D wise overview
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© d-Wise 2013 April 13, 2023 Page 1
April 13, 2023
d-Wise Technologies, Inc. Systems | Standards | Data | Process
© d-Wise 2013 April 13, 2023 Page 2
Data and Process Optimization Servicesfor Life Sciences & Healthcare
• Systems Implementation• Systems Integration• Clinical Data Repositories• Metadata Repositories• Standards Implementation
• Data Warehouses• Metadata Solutions• Business Intelligence• Data Analytics• Predictive Modeling
© d-Wise 2013 April 13, 2023 Page 3
Background
Technology
Founded in 2003
Privately Held
Fortune 500 Customers
Offices in US, UK
© d-Wise 2013 April 13, 2023 Page 4
Core Competencies
Customized Technology Strategies
Implementing DataStandards
Integration of Clinical Systems
Delivering SAS Solutions
Aligning Technology and
Process
© d-Wise 2013 April 13, 2023 Page 5
Expertise
Domain
Solution
Technology
SAS
• Clinical data flow, from collection to submission• Clinical Data Standards• Clinical Systems landscape
• Data Warehousing• Business Intelligence•Analytics and Reporting
• Commercial Software• Open Source• N-Tier Architechture
• Life Sciences Applications• Data Integration, Business Intelligence, Analytics• Validated SAS computing environment
© d-Wise 2013 April 13, 2023 Page 6
Life Science Practice Unique combination of life sciences and
technology experience to understand both your business process and technology challenges.
Experience with clinical data warehousing, programming, analytics and FDA submissions.
Extensive knowledge of CDISC, HL7 and other industry standards.
Experience planning, managing and delivering clinical trials.
Broad experience aligning strategic and tactical plans to help organizations address the challenges of technology adoption.
© d-Wise 2013 April 13, 2023 Page 7
Healthcare Practice Experience in data warehousing,
analytic data marts, actuarial analysis, quality reporting, and physician profiling
Experience with all aspects of health insurance including claims, members, providers, benefits, contracts, and rates
Management expertise in large-scale process improvement initiatives in the health insurance arena
© d-Wise 2013 April 13, 2023 Page 8
Our Data Architects Have broad experience applying data warehousing domain expertise to build
robust models for decision support. Our team can transform data warehousing from a contentious challenge to a value delivering asset.
Use a data-driven requirements gathering process comprehensively addressing the needs of the business users, IT, and enterprise architectures.
Use a technology agnostic approach that ensures the right solution for our client’s unique needs.
Have a deep expertise in data integration and ETL to build reusable modules. Follow best practices definition to define platforms to help your data
managers focus on the data rather than the tools. Metadata driven data management approach streamlines interfaces and
captures the right data about your data. Define warehouse models for integrating disparate operational data sources
for enterprise needs.
© d-Wise 2013 April 13, 2023 Page 9
We’ll Tackle Your Challenges
d-Wise will help tackle your business challenges by…
Offering a unique combination of software development and industry knowledge
Providing the expertise in a broad range of technologies to find the optimal solution
Having a successful track record of building the right solution for your problem
© d-Wise 2013 April 13, 2023 Page 10
What is Our Technical Expertise?
Extensive knowledge of data warehousing and business intelligence solutions
Broad range of experience with many different technologies
Unique software development perspective Decades of experience developing and implementing
SAS-specific solutions
© d-Wise 2013 April 13, 2023 Page 11
Data Warehousing Experience
Experience with the design and development of large scale data warehouses
Data modeling to optimize the flow of data Experience with both relational and non-relational
databases Experience with leveraging industry standards to
optimize your technology Experience integrating a range of products including
JReview, WinNonLin, Oracle Clinical, DS Navigator and home grown data warehouses
© d-Wise 2013 April 13, 2023 Page 12
Data Warehousing Projects
d-Wise developed an integration interface for a top pharmaceutical company to streamline data across their disparate solutions
d-Wise designed and developed an enterprise toxicology data warehouse populated with data from over a dozen diverse sources
© d-Wise 2013 April 13, 2023 Page 13
Business Intelligence Experience
Integration of company’s technology to improve the flow of information
Development of custom reporting tools on top of existing solutions
Design and development of robust web based solutions for reporting and analytics
© d-Wise 2013 April 13, 2023 Page 14
Business Intelligence Projects
Developed a large scale web based quality control system for over 3000 laboratory sites
Managed a full scale project to develop a health insurance automation reporting solution using a range of different technologies
Implemented a enterprise portal solution for a large life science company including the development of standard dynamic reports
© d-Wise 2013 April 13, 2023 Page 15
Delivering SAS Solutions
Decades of design and development of core SAS products
Experience implementing SAS solutions in large companies
Ability to develop custom plug ins to existing SAS technologies
Experience using SAS as a customer Unique ability to assess current SAS architecture
and provide plan to meet strategic vision
© d-Wise 2013 April 13, 2023 Page 16
Delivery of SAS Solutions
Installation and implementation of SAS solutions including:
SAS Business Intelligence SAS Data Integration (Metadata Server and Data
Integration Studio) SAS Drug Development SAS Analytics Pro (BASE SAS, SAS/STAT, and
SAS/GRAPH) Implementation of Analysis tools including
Enterprise Guide, JMP, and Web Analytics
© d-Wise 2013 April 13, 2023 Page 17
Extending the Capabilities of SDD
Analytical Workflows – automate the “smart” extract and staging of data for analysis by statistical tools and publish/capture the results back into SDD
Loading Large Data – a plug-in to compress and package directories of data for quick upload, then to decompress and recreate the folder structure within SDD
Loads Incremental Data – a workflow for loading incremental data into SDD and maintaining concurrency between the source system and the SDD repository
© d-Wise 2013 April 13, 2023 Page 18
Extending SDD: Managing an Analytical Workflow
Analytics propel the drug discovery process Analytic processes:
– are fed by clinical data– produce data and metadata– are critical to the overall process
Computational requirements may prescribe a dedicated system beyond your repository
How can this specialized system be integrated with the repository?
© d-Wise 2013 April 13, 2023 Page 19
Managing Analytical WorkflowThe Solution
SAS Drug Development
Capture and
Select input data with subset criteria
(metadata driven)
Perform smart extract (just what you need)
ComputePublish computational
results and (using just-in-time data)
Metadata about the analysis
Analytic System
© d-Wise 2013 April 13, 2023 Page 20
Extending SDD: Challenges of Loading Data
Customer outsources all data and reporting activities to CROs
CRO produce multiple folders containing lots of data – data that must be loaded into SDD
– Loading this large volume of data is tedious & time consuming compared to loading a zipped archive
How can SDD support zipped archives?
© d-Wise 2013 April 13, 2023 Page 21
Challenges of Lots of FilesThe Solution
FIRE W
ALL
ROI: Reduced a 4 Hour Process to 15 Minutes
SAS Drug Development
© d-Wise 2013 April 13, 2023 Page 22
Study Data Lifecycle: Challenges of Incremental Loads
Customer environment includes a local CDR and a SAS hosted SDD
Frequent, but minor, updates to large studies result in customer pains– Significant network traffic– Long upload times– Users waiting while data is extracted and uploaded
Would incremental uploads be faster?
© d-Wise 2013 April 13, 2023 Page 23
Challenges of Incremental Data The Solution
SAS Extract
Callback Program
Merge Data (ODM, CSV,
SAS)FIR
E W
ALL
SAS Drug Development
SAS Merge
ROI: Reduced a 12+ Hour Uploads to Minutes
© d-Wise 2013 April 13, 2023 Page 24
How is this possible?
d-Wise thinks about SDD as a platform Integrating remote systems can be made simple –
clients can be introduced locally or remotely… depending on the needs
What is the role of an API? Where do web services fit into this puzzle? How does all this techno-speak translate into
something valuable for the business?
© d-Wise 2013 April 13, 2023 Page 25
Thinking about the possibilities.
As a platform, SDD can be extended to bring new capabilities to the business
Extending doesn’t have to mean customizing – plug-ins can sit next to SDD without compromising the integrity, security, or compliance of the underlying system
Workflow and automation specialized for your approach to data management – SDD makes this possible through the API
© d-Wise 2013 April 13, 2023 Page 26
Integrating SDD with a Clinical Data Repository
SAS Extract
Callback Program
Merge Data (ODM, CSV,
SAS)
FIRE W
ALL
SAS Drug Development
SAS Merge
ROI: Reduced a 12+ Hour Uploads to Minutes
© d-Wise 2013 April 13, 2023 Page 27
d-Wise CustomersBioTechnology / Pharmaceutical
Education Other
Health Care