Curriculum Vitae ANDREADIS DIMITRIOS, DDS, PhD, Assistant ... › cv.pdf · 1. Senior Lecturer in...

Andreadis D, Curriculum Vitae 2015

1

CurriculumVitae

ANDREADISDIMITRIOS,DDS,PhD,

AssistantProfessorinOralMedicine/Pathology

I.BriefOverview

CurrentPosition:• AssistantProfessor,Dept.ofOralMedicine/Pathology,SchoolofDentistry,AristotleUniversityofThessaloniki,GR-54124,Thessaloniki,Greece,

Tel:+302310999540,Fax:+302310999531,e-mail:[email protected]• VisitingResearchFellow,DepartmentofConservativeDentistry,PeriodontologyandPreventiveDentistry,MedicalUniversityofHannover,D-30625,

Hannover,Germany,Tel:+495115324862,Fax:+495115324815• PrivateDentalPracticeexclusivelyonOralMedicine/Pathology

• DATEOFBIRTH:15thMars1974CurrentClinicalandResearchInterests:

• Diagnosis(ClinicalandMicroscopic)ofOralDiseases• Salivary/Oralmucosal/OralcancerStemCellBiology• Diagnostic&ClinicopathologicStudiesonHPVinOralDiseases• ImmunohistochemistryonOralCancerandImmune-RelatedMucocutaneousDiseases


2

Sixmostimportantpublications/presentationsrelatedtocurrentresearchinterests:

1. BakopoulouA,KritisA,AndreadisD,PapachristouE,LeyhausenG,KoidisP,GeurtsenW,TsiftsoglouA.Angiogenicpotentialandsecretomeofhumanapicalpapillamesenchymalstemcellsinvariousstressmicroenvironments(submittedtoStemCellsandDevelopmentforpeer-review)

2. AndreadisD, BakopoulouA, LeyhausenG, EpivatianosA, Volk J,MarkopoulosA,GeurtsenW.Minor salivary glands of the lips: a nove easilyaccessiblesourceofpotentialstem/progenitorcells.ClinOralInvest2014;18(3):847-856

3. KyrodimouM,Andreadis D, Drougou A, Amanatiadou EP, Angelis L, Barbatis C, Epivatianos A, Vizirianakis IS. Desmoglein-3/γ-catenin and E-cadherin/ß-catenindifferentialexpressioninoralleukoplakiaandsquamouscellcarcinomaClinOralInvest.2014;18(1):199-210

4. KehagiasN,EpivatianosA,SakasL,AndreadisD,MarkopoulosA,AntoniadesK.ExpressionofN-cadherininsalivaryglandtumorsMedPrincPract.2013;22(1):59-64

5. AndreadisD,Albanidou-FarmakiE,PoulopoulosA,KatsaresV,ParapanisiouE,MarkopoulosA. Cytokines’genepolymorphismsinoralmucousmembranepemphigoid.OralDis2014;20(2):9

6. PoulopoulosA,KarakitsosG,HempelM,AndreadisD,MarkopoulosA,GonshorA.AssessmentofHPVinoralleukoplakiautilizingascreeningtest.46thMeetingoftheContinentalEuropeanDivision(CED)ofIADR,4-7/9/2013,Florence,Italy

• TotalNumberofPublishedArticles&AbstractsinPeerReviewedJournals:37&15• PresentationsinInternationalMeetings(withpeer-reviewingprocessing):42• PresentationsinNationalMeetings:84• ContributionstoBooks:2• TotalNumberofCitations:182(source:SCOPUS)• h-index:8• Totalimpactfactor(PUBLICATEDMANUSCRIPTS&ABSTRACTS):33817&34931

ü ReviewerinScientificJournals:Morethan10internationalpeer-reviewjournalsü Editor:MedOralPatolOralCirBucal(IF=1130)ü SupervisionofMasterThesis(2009-2015):morethan10ü ParticipationinEvaluationcommitteeofPhDThesis:1


3

I.AnalyticalInformationPREVIOUSPOSITION

1. SeniorLecturerinOralMedicine/Pathology,Dept.ofOralMedicine/Pathology,SchoolofDentistry,AristotleUniversityofThessaloniki(2009-2015)

2. ClinicalAssistantinOralMedicineUnit,DermatologyClinic,“A.Sygros”Hospital,SchoolofMedicine,NationalandKapodestrianUniversityofAthens,

Greece(Head:ProfLaskaris)(2005-2007)

BASICEDUCATION

1. 1999-2004:PhDinOralPathology,DepartmentofOralMedicine/Pathology,SchoolofDentistry,AristotleUniversityofThessaloniki,Greece

Thesis: “Expression of cell adhesion molecules in salivary gland neoplasms”, grade: “Excellent”. PhD program was funded by the Greek State

ScholarshipFoundation(Ι.Κ.Υ.):ScholarshipinOralPathobiology(1999-2003)

2. 1998-2000: Postgraduate educational program inOralMedicine/Pathology:Department of OralMedicine/Pathology, School of Dentistry, Aristotle

UniversityofThessaloniki,Greece,Dissertation:“Odontogenictumours”

3. 1992-1998:DiplomaofDentalSurgeon(DDS),SchoolofDentistry,AristotleUniversityofThessaloniki,Greece,grade:7/10

CONTINUINGEDUCATION(CLINICAL–RESEARCH)&FUNDINGPROGRAMS

1. 16/8/2013-20/10/2013:3-monthResearchProjectfundedbyDAAD(DeutscherAkademischerAustauschDienst-GermanAcademicExchangeService)


4

ScientificField:Minor salivaryglandStem/Progenitor cellsbiology. LaboratoryofMolecularBiology,DepartmentofPeriodontology,Preventiveand

ConservativeDentistry,FacultyofDentistry,HannoverSchoolofMedicine,Germany (MedizinischeHochschuleHannover,Germany) (Professorand

Head:ProfW.Geurtsen)

2. 22/7/2011 – 15/8/2011 Life Long Learning Program, Erasmus Staff Training: Laboratory of Molecular Biology, Department of Periodontology,

PreventiveandConservativeDentistry,FacultyofDentistry,HannoverSchoolofMedicine,Germany(MedizinischeHochschuleHannover,Germany)

(ProfessorandHead:ProfW.Geurtsen)

Scientific Fields: Stem/Progenitor cell cultures, culture media and relevant molecular methods (Flow Cytometry, Western Blot, PCR) for their

characterization

3. 2005 – 2007: Clinical Assistant in Oral Medicine Unit, Dermatology Clinic, “A. Sygros” Hospital, School of Medicine, National and Kapodestrian

UniversityofAthens,Greece(Head:Ass.ProfG.Laskaris)

ScientificField:OralMedicine:DiagnosisandTreatmentofOralDiseases

4. 2003-2005:DepartmentofPathology(Histopathology),RedCrossHospitalofAthens,Greece(Head:DrC.Barbatis,MD,MSc,PhD,FRCPATH)

38.Scientific Fields: Oral Pathology: Salivary gland tumors and Squamous Cell Carcinoma histopathology, Immunohistochemistry, Image Analysis &

MorphometricforOpticalMicroscope

5. 10/2002–3/2003:LaboratoryofBiopathology,StateHospital forSkinandVenerealDiseases,Thessaloniki,Greece(Head:DrO.Mourellou-Tsatsou,

MD,PhD)

ScientificFields:Αντικείμενο:ELISAmethod

1. Title:Isolation&characterizationofprogenitor/stemcellculturederivedfromminorsalivaryglands

RESEARCH(projects)


5

Inco-operationwiththeLaboratoryofMolecularBiology,DepartmentofPeriodontology,PreventiveandConservativeDentistry,FacultyofDentistry,

HannoverSchoolofMedicine,Germany(MedizinischeHochschuleHannover,Germany)(ProfessorandHead:ProfW.Geurtsen)

FundedbyDAAD(DeutscherAkademischerAustauschDienst-GermanAcademicExchangeService)

2. Title: IL1α, ΙL1β, ILR, IL1Rα, IL2, IL4, IL6, IL10, IL12, IFN-γ, TNFα, TGFb Cytokines’ gene polymorphisms in Oral Lichen Planus and oral Mucous

MembranePemphigoid

FundedbytheResearchCommitteeofAristotleUniversityofThessaloniki(88128ActionΑ)

Inco-operationwiththeDepartmentofImmunologyandHistocompatibility,“Hippokrateion”HospitalofThessaloniki,Greece

3. Title:Expressionofcadherinsandcateninsinvitroandintissuespecimensfromoraldysplasiaandsquamouscellcarcinoma

Inco-operationwiththeDepartmentofPharmacology,SchoolofPharmaceuticalSciences,AristotleUniversityofThessalonikiandtheDepartmentof

Pathology(Histopathology),RedCrossHospitalofAthens,Greece

4. Title:PemphigusVulgarisanti-desmoglein-3&1andBullousPemphigoidanti-BP180autoantibodiesinsalivausingELISAmethod

ThisprojectwasfundedbytheDepartmentofOdontostomatologicalScience,UniversityofSiena,Italy)andwascarriedoutinco-operationwiththe

LaboratoryofBiopathology,StateHospitalforSkinandVenerealDiseases,Thessaloniki,Greece.

5. Title:ExpressionofCD117(C-KIT)inbenignandmalignantsalivaryglandtumors

Inco-operationwiththeDepartmentofPathology(Histopathology),RedCrossHospitalofAthens,Greece

Participationinresearchprojects-ongoing:1. DETECTIONOFHPVINORALDISEASESUSINGBRUSHMETHODS

2. INVITROBUCCALDRUGDELIVERYOFDRUGSINTHEPRESENCEOFPERMEATIONENHANCERS:THEEFFECTOFCHARGE(LaboratoryofPharmaceutical

Technology,DepartmentofPharmaceuticalSciences,AristotleUniversityofThessaloniki,GR-54124Thessaloniki,Greece)


6

MEMBERSHIPININTERNATIONALPROFESSIONALANDSCIENTIFICSOCIETIES

• EuropeanAssociationofOralMedicine(EAOM)(2006-present)

• InternationalAssociationofOralPathology(2013-present)

• InternationalAssociationforDentalResearch(2009-present)

• EuropeanCellDeathOrganisation(ECDO)(2004-2005)

ACADEMICACTIVITY

TEACHINGEXPERIENCE(2009-2013)

TeachingExperience:Since2009Iamaclinicalsupervisorofthe4thand5thyearundergraduateaswellasandpostgraduatestudentsofthe3-yearPostgraduatePrograminOral

Medicine/Pathology.Inaddition,togetherwithotherstuffIamresponsiblefortheclinicalandthehistologicalserviceforoutpatientsoftheDepartment

including clinical diagnosis, biopsies’ uptake etc. In addition, I am participating in the program of lectures concerning both Oral Medicine and Oral

Pathology, in thecontextofseveralcoursesof theundergraduateandpostgraduateprogram.Also, Iamsupervisor/co-supervisororparticipating in the

evaluationofseveralMasterandonePhDThesisasaSeniorLecturerandAssociateProfessor.

• Α.UNDERGRADUATETEACHINGü 4thyearundergraduatestudents:Signs&SymptomsinOralDiagnosis,Oralmanifestationsofdrugsideeffects),ReactiveOvergrowthlesionsof

oralmucosa,Developmentaldisordersandsyndromesofheadandneck,Salivaryglandnon-neoplasticdiseases,Oralmucosa inflammatorydiseases (Mechanical and Chemical), Saliva (Secretion, characteristics, role), Oral Pathology (Histology, Microscopy of oral diseases) OralPhysiology


7

ü 5th year undergraduate students: Clinical education and selected lectures onOralMedicine/Pathology including:Oral Cancer, Autoimmunediseases,Systemicdiseasesandoralmucosa

• Β.POSTGRADUATETEACHING(3-yearprogram)

ü OralMedicine:Saliva:secretionandrole,Granulartumors,OralGranulomatosis,Giantcellslesions,Leukemias-Lymphoproliferativeblooddisordersandgammopathies,Immunopathologyofimmune-relateddiseases,Oralmanifestationsofdrugssideeffects

ü OralPathology:OralHistologyandPhysiology,Salivaryglandsanatomyandstructure,Oralepithelialpathology,LaboratorycourseStains(hematoxylin-eosinandimmunohistochemistry),Salivaryglandnon-neoplasticdiseasesSalivaryglandtumors,Clinical-MicroscopicStaging,Molecularbiologyandpathogenicmechanismsinoralcancer,OralStemCells

ParticipationinMater’sthesessupervision(2009-2014)(yearofcompletionisreferredinparenthesis)

DimitriouA.ImmunohistochemicalexpressionofTGF-binSjogrensyndrome(2014-present)

ParcharidisE.AssessmentofHPVinoralmucosaofwomenwithHPV+detectioningenitalmucosa.(2014-present)

Chatzisymeonidou S. Clinical-Statistical analysis of Desquamative gingivitis. (Supervisors: Prof Markopoulos A, Ass. Prof Poulopoulos A, Lecturer

AndreadisD)(2015)

KiriliT.InvitrostudyofSisterChromatidExchangeinperipherallymphocytesinorallichenplanus.Supervisors:Ass.ProfPoulopoulosA,EmeritusProf

MourelatosD,LecturerAndreadisD)(2009-present)

KarakoulakiS. Investigationof therelationshipbetweenstressandbruxism.Evaluationofstresswith theuseofsalivarybiomarkers (cortisolanda-

amylase)(ProfKoidisP,AssProfTortopidisD,LecturerAndreadisD)(2012).

PapadopoulosP.Pappiliformoraldiseases.(Supervisors:ProfKolokotronisA,ProfEpivatianosA,LecturerAndreadisD)(2012)

ZorbaM.Giantcelllesionsoforalmucosa.(Supervisors:EpivatianosA,Ass.ProfPoulopoulosA,LecturerAndreadisD)(2012)

IordanidouH.Gustatorydisorders.(Supervisors:AssProfLink-TsatsouliI,AssProfAlbanidou-FarmakiH,LecturerAndreadisD)(2012)


8

KounoupisB.OralHemangiomas(Supervisors:ProfKolokotronisA,LecturerAndreadisD,AssProfPoulopoulosA)(2011)

KyrodimouM.Studyofgeneandproteinalterationsofcelladhesionmoleculesinoralsquamouscellcarcinoma.(Supervisors:AssProfVizirianakisI,

LecturerAndreadisD,AssProfPapadopoulouL)(2010)

KittasD.Clinical-Statisticalanalysisoforallichenplanus.(Supervisors:ProfMarkopoulosA,LecturerAndreadisD,AssProfAlbanidou-FarmakiH)(2010)

Sakaloglou E. Head and Neck tumors in children and adolescence. Review of the Literature. (Supervisors: ProfMarkopoulos A, Ass Prof BelaziM,

LecturerAndreadisD)(2010)

PanagiotidouT.Clinical-StatisticalanalysisofSjögrensyndrome.(Supervisors:ProfKolokotronisA,AssProfPoulopoulosA,LecturerAndreadisD)(2010)

BOOKCHAPTERS’AUTHORSHIPS

• Mosby’sDictionary,inGreekLanguage,2ndEdition,MendorEditionsS.A.2009

• AcademicBookChapter:Drugssideeffectrelatedoralmanifestations.FortheCourse:Signs&SymptomsinOralDiagnosis(100502C)

AWARDS

• *Andreadis D, Albanidou-Farmaki E, Deligiannidis A, Katsares V, Farmakis K, Poulopoulos A, Markopoulos A, Parapanisiou E, Epivatianos A.

Cytokines’ gene polymorphisms in oral lichen planus. 11th Biennial Congress of the European Association ofOralMedicine, Athens, Greece 15-

17/9/2012.Thisabstractwashighlyscoredandselectedforanoralposterpresentation,participatinginEAOMprizes’competition.

• AndreadisD,NomikosA, TsamouriM,VlachouE,GionisC,AntoniadisD, KapoulaP, KefalaM,PapazoglouG,Barbatis C. Immunohistochemical

study of the expression of cell adhesion molecules b4-integrin, E-cadherin, Desmoglein-2, ICAM-1, CD44s in normal salivary glands. (poster

presentationinGreek).Thispresentationwasawardedinthe9thHellenicCongressofPathology,Kavala,20-24/6/2004


9

• AndreadisD,MarkopoulosA.Thepsychologicalprofileofpatientswithoralcancer.GreekJOralMaxillofacSurg2001;16:27-35(Reviewpublication

inGreek).TheEnglishversionoftheabstractofthismanuscriptwasselectedforre-publicationas:AndreadisDA,MarkopoulosA:Thepsychological

profileofpatientswithoralcancer.(Summary).MundKieferGesichtsChir2001;(5):209-210

INVITEDREVIEWER

1. EuropeanJournalofDermatology&Venereology(JEADV)(IF=2980)2. VirchowsArchiv(IF=2491)3. Histology&Histopathology(IF=2480)4. Pathology(IF=2378)5. JournalofClinicalPathology(JCP)(IF=2306)6. ΑrchivesofOralBiology(AOB)(IF=1772)7. OMICSGroupJournalofClinical&ExperimentalDermatology(IF=1198)8. MedOralPatolOralCirBucal(IF=1130)9. JournalofCancerResearchandTherapeutics(IF=656)10. GreekJOralMaxFacSurg

OTHER

1. RefereefortheGreekStateScholarshipFoundation(2012-2013)

2. MemberofEditorialBoard:MedOralPatolOralCirBucal(IF=1130)

3. EnglishLanguage(Verywell)


10

SOCIALACTIVITY

1. Speaker representing theDentalSchoolofAUTHat theeventsorganizedby theOffice forProfessionalOrientationof theAristotleUniversityof

Thessaloniki incollaborationwith theCenters forCounselingandGuidance (KE.SY.P)of theAdministrationofSecondaryEducationofEastern&

WesternThessalonikiaddressedtohigh-schoolstudentson'StudiesattheAristotleUniversityofThessaloniki'withthetopic:AndreadisD.Dental

Science:ScienceofHealthOral&Tooth,"ScienceofMetamorphosis."Thessaloniki,22-25/2/2013,25/1/2012,28/2/2011,22-25/2/2010.

2. PublicationsinaGreeknon-scientificjournal:

• Andreadis D. Chronic Renal failure/transplantation and oral health. Part A: Oral manifestation in patients with chronic renal failure.

«Dromeas»Journalofpatientswithchronicrenalfailureandrenal(kidney)transplantation2010;6:16-17(articleinGreek)

• Andreadis D. Chronic Renal failure/transplantation and oral health. Part B: Oral manifestation in patients with renal (kidney)

transplantation.«Dromeas»Journalofpatientswithchronicrenalfailureandrenal(kidney)transplantation2010;7:16-17(articleinGreek)

3. Since2010,IamanAthlete/TeamManageroftheGreeceNationalTeamofDialysisandRenal(Kidney)TransplantedPatientsandIamparticipating

intheGAMESorganizedbytheEuropeanandWorldFederationofSportsforPeoplewithDialysisandOrganTransplantation(heldinDublinIreland

2010,Gothenburg-Sweden2011,Zagreb-Croatia2012).


11

ListofPUBLICATIONS&PRESENTATIONS

Α/Α PUBLICATIONSININTERNATIONALJOURNALS

1. Bakopoulou A, Kritis A, Andreadis D, Papachristou E, Leyhausen G, Koidis P, Geurtsen W, Tsiftsoglou A. Angiogenic Potential and Secretome of Human Apical Papilla Mesenchymal Stem Cells in Various Stress Microenvironments. Stem Cells Dev 2015;24(21):2496-512

2. KarakoulakiS,TortopidisD,AndreadisD,KoidisP.Relationshipbetweensleepbruxismandstressdeterminedbysalivabiomarkers.IntJProsth2015;28(5):467-474

3. Dalampiras S, Andreadis D, Kostopoulos I, Stylianou F, Papadiochos I, Poulopoulos A. Excessive tongue amyloidosis as the diagnostic sign of multiple myeloma: a case report. Balk J Dent Med 2015;19:50-52

4. Zormpa M, Andreadis D, Poulopoulos A, Epivatianos A. Analysis of the histopathological features of 54 cases of peripheral giant cell granuloma. A retrospective study. J Stomat Occ Med, 2014;7(2) DOI 10.1007/s12548-014-0108-0

5. Andreadis D, Asimaki A, Albanidou-Farmaki E, Markopoulos A. Solitary angiokeratoma of the buccal mucosa. Report of a case. Balkan J Dent Med, 2014 (accepted for publication)

6. AndreadisD,BakopoulouA,LeyhausenG,EpivatianosA,VolkJ,MarkopoulosA,GeurtsenW.Minorsalivaryglandsofthelips:anoveeasilyaccessiblesourceofpotentialstem/progenitorcells.ClinOralInvest2014;18(3):847-856

7. Poulopoulos AK, Andreadis D, Markopoulos AK. Expression of matrix metalloproteinases 9 and 12 in actinic cheilitis. World J Exp Med2013;3(3):43-49

8. Andreadis D, Stylianou F, Link-Tsatsouli I, Markopoulos A. Bilateral masseter and internal pterygoid muscle hypertrophy: a diagnosticchallenge.MedPrincPract2014;23(3):286-288

9. Albanidou–FarmakiE,AndreadisD,PoulopoulosA,FarmakisK,MarkopoulosA.Serum levelsofHeat-ShockProtein-70 inpatientswithorallichenplanus.BalkanJDentMed2014;18:106-108

10. Epivatianos A, Andreadis D, Iordanidis S. Myofibroblasts and Transforming Growth Factor-Beta1 in reactive gingival overgrowths. J OralMaxillofacRes2013;4(1):e3

11. Georgakopoulou EA, Andreadis D, Arvanitidis E, Loumou P. Biologic agents and oral diseases-An update on clinical applications. ACTADermatovenerolCroat2013;21(1):25-35

12. KyrodimouM*,AndreadisD*,DrougouA,AmanatiadouEP,AngelisL,BarbatisC,EpivatianosA,VizirianakisIS.Desmoglein-3/γ-cateninandE-cadherin/ß-catenin differential expression in oral leukoplakia and squamous cell carcinoma Clin Oral Invest. 2014 Jan;18(1):199-210. doi:


12

10.1007/s00784-013-0937-z. Epub 2013 Feb 22.Feb22(inpress)(*equallycontributingfirstauthors)13. KehagiasN,EpivatianosA,SakasL,AndreadisD,MarkopoulosA,AntoniadesK.ExpressionofN-cadherin insalivaryglandtumorsMedPrinc

Pract.2013;22(1):59-64

14. DalampirasS,AndreadisD,EpivatianosA,SakasL,StankoP:PleomorphicAdenomaof theSublingualSalivaryGland:AnUnusualDiagnosticChallenge.MedPrincPract2012;21(3):282-284(

15. Kollia K, Kambouris ME, Belazi M, Koussidou-Eremondi T,Andreadis D, Velegraki A. Clinical-oriented polyphasic identification, typing andsusceptibilitymethodologyforCandidarugosaisolatestoestablishpotentialvirulencemarkersandprocessingguidelines.E–JournalofScience&Technology(e-JST).2012;1(7):43-54

16. AndreadisD,EpivatianosA,SamaraA,KiriliT,IordanidisF,PoulopoulosA.MyofibromaoftheOralMucosa:ACaseReport.MedPrincPract.2012;21(3):288-291

17. Andreadis D, Mauroudis S, Poulopoulos A, Markopoulos A, Epivatianos A. Lip Ulceration Associated with Intravenous Administration ofZoledronicAcid:ReportofaCase.HeadNeckPathol.2012;6(2):275-278

18. EpivatianosA,IordanidisF,AndreadisD,IordanidisS,PoulopoulosA,MarkopoulosA.Tenascin-CinchronicsclerosingsialadenitisHeadNeckPathol.2011;5(3):221-225

19. AndreadisD, PoulopoulosA,PapadopoulosP,EpivatianosA Localized tongueAmyloidosis inaPatientwithNeurofibromatosis type IIHeadNeckPathol.2011;5(3):302-305.

20. EpivatianosA, Iordanidis F,AndreadisD,MarkopoulosA, SamaraA.Myofibroblasts inmucoceles and chronic sialadenitis ofminor salivaryglands.Hippokratia2011;15(4):382-383

21. ArvanitidisE,AndreadisP,AndreadisD,BelaziM,EpivatianosA.Reviewingtheoralcarcinogenicprocess:keygeneticevents,growthfactorsandmolecularsignallingpathways.JBiolRes2011;16:313-336

22. AndreadisD,NomikosA,BarbatisC.MetastaticRenalClearCellCarcinomainparotidgland:Astudyofimmunohistochemicalprofileandcelladhesionmolecules(CAMs)expressionintwocases.PatholOncolRes2007;13(2):161-165

23. AndreadisD,GagariE,LaskarisG,KapsokefalosP. IdiopathicSweet’ssyndromewithoralmanifestations.Reportofacaseandreviewoftheliterature.ActaStomatologicaCroatica2007;41(2):152-158

24. EpivatianosA,PoulopoulosA,DimitrakopoulosI,AndreadisD,NomikosA,VlachouS,PapazoglouG,BarbatisC.Applicationofa-smoothmuscleactin and C-KIT in the differential diagnosis of adenoid cystic carcinoma from polymorphous low-grade adenocarcinoma. Oral Oncology2007;43(1):67-76


13

25. Andreadis D, Lorenzini G, Drakoulakos D, Belazi M, Mihailidou E, Velkos G, Mourellou-Tsatsou O, Antoniades D. Detection of pemphigusdesmoglein 1 and 3 autoantibodies and pemphigoid BP180 autoantibodies in saliva and comparison with serum values. Eur J Oral Sci2006;114(5):374-380

26. Andreadis D, Epivatianos A, Mireas G, Nomikos A, Poulopoulos A, Yiotakis J, Barbatis C. Immunohistochemical detection of E-cadherin incertaintypesofsalivaryglandtumors.JLaryngolOtol2006;120:298-304

27. AndreadisD,EpivatianosA,PoulopoulosA,NomikosA,ChristidisK,BarbatisC.Carcinosarcomaofparotid.Immunohistochemicalanalysiswithemphasisincellcyclemitoticactivityandcelladhesionmoleculesexpression.OralOncolEXTRA2006;42:140-143

28. AndreadisD,NomikosA,PoulopoulosA,EpivatianosA,BarbatisC.Diagnosisofametastaticmalignantmelanomainparotidgland.Reportofacase.OralOncolEXTRA2006;42:137-139

29. AntoniadesD,MarkopoulosA,AndreadisD,BalaskasI,PatrikalouE,GrekasD.Ulcerativeuremicstomatitisassociatedwithuntreatedchronicrenalfailure:reportofacaseandreviewoftheliterature.OralSurgOralMedOralPatholOralRadiolEndod2006;101(5):608-613

30. Antoniades DZ, Markopoulos AK, Deligianni E, Andreadis D. Bilateral aplasia of parotid glands correlated with accessory parotid tissue. JLaryngolOtol2006;120:327-329

31. AndreadisD,EpivatianosA,PoulopoulosA,NomikosA,PapazoglouG,AntoniadesD,BarbatisC.DetectionofC-KIT(CD117)moleculeinbenignandmalignantsalivaryglandtumours.OralOncol.2006;42(1):57-65

32. ΑndreadisD,NomikosA,EpivatianosA,PoulopoulosA,BarbatisC.BasaloidSquamousCarcinomaversusBasalCellAdenocarcinomaoftheoralcavity.Pathology2005;37(6):560-563

33. AndreadisD,EpivatianosA,PoulopoulosA,NomikosA,ChristidisK,PapazoglouG,AntoniadesD,BarbatisC.ImmunohistochemicaldetectionoftheexpressionofthecelladhesionmoleculesE-cadherin,desmoglein-2,beta4-integrin,ICAM-1andHCAM(CD44s)inWarthin'stumouroftheparotidgland.OralOncol.2005;41(8):799-805

34. PoulopoulosA,AndreadisD,EpivatianosA,AntoniadesD.Basalcelladenocarcinomaoftheminorsalivarygland:Casereportandcelladhesionmoleculesimmunocytochemicalprofile.OralOncologyEXTRA2005;41(7):150-153

35. AndreadesDA,BelaziM,AntoniadesDZ.Diagnosisofamaxillarybrowntumorassociatedwithhyperparathyroidismsecondarytochronicrenalfailure.Reportofacase.OralHealthPrevDent2004;2:143-147

36. AndreadisDA, Rizos CB, BelaziM, PenevaM, AntoniadesDZ. Encephalocraniocutaneous Lipomatosis accompanied bymaxillary compoundodontomaandjuvenileangiofibroma.Reportofacase.BirthDefectsResearchPartA:ClinicalandMolecularTeratology2004;70(11):889-891

37. BelaziM,VelegrakiA,Koussidou-EremondiT,AndreadisD,HiniS,ArsenisG,EliopoulouC,DestouniE,AntoniadesD.Oralcandidaisolatesinpatientsundergoingradiotherapyforheadandneckcancer.Prevalence,azolesusceptibilityprofileandresponseinantifungaltreatment.Oral


14

MicrobiolImmunol2004;19:347-35138. BelaziM,FlevaA,MarkopoulosA,AndreadisD,DrakoulakosD,DaniilidouN,MichailidouE,KaramitsosD.Serumandsaliva levelsof IL-2 in

childrenwithInsulin–DependentDiabetesMellitus.BalkJStom2004;8:240-242

39. BelaziM,VelegrakiA,Koussidou-EremondiT,AndreadisD,SolonakiF,HiniS,AntoniadesD. Invitrosusceptibilityoforalcandidaspeciestoantifungalagentsinrenaltransplantrecipients.RevClinPharmacolPharmacokinInt2004;18:94-97

Α/Α ABSTRACTSOFINTERNATIONALCONGRESSESPUBLISHEDINJOURNALS

ORRE-PUBLISHEDABSTRACTSCONGRESS

1. AndreadisD,Albanidou-FarmakiE,PoulopoulosA,KatsaresV,ParapanisiouE,MarkopoulosA. Cytokines’ genepolymorphisms inoralmucousmembranepemphigoid.OralDis2014;20(2):9

12th Biennial Congress of the European Association of OralMedicine,Antalya,Turkey11-14/9/2014(Oralpresentation)

2. *AndreadisD,PoulopoulosA,AsimakiA,MarkopoulosA.CondylomaLata:Anunusualoralmanifestationofsyphilis:casereport.OralDis2014;20(2):26

12th Biennial Congress of the European Association of OralMedicine,Antalya,Turkey11-14/9/2014(Posterpresentation)

3. 2.Andreadis D, Poulopoulos A, Malamos D, Epivatianos A. Solitaryangiokeratomaoforalmucosa.OralDis2012;18:s1:1–52

11th Biennial Congress of the European Association of OralMedicine,Athens,Greece15-17/9/2012(Posterpresentation)

4. 3.

MalamosD,AndreadisD.CongenitalagranulocytosisorKostmannsyndrome.CaseReport.OralDis2012;18:s1:1–52

11th Biennial Congress of the European Association of OralMedicine,Athens,Greece15-17/9/2012(Posterpresentation)

5. 4.

KiriliT,SamaraA,PoulopoulosA,AndreadisD,EpivatianosA.Mucocelesandranulasinchildrenandadolescence.Aclinicostatisticalandhistopathologicalstudy.InterJPaediatrDent2011;21(Suppl1):170

InternationalAcademyofPediatricDentistry,Athens,Greece,15-18/6/2011(Posterpresentation)

6. 5

.AndreadisD, PoulopoulosA,Kalekou-GrekaH,PapadopoulosP, EpivatianosA. Localized tongueamyloidosis inapatientwithNeurofibromatosis type II.OralDis2010;16(6):569

10th Biennial Congress of the European Association of OralMedicine,London,UK,23-25/9/2010(Posterpresentation)

7. 6.AndreadisD,PoulopoulosA,NomikosA,EpivatianosA,ChristidisC,BarbatisC, Antoniades D. Altered expression of cell adhesionmolecules E-cadherin,

22nd European Congress of Pathology, Florence, Italy, 4-9/9/2009(Posterpresentation)


15

desmoglein-2, b4-integrin, CD44s (HCAM), and ICAM-1 in acinic cell andsalivaryductaladenocarcinomas.VirchowsArch2009;455(Suppl1):S1-482

8. 7.

AndreadisD,PoulopoulosA,NomikosA,EpivatianosA,ChristidisC,BarbatisC, Antoniades D. Epithelial cell adhesion alterations in salivary glandneoplasms. The paradigm of E-cadherin, desmoglein-2 and b-4 integrin.VirchowsArch2009;455(Suppl1):S1-482

22nd European Congress of Pathology, Florence, Italy, 4-9/9/2009(Posterpresentation)

9. 8.

Epivatianos A, Poulopoulos A, Dimitrakopoulos I,Andreadis D, Nomikos A,Vlachou S, Papazoglou G, Barbatis C. Application of a-smoothmuscle actinand C-KIT in the differential diagnosis of adenoid cystic carcinoma frompolymorphous low-grade adenocarcinoma. Oral Oncology Suppl May2007;2(1):214

1. 1st World Congress of the International Academy ofOralOncology(IAOO),Amsterdam,Netherlands17-20/5/2007(Posterpresentation)

10. 9.

AndreadisD,LaskarisG,MalamosD,AnagnostouD.Plasma-cellMucositisoftheoralcavitypresentedasanirregularulcer:reportofacase.OralDisSupplSeptember2006;12:31

8th Biennial Congress of the European Association of OralMedicine, Zagreb, Croatia 31/8-2/9/2006 (Posterpresentation)

11. 10.

Doukas-Alexiou M, Georgakopoulou E, Gagari E, Andreadis D, Malamos D,KapsokefalosP,LaskarisG.OralPemphigusvulgaris:aclinicostatisticalreviewof157casesinGreece.OralDisSupplSeptember2006;12:5


12. 11.

KapsokefalosP,AndreadisD,Doukas-AlexiouM,GeorgakopoulouE,GagariE,LaskarisG.Mucousmembranepemphigoid:epidemiological findingson149patientswithoralinvolvement.OralDisSupplSeptember2006;12:15


13. 12.

BarbatisC,AndreadisD,EpivatianosA,PoulopoulosA,NomikosA,ChristidisK, Papazoglou G, Antoniades D (abstract). Expression and topographicaldistribution of cell adhesion molecules E-cadherin, beta4-integrin,desmoglein-2, ICAM-1 and HCAM (CD44s) in pleomorphic adenomas ofsalivaryglands.OralOncolSupplApril2005;1(1):135-136

10th InternationalCongress forOralCancer19-24April 2005,Heracklion,Crete,Greece(Oralpresentation)

14. 13.

Poulopoulos A, Andreadis D, Barbatis C, Epivatianos A, Nomikos A,Antoniades D (abstract). Immunohistochemical profile of basal celladenocarcinoma of minor Salivary glands. Oral Oncol Suppl April 2005;1(1):174-175

10th InternationalCongress forOralCancer19-24April 2005,Heracklion,Crete,Greece(Oralpresentation)


16

15. 14.

AndreadisDA,MarkopoulosA:Thepsychologicalprofileofpatientswithoralcancer.(Summary).MundKieferGesichtsChir2001;(5):209-210

MundKieferGesichtsChir2001;(5):209-210

Α/Α PRESENTATIONSININTERNATIONALCONGRESSES(*presenter)

1. AndreadisD,ArvanitidisE,AsimakiA.Gingivalcystofadult.Arareentitywithdiagnosticimportance.8thEuroPerio(EuropeanFederationofPeriodontology,LondonUK3-6/6/2015.(PosterPresentation)

2. AndreadisD,DimitriouA,PatargiaI,AnagnostouE,KolokotronisA.Oralgranularcelltumour(myoblastoma):acasereport).20thCongressofBalkanStomatologicalSociety(Bass),23-26/4/2015,Bucharest,Romania(Oralpresentation)

3. KarampasisA,PoulopoulosA,AndreadisD,PastelliN,BalntoumiE.Oralmanifesttaionsinmyelodysplasticsyndrome.Reportoftheliteratureandreportofthecase.20thCongressofBalkanStomatologicalSociety(Bass),23-26/4/2015,Bucharest,Romania(Posterpresentation)

4. BakopoulouA,KritisA,LeyhausenG,*AndreadisD,PapachristouE,KoidisP,GeurtsenW.AngiogenicpropertiesofSCAPsecretomeundernormoxicandhypoxicconditions.44thIADR,GeneralSession,BostonUSA,11-14/3/2015(Posterpresentation)

5. Andreadis D, Albanidou-Farmaki E, Poulopoulos A, Katsares V, Parapanisiou E, Markopoulos A. Cytokines’ gene polymorphisms in oralmucousmembranepemphigoid.12thBiennialCongressof theEuropeanAssociationofOralMedicine,Antalya,Turkey11-14/9/2014 (Oralpresentation)

6. *AndreadisD,PoulopoulosA,AsimakiA,MarkopoulosA.CondylomaLata:Anunusualoralmanifestationofsyphilis:casereport.12thBiennialCongressoftheEuropeanAssociationofOralMedicine,Antalya,Turkey11-14/9/2014(Posterpresentation)

7. MauroudisS,MesemanoliZ,LetsaS,AndreadisD,PoulopoulosA.Oral lichenplanus.Clinicalcharacteristicsrelatedtomedicalbackgroundandtreatmentresponse.19thCongressofBalkanStomatologicalSociety(Bass),14-17/4/2014,Belgrade,Serbia(oralpresentation)

8. DimitriouA,ParcharidisE,AndreadisD,PoulopoulosA,MarkopoulosA.CD34immunolocalization inminorsalivaryglandsofpatientswith


17

Sjogren’ssyndrome.19thCongressofBalkanStomatologicalSociety(Bass),14-17/4/2014,Belgrade,Serbia(oralpresentation)

9. ChatzisymeonidouS,KontopoulouV,NinikaA,AndreadisD,PoulopoulosA.Orofacialgranulomatosis.Casereportandliteraturereview.19thCongressofBalkanStomatologicalSociety(Bass),14-17/4/2014,Belgrade,Serbia(posterpresentation)

10. Exarchou E, LefkelidouA, Poulopoulos A,AndreadisD, Arapostathis K.Management of a peripheral giant cell granuloma in a child. 19thCongressofBalkanStomatologicalSociety(Bass),14-17/4/2014,Belgrade,Serbia(posterpresentation)

11. *Andreadis D, Albanidou-Farmaki E, Deligiannidis A, Katsares V, Poulopoulos A, Kolokotronis A. TNF-a and IFN-gammapolymorphisms/haplotypes in oral mucous membrane pemphigoid. 46th Meeting of the Continental European Division (CED) of IADR, 4-7/9/2013,Florence,Italy

12. PoulopoulosA,KarakitsosG,HempelM,AndreadisD,MarkopoulosA,GonshorA.AssessmentofHPVinoralleukoplakiautilizingascreeningtest.46thMeetingoftheContinentalEuropeanDivision(CED)ofIADR,4-7/9/2013,Florence,Italy

13. Poulopoulos A, Epivatianos A, Andreadis D, Iordanidis F, Markopoulos A, Antoniadis K. Immunohistochemical profile of primary oralmalignantmelanomas.4οWorldCongressoftheInternationalAcademyofOralOncology(IAOO),RhodesIsland,Greece15-18/5/2013(OralPresentation)

14. KarakoulakiS,TortopidisD,AndreadisD,KoidisP.Evaluationoftherelationshipbetweenbruxismandstress-relatedsalivabiomarker.28thMeetingoftheSocietyofOralPhysiology(StoreKroClub)Amsterdam,TheNetherlands23-26/5/2013.(Posterpresentation)

15. *AndreadisD,Albanidou-FarmakiE,DeligiannidisA,KatsaresV,FarmakisK,PoulopoulosA,MarkopoulosA,ParapanisiouE,EpivatianosA.Cytokines’genepolymorphismsinorallichenplanus.11thBiennialCongressoftheEuropeanAssociationofOralMedicine,Athens,Greece15-17/9/2012(oralposterpresentation)

16. Andreadis D, Poulopoulos A,MalamosD, Epivatianos A. Solitary angiokeratoma of oralmucosa. 11th Biennial Congress of the EuropeanAssociationofOralMedicine,Athens,Greece15-17/9/2012(posterpresentation)

17. Malamos D, Andreadis D. Congenital agranulocytosis or Kostmann syndrome. Case Report. 11th Biennial Congress of the EuropeanAssociationofOralMedicine,Athens,Greece15-17/9/2012,(posterpresentation)

18. *AndreadisD,Albanidou-FarmakiE,DeligiannidisA,KatsaresV,FarmakisK,MarkopoulosA,ParapanisiouE,PoulopoulosA,EpivatianosA.


18

TNF-aandIFN-γgenepolymorphisms/haplotypesinoral lichenplanus.45thMeetingoftheContinentalEuropeanDivision(CED)of IADR,Budapest,Hungary31/8-3/9/2011(posterpresentation).

19. Poulopoulos A, Epivatianos A, Iordanidis F, Andreadis D, Iordanidis S, Markopoulos A. Tenascin-c in chronic submandibular sialadenitisassociatedwithsialolithiasis.45thMeetingof theContinentalEuropeanDivision (CED)of IADR,Budapest,Hungary31/8-3/9/2011 (posterpresentation)

20. Kirili T, SamaraA, PoulopoulosA,AndreadisD, EpivatianosA.Mucoceles and ranulas in childrenandadolescence.A clinicostatistical andhistopathologicalstudy.InternationalAcademyofPediatricDentistry,Athens,Greece,15-18/6/2011(posterpresentation)

21. *Andreadis D, Poulopoulos A, Kalekou-Greka H, Papadopoulos P, Epivatianos A. Localized tongue amyloidosis in a patient withNeurofibromatosis type II. 10th Biennial Congress of the European Association of Oral Medicine, London, UK, 23-25/9/2010 (posterpresentation)

22. *AndreadisD,KyrodimouM,BarbatisC,AmanatiadouE,DrougouA,PoulopoulosA,TsopanomichalouM,Kalekou-GrekaH,EpivatianosA,Vizirianakis I. Differential Desmogleins 2/3 and γ-catenin expression in oral leukoplakia/squamous-cell carcinoma. IADR,General Session,Barcelona,Spain14-17/7/2010(Posterpresentation)

23. *Andreadis D-Markopoulos A-Poulopoulos A-Epivatianos (moderator). Life threatening oral mucosal lesions. 15th Congress of BalkanStomatologicalSociety.Thessaloniki,Greece22-25/4/2010(OralPresentation/Roundtable)

24. NalmpantisD,EliadesA,*AndreadisD,MalamosD,EpivatianosA.Bisphosphonate-inducedosteonecrosisofthejaws.Reportoftwocases.15thCongressofBalkanStomatologicalSociety.Thessaloniki,Greece22-25/4/2010(posterpresentation)

25. Nalmpantis D, Eliades A, Papageorgiou S, Andreadis D, Epivatianos A. Smoking-related oral mucosal lesions. 15th Congress of BalkanStomatologicalSociety.Thessaloniki,Greece22-25/4/2010(posterpresentation)

26. AndreadisD,PoulopoulosA,NomikosA,EpivatianosA,ChristidisC,BarbatisC,AntoniadesD.AlteredexpressionofcelladhesionmoleculesE-cadherin, desmoglein-2, b4-integrin, CD44s(HCAM), and ICAM-1 in acinic cell and salivary ductal adenocarcinomas. 22nd EuropeanCongressofPathology,Florence,Italy,4-9/9/2009(Posterpresentation)

27. AndreadisD,PoulopoulosA,NomikosA,EpivatianosA,ChristidisC,BarbatisC,AntoniadesD.Epithelialcelladhesionalterationsinsalivarygland neoplasms. The paradigm of E-cadherin, desmoglein-2 and b-4 integrin. 22nd European Congress of Pathology, Florence, Italy, 4-


19

9/9/2009(Posterpresentation)

28. *Andreadis D, Rizos C, Belazi M, Peneva M, Antoniades D. Clinical and imaging findings in an encephalocraniocutaneous- lipomatosissyndromecasewithoralmanifestations.9thBiennialCongressoftheEuropeanAssociationofOralMedicine,Salzburg,Austria18-20/9/2008(Posterpresentation)

29. MalamosD,AndreadisD,PsarraK,KapsimaliB,DilimbasisS.Skull involvementinMultipleMyelomapatientswithoralmanifestations.9thBiennialCongressoftheEuropeanAssociationofOralMedicine,Salzburg,Austria18-20/9/2008(Posterpresentation)

30. MalamosD,*AndreadisD,IsaiadisD.OralWartyDyskeratoma.Reportofacase.9thBiennialCongressoftheEuropeanAssociationofOralMedicine,Salzburg,Austria18-20/9/2008(Posterpresentation)

31. AndreadisD,LorenziniG,DrakoulakosD,BelaziM,MichailidouE,VelkosG,Mourellou-TsatsouO,AntoniadesD.PemphigusVulgarisanti-desmoglein-3 and Bullous Pemphigoid anti-BP180 autoantibodies in saliva. 8th European Symposium on Saliva, Egmond aan Zee, TheNetherlands14-17/5/2008(Posterpresentation)

32. *Andreadis D, Christidis K, Papazoglou G, Barbatis C. Immunolocalization of representative cell adhesion molecules in salivary glandcarcinomas. 42nd Annual Meeting of International Association for Dental Research (IADR –CED/ID), Thessaloniki, Greece 26-29/9/2007(Posterpresentation)

33. EpivatianosA, PoulopoulosA,Dimitrakopoulos I,AndreadisD,NomikosA,VlachouS, PapazoglouG,BarbatisC.Applicationof a-smoothmuscleactinandC-KIT inthedifferentialdiagnosisofadenoidcysticcarcinomafrompolymorphous low-gradeadenocarcinoma.1stWorldCongressoftheInternationalAcademyofOralOncology(IAOO),Amsterdam,Netherlands17-20/5/2007(Posterpresentation)

34. *AndreadisD,LaskarisG,MalamosD,AnagnostouD.Plasma-cellmucositisof theoral cavitypresentedasan irregularulcer.Reportofacase.8thBiennialCongressoftheEuropeanAssociationofOralMedicine,Zagreb,Croatia31/8-2/9/2006(Posterpresentation)

35. Doukas-AlexiouM,GeorgakopoulouE,AndreadisD,GagariE,LaskarisG.OralPemphigusvulgaris:aclinicostatisticalreviewof157casesinGreece.8thBiennialCongressoftheEuropeanAssociationofOralMedicine,Zagreb,Croatia31/8-2/9/2006(Oralpresentation)

36. KapsokefalosP,AndreadisD,Doukas-AlexiouM,GeorgakopoulouE,GagariE,LaskarisG.Mucousmembranepemphigoid:epidemiologicalfindingson149patientswithoral involvement.8thBiennialCongressoftheEuropeanAssociationofOralMedicine,Zagreb,Croatia31/8-


20

2/9/2006(Posterpresentation)

37. Andreadis DA, Epivatianos A, Nomikos A, Mireas G, Poulopoulos A, Vlahou E, Antoniades, D, Papazoglou G, Christidis C, Barbatis C.ImmunohistochemicaldetectionofdesmosomalcelladhesionmoleculeDesmoglein-2(Dsg-2)insalivaryglandneoplasms.18thCongressofInternationalFederationofOtorhinolaryngologicalSocieties,25-30June2005,Rome,Italy,(Oralpresentation)

38. BarbatisC,*AndreadisD,EpivatianosA,PoulopoulosA,NomikosA,ChristidisK,PapazoglouG,AntoniadesD.ExpressionandtopographicaldistributionofcelladhesionmoleculesE-cadherin,beta4-integrin,desmoglein-2, ICAM-1andHCAM(CD44s) inpleomorphicadenomasofsalivaryglands.10thInternationalCongressforOralCancer19-24April2005,Heracklion,Crete,Greece(Oralpresentation)

39. Poulopoulos A, Andreadis D, Barbatis C, Epivatianos A, Nomikos A, Antoniades D (abstract). Immunohistochemical profile of basal celladenocarcinomaofminorSalivaryglands.10th InternationalCongress forOralCancer19-24April2005,Heracklion,Crete,Greece (Posterpresentation)

40. VlachouS,AndreadisD,MavroidakosS,NomikosA,AntoniadisD,PapazoglouG,BarbatisC.C-Kitexpressioninsalivaryglandneoplasia:animmunohistochemical study. 5th European Congress of Oto-Rhino-Laryngology, September 14-19, Rhodos-Kos Greece, 2004 (Oralpresentation)

41. ΑntoniadesD*,AndreadisDA,BarbatisC,ChristidisC,EpivatianosA,PoulopoulosA,PapazoglouG.Expressionandtopologicaldistributionofcell adhesionmolecules CD44s, E-cadherin, β4-Integrin, Dsg-2 and ICAM-1 inWarthin tumors of salivary glands. 58thAnnualMeeting&Continuing Education Program of American Academy of Oral and Maxillofacial Pathology, May 8 – 12, S. Carolina, USA, 2004 (Oralpresentation)

42. AntoniadesD*,AndreadisD,ChristidisK,EpivatianosA,PoulopoulosA,PapazoglouG,BarbatisK. Immunohistochemical investigationandstudyof theexpressionandtopographyofcelladhesionmolecules incasesofaciniccelladenocarcinomaofsalivaryglands.58thAnnualMeeting&ContinuingEducationProgramMay8–May12,SouthCarolina,USA,2004

Curriculum Vitae ANDREADIS DIMITRIOS, DDS, PhD, Assistant ... › cv.pdf · 1. Senior Lecturer in...

Documents

Transcript of Curriculum Vitae ANDREADIS DIMITRIOS, DDS, PhD, Assistant ... › cv.pdf · 1. Senior Lecturer in...