Current State of Malaria Vectors in Ecuador and future "niches" of research

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This document was a presentation for a lab meeting at the University of Glasgow (2014) about the current state of malaria vectors in Ecuador and what can be done in the future. Most of the information was gathered from various sources with a special focus on the most recent work done by Dr. Lauren Pinault (2008-2012) in the Ecuadorian Andes.

Transcript of Current State of Malaria Vectors in Ecuador and future "niches" of research

  • Presented by:

    Leonardo Ortega Student at the MSc in QMBCE University of Glasgow 2014

  • starrycluster.wordpress.com

  • www.aitelephone.com www.worldatlas.com

  • www.sangay.com

  • https://www.youtube.com/watch?v=dyPMhd5K7ec

  • Major plasmodium species:

    P. falciparum (14%),

    P. vivax (86%)

    Major anopheles species:

    An.albimanus

    WORLD MALARIA REPORT 2013 commons.wikimedia.org

  • Anopheles (Anopheles) apicimacula Dyar & Knab 1906

    Anopheles (Anopheles) eiseni Coquillett 1902

    Anopheles (Anopheles) gomezdelatorrei Levi-Castillo 1955

    Anopheles (Anopheles) mediopunctatus (Lutz) 1903

    Anopheles (Anopheles) pseudopunctipennis Theobald 1901

    Anopheles (Anopheles) punctimacula Dyar & Knab 1906

    Anopheles (Kerteszia) bambusicolus Komp 1937

    Anopheles (Kerteszia) boliviensis (Theobald) 1905

    Anopheles (Kerteszia) cruzii Dyar & Knab 1908

    Anopheles (Kerteszia) neivai Howard, Dyar & Knab 1912

    Anopheles (Nyssorhynchus) albimanus Wiedemann 1820

    Anopheles (Nyssorhynchus) aquasalis Curry 1932

    Anopheles (Nyssorhynchus) darlingi Root 1926

    Anopheles (Nyssorhynchus) oswaldoi (Peryassu) 1922

    Anopheles (Nyssorhynchus) rangeli Gabaldon, Cova Garcia & Lopez 1940

    Anopheles (Nyssorhynchus) triannulatus (Neiva & Pinto) 1922

    Anopheles (Nyssorhynchus) trinkae Faran 1979

  • Map of all attempted larval collection localities in Ecuador (black circles), between 2008 - 2010. Map prepared in ArcGIS v.9.3 with ESRI World Terrain base

    Pinault and Hunter Malaria Journal 2011, 10:236 http://www.malariajournal.com/content/10/1/236

  • An. albimanus An. pseudopunctipennis

    Circle size (legend) indicates mean number of larvae per dip in a 30-dip sample

  • An. punctimacula An. eiseni

    Circle size (legend) indicates mean number of larvae per dip in a 30-dip sample

  • An. pseudopunctipenis Empty lots (14% of n=30)

    River edges and eddies (28% of n=41)

    An. albimanus Empty lots (14% of n=30)

    River edges and eddies (58% of n=41)

    Road water bodies (26% of n=38)

    An. punctimacula Road water bodies (44% of n=38)

  • An. pseudopunctipenis floating algae

    (cyanobacterial mats),

    warmer temperatures,

    and higher water clarity

    An. Albimanus Permanent habitats,

    sand substrates,

    floating algae (cyanobacterial mats),

    and warmer temperatures

    An. punctimacula floating algae (neg)

    and dissolved oxygen

    An. oswaldoi Not associations

  • SURVEYS: Highland (n=131); Lowland (n=262) Well understanding

    Where disease occurs

    Relationship b/w standing water, mosquitoes and malaria

    Approx. half denied risk at their own properties

    People with potential habitat 50% did not report their presence (definition of suitable

    habitat??)

    Most of at-risk population use bed nets.

  • Consider ecological roles of mosquitoes

    Biochemical research on antimalarials

    Socioeconomical studies for free access

    Transgenesis of mosquitoes

    Transgenesis of Wolbachia

    Ecological studies of mosquitoes

    Link behaviour, adaptation and speciation

    Society empowerment for prevention Educative workshops

    Policies of poverty reduction Access to clean water

    Access to formal education

    Access to formal jobs

    Reduction of social problems (crime, intrafamiliar violence)

    Investment on research