwaves Pulmonary Internet Site for Patients (Editorial Director)

1999-2005: The Journal of COPD Management (Editorial Director)

2003-present Medical Editor for American Lung Association web-based COPD Profiler (Patient Site)

2003-present Medical editor for International Guidelines for the Management of COPD

2005-present Journal of Organ Dysfunction (international journal published in China)

2006-present International Journal of Chronic Obstructive Lung Disease

Ad hoc reviewer for the following journals (date listed to present):

1991-present: American Journal of Pathology

1991-present: American Journal of Respiratory Cell and Molecular Biology

1988-present: American Journal of Respiratory and Critical Care Medicine

1988-present: Experimental Lung Research

1988-present: Infection and Immunity

1990-present: Journal of Applied Physiology

1989-present: Journal of Clinical Investigation

1989-present: Journal of Leukocyte Biology

1989-present: Pediatric Pulmonary

1993-present: NIH, NHL&B Institute grant review committee (PPG site visits/RFAs)

1994-present: External reviewer for VA Merit Review Grants Board for Respiration

1995-present: Journal of Immunology

2003-present: Journal of American Medical Directors Association (JAMDA)

2004-present: Journal of COPD

2005-present: Respiratory Care

VIII. TEACHING ACTIVITIES

Revised 7/1/16


A. Course Director/Courses:

1985-86: Pulmonary Research in Progress Lecture Series at National Jewish Center for

Immunology and Respiratory Medicine (Pulmonary & Critical Care fellows)

2000-2001: Veterans Administration Hospital Medical Residents Morning Report (attending)

B. Graduate and Medical School Lectures:

1986-1992: Sophomore Physical Diagnosis of the Lung

1988: Sophomore Introduction to Clinical Medicine Basic Physical Exam

1990-1995: Intensive Care Lectures for Internal Medicine Houseofficers at Denver VAMC

1986-present: Pulmonary Consults and General Medicine Attending at Denver and Lexington VAMC

1993-1995: Pulmonary Lecture Series for Pulmonary Fellows- Use of Anticholinergics in COPD

1995: Pathology Lecture (Unit II Alternative Pathology): Monocytes/Macrophages and the

Lung

1996-1998: Introduction to the Medical Profession (MD 821-Sophomore Physical Diagnosis

4/15/97: Internal Medicine Noon Conference Series: Interstitial Lung Disease

5/15/97: UK 'Fireside Chat' for KY Telecare Network: Interstitial Lung Disease

12/3/97: Medical Grand Rounds University of Kentucky Dept of Internal Medicine

1998-1999: Medicine/Surgery Medical Student Clerkship (MD836)

11/16/98: Family Practice Noon Conference, University of Kentucky Medical Center

6/24/04: Journal Club- UK Dept of family Practice: Review of COPD- lecture and article review

C. Medical Student Preceptor:

1989-90 - Lorraine Golosow 1990-91 - Michelle Felton 1992-93 - John Baer

1992-93 - Michael Stackpool 1993-94 - Richard Cooper

D. Graduate Student Thesis Advisor/Internal Medicine Resident Advisor:

1993-95 - Paul Wolters (pulmonary fellowship-University of California, San Francisco)

1995-97 - Chalon Majewski-Tiedeken (Masters Program in Biology)

E. Postdoctoral Research Fellows:

1988-1991: Nobuyuki Hirose, M.D., Kyushu University Faculty of Medicine, Fukuoka, Japan

7/91-6/93: Talat Z. Khan, M.D., Pediatrics pulmonary fellow, Denver Children's Hospital

3/92-4/94: Junichi Nakano, M.D., Department of Medicine and Physical Therapy, University of

Tokyo School of Medicine, Tokyo, Japan

3/92-4/94: Keiko Nakano, M.D., Department of Radiology, Tokyo Women's Medical College,

Tokyo, Japan

7/93-6/94: Eugene Sullivan, M.D., Department of Medicine, Division of Pulmonary and

Critical Care Medicine, University of Colorado Health Sciences Center

3/94-8/97: Masashi Desaki, M.D., Department of Medicine and Physical Therapy, University

of Tokyo School of Medicine, Tokyo, Japan

8/96-6/97: Michael I. Anstead, M.D. Division of Pulmonary and Critical Care Medicine 3rd

year of Clinical and Research Fellowship, University of Kentucky Medical Center

7/97-6/00: Ketan Buch, M.D., Clinical Fellow, Division of Pulmonary and Critical

Care Medicine, University of Kentucky Medical Center

7/99-6/02t: Sanjiv Patel, M.D., Clinical Fellow, Division of Pulmonary and Critical


Revised 7/1/16


7/00-6/02: Kevin Lewis, M.D., Clinical Fellow, Division of Pulmonary and Critical


7/00-6/03 Karl Boethel, M.D., Clinical Fellow, Division of Pulmonary and Critical


7/00-6/03: John Kudlak, D.O., Clinical Fellow, Division of Pulmonary and Critical


7/01-6/04: David Atkins, M.D., Clinical Fellow, Division of Pulmonary and Critical


7/01-6/04: Wheeler Dale, M.D., Clinical Fellow, Division of Pulmonary and Critical


7/02-6/05: Michael Zgoda, M.D., Clinical Fellow, Division of Pulmonary and Critical


7/02-6/05: Davis Hiestand, M.D., Clinical Fellow, Division of Pulmonary and Critical


7/03-6/06: Katarina Slynokova, MD, Clinical Fellow, Division of Pulmonary and Critical


7/03-6/06: Adnan Habib, MD, Clinical Fellow, Division of Pulmonary and Critical


7/04-6/07: David Hasselbacher, MD, Clinical Fellow, Division of Pulmonary and Critical

Care, and Sleep Medicine, University of Kentucky Medical Center

7/04-6/07: Simit Bhullar, DO, Clinical Fellow, Division of Pulmonary and Critical


7/05-6/08: Matthew Reichert, MD, Clinical Fellow, Division of Pulmonary and Critical


7/05-6/08: Eric Weaver, MD, Clinical Fellow, Division of Pulmonary and Critical


7/06- 6/09: Andrea Johnston, MD, Clinical Fellow, Division of Pulmonary and Critical


7/06– 6/09: Elias Kakish, MD, Clinical Fellow, Division of Pulmonary and Critical


7/07- 6/10: Joel Niebuhr, MD, Clinical Fellow, Division of Pulmonary and Critical


7/07- 6/10: Arthi Thangaraj, MD, Clinical Fellow, Division of Pulmonary and Critical


F. Junior Faculty Research Mentor:

8/96-4/00: Peter E. Morris, M.D., Assistant Professor of Medicine, Division of Pulmonary and

Critical Care Medicine, University of Kentucky Medical Center

7/97-2001: Michael I. Anstead, M.D., Assistant Professor of Medicine, Division of Adult

Pulmonary and Critical Care Medicine, Division of Pediatric Pulmonary Medicine,

University of Kentucky Medical Center

4/98-present: Eric S. Bensadoun, M.D., Associate Professor of Medicine, Division of Pulmonary

and Critical Care Medicine, University of Kentucky Medical Center

7/98-present: Edward A. Hirschowitz, M.D., Associate Professor of Medicine, Division of

Pulmonary, Critical Care, and Sleep Medicine, University of Kentucky Medical Center

7/98-6/00: Lance T Piecoro, Pharm.D., MSPH, Assistant Professor, College of Pharmacy,

University of Kentucky

Revised 7/1/16


7/00-present: Ketan Buch, M.D., Assistant Professor of Medicine, Division of Pulmonary,

Critical Care, and Sleep Medicine, University of Kentucky Medical Center

3/01-6/06 Margaret M. Love, PhD, Assistant Professor Department of Family Practice, University of

Kentucky, serve as Dr. Love’s mentor on an asthma project- NIH Career Training in

Therapeutics and Translational Research (K-30)

7/05-7/06: Michael Zgoda, MD., ., Assistant Professor of Medicine, Division of Pulmonary, Critical


7/05-12/07: David Hiestand, MD, PhD., Assistant Professor of Medicine, Division of Pulmonary,

Critical Care, and Sleep Medicine, University of Kentucky Medical Center

7/09-12/12: Enrique Guzman-Diaz-Zavala, MD, Assistant Professor of Medicine, Division of

Pulmonary, Critical Care, and Sleep Medicine, University of Kentucky Medical Center

9/12-11/13: John Pospisil, PhD, MPH Patient Safety Fellow, Lexington VAMC

G. Visiting Professorships:

International Visiting Professorships:

2/16/96: Regional Conference on Lung Injury and Repair, sponsored by Teikyo University,

Tokyo, Japan: "Mechanisms of Monocyte Accumulation in the Lungs"

2/17/96: "Etiology and Treatment of Idiopathic Interstitial Pneumonitis Conference, hosted by

Hiroshima University, Hiroshima, Japan: "A New Therapeutic Intervention to

Prevent Neutrophil and Monocyte Accumulation in the Lungs: rBPI21"

2/19/96: Visiting Professor at Kyoto University, Kyoto, Japan: "Differential Diagnosis and

Treatment of Interstitial Lung Disease"

2/20/96: Visiting Professor at the International Medical Center, Tokyo, Japan: "Differential

Diagnosis and Treatment of Asthma, COPD, and Rhinitis"

2/22/96: Visiting Professor at Tokyo Women's Medical College, Tokyo, Japan: "Differential

Diagnosis and Treatment of Interstitial Lung Disease"

7/21-25/98: Quito Medical Conference, sponsored by The Catholic University, Quito,

Ecuador and University of Kentucky Medical Center, Office of CME

"High Altitude Pulmonary Edema and Acute Mountain Sickness"

"Differential Diagnosis and Management of Asthma, Chronic Bronchitis,

Emphysema" "Differential Diagnosis of Interstitial Lung Disease: Idiopathic

Pulmonary Fibrosis (IPF)

9/9/98: Visiting Professor at University of Toronto Department of Respirology, Toronto,

Ontario, Canada: Research Seminar- "ICAM-1 and Pulmonary Fibrosis"

9/10/98: Visiting Professor at McMaster University and Medical Center and the Firestone

Respiratory Clinic, Hamilton, Ontario, Canada : Research Seminar "ICAM-1 and

Pulmonary Fibrosis"

9/11/98: Great Lakes Lung Conference, Niagara-on-the-Lake, Ontario, Canada

9/98: Zhong Shan Hospital and Shanghai Medical University, Shanghai, China

Co-Chairman (USA). Opening ceremonies presentation and additional talks:

"Differential Diagnosis and Management of Obstructive Lung Diseases"

9/13 – 16/06 Chiba Institute of Science, Chosie City, Japan. Plenary lecture at the Fifth International

Symposium on Scale Modeling – “Monocyte Lung Retention During Normal Conditions

and During Endotoxemia”

Revised 7/1/16


11/16-18/06: Co-Chaired Chronic Obstructive Pulmonary Disease session and delivered three talks at the

3rd

International Symposium on Respiratory Diseases/14th

Congress of the Asia Pacific

Association for Respiratory Care, Zhongshan Hospital, Fudan University, Shanghai, China

“The worldwide burden of COPD: Earlier detection and Management

“Assessing prognosis in patients with COPD”

“New strategies in the treatment of COPD”

11/3-5/07 3rd




“Long-term oxygen therapy: The science and the prescription. Implementation of the

recommendations of the 6th

Oxygen Consensus Conference”

11/7-9/08 4th




“COPD: Therapies for 2008-2009”, also Co-Chaired session “Novel Therapies for Chronic

Lung Diseases”

6/21-23/13 Malaysian Thoracic Society 2013 annual meeting, Kuala Lumpur, Malaysia: Delivered the

Plenary session - Controversies in COPD Trial Design: Can They Give Us The Right

Answers, and a lecture: Targeting Airway and Systemic Inflammation: Insights from the

Bench. Repeated the inflammation lecture for local chapters of the Malaysian Thoracic

Society in Kuching and Kota Kinabalu, Malaysia

12/3-5/15 Asian Pacific Respiratory Society (APRS) 2015 annual meeting, Kuala Lumpur, Malaysia:

Delivered two presentations: Tiotropium Respimat add-on therapy improves lung function,

as measured by peak expiratory flow, in adults across severities of symptomatic asthma, and

Once-daily tiotropium respimat add-on to at least ICS maintenance therapy reduces

exacerbation risk in patients with uncontrolled symptomatic asthma.

National Visiting Professorships:

8/30/89: Ohio State University Hospitals, Department of Medicine, Division of Pulmonary

and Critical Care Medicine, Columbus, Ohio

2/21/91: Maricopa Medical Center and Veteran's Admin. Hospital, Department of Medicine,

Phoenix, Arizona

3/28-29/91: Brooke Army Medical Center, Division of Pulmonary, Fort Sam Houston, TX

9/22-23/93: XOMA Corp, Division of Preclinical Studies, Berkeley, California

5/26/94: University Hospital, Division of Allergy and Immunology, Newark, New Jersey

10/20/94: Tripler Army Medical Hospital, Department of Medicine, Honolulu, Hawaii

4/20/95: Roseville Hospitals, Department of Medicine, Roseville, California

12/5/96: Sanai Samaritan Medical Center, Department of Medicine, Milwaukee, WI

2/28/97: Long Island Jewish Hospital, Department of Medicine, Long Island, NY

5/29/97: Altman Hospital, Department of Medicine, Canton, Ohio

11/21/97: Ferguson Memorial Lectureship, Bethany Medical Center, Kansas City, Missouri

5/11/98: University of Cincinnati, Division of Pulmonary and Critical Care Medicine

(Pulmonary Research Grand Rounds)

9/3/98: Medical College of Ohio, Department of Internal Medicine, Toledo, Ohio

10/14-15/98: Veterans Administration Medical Center Newark NJ System- East Orange VAMC,

East Orange, NJ and West Lyons VAMC, West Lyons, NJ

Revised 7/1/16


10/7-8/99: Ohio State University Hospitals, Department of Medicine (Medical Grand Rounds),

Division of Pulmonary and Critical Care Medicine (Pulmonary Research Grand Rounds),

Columbus, Ohio

9/25-26/00: Emory University, Department of Medicine (Medical Grand Rounds), Division of

Pulmonary and Critical Care Medicine (Pulmonary Grand Rounds), Atlanta, Georgia

11/9/00: Washington University School of Medicine (Pulmonary and Allergy Research Grand

Rounds), Divisions of Pulmonary and Critical care Medicine and Allergy and

Immunology, St. Louis, MO

10/9 – 10/01: University of Alabama-Birmingham, Department of Medicine (Medical Grand Rounds) and

Division of Pulmonary, Allergy, and Critical Care Medicine (Pulmonary Research Grand

Rounds), Birmingham, AL- talks and discussions on asthma.

1/23-24/02: University of Alabama-Birmingham, Department of Medicine (Medical Grand Rounds) and

Division of Pulmonary, Allergy, and Critical Care Medicine (Pulmonary Research Grand

Rounds), Birmingham, AL- talks and discussion on COPD.

2/15/02: Oklahoma State University Center for Health Sciences College of Osteopathic Medicine,

Tulsa, OK

3/20/02: TRIAD Cardiopulmonary Conference COPD lecture and Visiting professorship at Forsyth

Hospital Lung Center, Winston-Salem, NC

5-1-02: New York University School of Medicine: Research talk on role of ICAM-1 in pulmonary

fibrosis and resolution of inflammation in the lung

2/15-16/03: Oklahoma State University College of Osteopathic

Medicine, Tulsa, OK

12/17-18/03: Ohio State University Hospitals, Davis Heart and Lung Institute Lecturer, Columbus, OH

The role of LPS-binding proteins CD14, LBP, BPI23 in monocyte accumulation in the lung

under normal conditions and during endotoxemia

6/29/04: Medical University of South Carolina: New Directions in COPD lecture, faculty meetings

3/8/06: University of Cincinnati College of Medicine and Cincinnati Veterans Administration

Medical Center, Division of Pulmonary and Critical Care Medicine

4/19 – 21/06: North Shore-Long Island Jewish Health System, Manhasset, NY

9/9/10: Medical College of Toledo Division of Pulmonary and Critical Care Medicine

9/23/11: University of Tennessee at Memphis, Division of Pulmonary and Critical Care Medicine

National Convention Talks, Medical Grand Rounds, and Invited Keynote Addresses:

Chairman or Co-Chairman of National Conferences:

2006: American College of Chest Physicians PREP Courses at the University of Kentucky Chaired

and organized the 13 day long courses in Pulmonary, Cardiology, Neurology, and Urology

3/25-26/06: First Annual COPD Fellows Conference, American College of Chest Physicians, Tucson,

AZ – Chaired and Organized a conference for pulmonary fellows nominated by their

respective University fellowship programs for this comprehensive two day course on COPD

8/25 – 28/06: Co-Chaired and organized with Dr. Thomas L. Petty the Sixth Oxygen Consensus

11-15-10: Co-Chaired National Association for the Medical Direction of Respiratory Care

(NAMDRC) Oxygen Conference, Atlanta, GA

Revised 7/1/16


3/10 - 11/12: Fibrosis Across Organ Systems: A Road Map for Future Research, interdisciplinary

conference including experts in heart, kidney, liver, lung, and skin fibrosis, Program

Planning Committee, Denver, CO

3/22 - 24/12: Chaired NAMDRC 35th

Annual Meeting and Educational Conference, Cutting Edge

Science: Practical Applications for Your Pulmonary practice, Sonoma, CA

11-10-12: Co-Chaired Update on Biomarkers and Therapeutic Strategies in Airway Diseases at the

International Symposium on Respiratory Diseases-American Thoracic Society Annual

Meeting - Shanghai, China

3/21 -2 3/13: Chaired NAMDRC 36th

Annual Meeting and Educational Conference: Clinical,

Management and Healthcare Policy Issues in Pulmonary Medicine, San Diego, CA

4/8 - 4/10/13: Chaired Pulmonary Medicine Health Policy Summit- sponsored by NAMDRC, AARC,

ACCP, ATS, COPD Foundation, and NHOPA, Washington D.C.

6/5/13: Chaired session at the 56th

annual Thomas L. Petty Aspen Lung Conference - The Lung

Microbiome: A New Frontier in Pulmonary Medicine, Aspen, Colorado

Keynote Addresses and Plenary Sessions:

11/4/95: Keynote Speaker for 7th NPACE National Primary Care Nurse Practitioner's Convention

Boston, MA

11/8/96: 8th NPACE National Primary Care Nurse Practitioner's Convention, Boston, MA.

(Invited Speaker and Keynote Lecturer)

4/12/97: 1997 Kentucky Thoracic Society Scientific Conference Keynote on Lung Disease,

Lexington, KY

1/24/98: Taiwanese Medical Society of Northern Ohio Conference Keynote, Cleveland, Ohio

5/26/98: American Academy of Physicians Assistants Annual National Convention,

Differential Diagnosis and Management of COPD and Asthma in the Aging Population

Symposium, Symposium Chairman and Featured Speaker, Salt Lake City, UT

4/23/99: Distinguished Lectureship, American College of Physicians/American Society of

Internal Medicine Annual Conference:

Differential Diagnosis and Management of COPD: Recent Advances

3/24/00: Keynote Speaker: American Lung Association of Kentucky Annual Meeting,

Bowling Green, KY

10/7/00: Keynote Address/Opening Ceremony Lecture, American Association of Respiratory

Care National Convention, Cincinnati Ohio

6/14/01: Keynote Address; California Association of Respiratory Care Annual Conference,

Los Angeles, CA

5/23/03: ALA National Research Dinner @ ATS

9/18/03: American College of Osteopathic Internists Annual Conference Keynote Address, Montreal,

Canada

10/17/03: American Association of Cardiovascular and Pulmonary Rehabilitation Keynote Address,

Kansas City, MO

10/17/03: 63rd

Annual Convention and Scientific Sessions, Montreal, Quebec, Canada

2/7/04: University of South Carolina, School of Medicine, Columbia, SC 3rd

Annual

Geriatric Conference

4/22/04: American College of Physicians 2004 Annual Session, New Orleans, LA

6/15/04: American Academy of Nurse Practitioners, New Orleans, LA

Revised 7/1/16


6/16/04: 14th

Annual Conference-Case Management Society of America, Nashville, TN

6/17/04: Kentucky Osteopathic Medical Association Annual Meeting

6/23/04: Keynote Address/Robert Wood Johnson Medical School-Update in Obstructive Airway

Diseases

6/27/05: Opening Keynote address at the 1st World Congress Leadership Summit on Advances in

Treating and Managing The Cost of Respiratory Disease, Las Vegas, NV

6/27/05: Keynote Address at the World Congress Leadership Summit on Advances in Treating and

Managing the Cost of Respiratory Disease – State of Respiratory Disease in America

2006: Chaired and organized the American College of Chest Physicians PREP Courses at the

University of Kentucky (13 courses in Pulmonary, Cardiology, Neurology, and Urology)


AZ – Chaired and Organized this two day conference

9/13 – 16/06 Plenary lecture at the Fifth International Symposium on Scale Modeling – “Monocyte Lung

Retention During Normal Conditions and During Endotoxemia”

8/25 – 28/06: Co-Chaired and organized the Sixth Oxygen Consensus Conference, Denver, CO

Delivered talk on the History of Long-Term Oxygen Therapy

10/12/06: 3rd

Annual William Anderson, MD Memorial Lecture at the Annual American Lung

Association of Kentucky Conference: History of Oxygen Therapy: Recommendations of

the Sixth oxygen Consensus Conference

10/8/11: Thomas L Petty Moving Mountains Lung Health Conference, Denver, Colorado

6/15/13: Plenary Lecture for the annual Malaysian Thoracic Society Meeting in Kuala Lumpur,

Malaysia: Controversies in COPD Trial Design: Can They Give Us the Right Answers

11/11/15: Keynote lecture: Team-Based Care for Patients with COPD for a Regional COPD Care

Delivery Model Forum, Case Studies for Care Coordination Across the Continuum,

Highmark/BCBS, Pittsburgh, PA

Medical and Pulmonary Grand Rounds/National Society Annual Meeting Lectures:

9/21/89: Montana Medical Society, Helena, Montana and St. Peter's Hospital, Helena,

Montana

10/5/89: Rocky Mountain Drug Center "Western Region Symposium", Denver, Colorado

7/31/92: Colorado Academy of Physicians Assistants Annual Conf, Steamboat Springs, CO

5/5/93: Fitzsimmons Army Medical Center, Denver, Colorado

3/16/94: Denver Osteopathic Society, Denver, Colorado

5/26/94: Beth Israel Medical Center, Department of Medicine, Newark, New Jersey

6/3/94: Colorado Society of Respiratory Therapy Annual Meeting, Steamboat Springs, CO

10/7/94: Fort Carson Army Hospital, Department of Medicine, Colorado Springs, Colorado

11/9/94: East Orange Veteran’s Administration Medical Center, East Orange, New Jersey

12/2/94: St. Mary's Hospital, Dept of Family Practice, Milwaukee, Wisconsin

1/24/95: Wisconsin Pulmonary Medical Society, Milwaukee, Wisconsin

1/25/95: St. Joseph Hospital Medical Grand Rounds, Milwaukee, Wisconsin

6/1/95: American Association of Physician's Assistants National Meeting, Las Vegas, Nevada

7/26-27/95: University of Kentucky Medical Center, Department of Medicine

8/22/95: Tucson Veteran's Administration Medical Center, Respiratory Care Section

8/24/95: Good Samaritan Hospital Medical Grand Rounds, Phoenix, Arizona

9/95: Wayne State University, The Detroit Medical Center - September 5-6, 1995

Revised 7/1/16


10/10/95: Memorial Community Hospital Grand Rounds, Colorado Springs, Colorado

12/1/95: Portland Veteran's Administration Medical Center, Portland, Oregon

3/10-14/96: Fifth Annual Cardiovascular Disease in the High Risk Patient: An Interspecialty

Approach, Ohio State University Medical Center: High Altitude Pulmonary Edema,

and Diagnosis and Medical Management of Pulmonary Embolus, Snowmass, CO

4/25/96: Good Hall Hospital, Sanford, Maine

4/26/96: Lahey Clinic, Burlington, MA

5/7/96: Saint Mary's Hospital, Rochester, NY

5/8/96: University Hospital, SUNY Science Health Center, Syracuse, NY (Grand Rounds)

6/12/96: Luke Air Force Base Medical Hospital, Glendale, AZ (Grand Rounds)

7/17-19/96: Texas Society for Respiratory Care Convention, Dallas, Texas

8/16/96 Maricopa Research Foundation, Phoenix, AZ (Grand Rounds)

9/12/96: Nassau County Medical Center, East Meadow, NY

9/18/96 Clinical Updates in 1996 (invited Speaker). Mercy Hospital Med Ctr, Des Moines, IA

10/21/96: Wilcox Memorial Hospital, Lihue, Hawaii (Grand Rounds)

10/23/96: Kaiser Medical Foundation Medical Center, Oahu, Hawaii (Grand Rounds)

11/14-15/96: American Society of Consultant Pharmacists National Convention, Nashville, TN

(Invited Speaker)

11/16/96: Crucial Issues for the Primary Care Physician. Maricopa Health System CME,

Scottsdale, AZ. Mariegra Research Foundation (Invited Speaker)

11/26/96: Northern Kentucky Respiratory Society Meeting (Invited Speaker)

1/28/97: Columbia Rose Medical Center, Denver, CO (Grand Rounds)

2/14/97: National Primary Care Conference NPAC, Nurse Practitioners

Associates for Continuing Education, San Diego, CA (Invited Speaker)

2/15/97: Network for Continuing Medical Education Program, New York, NY (National

Broadcast).

2/23/97: Allegany County Medical Society, Pittsburgh, PA (Invited Speaker)

2/28/97: Southside Hospital, Long Island, NY (Grand Rounds)

3/8/97: Osteopathic Medical Foundation and Southwestern Conf. on Medicine, Tucson, AZ

University of Arizona, College of Medicine at Arizona Health Science Center,

Phoenix, AZ (Invited Speaker)

3/19/97: Cardondelet St. Mary’s Hospital, Tucson, Arizona (Grand Rounds)

4/4-5/97: NPACE National Primary Care Conference, Orlando, FL (Invited Speaker)

4/18/97: Holzer Medical Center, Gallipolis, OH (Grand Rounds)

5/15/97: Pulmonary Physiology and Pathophysiology Conference (Invited Speaker)

University of Louisville - 'Mechanisms of Monocyte Retention in the Lung'

(Invited Speaker)

5/21/97: American Society of Consultant Pharmacists, Phoenix, Arizona (Invited Speaker)

7/30/97: Pittsburgh Veteran's Administration Medical Center, Pittsburgh, PA (Grand Rounds)

8/19/97: Greater Louisville Allergy Society Conference, Louisville, KY (Invited Speaker)

8/20/97: Dayton Veteran's Administration Medical Center, Dayton, OH (Grand Rounds)

9/13/97: American Society of Consultant Pharmacists Pennsylvania State Chapter Annual

Conference, Baltimore, MD (Invited Speaker)

9/29/97: Salinas Valley Memorial Hospital, Salinas, CA (Grand Rounds)

10/22/97: The American Lung Association of Ohio's South Shore 8th Annual Conference,

Sawmill Creek, Ohio (Invited Speaker)

1/27/98: Columbia Rose Medical Center, University of Colorado Medical Center Affiliate,

Revised 7/1/16


Denver, Colorado (Grand Rounds)

2/11/98: Mt. Sinai Health Care System, Case Western Reserve University, School of

Medicine Affiliate, Cleveland, Ohio (Grand Rounds)

2/25/98: 29th Annual University of Kentucky Family Medicine Review, Lexington, Kentucky

(Invited Speaker)

3/19/97: Filipino Medical Society Quarterly Conference, Mesa, Arizona (Invited Speaker)

3/26/98: Franklin Square Hospital Department of Medicine, Baltimore, MD (Grand Rounds)

3/27/98: Washington Hospital Center, Dept. of Medicine, Washington, DC (Grand Rounds)

4/4/98: American College of Physicians Annual Conference, Recognition and Management

of Chronic Diseases in the Older Patient: Focus on COPD and BPH, Symposium

Chairman and Invited Speaker, San Diego, CA

4/28/98: 1998 American Lung Association/American Thoracic Society International

Conference, presentation of research abstract, Chicago, IL (Invited Presentation)

5/9/98: Somerset Kentucky Asthma Symposium, Somerset, KY (Invited Speaker)

5/17/98: American Society of Consulting Pharmacist's Annual National Convention, Orlando,

Florida (Invited Speaker)

6/3/98: 41st Annual Thomas L. Petty Aspen Lung Conference on Acute Lung Injury

(Invited presentation of research)

9/28/98: East Tennessee Department of Medicine, Holston Valley Hospital, Kingsport, TN

(Grand Rounds)

10/2/98: California Society of Respiratory Care and Society of Pulmonary and Critical Care

Medicine Annual Symposium, Sacramento, CA (Invited Speaker)

10/3/98: Phoenix Regional Medical Center, Primary Care Physician Symposium, Phoenix,

AZ (Invited Speaker)

10/10/98: Scioto County Medical Society Annual Meeting, Friendship, OH (Invited Speaker)

11/10/98: 10th NPACE National Primary Care Nurse Practitioner's Convention, Boston, MA.

(Invited Speaker )

11/13/98: American Society of Consulting Pharmacist's National Convention, Seattle, WA

(Invited Speaker)

3/19-20/99: Chairman, 1999 Annual Conference on Lung Disease, American Lung Association

of Kentucky and The Kentucky Thoracic Society

4/1/99: Nassau County Medical Center Medical Grand Rounds, E. Meadows, NY

4/22/99: American College of Physicians/American Society of Internal Medicine Annual

Conference: Diseases of the Aging Population in the New Millennium: Focus on

Hypertension, BPH, and COPD. Symposium Chairman and Speaker, San Diego, CA

9/10/99: Kaiser Permanente Medical Grand Rounds, Cleveland, OH

10/7/99: Ohio State Department of Internal Medicine Grand Rounds, Columbus Ohio

10/8/99: Ohio State Division of Pulmonary and Critical Care Medicine Pulmonary Grand

Rounds, Columbus, Ohio

3/15/00: Columbus Regional Hospital Medical Grand Rounds, Columbus, IN

4/6-9/00: 2000 Regional Respiratory Masters Conference on Asthma Management, Atlanta,

Georgia

4/13/00: Chairman and Moderator, Primary Care Symposium on COPD, HTN, BPH, and

Osteoarthritis, American College of Physicians/American Society of Internal

Medicine Annual Convention, Philadelphia, PA

6/1/00: 28th

Annual American Academy of Physicians Assistants Convention, Invited

Speaker, Chicago, IL

Revised 7/1/16


9/8/01: American Association of Respiratory Care COPD Symposium, Dallas, TX

12/12/00: St. Luke’s Hospital Medical Grand Rounds, Bethlehem, PA

4/20/01: Sacred Heart Hospital Medical Grand Rounds, Pensacola, FL

6/5/01: University of Cincinnati, Jewish Hospital, Medical Grand Rounds, Cincinnati, OH

8/3/01: Saint Joseph Hospital Medical Grand Rounds, Denver, CO

10/26/01: Fairview Hospital COPD Symposium, Cleveland, OH

12/20/02 Saint Michael’s Medical Center Medical Grand Rounds, Newark, NJ

1/23/02: Pulmonary Research Grand Rounds, University of Alabama-Birmingham

(ICAM-1 and Pulmonary Fibrosis)

1/24/02: Medical Grand Rounds, University of Alabama-Birmingham (Asthma)

3/22/02: American Medical Directors Association Annual Convention; COPD Symposium,

San Diego, CA

4/11/02: American College of Physicians/American Society of Internal Medicine COPD Symposium

(Speaker and Chairman), Philadelphia, PA

4/16/02: Kentucky Chapter of American College of Emergency Room Physicians, Lexington, KY

4/30/02: SUNY-Downstate Medical Center Medical Grand Rounds, Brooklyn, NY

5/1/02: Saint Luke’s Hospital Medical Grand Rounds, New York, NY

5/1/02: NYU Medical center Pulmonary Research Conference, New York, NY

5/10/02: 3rd

Annual Environmental Health Symposium, Sacred Heart Healthsystem, Pensacola, FL

5/15/02: American Thoracic Society 98th

Annual International Conference; Smoking and Asthma

Symposium, Atlanta GA

5/21/02: American Society for Consulting Pharmacists National Midyear Conference; COPD

Symposium, Las Vegas, NV

5/30/02: Sacred Heart Medical Center Medical Grand Rounds, Spokane, WA

5/31/02 University of Oregon Medical Center Pulmonary Grand Rounds, Portland, OR

6/14/02: Pulmonary Grand Rounds, University of Alabama-Birmingham (COPD)

6/21/02: Capital Healthcare Systems Medical Grand Rounds, Philadelphia, PA

7/11/02: Texas Academy of family Physicians Annual Meeting and Scientific Assembly: COPD and

Spirometry Workshop, San Antonio, TX

7/24/02: University of Kentucky Medical Grand Rounds (COPD)

7/25/02: Medical Directors of Blue Cross/Blue Shield Kansas, COPD Workshop, Kansas City, KS

8/2/02: Ohio Society for Respiratory Care Annual Meeting, Cleveland, OH

8/8/02: Southern Illinois University School of Medicine Medical Grand Rounds, Springfield, IL

9/4/02: Michigan State University- at Kalamazoo, Medical Grand Rounds, Kalamazoo, MI

9/20/02 Easton Hospital Medical Grand Rounds, Easton, PA

10/22/02: Saint Elizabeth’s Medical Center, Pulmonary Grand Rounds, Brighton, MA

10/31/02: University of California at Davis Medical Grand Rounds, Sacramento, CA

1/20/03: Texas Academy of Family Physicians

2003 Winter Symposium, Snowmass, CO Medical Grand Rounds

2/28/03: Spokane Society of Internal Medicine-Annual Scientific Mtg Grand Rounds,

Spokane, WA

3/4/03: San Joaquin General Hospital, Stockton, CA Medical Grand Rounds

3/11/03: Cox Medical Center & St. John’s Health System. Medical Grand Rounds, Springfield, MO

3/11/03: St. Johns Health Systems, Medical Grand Rounds, Springfield, MO

5/9/03: Franklin Square Hospital Medical Grand Rounds, Bolt, MD

6/4/03: Wayne State University/Detroit Medical center Medical Grand Rounds, Detroit, MI

6/25/03: Overton Brooks Veteran’s Administration Medical Center Grand Rounds, Shreveport, LA

Revised 7/1/16


9/3/03: New Jersey VAMC, Medical Grand Rounds, East Orange, NJ

9/3/03: St. Joseph’s Regional Medical Center, Medical Grand Rounds, Patterson, NJ

9/4/03: Overbrook Hospital Medical Grand Rounds, Newark, NJ

9/4/03: John F. Kennedy Medical Center Grand Rounds, Newark, NJ

9/5/03: St. Michael’s Medical Center Grand Rounds, Newark, NJ

9/26/03: Halifax Medical Center, Daytona Beach, FL Medical Grand Rounds

10/1/03: Columbia Presbyterian Medical Center Grand Rounds, New York, NY

10/1/03: Montefiore Medical Center Grand Rounds, New York, NY

10/2/03: St. Joseph’s Medical Center Grand Rounds, Yonkers, NY

10/8/03: Summa Health Systems Grand Rounds, Cleveland, OH

10/16/03: University of Kansas Pulmonary Grand Rounds, Kansas City, Kansas

10/31/03: ALA KY Pulmonary Care Symposium, Medical Grand Rounds, Lexington, KY

11/4/03: St. Mary Medical Center-Langhorne, PA, Medical Grand Rounds

11/19/03: Loma Linda University, Loma Linda, CA, Medical Grand Rounds

12/6/03: AARC 49th

International Respiratory Congress National Convention

Las Vegas, NV, Medical Grand Rounds

1/27/04: St. Vincent’s Hospital, Indianapolis, IN, Medical Grand Rounds

4/14/04: St. Joseph Medical Center, Medical Grand Rounds, Baltimore, MD

4/29/04: Swedish Hospital, Medical Grand Rounds, Seattle, WA

4/29/04: Overlake Hospital, Medical Grand Rounds, Bellevue, WA

5/28/04: Mt Sinai Hospital Medical grand Rounds, Baltimore, MD

6/16/04: Kaiser Permanente, Inglewood, CA

6/23/04: New Jersey VAMC Medical Grand Rounds, East Orange, NJ

6/29/04: Medical University of South Carolina Medical Grand Rounds, Charleston, SC

7/18/04: 2004 Texas Academy of Family Practice Annual Session, Woodlands, TX

7/21/04: Memorial Hospital Medical Grand Rounds, Jacksonville, FL

8/6/04: Saint Joseph Hospital Medical Grand Rounds, Denver, CO

8/19/04: Shady Grove Hospital Medical grand Rounds, Rockville, MD

8/18/04: Union Regional Hospital, Medical Grand Rounds, Monroe, NC

9/14/04: Shawnee Mission Medical Center, Medical Grand Rounds, Kansas City, KS

10/6/04: Wayne State University, Medical Grand Rounds, Detroit, MI

10/8/04: St. John Hospital Medical Grand Rounds, Detroit, MI

12/2/04: Mercy Hospital Medical Grand Rounds, Pittsburgh, PA

12/16/04: Einstein Medical Center Medical Grand Rounds, Philadelphia, PA

11/18/05: Hanover Hospital, Hanover, PA

11/16/05: American Lung Association of Kentucky Annual Symposium- invited lecturer- COPD

11/29/05: Halifax Medical Center, Daytona, FL

12/6/06: 51st Annual American Association of Respiratory Care (AARC) Respiratory Congress, San

Antonio, TX. National Lung Health Education program Seminar – Update on COPD

Management: What’s New

12/6/05: 51st Annual AARC Respiratory Congress, San Antonio, TX – Prognosis of COPD

1/4/06: National Naval Medical Center, Bethesda, MD

1/4/06: Georgetown University Hospital, Division of Pulmonary, Critical care, and Sleep Medicine,

Washington, DC

1/13/06: Banner Baywood Hospital, Mesa, AZ

1/26/06: Tripler Army Base Medical Center, Honolulu, Hawaii

1/25/06: Kuakini Medical Center, Honolulu, Hawaii

Revised 7/1/16


1/27/06: Queens Medical Center, Honolulu, Hawaii

1/28/06: Hilo Medical Center, Hilo, Hawaii

2/24/06: Southwest General Health Center, Department of Family Practice Grand Rounds, Cleveland,

OH

3/22/06: St. Mary’s Health System, Evansville, IN

3/22/06: Methodist Hospital, Henderson, KY

4/20/06: North Shore University Hospital, Manhasset, NY

4/21/06: Long Island Jewish Medical Center, Manhasset, NY

5/3/06: Department of Family Practice Grand Rounds, Memorial Hospital, York, PA

5/3/06: Lancaster General Hospital, Lancaster, PA

5/6/06: Pulmonary Medicine for Primary care practitioners – University of Cincinnati Division of

Pulmonary and Critical Care Medicine Conference, Cincinnati, OH

6/1/06: University of Illinois-Chicago, Division of Pulmonary and Critical care Medicine, Chicago,

IL

6/3/06: First Annual Pulmonary Symposium – Alexian Brothers Hospital network, Elk Grove, IL

9/6/06: 35th

Annual State Convention, South Carolina Society for Respiratory Care, Myrtle Beach,

SC

11/9/12: Targeting Airway and Systemic Inflammation of COPD- Insight from the Bench, at the

International Symposium on Respiratory Diseases-American Thoracic Society Annual

Meeting - Shanghai, China

4/12/13: Chronic Obstructive Pulmonary Disease (COPD) and Pulmonary rehabilitation, invited

faculty to the annual convention of the American College of Physicians, San Francisco, CA

10/28/13: Improvements in Lung Function with Tiotropium as Add-on Controller Therapy to

ICS+LABA for Patients with Symptomatic Severe Asthma. Oral presentation at the

American College of Chest Physician CHEST 2013 annual meeting, Chicago, IL.

5/28/14: Enhancing Chronic Obstructive Lung Disease (COPD) Management Across the Continuum

of Care. Medical Grand Rounds, Park Plaza Medical Center, Houston, TX.


of Care. Medical Grand Rounds, Shawnee Mission Medical Center, Shawnee, KS.


of Care. Medical Grand Rounds, Jackson Park Medical Center, Chicago, IL.


of Care. Medical Grand Rounds, The Medical Center of Central Georgia, Macon, GA.

7/14/14: Lung Function and COPD Exacerbations. Annual meeting of the American Medical

Directors Association (AMDA), Baltimore, MD

9/17/14: Lung Function and COPD Exacerbations. Annual meeting of the Gerontological Advanced

Practice Nurses Association (GAPNA), Orlando, FL.

H. National and State Medical Noon Conferences and Continuing Medical Education Programs

Topics: Differential Diagnosis and Management of Interstitial Lung Diseases

Differential Diagnosis and Management of Asthma, Chronic Bronchitis, and

Emphysema, Acute Mountain Sickness and High Altitude Pulmonary Edema

National Lectures:

5/10/89: Fitzsimmons Army Hospital, Denver, Colorado

9/22/89: Bozeman Deaconess Hospital, Bozeman, Montana

Revised 7/1/16


5/30/90: Valley View Hospital, Glenwood Springs, Colorado

6/11/90: Fort McPherson Hospital, Atlanta, Georgia

5/7/91: Gates Medical Clinic, Denver, Colorado

5/21/91: Veteran's Administration Medical Center, Phoenix, Arizona - May 1991

8/27/91: Detroit Osteopathic Hospital, Highland Park, Michigan

8/15/92: Wyoming Medical Center, Casper, Wyoming

2/3/92: Scottsdale Memorial Hospital, Scottsdale, Arizona

5/5/92: Avista Hospital, Louisville, Colorado

9/1/92: Garden City Osteopathic Hospital, Garden City, Michigan

3/1/93: Porter Hospital, Denver, Colorado

5/5/93: San Juan Regional Hospital, Farmington, New Mexico

10/22/93: University of Colorado Health Sciences Ctr Pulmonary Fellow Conf., Denver, CO

2/4/94: Community Hospital, Grand Junction, Colorado

4/19/94: Spokane Veteran's Administration Hospital, Spokane, Washington

4/19/94: Kootenai Memorial Hospital, Coeur D Alene, Idaho

5/6/94: Riddle Memorial Hospital, Media, Pennsylvania

5/16/94: Good Samaritan Hospital, Portland, Oregon

8/29/94: Saint Elizabeth's Hospital, Youngstown, Ohio

10/20/94: Straub Hospital, Honolulu, Hawaii

10/21/94: Honolulu Medical Group, Honolulu, Hawaii

4/19/95: Woodland Memorial Hospital, Woodland, California

6/16/95: Baylor College of Medicine- Pulmonary Section. Houston, Texas

8/22/95: St. Joseph's Hospital, Tucson, Arizona

8/23/95: Maricopa Medical Center, Phoenix, Arizona

8/30/95: St. Elizabeth's Hospital, Youngstown, Ohio

10/6/95: Evan's Army Medical Center, Colorado Springs, Colorado

11/2/95: Boston Veteran's Administration Medical Center, Boston, Massachusetts

11/3/95: Boston University Medical Center, Boston, Massachusetts

11/3/95: New England Medical Center, Boston, Massachusetts

11/28/95: Natividad Medical Center, Salinas, CA

11/29/95: Community Hospital, Monterey, CA

12/1/95: Salem Memorial Hospital, Salem, OR

1/18/96: Family Health Plan Asthma Implementation Team, Milwaukee, WI

4/17/96: Kalispell Regional Hospital, Kalispell, Montana

4/25/96: HMO Blue Asthma Task Force, Peabody, MA

4/29/96: Novato Community Hospital, Novato, CA

5/8/96: Saint Elizabeth's Hospital , Utica, NY

6/5/96 Maricopa Research Foundation-Continuing Education Primary Care Seminar,

Phoenix, AZ

8/28/96: Saint Elizabeth's Hospital Resident's Noon Conference, Youngstown, Ohio

9/18/96: Des Moines VA Medical Center, Des Moines, Iowa

10/16/96: Mathis Air Force Base, Sacramento, CA

4/15/97: University of Kentucky Medical Resident Noon Conference-Interstitial Lung

Disease

6/20/97: Michigan Capital Medical Center, Lansing, Michigan

8/28/97: St. Elizabeth's Hospital Resident's Noon Conference, Youngstown, Ohio

4/30/98: Vencor Hospital Medical Noon Conference, Arlington, Virginia

Revised 7/1/16


9/2/98: St. Elizabeth's Hospital, Youngstown, Ohio

11/24/98: Cincinnati Veterans Administration Noon Conference, Cincinnati, Ohio

6/12/99: Directors of Managed Care Pharmacies of Michigan Quarterly Conference, Cedar

Point, OH

9/9/99: 3rd

Annual Summer Symposium, St. Ann’s Hospital, Columbus, OH

9/16/99 Pulmonary Physiology and Medicine Symposium, St. Francis Hospital System,

invited speaker, Pittsburgh, PA

1/19/00: Scioto County Medical Society Annual Meeting, Portsmouth, OH

6/23-25/00: Primary Care Symposium, Southern Area Health Education Center, Pigeon Forge, TN

10/24/00: Connecticut Academy of Family Physicians Annual Meeting, Hartford, CT

11/9/00: St Louis University Department of Internal Medicine Noon Conference, St. Louis, MO

2/5/01: Cedars Sinai Resident’s Noon Conference, Los Angeles, CA

2/6/01: University of California Los Angeles Pulmonary Fellow’s Conference, Los Angeles, CA

2/6/01: University of California Los Angeles Resident’s Noon Conference, Los Angeles, CA

3/15/01: Allentown Veteran’s Administration Medical Center, noon conference, Allentown, PA

3/6/01: Idiopathic Pulmonary Fibrosis Update, Lexington, KY

3/27/01: Idiopathic Pulmonary Fibrosis Update, Louisville, KY

4/20/01: Sacred Heart Hospital, Medical Grand Rounds, Treatment of asthma as a disease of

inflammation, Pensacola, FL

5/9/01: Ball Memorial Hospital, Noon conference- Asthma diagnosis and treatment, Muncie, IN

6/5/01: Jewish Hospital, Noon conference- New modalities in COPD Treatment, Cincinnati, OH

8/3/01: Saint Joseph Hospital, Noon conference, COPD, Denver, CO

10/26/01: Fairfield Hospital Respiratory Conference, Early management of COPD, Cleveland, OH

12/20/01: Saint Michael’s Medical Center, Medical Grand Rounds, Newark, NJ

3/20/02: Senior Care Physicians Rounds on COPD at The American Medical Directors Association

Annual Convention, San Diego, CA

3/23/02: University of Kentucky CME: Diseases of the Senior Care Population- New directions and

the pharmacoeconomics of therapy for COPD in the Elderly, at The American Medical

Directors Association Annual Convention, San Diego, CA

4/11/02: University of Kentucky CME: Significant Lifestyle Changes Affecting the Elderly:

Overview of Therapies for COPD, at the American College of Physicians-American Society

of Internal Medicine Annual Convention, Philadelphia, PA

5-16-02: University of Kentucky CME: Betting on Breathing Easy: New directions in the diagnosis

and management of COPD at the American Society od Consultant Pharmacists 24th

Midyear

Conference, Las Vegas, NV

5-21-02: American Thoracic Society International Conference: Behind the Smoke Screen- the Untold

Story of Smoking and Asthma, Atlanta, GA

5/30/02: Third Annual Environmental Health Symposium, Tobacco and COPD, Sacred Heart

Hospital System, Pensacola, FL

6/14/02: Medical Resident’s Morning Report, University of Alabama-Birmingham, Department of

Medicine, Birmingham, AL

6/21/02: Capital Health Systems, noon conference, Trenton, NJ

7/11/02: Texas Academy of Family Physicians Annual Session and Scientific Assembly, COPD and

Office Spirometry Symposium, San Antonio, Texas

10/10/02: Elkin’s Park Hospital, Noon conference, Elkins park, PA

10/16/02: Speaker at the American Academy of Family Physicians Annual Conference on COPD, San

Diego, CA

Revised 7/1/16


10/22/02: Michigan State University at Kalamazoo Pulmonary Symposium, COPD, Kalamazoo, MI

10/30/02: Sacramento Valley Lung Club Annual Conference, New modalities in the treatment of

COPD, Sacramento, CA

12/10/02: American Society of Consulting Pharmacists Annual Convention, COPD Symposium,

Atlanta, GA

1/20/03: Texas Academy of Family Physicians Winter Symposium, 3 hour Workshop on COPD-

diagnosis to management, Snowmass, CO

2/29/03: Spokane Medical Society of Internal Medicine Annual Scientific Meeting, New directions in

COPD management, Spokane, WA

3/4/03: San Joaquin General Hospital, Noon conference, COPD, Stockton, CA

3/31/03: American Pharmaceutical Associations Annual Convention, COPD, New Orleans, LA

4/4/03: University of Kentucky CME: Uncovering Silent Killers in the Elderly- COPD, at the

American College of Physicians-American Society of Internal Medicine Annual

Convention, San Diego, CA.

6/16/03: Kaiser Permanent Noon Conference, Inglewood, CA

8/28/03: American Lung Association of Metropolitan Chicago special seminar: The National Lung

Health Education Program: Raising Awareness of the Public, Political Policymakers and

Healthcare Workers

9/9/03: Annual Meeting of ACP, Kentucky Chapter

Louisville, KY

9/27/03: Fall Medical Surgical Symposium-Lubbock-Crosby-Gaza County Medical Society,

Lubbock, TX

11/20/03: Minnesota Thoracic Society Physicians Forum

St. Paul, Minnesota

12/17/03: Center for Health Care Education, Cincinnati, OH

2/7/04: University of South Carolina 3rd

Annual Geriatric Symposium, COPD, Columbia, SC

4/21/04: American College of Physicians, New Orleans, LA

5/12/04: Pri Med West, Anaheim/LA, CA

5/15/04: 26th

Annual Midyear Conference American Society of Consultant Pharmacists, Improving

Lung Function:Evaluating New Options to Manage COPD, Phoenix, AZ

5/28/04: North Arundal Hospital Noon Conference, Baltimore, MD

7/20/04: Medical Staff Lecture for Memorial Hospital, Jacksonville, FL

7/30/04: Cleveland Allergy Society Monthly Conference, Cleveland, OH

8/1/04: 8th

Annual Summer Symposium, Mount Carmel St Ann’s Hospital, Columbus, OH

8/19/04: Suburban Hospital Noon Conference, Washington D.C.

9/15/04: Stormont Vail Hospital, Kansas City, KS

9/28/04: Annual Emergency Medical Association of New Jersey Conference, Atlantic City, NJ

9/30/04: Veterans Association Medical Center Noon Conference, Saginaw, MI

10/8/04: Bixby Hospital Noon Conference, Adrian, MI

10/29/04: 7th

Annual Respiratory Care Conference, Fairview Hospital, Cleveland, OH

11/9/04: University of California Los Angeles- Olive View Hospital Noon Conference

11/13/04: 98th

Annual Scientific Assemble of Southern Medical Association, Prevention, Detection,

and Management of COPD, New Orleans, LA

12/16/04: Jefferson Medical Center Pulmonary Noon Conference, Philadelphia, PA

12/17/04: The Chester County Hospital Noon Conference, Philadelphia, PA

1/18/05: 31st Annual Winter Symposium, Texas Academy of Family Physicians, Park City, UT

Revised 7/1/16


1/25/05: 6th

Annual Medicine in the New Millennium Symposium, Saint Francis Health Center,

Topeka, KS

1/28/05: St. Joseph Hospital Family Practice Conference, Denver, CO

2/9/05: NorthEast Medical Center Medical CME Update, Concord, NC

2/9/05: Presbyterian Hospital Internal Medicine Educational Conference Series, Charlotte, NC

2/10/05: Anthem Blue Cross Blue Shield Case Managers Conference, Mason, OH

4/6/05: Shaughnessy-Kaplan Rehabilitation Hospital’s Annual Pulmonary Rehabilitation

Conference, Salem, MA

4/19/05: 12th

Annual Illinois Case Managers Network Conference, Oakbrook Terrace, IL

5/5/05: Jenie Edmundson Hospital Noon Conference, Council Bluffs, IA

5/26/05: Balboa Navy Medical Center Pulmonary Conference, San Diego, CA

6/8/05: SUNY-Downstate Pulmonary Conference, Queens, NY

6/15/06: 48th

Annual Thomas L. Petty Aspen Lung Conference on COPD- abstract presentation on

the History of the NLHEP

7/16/05: Annenberg Center for Health Sciences and Eisenhower Medical Center- Essentials for the

Diagnosis and Management of COPD Symposium, Santa Monica, CA

9/22/05: Sacred heart Hospital, Reston, VA

9/25/05: 12th

Annual Pulmonary and Critical Care Symposium – Mercy Pulmonary Institute and

California Society of Respiratory Care, Sacramento, CA

10/1/05: Fairview Hospital-Cleveland Clinic Health System Annual Conference in Primary Care,

Cleveland, OH

10/8/05: 47th

Annual Ohio University College of Medicine Conference – invited lecturer on COPD

10/10/05: Community Hospitals and Wellness Centers Conference, Bryan, OH

10/10/05: Flower Hospital Medical Staff Meeting, Sylvania, OH - invited lecturer on COPD

10/12/06: Lakewood Hospital-Cleveland Clinic health System, Lakewood, OH

11/3/05: Kansas State Medical Education Annual Symposium, Topeka, KS

12/14/05: Delaware County Memorial Hospital, Drexel Hill, PA

1/13/06: Missions family Medical Center, Mesa, AZ

2/16/06: 2nd

Annual Winter Forum South Carolina Society for Respiratory Care, Charleston, SC

3/18/06: American Medical Director’s Association (AMDA) Annual Convention - invited lecturer -

Recognizing and Managing COPD in Long-term Care, Dallas, TX


AZ – Chaired and Organized the two day meeting and spoke on – The Burden of COPD

Local/State Lectures:

4/15/97: UK Medical Resident Noon Conference: Interstitial Lung Diseases

5/15/97: Fireside Chat Kentucky TeleCare Network: Interstitial Lung Diseases

12/3/97: University of Kentucky Department of Internal Medicine Grand Rounds

7/2/98: Clinical Research for the Year 2000 sponsored by KCCRIS, University of Kentucky

Invited Speaker: The Principal Investigator's Perspective: UHC and KCCRIS

interaction

11/16/98: Family Practice Noon Conference, University of Kentucky Medical Center

4/29/00: University of Kentucky CME Regional Symposium: Strategies for

Asthma Management; How severe is the patient, Lexington, KY

1/18/01: University of Kentucky Medical Resident Noon Conference: New Approaches to Managing

Idiopathic Pulmonary Fibrosis (IPF)

Revised 7/1/16


7/31/01: University of Kentucky Medical Resident Noon Conference: New Directions in the

Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease (COPD)

10/11/01: Kentucky Society for Respiratory Care Annual Symposium, Lexington, KY

3/12/02: Baptist Regional Medical Center, Corbin, KY

4/16/02: Kentucky Chapter of the American College of Emergency Physicians, COPD in the

emergency room setting, Lexington, KY

9/6/02: American Lung Association of Kentucky and the Kentucky Society for Respiratory Care

Annual Symposium, COPD Case studies, Bowling Green, KY

10/21/02: Hardin Memorial Hospital, Elizabethtown, KY

11/14/02: Highlands regional Medical center, Critical Care Symposium, Prestonsburg, KY

8/12/03: Internal Medicine residents Noon conference on COPD, University of Kentucky

8/18/03: Pulmonary and Critical Care Lecture Series, COPD and the GOLD Guidelines, UK

6/16/04: Medical Staff, London, KY

6/17/04: Kentucky Osteopathic Medical Association Annual Meeting, Elizabeth, IN

6/24/04: UK, Dept. of Family Practice Journal Club, Nicholasville, KY

8-20-04: Medical Grand Rounds, University of Kentucky, Update in Pulmonary and Critical Care

Medicine

8-23-04: Internal Medicine Residents Noon conference on COPD, University of Kentucky

8-8-05: Pulmonary and Critical Care – UK Fellows Lecture Series: COPD - Epi/Spiro/Smoking

8-15-05: Pulmonary and Critical Care – UK Fellows Lecture Series: COPD – Treatment

3-13-06: Internal Medicine Residents Noon Conference on Pulmonary Function Tests, University of

Kentucky

10-30-06: UK 38th

Annual Family Medicine Review Course, Current Care in COPD Part 1 and 2

12-5-06 Internal Medicine Residents Noon conference on PFTs, University of Kentucky

3-26-07 Pulmonary and Critical Care – UK Fellows Lecture Series: COPD - Epi/Spiro/Smoking

4-9-07 Pulmonary and Critical Care – UK Fellows Lecture Series: COPD – Treatment

IX. MANUSCRIPTS PUBLISHED AND SUBMITTED

Papers Published in Refereed Journals:

1) Doherty, D.E., and E. Neuwelt. 1977. Toxicity kinetics and clinical potential of subarachnoid lymphocyte

infusion. J. Neurosurg. 47:205-217.

2) Doherty, D.E., J. Falko, N. Lefkovitz, J. Rogers, and J. Fromkes. 1982. Pseudomonas Aeroginosa sepsis

following retrograde cholangiopancreatography (ERCP). J. Digestive Diseases and Sciences 27:169-170.

3) Doherty, D.E., and S. Schonfeld. 1983. Cholelithiasis in adult cystic fibrosis. Southern Med. J. 76:1580-1581.

4) Doherty, D.E., C. Haslett, M.G. Tonnesen, and P.M. Henson. 1987. Human Monocyte Adherence: A Primary

Effect Of Chemotactic Factors On The Monocyte To Stimulate Adherence To Human Endothelium. J.

Immunology 138:1762-1771.

Revised 7/1/16


5) Downey, G.P., R.S. Gumbay, D.E. Doherty, J.F. LaBrecque, J.E. Henson, P.M. Henson, and G.S. Worthen.

1988. Enhancement of Pulmonary Inflammation by PGE2: Evidence For A Vasodilator Effect. J. Appl. Physiol.

64(2):728-741.

6) Doherty, D.E., C. Haslett, G. Downey, G.S. Worthen, and P.M. Henson. 1988. Monocyte Retention and

Migration in Pulmonary Inflammation: Requirement for Neutrophils. Lab Invest 59(2):200-213.

7) Clark, R.A.F., N.E. Wickner, D.E. Doherty, and D.A. Norris. 1988. Cryptic Chemotactic Activity of

Fibronectin for Human Monocytes Resides In the 120kDa Fibroblastic Cell Binding Fragment. Journal of

Biological Chemistry 263:12115-12123.

8) Doherty, D.E., L. Zagarella, P.M. Henson, and G.S. Worthen. 1989. Lipopolysaccharide Stimulates

Monocyte Adherence By Effects On Both The Monocyte And The Endothelial Cell. J. Immunol. 143:3673-

3679.

9) Doerschuk, C.M., G.P. Downey, D.E. Doherty, D. English, R.P. Gie, M. Ohgami, G.S. Worthen, P.M.

Henson, and J.C. Hogg. 1990. Leukocyte and Platelet Margination Within The Microvasculature of Rabbit

Lungs. J. Appl. Phys. 68:1956-1961.

10) Doherty, D.E., P.M. Henson , and R.A.F. Clark. 1990. Fibronectin Fragments Containing the RGDS Cell-

Binding Domain Mediate Monocyte Migration Into the Rabbit Lung: A Mechanism for Neutrophil-Dependent

Monocyte Accumulation. J. Clin. Invest. 86:1065-1075.

11) Shaw, R.J., D.E. Doherty, A. Ritter, S.H. Benedict, and R.A.F. Clark. 1990. Adherence-Dependent Human

Monocyte PDGF(B) Gene Activation Is Associated With Increases In c-fos, c-jun, and EGR2 mRNA. J. Cell.

Biol. 111:2139-2148.

12) Downey, G.P., D.E. Doherty, B. Schwab, E. Elson, P.M. Henson, and G.S. Worthen. 1990. Retention of

Polymorphonuclear and Mononuclear Leukocytes in Model Capillaries in vitro and in the Pulmonary

Microvasculature of Rabbits: Role of Cell Size and Deformability. J. Appl. Phys. 69:1767-1778.

13) Doherty, D.E., H. Hirose, and R.M. Cherniack. 1992. Prolonged monocyte accumulation in the lung during

bleomycin-induced pulmonary fibrosis: Noninvasive assessment by external scintigraphy. Laboratory

Investigation 66:231-242.

14) Erzurum, S.C., G.P. Downey, D.E. Doherty, B. Schwab, E.L. Elson, and G.S. Worthen. 1992. Mechanisms

of Lipopolysaccharide-Induced Neutrophil Retention: Relative Contributions of Adhesive and Cellular

Mechanical Properties. J. Immunol. 149:154-162.

15) Fadok, V.A., J.S. Savill, C. Haslett, D.L. Bratton, D.E. Doherty, P.A. Campbell, and P.M. Henson. 1992.

Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to

recognize and remove apoptotic cells. Journal of Immunol. 149:4029-4035.

16) Hirose, N., D.A. Lynch, R.M. Cherniack, and D.E. Doherty. 1993. Correlation between high resolution

computed tomography and tissue morphometry in bleomycin-induced lung injury in the rabbit. American

Review of Respiratory Diseases 147:730-38.

Revised 7/1/16


17) Doherty, D.E., G.P. Downey, B. Schwab, E. Elson, and G.S. Worthen. 1994. Lipopolysaccharide-induced

monocyte retention in the lung: The role of monocyte stiffness, actin assembly, and adherence.

J. Immunol 153:241-255.

18) Bratton, D.L., Q. Hamid, M. Boguniewicz, D.E. Doherty, J.M. Kailey, and D.Y.M. Leung. 1995.

Granulocyte macrophage-colony stimulating factor contributes to enhanced monocyte survival in chronic atopic

dermatitis. J. Clinical Investigation 95:211-218.

19) Spahn, J.D., S.J. Szefler, W. Surs, D.E. Doherty, S.R. Nimmagadda, and D.Y.M. Leung. 1996. A novel

action of interleukin-13: Induction of diminished monocyte glucocorticoid receptor-binding affinity. J.

Immunol. 157:2654-2659.

20) Lynch, D.A., N. Hirose, R.M. Cherniack, and D.E. Doherty. 1997. Bleomycin-induced lung disease in an

animal model: Correlation between Computed Tomography-determined abnormalities and lung function. Acad

Radiol 4:102-107.

21) May, K.R., D.Y.M. Leung, J.M. Kailey, and D.E. Doherty, and D.L. Bratton. 1999. Staphylococcal Toxic

shock syndrome Toxin-1 inhibits monocyte apoptosis. J. Allergy Clin. Immunol. 103:895-900.

22) Sawyer, R.T., D.E. Doherty, B. Schumacher, and L.S. Newman. 1999. Beryllium-stimulated in vitro

migration of peripheral lymphocytes. Toxicology 138:155-163.

23) Hirschowitz, E.A., Weaver JD, Hidalgo GE, D.E. Doherty. 2000. Murine dendritic cells infected with

adenovirus vectors show signs of activation. Gene Therapy 7:1112-20.

24] Briggs, D.D., Kuritzky L., Boland, C., D.E. Doherty, Hedges, H., Levine, R., Pellegrino, K., Radin, A.M.,

Sahn, S.A. (The National COPD Awareness Panel). 2000. Keys to the early detection and management of

COPD. J Respiratory Diseases 21:481-488.

25] Briggs, D.D., Kuritzky L., Boland, C., D.E. Doherty, Hedges, H., Levine, R., Pellegrino, K., Radin, A.M.,

Sahn, S.A. (The National COPD Awareness Panel). 2000. Guidelines for early detection and management of

COPD. J. Respiratory Diseases 21:S5-21.

26] Buch KP, D.E. Doherty. 2001. The significance of office spirometry in assessing lung health. Journal of

COPD Management 2 (2):9-12.

27) Piecoro, L., Potoski, M., Talbert J.C., and D.E. Doherty. 2000. Asthma prevalence: Cost and adherence

with expert guidelines on the utilization od healthcare services and costs in a state Medicaid population. Health

Services Research. June 2001. 36(2):357 - 371.

28] Hirschowitz EA, Hidalgo GE, and D.E. Doherty. Induction of cyclo-oxygenase-2 in non-small cell lung

cancer cells by adenovirus vector infection. 2002. Chest 121:32S.

29] Doherty DE. Early identification and management of chronic obstructive lung disease. What you can do to

reduce the impact of this disabling disease. Postgraduate Medicine 2002;111(6):41-60.

Revised 7/1/16


30] Hirschowitz EA, Hildalgo GE, Doherty DE. Induction of cyclo-oxygenase-2 in non-small cell lung cancer

cells by infection with DeltaE1, DeltaE3 recombinant adenovirus vectors. 2002. Gene Therapy 9:81-84.

31] Doherty, DE, Sahn S.A. Bronchodilation in COPD: Different from asthma. 2002. Journal of Respiratory

Diseases 23:S7-13.

32] Hildalgo GE, Zhong L, Doherty DE, Hirschowitz EA. Plasma PGE-2 levels and altered cytokine profiles in

adherent peripheral blood mononuclear cells in non-small cell lung cancer (NSCLC). Molecular Cancer

2002;1(1):5.

33] Doherty, D.E.. COPD: A case-based approach for primary care: An approach for prevention of COPD.

2002. U.S. Medicine 38 (11):S15-20.

34] Lewis K, D.E. Doherty, Ribes J., Seabolt J.P., and Bensadoun E. Empyema caused by Trichomoniasis.

2003. Chest 123(1):291-92.

35] Doherty D.E. The management of the symptomatic COPD patient. 2003. Clinical Cornerstone 5 (1): 17-27.

36] Zhong L, Peng X, Hidalgo GE, Doherty DE, Stromberg AJ, Hirschowitz EA. Autoantibodies to HSP 70 and

HSP 90 in Sera of Non-Small Cell Lung Cancer Patients. 2003. Cancer Detection and Prevention 27(4):285-290.

37] Doherty, DE. Identification and assessment of chronic obstructive pulmonary disease (COPD) in the

elderly. J Am Med Dir Assoc. 2003. 4(5):S116-120

38] Qureshi MH, Cook-Mills J, Doherty DE, Garvey BA. TNF-alpha-dependent ICAM-1- and VCAM-1-

mediated inflammatory responses are delayed in neonatal mice infected with Pnemocystis carinii. J Immunol.

2003. 171(9):4700-7.

39] Beecham N, D.E. Doherty. Improving COPD Management in the Nursing Home. Part I. The Director

2003. 11(4):182-8.

40] Doherty, DE. Detecting and managing COPD in the younger patient. 2003. Journal of Respiratory Diseases

24 (12):S14-28.

41] Hirschowitz EA, Stromberg A, Doherty DE, Hidalgo GE, Peng X, Zhong L. Identification of circulating

antibodies to tumor-associated proteins for combined use as markers of non-small cell lung cancer. 2004.

Proteomics 4(4):1216-25.

42] Zhong L, Peng X, Hidalgo GE, Doherty DE, Stromberg AJ, Hirschowitz EA. Efficient identification and

use of tumor-associated antibodies as markers of NSCLC. 2004. Chest 125(5):105S-6S.

43] Deaciuc IV, D.E. Doherty, Burikhanov R, Lee EY, Stromberg AJ, DeVilliers WJS. Large-scale gene

profiling of the liver in a mouse model of chronic intragastric ethanol infusion. Accepted for publication in

Journal of Hepatology 40:219-227.

44] Petty TL, D.E. Doherty. The National Lung Health Education Program roots, mission, and future directions.

2004. Respiratory Care 49(6):678-683.

Revised 7/1/16


45] Buch K, Bensadoun E, D.E.Doherty. Anticholinergics for maintenance therapy in patients with COPD.

2004. Journal of COPD Management 5(1):9-14.

46] Doherty DE, Gross NJ, Briggs, DD. Today’s approach to the diagnosis and management of COPD. 2004.

Clinician Reviews 14(1):97-105.

47] Doherty DE, Briggs DD. Chronic obstructive pulmonary disease: Epidemiology, Pathogenesis, disease

course, and prognosis. 2004. Clinical Cornerstone 6 (2): S5-16.

48] Briggs DD, D.E.Doherty. Long-term pharmacologic management of patients with chronic obstructive

pulmonary disease. 2004. Clinical Cornerstone 56(2): S17-28.

49] Doherty DE, Briggs DD. Long-term nonpharmacologic management of patients with chronic obstructive

pulmonary disease. 2004. Clinical Cornerstone 56(2): S29-34.

50] Briggs DD, and panel discussants DE Doherty, et al. Improving diagnosis and management to decrease the

burden of COPD. Postgraduate Medicine Special Report: December 2004

51] Anzueto A., and panel discussants DE Doherty, et al. Preventing the risk of acute exacerbations of COPD.

Postgraduate Medicine Special Report: December 2004

52] Doherty DE, Gross NJ, Briggs DD. Approach to the diagnosis and management of COPD. 2004 Women’s

Health in Primary Care 7(1): 43-51.

53] Doherty DE. The pathophysiology of airways dysfunction. 2004. American Journal of Medicine 117

(12A):11S-23S.

54] Doherty DE. Chronic Obstructive Pulmonary Disease: A Contemporary Overview. 2005. Clinical Advisor

1(1):3-9S.

55] Faiella-Tommasino JF, Doherty DE. Taking on the diagnostic challenges in COPD. 2005. Clinical Advisor

1(1):10-15S.

56] Leonard B., Doherty DE. Multifaceted Management of COPD: Medication and More. 2005. Clinical

Advisor 1(1):16-22S.

57] Doherty DE. Update on the non-pharmacologic therapy of COPD. 2005. J COPD Management 6(3):10-15

58] Mannino DM, Doherty DE, Buist AS. Global Initiative on Obstructive Lung Disease (GOLD) classification

of lung disease and mortality: Findings from the Atherosclerosis Risk in Communities (ARIC) study. 2006.

Respiratory Medicine 100:115-122.

59] Doherty DE – Member of the NHLBI Working Group on Long-Term Oxygen Treatment in COPD. Long-

term Oxygen Treatment in COPD: An NHLBI Workshop Report. 2006. Amer J Resp Crit Care 174:373-378

Revised 7/1/16


60] Doherty DE, TL Petty. Recommendations of the 6th

long-term oxygen therapy consensus conference. 2006.

Respiratory Care 51 (5): 519-525

61] Jarjour NN, Wilson SJ, Koenig SM, Laviolette M, Moore WC, Davis B, Doherty DE, Hamid Q, Israel E,

Kavuru M, Ramsdell JW, Tashkin DP, Reilly DS, Yancey SW, Edwards LD, Stauffer JL, Dorinsky PM,

Djukanovic R. Control of airway inflammation maintained at a lower steroid dose with fluticasone

propionate/salmeterol 100/50mcg. 2006. J. Allergy Clin Immunol 118(1):44-52).

62] Doherty DE, Lawrence G, Nett LM, Petty TL. The National Lung Health Education program (NLHEP).

2006. Proc Am Thorac Soc 3:S45.

63] Sylnkova K, Mannino DM, Martin GS, Morehead RS, Doherty DE. The role of body mass index and

diabetes in the development of organ failure and subsequent mortality in a observational cohort. 2006. Crit Care

10(5):137

64] National Heart Lung Blood Institute Educational Strategy Development Workshop on Chronic Obstructive

Pulmonary Disease (COPD), Sept 22-23,2004. Published as an NIH-NHLBI Periodical in 2006.

65] Doherty DE, Belfer M, Brunton S, Fromer L, Morris C, Snader TC. Consensus Recommendations in

Chronic Obstructive Pulmonary Disease (COPD). 2006. J Family Practice, 55(11):S1-8.

66] Doherty DE. Assessing the prognosis in patients with chronic obstructive lung disease (COPD). 2006.

National Medical Journal of China 86(41):2887-2889

67] Doherty DE, GL Lawrence. The Tenth Anniversary of the National Lung Health Education Program. 2006.

Chest Physician 1(12):19.

68] Doherty DE, Nomura K., Kida K, Ueki J. Long-Term Oxygen Therapy Roundtable: Issue in Japan and the

United States. 2007. Lung Perspectives 15(1):123-132.

69] Doherty DE. Assessing the prognosis of patients with chronic obstructive pulmonary disease. 2007. Journal

of Organ Dysfunction 3(4):250-254

70] D’Souza-El Guindy NB, WJ de Villiers and D.E. Doherty. Acute alcohol intake promotes lung

immunosuppressive environment impairing inflammation. 2007. Alcohol 41(5):335-345

71] Doherty DE, Chapman KR, Martinez FJ, Belfer MH. Issues facing clinicians who manage patients with

COPD. 2007. J. Family Practice, October 2007: S3-4

72] Doherty DE, Chapman KR, Martinez FJ, Belfer MH. Early diagnosis of COPD: Improving outcomes.

2007. J. Family Practice, October 2007: S5-13

73] Chapman KR, Doherty DE, Martinez FJ, Belfer MH. Multifaceted COPD management. 2007. J. Family

Practice, October 2007: S14-24

74] Doherty DE. A Review of the Role of FEV1 in the COPD Paradigm. 2008. Journal of COPD 5:310-318

Revised 7/1/16


75] Djukanovic R, Wilson SJ, Moore WC, Koenig SM, Laviolette M, Bleecker E, Davis WB, Doherty DE,

Olivenstein R, Israel E, Kavuru MS, Floreani A, Kleerup E, Reilly DS, Yancey SW, Edwards LD, Stauffer JL,

Dorinsky PM, Jarjour NN,. Montelukast added to fluticasone propionate does not alter inflammation or

outcomes. 2010. Respiratory Medicine 104:1425-1435

76] Stoller JK, Panos RJ, Krachman S, Doherty DE, Make B and the Long-Term Oxygen Treatment Trial

Group. Oxygen therapy for patients with COPD: Current evidence and the Long-term Oxygen Treatment Trial

(LOTT). 2010. Chest 138:179-187

77] Make B, Krachman S, Panos RJ, Doherty DE, Stoller JK. Oxygen therapy in advanced COPD: In whom

does it work? 2010. Seminars in Respiratory and Critical Care Medicine 31:334-342

78] Blaiss M, Nathan RA, Stoloff SW, Meltzer EO, Murphy KR, Doherty DE. Patient and physician

asthma deterioration terminology: Results from the 2009 Asthma Insight and Management survey. 2012.

Allergy and Asthma Proceedings 33 (1) :47-53. Epublished ahead of print Dec 15, 2011. DOI: http://dx.doi.org/10.2500/aap.2011.32.3520.

79] Murphy KR, Meltzer EO, Blaiss M, Nathan RA, Stoloff SW, Doherty DE. Asthma management and

control in the United States: Results from the 2009 Asthma Insight and Management survey. 2012.

Allergy and Asthma Proceedings 33 (1):54-64. Epublished ahead of print Dec 15, 2011. DOI: http://dx.doi.org/10.2500/aap.2011.32.3518.

80] Meltzer EO, Blaiss M, Nathan RA, Doherty DE, Murphy KR, Stoloff SW. Asthma burden in the

United States: Results from the Asthma Insight and Management survey. 2012. Allergy and Asthma

Proceedings 33 (1): 36-46. Epublished ahead of print Dec 15, 2011. DOI: http://dx.doi.org/10.2500/aap.2011.32.3519.

81] Nathan RA, Meltzer EO, Blaiss M, Murphy KR, Doherty DE, Stoloff SW. Comparison of the Asthma

in America and Asthma Insight and Management surveys: Did asthma burden and care improve in the

United States between 1998 and 2009. 2012. Allergy and Asthma Proceedings 33 (1):65-76. Epublished

ahead of print Dec 15, 2011. DOI: http://dx.doi.org/10.2500/aap.2011.32.3521.

82] Doherty DE. Thomas L. Petty (1932-2009) – Phenomenal clinician, leader, educator, researcher, innovator,

story teller, humanist, friend, and patient advocate who was humble and led by example: Aspen Lung

Conference Tribute. 2011. Proc Am Thorac Soc 8:141

83] Doherty DE, Tashkin DP, Kerwin E, Shekar T, Banerjee S, Knorr B, Staudinger H. Effects of mometasone

furorate/formoterol fumarate fixed-dose combination formulation on chronic obstructive pulmonary disease

(COPD): Results from a 52 week phase three trial in subjects with moderate to very severe COPD. 2012.

International Journal of COPD 7:57-71.

84] Tashkin DP, Doherty DE, Kerwin E, Matiz-Bueno CE, Knorr B, Shekar T, Banerjee S, Staudinger H.

Efficacy and safety of mometasone furorate/formoterol fumarate fixed-dose combination formulation in subjects

with moderate to very severe COPD: Results from a 52 week phase three trial. 2012. International Journal of

COPD 7:43-55.

http://dx.doi.org/10.2500/aap.2011.32.3520




Revised 7/1/16


85] Tashkin DP, Doherty DE, Kerwin E, Matiz-Bueno CE, Knorr B, Shekar T, Banerjee S, Staudinger H.

Efficacy and safety of mometasone furorate/formoterol fumarate fixed-dose combination in subjects with

moderate to very severe Chronic Obstructive Pulmonary Disease: Findings from pooled analysis of two

randomized, placebo-controlled trials. 2012. International Journal of COPD 7:73-86.

86] Maspero J, Cherrez I, Doherty DE, Tashkin DP, Kuna P., Wen-Ling K., Gates D, Nolte H, Chylack LT.

2013. Appraisal of ocular safety with mometasone furoate/formoterol fumarate combination in patients with

COPD or asthma. 2014. Respiratory Medicine 108:1355-1362.

87]

X. MANUSCRIPTS IN PREPARATION

1] Nelsen LM, Norquist JM, Doherty DE, Diette GB, Demuro-Mercon C, Turpin JA, Santanello NC.

Development and validation of the COPD symptom diary (CSD) for patients with chronic obstructive pulmonary

disease. Submitted with revisions for publication to J. of COPD.

2] D’Souza NB and D.E. Doherty. Acute alcohol intoxication sensitizes the lung to bacterial lipopolysaccharide

by affecting expression of multiple early response cytokines and cytokine receptors. Submitted for publication to

Alcoholoism: Clinical and Experimental research.

3] D’Souza NB and D.E. Doherty. Role of ICAM-1 in alcohol-induced immunomodulation of acute lung

inflammation. Re-submitted to Journal of Immunology

4) Khan, T.Z., D.W.H. Riches, and D.E. Doherty. Bleomycin-induced pulmonary fibrosis in C3H/HeJ mice:

Absence of local TNF alpha expression in the lungs. In process of resubmission to Amer. J. Respiratory Cell and

Molecular Biology, revisions requested.

5) Desaki, M., D.W.H. Riches, and D.E. Doherty. Macrophage plasticity during pulmonary fibrosis in mice.

Submitted to AJP Lung, revisions requested.

6) Doherty, D.E., P.S. Tobias, R.J. Ulevitch, and G.S. Worthen. Lipopolysaccharide Binding Protein (LBP)

enhances LPS-induced monocyte adherence to endothelial cells: The role of CD14. Submitted to Amer. J.

Respiratory Cell and Molecular Biology.

7) Desaki, M., and D.E. Doherty. Poly [I:C] plus aminoguanidine ameliorates bleomycin-induced pulmonary

fibrosis. Manuscript in preparation.

8) Nakano, J., K. Nakano, and D.E. Doherty. Mononuclear phagocyte accumulation in the lungs during

bleomycin-induced pulmonary fibrosis: Kinetics of macrophage retention and clearance. Manuscript in

preparation.

9) Nakano, K., J. Nakano, H. Flodgaard, and D.E. Doherty. A neutrophil-derived protein induces monocyte-

specific migration into the lungs of rabbits. Manuscript in preparation.

Revised 7/1/16


10) Doherty, D.E., and L. Zagarella. Tumor necrosis factor prolongs LPS-induced monocyte retention in the

lung. Manuscript in preparation.

11) D’Souza, N.B., and D.E. Doherty. Modulation of rat lung apoptotic rate by gram negative bacterial

lipopolysaccharide. Manuscript in preparation.

INVITED NON-PEER REVIEWED MANUSCRIPTS:

Doherty, D.E., and G. Lawrence. National Lung Health Education Program helps to increase COPD awareness.

2006. AARC Times (11): 105

Doherty, D.E. and Hansen-Flaschen J. Ways to breathe easier: How to recognize and treat ailments that can

affect your lungs. 2011. Consumer Reports on Health 23(11):1-3

Doherty, DE., by Larry Armour- getting the facts: Understanding COPD. 2012. Sports Illustrated 117:(20) 34.

November 19, 2012.

BOOKS, BOOK CHAPTERS, MONOGRAPHS:

1) Doherty, D.E., G.S. Worthen, and P.M. Henson. 1993. Inflammation in the interstitial lung diseases. Chapter

2 in Interstitial Lung Disease, second edition, ed. Schwarz MI and King TE, BC Decker Inc, Philadelphia.

2) Henson, P.M., D.E. Doherty, D.W.H. Riches, P. Parsons, and G.S.W. Worthen. 1994. LPS and cytokines in

lung injury. Chapter 13 in Endotoxin and the Lungs, Lung Biology in Health and Disease series, ed. Brigham K

Marcel Decker Inc.

3) D.E. Doherty. 2001. Procedures in Sleep Medicine. Frontline Pulmonary Procedures and Interventions.

Snowdrift Publications, Inc.

4) Petty TL, D.E. Doherty. 2001. Save Your Breath, America: Prevent Emphysema. Monograph for patients.

5) Petty TL, D.E. Doherty. 2001. Prevent Emphysema Now. Monograph for physicians.

6) D.E. Doherty. 2002. Frontline Advice for COPD Patients. Snowdrift Publications, Inc.

7) Doherty, D.E. and Make B. (Eds.) Editor- Educational Review Manual in Pulmonary Disease. New York:

Castle Connolly Graduate Medical Publishing, 2003.

8) Buch K.P. and DE Doherty. 2003. Chronic Obstructive Lung Disease. Chapter in Educational Review

Manual in Pulmonary Disease. Eds. Doherty D.E. and Make B., New York: Castle Connolly Graduate Medical

Publishing.

Revised 7/1/16


9) Petty TL, D.E. Doherty. 2003. Save Your Breath, America: Prevent Emphysema. Monograph for patients.

2nd edition

10) Petty TL, D.E. Doherty. 2003. Prevent Emphysema Now. Monograph for physicians. 2nd

edition

11) Doherty, D.E., Petty TL, Seebass JS. 2003. The Early Recognition and Management of Chronic

Obstructive Pulmonary Disease. Monograph.

12) Doherty.D.E. 2004. Frontline Update: COPD New Concepts, New Therapies. Snowdrift Publications, Inc.

13) Doherty, D.E. and Make B. (Eds.) Editor- 2nd

Edition Educational Review Manual in Pulmonary Disease.

New York: Castle Connolly Graduate Medical Publishing, 2006.

14) Buch K.P. and D.E. Doherty. 2006. Chronic Obstructive Lung Disease. Chapter in 2nd

Edition

Educational Review Manual in Pulmonary Disease. Eds. Doherty D.E. and Make B., New York: Castle

Connolly Graduate Medical Publishing.

15) D.E. Doherty, Petty TL. 2006. Save Your Breath, America: Prevent Emphysema. Monograph for patients.

3rd

edition

16) TL Petty, RW McCoy, DE Doherty. 2006. Long-term oxygen therapy (LTOT): History, Scientific

Foundations, and Emerging technologies.

17) Doherty, DE, Ayers J. 2006 Understanding Asthma. Family Doctors Publications, Poole, Dorset, UK.

18) D.E. Doherty Common Medications in COPD. 2006 Monograph for the National Lung Health Education

Program.

19) D.E.Doherty, Buch K.P. 2007. Early Diagnosis of COPD: Usefulness, tools and actors. Chapter in Clinical

Management of COPD, 2nd

Edition. Editors : S Rennard, R Rodriguez Roisin, G Huchon, N Roche. Taylor and

Francis Group, LLC, New York, NY.

20) Britt EJ, Cote CC, Criner G, Doherty DE, Hedges HH, Littner M, Niewoehner D. 2007. Monograph: A

case-based approach to proper diagnosis and management of the COPD patient.

21) Doherty, D.E. and Make B. (Eds.) Editor- 3rd

Edition Educational Review Manual in Pulmonary Disease.

New York: Castle Connolly Graduate Medical Publishing, 2008.

22) D.E. Doherty. 2008. Chronic Obstructive Lung Disease. Chapter in 3rd

Edition Educational Review

Manual in Pulmonary Disease. Eds. Doherty D.E. and Make B., New York: Castle Connolly Graduate Medical

Publishing.

23) K. Saito editor, D.E. Doherty Section editor. 2008. Progress in Scale Modeling: Selected Papers from

Meetings of the International Society for Scale Modeling (ISSM), 2000-2007. Springer-Verlag Publishers, New

York, NY.

D.E. Doherty, Konishi T., Ida T. Introduction to Part IV –Medical – Conceptual, Practical, Translational

into Practice. pp 429-431.

Revised 7/1/16


D.E. Doherty. Monocyte lung retention during normal conditions (Health) and during disease states

(Endotoxemia): A medical application of scale modeling. pp 455-456

D.E. Doherty, Downey GP, Schwab B, Elson E, Worthen GS. Lipopolysaccharide-induced monocyte

retention in the lung: Role of monocyte stiffness, actin assembly, and CD18-dependent adherence. pp 457-

485.

24) D.E. Doherty, Christopher K., O’Donohue W.J. 2013. Second edition. Understanding Oxygen Therapy: A

patient guide to Long-Term Supplemental Oxygen. Published by the National Home Oxygen Patients

Association (NHOPA).

COMMENTARIES AND EDITORIALS:

1) Doherty, D.E. Commentary in Drug Selection Update, Analysis of Clinical Data April 1999 section of

Pulmonary Reviews with regard to article by Friedman et. al. Pharmacoeconomic evaluation of a

combination of ipratropium plus albuterol compared with ipratropium alone and albuterol alone. Chest

115:635-641, 1999.

2) Doherty DE. Chronic Obstructive Pulmonary Disease (COPD). 2004 Physicians Weekly 21(34):1

3) Doherty, DE. Documentation of Airflow Obstruction Is Essential to Confirm the Diagnosis of COPD:

Are Handheld Spirometers in an Office Setting Valid? Invited Editorial. Respiratory Care accepted for

publication in April 2008

4) Consumer Reports health edition- Interviewed and quoted on article covering Dyspnea in Adults,

published September-October 2011.

5) Women and COPD featured in article November 2013 in Kentucky Doctor Magazine, interviewed and

quoted

6) COPD and the Role of Caregivers- interviewed, quoted, and authored a side bar of the main article which

reviewed COPD. December 2013 issue of Ability magazine.

7) Doherty, DE. COPD troubling, but treatable: Respiratory disease now the 3rd

leading cause of death.

Letters to the Editor-Opinion Section, The State Journal, page D3, Frankfort, KY. December 8, 2013

state-journal.com

LETTERS TO THE EDITOR:

1) Doherty, D.E. COPD Awareness Month. Medscape Pulmonary Medicine eJournal 5(6), 2001.

ABSTRACTS AND PAPERS PRESENTED AT MEETINGS:

1) Doherty, D.E., and E. Neuwelt. 1977. Infusion of xenogenic lymphocytes into the subarachnoid space of

rabbits. Federation Proceedings 1977, Amer. Assoc. of Cancer Res.:p10.

2) Karpetsky, T.P., R.D. Wortzel, J. Poole, B. Okita, K. Shriver, and D.E. Doherty, A. Rahman, and C.C. Levy.

1979. Detection of ribonuclease activity using polynucleotide-polyacrylamide gel electrophoresis. Federation

Proceedings 38(3):322.

3) Doherty, D.E., C. Haslett, M.G. Tonneson, and P.M. Henson. 1985. Adhesion of human monocytes induced

by chemotactic peptides. Federation Proceedings 1985, Anaheim, California.

Revised 7/1/16


4) Doherty, D.E., G.S. Worthen, C. Haslett, and P.M. Henson. 1986. Pulmonary accumulation of monocytes in

chemotactic peptide induced lung inflammation. Amer. Rev. Resp. Dis. 133(4):A171, Kansas City, Kansas.

5) Doherty, D.E., R.A.F. Clarke, and P.M. Henson. 1987. The Induction Of Monocyte Accumulation

Independent Of Neutrophils By Fibronectin Fragments In The Lung. Federation Proceedings 46(3):1040.,

Washington,D.C.

6) Martin, B.A., D.E. Doherty, G. Downey, G.S. Worthen, P.M. Henson, and J.C. Hogg. 1987. Comparison of

Polymorphonuclear (PMN) and Mononuclear Leukocyte Transit Through the Rabbit Lung. Federation

Proceedings 46(3):662., Washington, DC.

7) Doherty, D.E., R.A.F. Clark, and P.M. Henson. 1987. Neutrophil Dependence of Monocyte Accumulation In

The Rabbit Lung. Amer. Rev. Resp. Dis. 135(4):A335, New Orleans, Louisiana.

8) Doherty, D.E., R.A.F. Clark, J.A. McDonald, and P.M. Henson. 1988. Fibronectin Fragment- Induced

Monocyte Migration In The Rabbit Lung. FASEB J. 2(5):A1178, Las Vegas, Nevada.

9) Downey, G.P., D.E. Doherty, P.M. Henson, and G.S. Worthen. 1988. Size and Deformability Determine

Retention of Leukocytes in Model Capillaries. FASEB J. 2(6):A1603, Las Vegas, Nevada.

10) Doherty, D.E., G.S. Worthen, and P.M. Henson. 1988. LPS-Induced Monocyte Adherence (In Vitro) During

Endotoxemia in the Rabbit. Amer. Rev. Resp. Dis. 137(4):A44, Las Vegas, Nevada.

11) Haslett, C., G.P. Downey, D.E. Doherty, and P.M. Henson. 1988. Early Cessation of Neutrophil Migration

After Intrapulmonary Instillation of C5f des arg (C5f) in Rabbits. Amer. Rev. Resp. Dis. 137(4):A44, Las Vegas,

Nevada.

12) Doherty, D.E., P.M. Henson, and G.S. Worthen. 1989. LPS-Stimulated Monocyte Adherence: Effects on

the Monocyte and Endothelial Cell. FASEB J. 3(3):A319, New Orleans, Louisiana.

13) Doherty, D.E., P.M. Henson, and G.S. Worthen. 1989. Direct Induction of Monocyte Retention in the

Rabbit Lung by Bacterial Lipopolysaccharide (LPS). Amer. Rev. Resp. Dis. 139(4):A304, Cincinnati, Ohio.

14) Doherty, D.E., B. Schawb, E. Elson, and G. S. Worthen. 1990. LPS-Induced Monocyte Capillary Retention:

Role of Cell Stiffness. Presented at the International Endotoxin Society Meeting in San Diego, Calf. 5/90.

15) Doherty, D.E., B. Schawb, E. Elson, and G.S. Worthen. 1990. Lipopolysaccharide (LPS)-Induced

Monocyte Lung Retention: The Role of Cell Stiffness. Amer. Rev. Resp. Dis. 141(4):A642, Boston, MA.

16) Shaw, R.J., H. Benedict, D.E. Doherty, A. Ritter, T.E. King Jr., and R.A.F. Clark. 1990. Cascades of gene

activation during monocyte to macrophage differentiation: Adherence-dependent increase in PDGF(B) mRNA

and the regulatory genes c-fos, c-jun, EGR2. Amer. Rev. Resp. Dis. 141:A352, Boston, MA.

17) D.E. Doherty, N. Hirose, and R.M. Cherniack. 1990. Noninvasive assessment of monocyte lung retention

and migration during bleomycin-induced lung injury in the rabbit. Amer. Rev. Resp. Dis. 141:A642, Boston,

MA.

Revised 7/1/16


18) Shaw, R.J., D.E. Doherty, A. Ritter, S.H. Benedict, and R.A.F. Clark. Differentiation of monocytes to "pro-

fibrotic" cells encoding PDGF(B) mRNA. Presented at Joint Meeting of SEP-SEPCR, Sept. 9-14, 1990, London,

England.

19) Hirose, N., D.A. Lynch, R.M. Cherniack, and D.E. Doherty. 1991. Correlation between high resolution lung

CT and tissue morphometry in bleomycin-induced lung injury in the rabbit. Amer. Rev. Resp. Dis. 143:A56,

Anaheim, CA.

20) Doherty, D.E. and G.S. Worthen. 1991. Lipopolysaccharide-induced monocyte lung retention in the rabbit:

The role of the CD11/CD18 leukocyte adhesion complex and cell stiffness. Amer. Rev. Resp. Dis. 143:A583,

Anaheim, CA.

21) Lynch, D.A., N. Hirose, R.M. Cherniack, and D.E. Doherty. 1991. Bleomycin-induced lung injury in the

rabbit: HRCT features, quantitation and correlation with tissue morphometry. Presented at The Society of

Thoracic Radiology Annual Meeting, Toronto, Ontario, May 1991.

22) Doherty, D.E., P.S. Tobias, R.J. Ulevitch, and G.S. Worthen. 1992. The role of LPS-binding protein and

CD14 in LPS-induced monocyte adherence. Amer. Rev. Resp. Dis. 145:A666, Miami, FL.

23) Khan, T.Z., D.W.H. Riches, and D.E. Doherty. 1993. Induction of pulmonary fibrosis by bleomycin in the

absence of TNF-alpha expression in C3H/HeJ mice. Amer. Rev. Resp. Dis. 147:A755, San Francisco, CA.

24) Nakano, J., K. Nakano, and D.E. Doherty. 1993. Prolonged macrophage retention in the lung during

bleomycin-induced pulmonary fibrosis. Amer. Rev. Resp. Dis. 147:A73, San Francisco, CA.

25) Doherty D.E., J. Leadbeater, and L. Zagarella. 1993. LPS-induced monocyte retention in model capillaries:

Role of plasma and the LPS receptor CD14. Amer. Rev. Resp. Dis. 147:A245, San Francisco, CA.

26) Doherty, D.E., and G.S. Worthen. 1994. Lipopolysaccharide-induced monocyte retention in the lungs of

rabbits: The role of cell stiffness and the CD11/CD18 leukocyte adhesion complex. Presented at the 36th annual

Thomas L. Petty Aspen Lung Conference, Aspen, CO., June, 1993, Chest 105:108S.

27) Bratton, D.L., Q. Hamid, J.M. Kailey, D.E. Doherty, and D.Y.M. Leung. 1994. GM-CSF inhibition of

monocyte (MØ) apoptosis contributes to the chronic MØ activation of atopic dermatitis (AD). Submitted to the

American Academy of Allergy and Immunology for presentation at the annual meeting 1994, Anaheim, CA.

28) Nakano, K., J. Nakano, and D.E. Doherty. 1994. A neutrophil-derived heparin-binding protein induces

monocyte migration into rabbit lungs. Amer. Rev. Resp. Dis. 149:A1098, Boston, MA.

29) Doherty, D.E., J. Leadbeater, and L Zagarella. 1994. Soluble human TNF receptor (p80) prevents TNF-

induced human monocyte adhesion and retention in model pulmonary capillaries in vitro, and attenuates

prolonged monocyte retention in the lungs of endotoxemic rabbits. Amer. J. Respir. Crit. Care Med.

149:A1100, Boston, MA.

30) Doherty, D.E., J. Leadbeater, L. Zagarella, and E.J. Sullivan. 1994. Bactericidal/Permeability Increasing

Protein (rBPI21) attenuates LPS-induced human monocyte adhesion and retention in model pulmonary

Revised 7/1/16


capillaries in vitro, and rabbit monocyte retention in the lungs of endotoxemic rabbits in vivo. Amer. J. Respir.

Crit. Care Med. 149:A863, Boston, MA.

31) Lynch, D.A., N. Hirose, R.M. Cherniack, and D.E. Doherty. 1994. Bleomycin-induced lung fibrosis:

Correlation between HRCT-determined abnormalities and lung function in an animal model. Amer. J. Respir.

Crit. Care Med. 149:A383, Boston, MA.

32) Doherty, D.E., J. Leadbeater, and L. Zagarella. LPS-induced monocyte deformability and adhesion: The

role of LBP-CD14. FASEB J 8:A316, Anaheim, CA.

33) May, K.R., D.Y.M. Leung, D.E. Doherty, and D.L. Bratton. 1995. Staphylococcal toxic shock syndrome

toxin (TSST-1) reduces apoptosis of monocytes in atopic dermatitis. Presented at the American Academy of

Allergy and Immunology Meetings, February 1995, New York, New York.

34) Doherty, D.E., and E.J. Sullivan. 1995. Bactericidal/Permeability Increasing Protein (BPI21) attenuates

LPS-induced human neutrophil adhesion in vitro, and rabbit neutrophil retention in the lungs of endotoxemic

rabbits in vivo. Amer. J. Respir. Crit. Care Med. 151:A343, Seattle, WA.

35) Doherty, D.E., M. Desaki, and C. Majewski. 1996. ICAM-1 deficiency delays macrophage clearance from

the lungs and enhances pulmonary fibrosis. Amer. J. Respir. Crit. Care Med. 153:A13, New Orleans, Louisiana.

36) Desaki, M., D.W.H. Riches, and D.E. Doherty. Macrophage plasticity during pulmonary fibrosis. 1996.

Amer. J. Respir. Crit. Care Med. 153:A767, New Orleans, Louisiana.

37) Desaki, M., and D.E. Doherty. Poly [I:C] plus an inducible nitric oxide synthase inhibitor ameliorates

bleomycin-induced pulmonary fibrosis in mice. 1997. Amer. J. Respir. Crit. Care Med. 155:A317, San

Francisco, California.

38) Morris, P.E., L.E. Olmstaed, D.A. Cohen, P. Sullivan, S.W. Scheff, and D.E. Doherty. Lung inflammation

in a murine system of head injury. Presented at the National Neurotrauma Society Meetings, Oct 24-15, 1997,

New Orleans, Louisiana. 1997. J. of Neurotrauma 14:795 Awarded as one of the 12 best abstracts submitted

(n=192) and selected for oral presentation at this national meeting.

39) Doherty, D.E., B.A. Hilty, and C. Majewski. ICAM-1 deficiency enhances the development of pulmonary

fibrosis in bleomycin-treated mice. 1998. Amer. J. Respir. Crit. Care Med. 157:A715, Chicago, Illinois.

40) Doherty, D.E., J. Nakano, and K. Nakano. Neutrophil-derived heparin-binding protein (HBP): A monocyte-

specific chemoattractant which induces monocyte migration into rabbit lungs in vivo. 1998. Presented at the

41st Annual Thomas L. Petty Aspen Lung Conference on Acute Lung Injury, Aspen, Colorado. Will be

published in Chest, 1999.

41) D'Souza, N.B., and D.E. Doherty. Chronic alcohol treatment of rats sensitizes the lung to LPS-

induced apoptosis. Presented at the 22nd annual Research Society on Alcoholism Scientific Meeting,

1999, Santa Barbara, CA. Alcoholism Clinical and Experimental Research 23(5) 26A abstract 122.

42) Dagastani, A., D.E. Doherty, and E. Bensadoun. Hydrochlorthiazide-induced pulmonary edema. Accepted

for presentation at the American Lung Association of Kentucky Annual Meeting 3/00, Lexington, KY.

Revised 7/1/16


43) Masood, A., D.E. Doherty, and J.R. McCormick. Broncholithiasis mimicking pulmonary malignancy.

Accepted for presentation at the American Lung Association of Kentucky Annual Meeting 3/00, Lexington, KY.

44) D’Souza, N.B., B.A. Garvey, and D.E. Doherty. Effect of chronic alcohol (EtOH) ingestion on lung

apoptosis in response to opportunistic infection. Presented at the 23rd annual Research Society on Alcoholism

(RSA) Scientific Meeting, June 24, 2001, Denver, CO. 2000. Alcoholism Clinical and Experimental Research

24(5):19A abstract 78

45) Hirschowitz E, Hildalgo G, D.E. Doherty. 2001. Induction of cyclo-oxygenase-2 in small cell lung cancer

cells by adenovirus vector infection. 44th Annual Thomas L. Petty Aspen Lung Conference on Pulmonary

Genetics, Genomics, and Gene Therapy, June 6-9, 2001, Aspen, CO., Chest 121:32S

46) D’Souza NB, Kainath D, Westberry KF, D.E. Doherty. Alcohol (EtOH) intoxication alters the basal rate of

mouse lung apoptosis sensitizing it to bacterial endotoxin (LPS). 24th Annual RSA Scientific Meeting, June 22,

2001, Montreal, Canada. 2001. Alcoholism Clinical and Experimental Research 25(5):26A abstract 117

47) D’Souza NB, Woosley CE, Dunn RD, D.E. Doherty. Alcohol (EtOH) intoxication alters mRNA expression

of lung inflammatory cytokines and their receptors sensitizing it to bacterial endotoxin (LPS). 24th Annual RSA

Scientific Meeting, June 22, 2001, Montreal, Canada. 2001. Alcoholism Clinical and Experimental Research

25(5):26A abstract 118

48) Lewis K, Bensadoun E, Ribes, and D.E. Doherty. Empyema caused by Trichomoniasis. Presented at the

American Lung Association of Kentucky and the Kentucky Thoracic Society Annual meetings, Lexington, KY

March, 2001.

49) Lewis K, Bensadoun E, Ribes, and D.E. Doherty. Empyema caused by Trichomoniasis. Presented at the

American College of Chest Physicians National Convention, Atlanta, GA and was awarded “Best Abstract’ of

the session, based on content and presentation (by Dr. K. Lewis). Chest 2001.

50) Qureshi MH, Schuer K, Young W, Hollifield M, Doherty DE, D’Souza N, et. Al. Inefficient host-response

of neonates to P. carinii infection is associated with inadequate adhesion molecule upregulation. Presented at the

ASM Conferewnce on Immunity to Bacterial, Viral, and Protozoal Pathogens, March 20-24, 2002, Savannah,

GA.

51) Zhong L, GE Hidalgo, DE Doherty, E.A. Hirschowitz. Identification of tumor antigens from phage-

displayed cDNA lung tumor library recognized by autoantibodies in non-small cell lung cancer (NSCLC) patient

serum. Presented at the American Thoracic Society annual meeting May, 2001, Atlanta, GA.

52) D’Souza N, Burikhanov R, Woosley C, Kainath D, Doherty DE. Lung inflammatory response to bacterial

lipopolysaccharide (LPS) in alcohol (EtOH)-fed interleukin-10 (IL-10) knockout mice. Presented at 2002 25th

Annual RSA/ISBRA Scientific Meeting, New Orleans, LA.

53) D’Souza NB, Kainath D, Doherty DE. Role of ICAM-1 in alcohol-induced immnunomodulation of acute

lung inflammation. Presented at the 2003 26th Annual RSA/ISBRA Scientific Meeting, Orlando, FL.

Revised 7/1/16


54) Zhong L, Peng X, Hildalgo GE, Doherty DE, Stromberg AS, Hirschowitz EA. Efficient identification and

use of tumor-associated antibodies as markers of non-small cell lung carcinoma. Presented at the 46th

Annual

Thomas L. Petty Aspen Lung Conference, Aspen, CO, 2003.

55) D’Souza N, Deaciuc I, Peng X, Doherty DE. Gene micrarray analysis of the lungs from mice fed alcohol

(EtOH) long-term. Presented at the 27th

Annual Meeting of the Research Society on Alcoholism, June 26-30,

2004, Vancouver, Canada.

56) Mannino DM, Holguin F, Baron A. Doherty DE, Buist AS. GOLD classification of COPD and incident

lung cancer: findings from a cohort study. Presented at the European respiratory Society 2004 annual meeting.

57) Mannino DM, Savage-Brown A, Doherty DE, Buist AS. GOLD classification of COPD and subsequent

mortality: findings from a cohort study. Presented at the European respiratory Society 2004 annual meeting.

58) Darwanto, Doherty DE, Klein C, baker TN, D’Souza NB. Chronic alcohol intake modulates Streptococcus

pneumonia-induced murine lung apoptosis through a caspases-dependent pathaway. Presented at the 28th

Annual

Scientific Meeting of the Research Society on Alcoholism, June 25-28, 2005, Santa Barbara, CA.

59) Doherty DE, Lawrence G, Calvillo M, Nelson A, Hallmon D, Valdez C. National Lung Health Education

Program (NLHEP) COPD awareness poster survey. Presented at the 52nd

International respiratory Congress De

11, 2006, Las Vegas. 2006. Respiratory Care 51(11);1279.

60) Doherty DE, Meltzer EO, Stoloff SW, Murphy KR, Nathan RA, Blaiss M. Patient and physician differences

in understanding asthma symptom deterioration terminal;ogy from the Asthma Insight and Management (AIM)

Survey. Presented at the American Academy of Allergy, Asthma and Immunology Annual Meeting, March

2011, San Francisco, CA

61) Stoloff SW, Nathan RA, Blaiss M, Meltzer EO, Doherty DE, Murphy KR. Physician-reported asthma

control and management from the Asthma Insight and Management (AIM) survey. Presented at the American

Academy of Allergy, Asthma and Immunology Annual Meeting, March 2011, San Francisco, CA

62) Meltzer EO, Doherty DE, Nathan RA, Murphy KR, Stoloff SW, Blaiss M. The overall burden experienced

by asthma patients interviewed in the Asthma Insight and Management (AIM) survey. Presented at the

American Academy of Allergy, Asthma and Immunology Annual Meeting, March 2011, San Francisco, CA

63) Nathan RA, Stoloff SW, Blaiss M, Meltzer EO, Doherty DE, Murphy KR. Comparing Astham in America

(AIA) and Asthma Insight and Management (AIM) surveys- Did asthma burden and management improve in the

United States between 1998 and 2009? Presented at the American Academy of Allergy, Asthma and

Immunology Annual Meeting, March 2011, San Francisco, CA

64) Stoloff SW, Blaiss M, Nathan RA, Doherty DE, Meltzer EO, Murphy KR. Patient-Physician

communication in the United States: Results from the Asthma Insight and Management Survey. Presented at the

America Thoracic Society International Conference, May 2011, Denver, Colorado.

65) Nathan RA, Meltzer EO, Blaiss M, Murphy KR, Doherty DE, Stoloff SW. Awareness of and adherence to

National Asthma Education and Prevention Program (NAEPP) Guidelines by asthma specialists and primary

care physicians: Comparison of results from the 2009 Asthma Insight and Management (AIM) and 1998 Asthma

Revised 7/1/16


in America surveys. Presented at the American College of Chest Physicians annual meeting, October 2011,

Honolulu, Hawaii.

66) Murphy KR, Meltzer EO, Blaiss M, Nathan RA, Stoloff SW, Doherty DE. Uncontrolled asthma is a

predictor of severe asthma episodes: Results from the Asthma Insight and Management (AIM) survey. Presented

at the American College of Chest Physicians annual meeting, October 2011, Honolulu, Hawaii.

67) Matiz-Bueno CE, Doherty DE, Kerwin E, Tashkin DP, Shekar T, Banerjee S, Sadeh J. The long-term safety

characteristics of mometasone furoate/formoterol for the treatment of moderate to very severe chronic

obstructive pulmonary disease: Pooled findings from two 1-year multicenter clinical trials. Presented at the

American College of Chest Physicians annual meeting, October 2011, Honolulu, Hawaii.

68) Tashkin DP, Doherty DE, Kerwin E, Matiz-Bueno CE, Shekar T, Banerjee S, Sadeh J. The effect of

mometasone furoate/formoterol combination therapy on chronic obstructive pulmonary disease (COPD)

exacerbations: Results from two phase three trails in subjects with moderate to very severe COPD. Presented at

the American College of Chest Physicians annual meeting, October 2011, Honolulu, Hawaii.

69) Kerwin E, Tashkin DP, Matiz-Bueno CE, Doherty DE, Shekar T, Banerjee S, Sadeh J. Quality of life

following 26 weeks of mometasone furoate/formoterol therapy: Results from two phase three trials in subjects

with moderate to very severe chronic obstructive pulmonary disease. Presented at the American College of

Chest Physicians annual meeting, October 2011, Honolulu, Hawaii.

70) Doherty DE, Tashkin DP, Kerwin E, Matiz-Bueno CE, Shekar T, Banerjee S, Sadeh J. Efficacy and safety

of mometasone furoate/formoterol in subjects with moderate to very severe chronic obstructive pulmonary

disease: Results from two phase three 26-week trials. Presented at the American College of Chest Physicians

annual meeting, October 2011, Honolulu, Hawaii.

71) Tashkin DP, Matiz-Bueno CE, Kerwin E, Doherty DE, Shekar T, Banerjee S, Knorr B, Staudinger H.

Clinical efficacy and safety of combined mometasone furoate and formoterol in patients with moderate to very

severe chronic obstructive pulmonary disease (COPD). Accepted for presentation at the 2012 annual meeting of

the American Academy of Allergy Asthma and Immunology, Orlando, Florida.

72) Doherty DE, Kerwin E, Tashkin DP, Shekar T, Banerjee S, Knorr B, Staudinger H. Combined mometasone

furoate and formoterol in patients with moderate to very severe chronic obstructive pulmonary disease (COPD):

Phase 3 efficacy and safety study. Accepted for presentation at the 2012 annual meeting of the American

Academy of Allergy Asthma and Immunology, Orlando, Florida.

73) Doherty DE, Tashkin D, Harrison T, Engel M, Schmidt H, Moroni-Zentgraf P, Kerstjens HAM.

Improvements in lung function with tiotropium as add-on controller therapy to ICS+LABA for patients with

symptomatic severe asthma. Accepted for slide/oral presentation at the 2013 annual meeting of the American

College of Chest Physicians, October 28, 2013 in Chicago, IL.

74) Dahl R, Doherty DE, Corren J, Karpel J, Kerstjens HAM, Engel M, Moroni-Zentgraf P, Schmidt H,

Hashimoto S. Once-daily tiotropium Respimat improves lung function in patients with severe symptomatic

asthma independent of leukotriene modifier use. Presented as a poster at the American Academy of Allergy,

Asthma & Immunology Annual Meeting February 28 – March 4, 2014, San Diego, CA.

Revised 7/1/16


75) Doherty DE, Tashkin DP, Harrison TW, Engel M, Schmidt H, Moroni-Zentgraf P, Kerstjens HAM.

Improvements in lung function with tiotropium as add-on therapy to ICS+LABA for patients with symptomatic

severe asthma. Presented as a poster at the Canadian Respiratory Conference, April 24-26, 2014, in Calgary,

Alberta.

76) Doherty DE, Tashkin DP, Harrison TW, Engel M, Schmidt H, Moroni-Zentgraf P, Kerstjens HAM.

Improvements in lung function with tiotropium as add-on therapy to ICS+LABA for patients with symptomatic

severe asthma. Presented as a poster at the Canadian Pharmacists Conference, May 31-June 3 in Saskatoon, SK.

77) Doherty DE, Castro M., Morini-Zentgraf P., Engel M,. Luhmann R., and Buhl R. Tiotropium Respimat

add-on therapy improves lung function, as measured by peak expiratory flow, in adults across severities of

symptomatic asthma. Presented at the American Thoracic Society International Conference in Denver,

Colorado May 2015.

78) Ortiz GR, Moroni-Zentgraf P, Engel M, Muller A, Doherty DE, Bleecker ER, Kerstjens HAM. Once daily

Tiotropium Respimat add-on to ICS +/- LABA improves lung function and is well tolerated in patients aged > 65

years with asthma. Presented at the 2015 annual meeting of the American Association Physician Assistants, May

23-17, 2015, San Francisco, CA.

79) Hayden ML, Moroni-Zentgraf P, Engel M, Muller A, Doherty DE, Bleeker ER, Kerstjens HAM. Once daily

tiotropium Respimat add-on to ICS+ LABA improves lung function and is well tolerated in patients aged > 65

years with asthma. Presented at the American Association of Nurse Practitioners annual conference June 9-14,

2015, New Orleans, Louisiana.

80) Doherty DE, Castro M., Morini-Zentgraf P., Engel M,. Luhmann R., and Buhl R. Tiotropium Respimat

add-on therapy improves lung function, as measured by peak expiratory flow, in adults across severities of

symptomatic asthma. Presented at the Asian Pacific Respiratory Society meetings December 3rd

- 6th

, 2016,

Kuala Lumpur, Malaysia. Abstract previously presented at the ATS 2015 international meetings.

81) Doherty DE, Halpin D, Bateman E, Paggiaro P, Bleecker E, Engel M, Moroni-Zentgraf P, Schmidt H, and

Kerstjens HAM. Once-daily tiotropium respimat add-on to at least ICS maintenance therapy reduces

exacerbation risk in patients with uncontrolled symptomatic asthma. Presented at the Asian Pacific Respiratory

Society meetings December 3rd

- 6th

,2016, Kuala Lumpur, Malaysia.

82) Kato M,. Doherty DE, Castro M, Moroni-Zentgraf P, Engel M, Luhmann R, Buhl R. Tiotropium Respimat

add-on therapy improves lung function, as measured by peak expiratory flow, in adult patients across severities

of symptomatic asthma. Oral presentation at the 65th

Annual Japanese Society of Allergogology (JSA), June 17,

2016, Tokyo, Japan.

XI. RESEARCH GRANTS, CONTRACTS AND SPECIAL GRANTS

A. Current Research Grant Support (direct costs):

1] Grant Number: NIH:NHLBI-HR-06-07

Title: Long-term Oxygen Treatment Trial (LOTT) – Regional Clinical Centers (RCCs)

Principal Investigator: Dennis E. Doherty, M.D. for University of Kentucky Center

Revised 7/1/16


Award Period: 10/30/06 – 9/30/15 Total Award Budget: $1,356,056 + capitation

B. Previous Grant Support:

55] Grant Number: Protocol 205.416

Title: A Phase III randomized, double-blind, placebo-controlled, parallel-group trial to evaluate efficacy and

safety of tiotropium inhalation solution delivered via Respimat inhaler (5ug/day) over 48 weeks as add-on

controller therapy on top of usual care in patients with severe persistent asthma

Principal Investigator: Dennis E. Doherty, M.D.

Award Period: 5-1-09 – 4-30-11 Total Award budget: $54,000

54] Grant Number: Protocol P04230

Title: A Randomized Placebo-controlled Efficacy and Safety Study of One Year Treatment Duration With

High- and Medium-Dose Inhaled Mometasone Furoate/Formoterol Combination Formulation Compared

With Formoterol and High-Dose Inhaled Mometasone Furoate Monotherapy In Subjects With Moderate to

Severe COPD



53] Grant Number: Protocol A4471008/205.365

Title: A 24 Week, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the

Efficacy and Safety of 18 mcg of Tiotropium Inhalation capsules Administered by HandiHaler Once-Daily

Plus prn Albuterol (Salbutamol) in Chronic Obstructive Pulmonary Disease Subjects Naïve to Maintenance

Therapy



52] Grant Number: NIH: RO1

Title: Alcohol, Apoptosis and Lung Opportunistic Infections

Co-Principal Investigator: Dennis E. Doherty, M.D. Principal Investigator: Nympha D’Souza, Ph.D.

Award Period: 4/01/03 - 3/31/10 Total Award Budget: $1,000,000

Reviewed and Scored: 8.1 percentile

51] Grant Number: CSP560 - Veterans Administration Cooperative Study

Title: Bronchitis and Emphysema Advice and Training to Reduce Hospitalization (BREATH)

Principal Investigator: Dennis E. Doherty, M.D for the Lexington VAMC

Award period: 5-1-08 – 9-30-11 Total Award Budget: 50% FTE for Coordinator

50] Grant Number: Protocol #205.235

Title: A randomized double-blind placebo-controlled parallel group trial assessing the rate of decline of lung

function with tiotropium 18 Mcg capsule once daily in patients with COPD


Award Period: 9/1/02 – 6/30/09 Total Award Budget: $120,600

49] Grant Number: Protocol #PIPF-006

Revised 7/1/16


Title: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of the Safety and Efficacy of

Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis



48] Grant Number: Protocol MK-007-04

Title: A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Parallel Group, Dose-Ranging Study

of MK-0633 in Adult Patients with Chronic Asthma (With Optional Extension)



47] Grant Number: Protocol Merck 009-02

Title: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study, Conducted Under In-house

blinding Conditions of MK-0633 in Patients with COPD


Award Period: 11-1-08 to 6-30-09 Total Award budget: $ 61,500

46] Grant Number: Protocol QAB149B2335S

Title: A 26-Week Treatment, Multicenter, Randomized, Double-Blind, Plscebo-Controlled, Adaptive,

Seamless, Parellel-Group Study to Assess the Efficacy, Safety, and Tolerability of Two Doses of Indacaterol

(Selected from 75, 150, 300, 600 micrograms b.i.d.) in Patients with Chronic Obstructive Pulmonary Disease

Using Blinded Formoterol (12 micrograms b.i.d) and Open Label Tiotropium



45] Grant Number: Protocol #ADC105931

Title: A Randomized, Double-Blind, Parallel-Group, 12-week Study to Evaluate the Anti-Inflammatory

Effect pf Fluticasone propionate/Salmeterol DISKUS 25/50mcg BID Compared with Salmeterol DISKUS

50mcg BID in Subjects with COPD.



44] Grant Number: BY2001/M1-007

Title: Venticulate (rSP-C Surfactant) in patients with pneumonia or aspiration of gastric contents leading to

intubation, mechanical ventilation, and severe oxygenation impairment. A randomized multinational,

multicenter, parallel group, double blind, control group study

Principal Investigator: Dennis E. Doherty, MD


43] Grant Number: Protocol BY217/M2-111

Title: Effect of roflumilast on exacerbation rate in patients with chronic obstructive pulmonary disease



42] Grant Number: NIH RO1, NIH, NHLBI RO1 HL63800

Title: Molecular Pathways of Monocyte Survival

Co-Principal Investigator (Ohio State), Principal Investigator (Univ. Kentucky): Dennis E. Doherty, M.D.

Revised 7/1/16


Award Period: 7/1/00 - 6/30/05 Total Award Budget: $106,285

41] Grant Number: NIH K-30, Career Training in Therapeutics and Translational Research

Title: Understanding the Physician-Patient Relationship for Individuals with Asthma

Principal Investigator: Margaret M. Love, Ph.D.

Co-Principal Investigator/Mentor: Dennis E. Doherty, M.D.

Award Period: 3/1/01 – 6/30/05 Total Award Budget: $5000

40] Grant Number: Protocol #SCO30003

Title: A Multi-center Randomized Double-blind Parallel Group Placebo-controlled Study to Investigate the

Long-term Effects of Salmeterol/Fluticasone Propionate, Salmeterol and Fluticasone on the Survival of

Subjects with COPD over Three Years of treatment



39] Grant Number: Protocol BAMSG 2-01

Title: A randomized, double-masked trial of capsofungin verses placebo as prophylaxis of invasive

candidiasis in high-risk adults in the critical care setting


Award Period: 1/05 – 12/05 Total Award Budget: $$113,000

38] Grant Number: Protocol SCO40030

Title: A randomized, double-blind, placebo-controlled, parallel-group clinical trial evaluating the effect of

fluticasone propionate/salmeterol combination product 250/50mcg bid via Diskus and salmeterol

50mcg bid via Diskus on lung hyperinflation in subjects with chronic obstructive pulmonary disease

(COPD)



37] Grant Number: Protocol #SAS40026

Title: A Randomized Double-Blind, Parallel Group, Comparative Trial of Salmeterol/Fluticasone

Propionate Combination Product 50/100mcg Diskus Inhaler BID Verses Fluticasone Propionate

250mcg Diskus Inhaler BID IN Adolescents And Adults With Moderate Persistent Asthma




Title: A Comparison of Ipratropium bromide/salbutamol delivered by the Respimat inhaler to ipratropium

bromide Respimat, Combivent inhalation aerosol and placebo of each formulation in a 12 week

double-blind, safety and efficacy study in adults with COPD



35] Grant Number: Protocol #CFOR258D

Title: A randomized multi-center placebo-controlled parallel group study of four months duration per

Revised 7/1/16


patient to evaluate the safety and efficacy of treatment with 24ug bid and 12ug bid fomoterol, double-

blind and 12ug bid formoterol with additional on-demand formoterol doses open-label in adolescent and

adult patients with persistent stable asthma



34] Grant Number: Protocol NA17098

Title: A multi-center, randomized, double-blind, placebo-controlled Phase 2a dose-response study of the

safety, and tolerability, of two doses of RO3300074 given for 4 weeks to patients with moderate to

severe symptomatic emphysema



33] Grant Number: Protocol #FDP40014

Title: A Randomized Double-blind 12 week Comparative Trial of Fluticasone Propionate DISKUS verses

Fluticasone Propionate DISKUS and Oral Montelukast in Adults with Persistent Asthma



32] Grant Number: Protocol #

Title: A Randomized Double-blind Placebo-controlled Parallel Group Trial Assessing Proportion of Patients

Experiencing an Exacerbation and Proportion of Patients Hospitalized for an Exacerbation Over 6

Months During Treatment with Tiotropium Once Daily in Patients with COPD in a Veterans Affairs

Setting.



31] Grant Number: Microarray Facility Pilot Grant Program, University of Kentucky Medical Center

Title: Murine Gene Expression During Chronic Alcohol Ingestion


Award Period: April 2003 Total Award budget: $5,000

30] Grant Number: K30 HL04163

Title: Career Training in Therapeutics and Translational Research

Co-Principal Investigator: Dennis E. Doherty Principal Investigator: Robert Blouin, PharmD.

Award Period: 9/1/01 – 8/31/06 (Co-PI ended 4-30-03)

29] Grant Number: Protocol #SCO40011

Title: A Randomized Double-blind Double Dummy Parallel Group Comparative Clinical Trial Evaluating

Fluticasone Propionate/Salmeterol Xinafoate to Ipratropium Bromide/Albuterol Sulfate Inhalation

Aerosol in Patients with COPD


Award Period: 12/1/01- 12/31/03 Total Award Budget: $45,600

28] Grant Number: Veteran's Affairs Research Associate Award - Level II Career Development

Title: Adenovirus-Mediated Gene Therapy and Immuno-Modulation

Principal Investigator: Edward A. Hirschowitz, M.D.

Revised 7/1/16


Principal Mentor: Dennis E. Doherty, M.D.

Award Period: 1/1/99 - 12/31/01 Total Award Budget: $8/8 VA salary + $150,000

27] Grant Number: Protocol #GIPF-001

Title: A Randomized Double-Blind Placebo-controlled, Phase III Study of the Safety and Efficacy of

Subcutaneous Recombinent Interferon-gamma 1b in Patients with Idiopathic Pulmonary Fibrosis



26] Grant Number: Protocol SNG477/SMART Study

Title: SNG477/SMART Study




Title: A One-Year Randomized Double-Blind, Placebo and Active-Controlled Parallel Design Safety and

Efficacy Comparison of COMBIVENT HFA Inhalation Aerosol to COMBIVENT (CFC) inhalation

Aerosol in Patients With COPD



24] Grant Number: Protocol #091-021

Title: A Multi-Center, Randomized, Placebo and Active-Controlled, Five-Way Crossover Study of (R,R) -

Fomoterol Tartrate Inhalation Solution and Salmeterol In Subjects With Chronic Obstructive

Pulmonary Disease



23] Grant Number: Protocol #PR00-15-010

Title: A Prospective Multi-Center Study of the Anemia of Critical Illness and Transfusion in the Critically

Ill Patient

Principal Investigator: Dennis E. Doherty, M.D. Co-Principal Investigator: Rolando Berger, M.D.


22] Grant Number: Protocol 013-00 Period IV

Title: Validation of Outcome Measures for Chronic Obstructive Pulmonary Disease



21] Grant Number: Protocol EP07014.002

Title: Extension of A Double-Blind Randomized Placebo-Controlled Multicenter Parallel-Group Dose-

Ranging Study of L-753099



20] Grant Number: Protocol #3001K1-912-US

Title: A Randomized Open-Label, Pilot Assessment of the Effect of Protonix I.V. (Pantoprazole Sodium)

on Gastric pH in ICU Patients

Revised 7/1/16




19] Grant Number: Protocol L-753099

Title: A Double-Blind Randomized Placebo-Controlled Multicenter Parallel-Group Dose-Ranging

Study of L-753099



18] Grant: NIH: PO1 NS 31220-01A1 PPG Mechanisms of Brain Injury and its Systemic Sequelae

Title: Project 4-Mechanisms of Head Trauma-Induced Lung Injury



17] Grant Number: American Lung Association Clinical Research Grant (co-funded by Kentucky ALA)

Title: Anti-Inflammatory Effect of Azithromycin in Cystic Fibrosis

Principal Investigator: Michael I. Anstead, M.D.

Principal Mentor: Dennis E. Doherty, M.D.

Award Period: 7/1/98- 6/30/00 Total Award Budget: $48,950

16] Grant Number: American Lung Association Research Grant (funded by the Kentucky Association)

Title: Pulmonary Fibrosis: Macrophage-ICAM-1 Interactions



15] Grant Number: American Lung Association Research Grant (funded by the Kentucky Association)

Title: Pulmonary Fibrosis: Macrophage-ICAM-1 Interactions



14] Grant: Scintiprox, Inc

Title: Comparative Respiratory Deposition of 99mTC-Labeled Particles in Healthy Human Volunteers

Using Gamma Scintigraphy



13] Grant Number: Veteran's Administration Merit Review Award #002

Title: Monocyte-Endothelial Cell Interaction - Role of Lipopolysaccharide and TNF



12] Grant Number: HL27353 - NIH, NHLBI SCOR in Pathobiology of Fibrotic Lung Disease

Title: The Immune Reactivity in Experimental Lung Fibrosis

Co-Investigator: Dennis E. Doherty, M.D.


Left grant at National Jewish Center for Immunology when relocated to University of Kentucky

Revised 7/1/16


11] Grant Number: HL27353 - NIH, NHLBI SCOR in Pathobiology of Fibrotic Lung Disease

Title: Morphology Core A



Left grant at National Jewish Center for Immunology when relocated to University of Kentucky

10] Grant Number: Novo Nordisk A/C Denmark - Grant in Aid

Title: Heparin Binding Protein and Lung Inflammation



9] Grant Number :XOMA Corp.

Title: The Effects of BPI21 on Mechanisms of Regulating LPS-Induced Monocyte and Neutrophil

Accumulation in the Lung



8] Grant Number: HL27353 - NIH, NHLBI SCOR in Immunological and Occupational Lung Diseases

Title: The Fate of Mononuclear Phagocytes in the Lung: Project 3




Title: Idiopathic Pulmonary Fibrosis, Pathogenesis and Staging: Project 1

Principal Investigator: Talmadge King M.D. Co-Investigator: Dennis E. Doherty, M.D.


6] Grant Number: Veteran's Administration Clinical Investigator Award - Salary Grant

Title: Career Development Program


Award Period: 1/01/92 - 12/31/96 Total Award Budget: Salary Grant (8/8 VA)

5] Grant Number: 3M01RR00051-33S2 - NIH

Title: General Clinical Research Center: Protocol number - NJ 026

Principal Investigator: Richard Krugman, M.D. Co-Investigator: Dennis E. Doherty, M.D.

Total Award Period: 12/1/93 - 11/30/96 Total Grant Award Budget: $3,026,316

Award Budget for Protocol NJ 026 Dr. Doherty: $113,950

4] Grant Number: American Lung Association/American Lung Association of Colorado

Title: Monocyte Kinetics During Lung Inflammation



3] Grant Number: HL01804 - NIH, NHLBI Clinical Investigator Award

Title: Monocyte Kinetics and Adhesion During Lung Inflammation



Revised 7/1/16



Title: Fibroblasts and the Fibrotic Lung



1] Grant Number: Veteran's Administration Merit Review Award #001

Title: Monocyte-Endothelial Cell Interaction - The Effects of Lipopolysaccharides



B. Pending Grant Support

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