Copyright © John Wiley & Sons, Inc. All rights reserved. When DNA is transcribed, the result is an...

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Copyright © John Wiley & Sons, Inc. All rights reserved. When DNA is transcribed, the result is an RNA molecule. RNA is then translated into a sequence of amino acids in a polypeptide.

Transcript of Copyright © John Wiley & Sons, Inc. All rights reserved. When DNA is transcribed, the result is an...

Page 1: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

When DNA is transcribed, the result is an RNA molecule.

RNA is then translated into a sequence of amino acids in a polypeptide.

Page 2: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Triplets of bases

• Specify all the amino acids.

• Are called codons.

Page 3: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Transcription: From DNA to RNA In transcription,

• Genetic information is transferred from DNA to RNA.

• An RNA molecule is transcribed from a DNA template.

Transcription

Page 4: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Initiation of Transcription The “start transcribing”

signal is a nucleotide

sequence called a

promoter.

The first phase of

transcription is initiation:

• RNA polymerase

attaches to the promoter.

• RNA synthesis begins.

Page 5: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

RNA Elongation The second phase of

transcription is elongation:

• The RNA grows longer.

Page 6: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Termination of Transcription The third phase of

transcription is

termination:

• RNA polymerase

reaches a sequence

of DNA bases

called a terminator.

Page 7: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

The Processing of Eukaryotic RNA The eukaryotic cell processes the RNA after transcription.

Page 8: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Translation: The Players Translation

• Is the conversion from the nucleic acid language to the

protein language.

Page 9: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Messenger RNA (mRNA) mRNA

• Is the first ingredient for

translation.

Page 10: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Transfer RNA (tRNA) tRNA

• Acts as a molecular

interpreter.

• Carries amino

acids.

• Matches amino

acids with codons

in mRNA using

anticodons.

Page 11: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Ribosomes Ribosomes

• Are organelles that actually

make polypeptides.

• Are made up of two

protein subunits.

• Contain ribosomal RNA

(rRNA).

Page 12: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Translation

Page 13: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Translation

Page 14: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Translation

Page 15: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Translation

Page 16: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Translation

Page 17: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Translation

Page 18: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Translation

Page 19: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Translation

Page 20: Copyright © John Wiley & Sons, Inc. All rights reserved.  When DNA is transcribed, the result is an RNA molecule.  RNA is then translated into a sequence.

Copyright © John Wiley & Sons, Inc. All rights reserved.

Review: DNA RNA Protein The flow of genetic information in a cell