Dengue control
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Transcript of Dengue control
Controlling DengueRafi ur RahmanM. Phil (Biotechnology and Genetic Engineer)
Introduction:DengueCausative Agent, The VirusTransmissionThe MosquitoControl
The Dengue Fever Is an acute fever producing infectious
disease Mostly found in the tropics Pronounce DEN-ghee Complications can be fatal It is also known as Dengue fever , break-
bone fever. Complicated forms are DHF and DSS
Causative Agent: The Virus RNA Virus Genus Flavivirus. Family Flaviviridae. 11000bp which encodes a single large
poly protein. Other relatives: West-Nile virus, Yellow
fever virus, hepatitis C virus. Four Serotypes: DEN1-4. 60-80%
sequence homology and also Surface Protein Homology
Transmission: Aedes Aegypti: Cosmopolitan. Ae. Albopictus: South-East Asia. Biting around the ankles and knees close
to the ground in the daytime Distinct Physical Features. Life cycle.
The Mosquito: Dengue cases usually increase during
the rainy season The spread of the mosquito is attributed
to poor environmental sanitation When it rains the water gets stored in
any place such as discarded tires, broken bottles, and even shoes
Other examples are soda cans, birdbaths, rain gutters, toys, pool covers, tree stumps, and garbage cans.
More About the Causative Agent: Male feeds on plant nectar Female feeds on blood (Human, Animals,
Birds, Monkeys). Life Span: 14-21 days. Lays 300 eggs during her life span. The mosquito can travel up to 10 km.
Control: No specific vaccine or drug invented. Can be controlled by limiting 1) Eliminating the Mosquito vector and/or 2) Interrupting Human-vector Contact.THAT’S WHY; Clothing, that minimize skin exposure must be
used. Mosquito repellents. Mosquito nets. Don’t let clear water un-covered for more than
1 day. Put the cover on water container along with
cloth.
Contdd.. If the larvae are seen any where, put
some detergent(surf), wait for some time and then discard.
Do not leave any source into the water tanks(over-flow, air source), if left however, cover with some sort of net or long pipe.
Focus on neglected areas like water pots in bird cages etc..
Turn over all unused water containers.
Control: Control of Immature stages: Vector control: 1. Larviciding with
insecticides.2. Elimination of breeding sites Only Temephos, Permethrin, Bti, and Pyriproxyfen
are approved by WHO for use in drinking-water. Bti Toxins: Bacillus thuringiensis var.
israelensis (Bti), Bacillus Sphaericus (Bs). High larvicidal activity in mosquitoes. Should be used in Combinations: [BTi + Insecticide], [BTi + Copepods]: Excellent
results. Commercial Preparations: Liquid/Granular Preps
are available.
References: Akram, W., (n.d.). Aedes as a vector of Dengue: a possible threat to our lives.
Khwarzimig Science Society. University of Agriculture, Faisalabad. Retrieved April 19, 2010 from http://www.khwarzimic.org/takveen/dengue_kss.pdf
Bauman, R., (2006). Microbiology disease by systems. San Francisco , CA: Pearson Benjamin Cumming Publisher
Center for Disease Control and Prevention, (2009)Dengue epidemiology. Retrieved April 22, 2010 from http://www.cdc.gov/Dengue/epidemiology/index.htm
Center for Disease Control and Prevention, (2009). Other infectious disease related to travel, dengue fever (DF) and dengue hemorrhagic fever (DHF). Retrieved April 19, 2010 from http://wwwnc.cdc.gov/travel/yellowbook/2010/chapter-5/dengue-fever-dengue-hemorrhagic-fever.aspx
Center for Disease Control and Prevention, (2009). About CDC’s dengue branch. Retrieved April24, 2010 from http://www.cdc.gov/Dengue/about/index.html
Gubler, D.J., Clark, G.G., (1995)Dengue/dengue hemorrhagic fever: The emergence of a global health problem. Retrieved April 19, 2010 from ftp://ftp.cdc.gov/pub/EID/vol1no2/adobe/gubler.vol1no2.pdf
Gubler, D., (1998). Dengue and dengue hemorrhagic fever . Clinical Microbiology Reviews, July 1998, p.480-496. Retrieved April 24, 2010 from http:/www.cmr.asm.org/cgi/repreint/11/3/480
World Health Organization, (2009). Dengue and Dengue haemorrhagic fever. Retrieved April 19, 2010 from http://www.who.int/mediacentre/factsheets/fs117/en /
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