Mayo School of Continuous Professional Development

Coronary Artery DiseasePrevention, Detection & Treatment

Four Seasons Las VegasLas Vegas, Nevada

November 15-17, 2012

Course Directors:Charanjit S. Rihal, M.D., F.A.C.C.Amir Lerman, M.D., F.A.C.C.Robert D. Simari, M.D., F.A.C.C.

General Information

Course DescriptionCoronary Artery Disease: Prevention, Detection & Treatment is designed to provide practicing physicians and healthcare staff with an in-depth overview of the entire spectrum of coronary artery disease. Novel risk factors, state-of-the-art imaging technologies, and new management strategies for patients with acute coronary artery disease will be highlighted. The evolving role of revascularization, interventional cardiology, coronary surgery, and options for the management of advanced non-revascularizable coronary artery disease will be discussed. Population trends and future directions in new scientific breakthroughs such as cell therapy for patients with coronary artery disease will be reviewed.

Course Learning ObjectivesUpon conclusion of this program, participants should be able to:• Distinguishlifestyleinterventionsthatimprovecardiovascularhealthandunderstand

the effects of diabetes, obesity, and metabolic syndrome;• Describethelatestdiagnosticandmanagementstrategiesfortheacutecoronary

syndromes;• Incorporatetheuseofnewerimagingmodalitiesinthedetectionandtreatmentof

complications of myocardial ischemia;• Determinetherisksandbenefitsofscreeningearlydetectionandpreventionin

coronary artery disease; and• Recognizethelatestdiagnosticandmanagementstrategiesforacuteischemicevents

and the latest information on newer platelets and thrombin inhibitors.

Attendance at this Mayo course does not indicate nor guarantee competence or proficiency in the performance of any procedures which may be discussed or taught in this course.

Intended AudienceThe course would be of interest for cardiologists, cardiovascular surgeons, and internists as well as physician assistants and nurse practitioners who see patients with coronary artery disease.

CreditCollege of Medicine, Mayo Clinic, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

College of Medicine, Mayo Clinic, designates this live activity for a maximum of 16 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Other Health Care ProfessionalsA certificate of attendance will be provided to other health care professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations.

Educational GrantsAt the time of this printing, a complete listing of commercial supporters was not available. Appropriate acknowledgment will be given to all supporters at the time of the meeting.

Exhibits will be available for viewing at all scheduled breaks.

Date And LocationCoronary Artery Disease: Prevention, Detection & Treatment will be held November 15 – 17, 2012. The program will be held at the Four Seasons Las Vegas in Las Vegas, Nevada. The program will be held in the Grand Ballroom.

Lodging AccommodationsGuest rooms have been reserved for attendees and their guests with special course rates attheFourSeasonsLasVegasfor$220single/double.Inordertoreceivethespecialrate, reservations must be made before the room block is filled or before the expiration date of October 14, 2012,whichevercomesfirst.Reservationswillbetakenfollowingthis date based on space and rate availability. Please identify yourself as a participant of theMayoClinicCoronaryArteryDiseaseconferencewhenmakingyourreservation.

Lodging arrangements are the sole responsibility of the individual registrant.

Four Seasons Las Vegas – $220 single/double Phone: (702) 632-50003960 Las Vegas Boulevard South Website: http://www.fourseasons.com/Las Vegas, NV lasvegas/

AResortFeeof$20willprovidethefollowingamenities:In-roomwired&wirelesshi-speed internet for multiple devices, wireless high-speed internet access in Four Seasons lobby, pool, and verandah restaurant, full access to fitness center and wet areas, in-room coffee/tea maker, choice of daily newspaper delivered to your room, unlimited localandtoll-freecalls,andshoeshineservice.Inclusionsaresubjecttochangewithoutnotice.

Attending Coronary Artery Disease: Prevention, Detection & Treatment allows participants to experienceeducationandenjoythedynamiclocationofLasVegas.Afterthesession,enjoyworld-classentertainmentandshowsorenjoyoneofthemanyculinarydelightsthe city has to offer.

MayoSchoolofCPDisnotresponsibleforexpensesincurredbyanindividualwhoisnot confirmed and for whom space is not available at the meeting. Costs incurred by the registrant such as airline or hotel fees or penalties are the responsibility of the registrant.

RegistrationREGISTER TODAY! http://www.mayo.edu/cme/cardiovascular-diseases-2012R619

The registration fee includes participant’s tuition, electronic course materials, continental breakfasts, break refreshments, and lunch. Although it is not Mayo School of Continuous ProfessionalDevelopment(CPD)policytolimitthenumberofregistrantsforacourse,conference room facilities may necessitate closing of enrollment; therefore, early registration is advised. A letter of confirmation will be sent upon receipt of payment and completed registration form. Please present the confirmation letter when checking in at the meeting registration desk.

Cancellation PolicyIfyoucancelyourparticipationinthiscourse,yourregistrationfee,lessa$75administrative fee, will be refunded when written notification is received by Mayo SchoolofCPDbeforeNovember1,2012(fax:507-538-0146oremail:cvcme@mayo.edu).No refunds will be made on or after November 1, 2012. Canceled registrations are non-transferable.

MayoSchoolofCPDreservestherighttocancelorpostponeanycourseduetounforeseencircumstances.IntheunlikelyeventMayoSchoolofCPDmustcancelorpostponethiscourse,MayoSchoolofCPDwillrefundtheregistrationfee,butisnotresponsible for any related costs, charges, or expenses to participants, including fees assessed by airline/travel/lodging agencies.

ParkingParking is available at the hotel. The cost for parking is not included in the registration fee.

General Information

FacultyCourse DirectorsCharanjit S. Rihal, M.D., F.A.C.C.Professor of Medicine Chair,DivisionofCardiovascularDiseasesMayoClinic,Rochester,MN

Amir Lerman, M.D., F.A.C.C.Professor of MedicineAssociate Chair for Academic AffairsDirector,ChestPainandCoronaryPhysiology ClinicMayoClinic,Rochester,MN

Robert D. Simari, M.D., F.A.C.C.Professor of MedicineViceChair,DivisionofCardiovascularDiseasesMayoClinic,Rochester,MN

Mayo FacultyThomas G. Allison, Ph.D.Associate Professor of MedicineMayoClinic,Rochester,MN

Naser M. Ammash, M.D.Professor of MedicineMayoClinic,Rochester,MN

Bernard J. Gersh, M.B., Ch.B., D. Phil.Professor of MedicineMayoClinic,Rochester,MN

Rajiv Gulati, M.D., Ph.D.Assistant Professor of MedicineMayoClinic,Rochester,MN

Joerg Herrmann, M.D.Assistant Professor of MedicineMayoClinic,Rochester,MN

Robert (Todd) T. Hurst, M.D.Assistant Professor of MedicineMayo Clinic, Scottsdale, AZ

Kevin Landolfo, M.D.Professor of SurgeryChair, Cardiovascular SurgeryMayo Clinic, Jacksonville, FL

Francisco Lopez-Jimenez, M.D.Professor of MedicineCo-Director,EchocardiographyLaboratoryMayoClinic,Rochester,MN

Issam D. Moussa, M.D.Professor of MedicineChair,DivisionofCardiovascularDiseasesMayo Clinic, Jacksonville, FL

Win-Kuang Shen, M.D.Professor of MedicineChair,DivisionofCardiovascularDiseasesMayo Clinic, Scottsdale, AZ

Eric E. Williamson, M.D.AssistantProfessorofRadiologyMayoClinic,Rochester,MN

R. Scott Wright, M.D.Professor of MedicineMayoClinic,Rochester,MN

Guest FacultyC. Noel Bairey Merz, M.D. Director,Women’sHeartCenterDirector,PreventiveandRehabilitativeCardiac CenterWomen’sGuildEndowedChairinWomen’sHealth,HeartInstituteProfessor of MedicineCedar-Sinai Medical CenterLos Angeles, CA

Kirk N. Garratt, M.D.AssociateDirector,DivisionofCardiacInterventionsClinicalDirector,InterventionalCardiovascularResearchLenoxHillHeartandVascularInstituteNew York, NY

Faculty DisclosureAs a provider accredited by ACCME, College of Medicine, Mayo Clinic (Mayo School of Continuous Professional Development)mustensurebalance,independence,objectivity,andscientificrigor in its educational activities. Course director(s), planning committee, faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercialinterestrelatedtothesubjectmatter of the educational activity. Safeguards against commercial bias have been put in place. Faculty also will disclose any off-label and/or investigational use of pharmaceuticals or instruments discussed in their presentation.Disclosureofthisinformation will be published in course materials so those participants in the activity may formulate their own judgmentsregardingthepresentation.

Faculty

Program Schedule

Thursday, November 15, 2012

7:00 a.m. Registration and Continental Breakfast

7:40 a.m. Welcome, Course Overview, and Outcome Survey

Charanjit S. Rihal, M.D.

Screening and Prevention for CADModerator: Charanjit S. Rihal, M.D.

8:00 a.m. Approaches to Screening for CVD: Who and How Should We Screen

C. Noel Bairey Merz, M.D.

8:30 a.m. Metabolic Syndrome and Heart Disease

Francisco Lopez-Jimenez, M.D.

9:00 a.m. Lipid Management Beyond Statins R. Scott Wright, M.D.

9:30 a.m. Cardiovascular Disease Prevention: Tools in the Home and Office

C. Noel Bairey Merz, M.D.

10:00 a.m. Panel Discussion Drs. Bairey Merz, Lopez-

Jimenez, and Wright

10:15 a.m. Refreshment Break

Detection and Imaging for Coronary Artery DiseaseModerator: Amir Lerman, M.D.

10:35 a.m. Illustrative Case Presentation

Thomas G. Allison, Ph.D.

10:45 a.m. Fractional Flow Reserve (FFR): What Benefit Does

It Offer? Rajiv Gulati, M.D., Ph.D.

11:15 a.m. Imaging for Cardiovascular Risk Prediction. Is There a Role?

Robert (Todd) T. Hurst, M.D.

11:45 a.m. Special Lecture: Eating for a Healthy Heart

Amir Lerman, M.D.

12:05 p.m. Panel Discussion Drs. Allison, Gulati, Hurst,

and Lerman

12:15 p.m. Lunch

Detection and Imaging for Coronary Artery DiseaseModerator: Amir Lerman, M.D.

1:00 p.m. Appropriateness Criteria in Stress Testing and Angiography

Issam D. Moussa, M.D.

1:25 p.m. Cardiopulmonary Exercise Testing in CVD

Thomas G. Allison, Ph.D.

1:50 p.m. Optimal Use of CTA and MR in Ischemic Heart Disease

Eric E. Williamson, M.D.

2:15 p.m. Advances in Intracoronary Imaging Kirk N. Garratt, M.D.

2:40 p.m. Panel Discussion Drs. Moussa, Allison,

Williamson, and Garratt

3:00 p.m. Adjourn

Friday, November 16, 2012

7:15 a.m. Continental Breakfast

Stable Coronary Artery Disease Moderator: Charanjit S. Rihal, M.D.

8:00 a.m. Current State of the Art of CABG Surgery

Kevin Landolfo, M.D.

8:30 a.m. Is There a Role for PCI in Left Main and Multi-Vessel CAD?

Charanjit S. Rihal, M.D.

9:00 a.m. Is Chronic Stable Angina Really Stable: Things May Not Be What They Seem

Bernard J. Gersh, M.B., Ch.B., D. Phil.

9:30 a.m. Panel Discussion Drs. Landolfo, Rihal, and Gersh

10:00 a.m. Refreshment Break10:20 a.m. Chronic Therapy for

Coronary Artery Disease and Stents

Issam D. Moussa, M.D.

10:50 a.m. Rehabilitation in the CAD Patient Francisco Lopez-Jimenez, M.D.

11:20 a.m. How to Manage the Stent Patient Needing Non-Cardiac Surgery

Charanjit S. Rihal, M.D.

11:50 a.m. Panel Discussion Drs. Moussa, Lopez-Jimenez,

and Rihal

12:00 p.m. Lunch

Acute Coronary Artery Disease Moderator: Robert D. Simari, M.D. KEYNOTE ADDRESS:1:00 p.m. Indications for

Revascularization in Patients with Chronic Stable Angina: Reconciling the Randomized Trials

Bernard J. Gersh, M.B., Ch.B., D. Phil.

1:30 p.m. Biomarkers for Acute Coronary Syndrome

Joerg Herrmann, M.D.

2:00 p.m. Spontaneous Coronary Artery Dissection

Rajiv Gulati, M.D., Ph.D.

2:30 p.m. Cell Therapy for Acute MI Robert D. Simari, M.D.

3:00 p.m. Adjourn

Saturday, November 17, 2012

7:15 a.m. Continental Breakfast

7:45 a.m. Course Summary and Post-Test Charanjit S. Rihal, M.D.

Treatment: Special TopicsModerator: Robert D. Simari, M.D.

8:00 a.m. Renal Sympathetic Ablation for Resistant Hypertension

Rajiv Gulati, M.D., Ph.D.

8:25 a.m. The Epidemic of Congenital Coronary Anomalies

Naser M. Ammash, M.D.

8:50 a.m. Endothelial Function in Clinical Practice

Amir Lerman, M.D.

9:25 a.m. Management of the Non-Revascularized Patient

Robert D. Simari, M.D.

9:50 a.m. Panel Discussion Drs. Gulati, Ammash, and

Lerman

10:00 a.m. Refreshment Break

Moderator: Charanjit S. Rihal, M.D.

10:15 a.m. Theinopyridine - Proton Pump Inhibitor Interactions: In Vitro or

In Vivo? Charanjit S. Rihal, M.D.

10:40 a.m. Ischemic Heart Disease and Atrial Fibrillation

Win-Kuang Shen, M.D.

11:05 a.m. The Challenge of Treating the Patient With Heart Disease and Cancer

Joerg Herrmann, M.D.

11:30 a.m. Ischemic Cardiomyopathy Win-Kuang Shen, M.D.

11:55 a.m. Panel Discussion Drs. Herrmann and Shen

12:15 p.m. Closing Comments & Adjourn

Program Schedule

REGISTRATIONRegister online:

http://www.mayo.edu/cme/cardiovascular-diseases-2012R619

Registration Fee:Course Registration (Physicians and Scientists) $750.00 Course Registration (Resident) $600.00

MayoClinicDivisionofCardiologyhasrecentlyimplementedanonlineconferenceregistrationsystem.Ifthisisyourfirsttimeusingtheonlinesystem,you will need to create a profile and login account.

Registerbyenteringtheurl:http://www.mayo.edu/cme/cardiovascular-diseases-2012R619 and click on Register Now. The system will step you through the profile and login process. An email address is required upon registration. A letter of confirmation will be forwarded to this address upon receipt of payment and submitted registration. Present this letter of confirmation when checking in at the meeting registration desk. The registration fee includes tuition, electronic course syllabus, continental breakfasts, break refreshments, and lunch.

AlthoughitisnotMayoSchoolofContinuousProfessionalDevelopment(CPD)policy to limit the number of registrants for a course, conference room facilities may necessitate closing of enrollment; therefore, early registration is advised. Enrollment for this program is limited. A letter of confirmation will be e-mailed upon receipt of payment. Please present the confirmation letter when checking in at the meeting registration desk.

For additional information, contact:Cardiovascular Continuing Education200FirstStreetSW-Gonda6Rochester,MN55905

E-mail: cvcme@mayo.eduPhone: 800-283-6296or507-266-0677Website: www.mayo.edu/cme/cardiovascular-diseases

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