Commentary: Memory for spatial locations, motor responses, and objects: triple dissociation among...
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![Page 1: Commentary: Memory for spatial locations, motor responses, and objects: triple dissociation among the hippocampus, caudate nucleus, and extrastriate visual.](https://reader036.fdocuments.us/reader036/viewer/2022081503/5a4d1b4d7f8b9ab0599a65ae/html5/thumbnails/1.jpg)
Commentary:Commentary:Memory for spatial locations, motor responses, and Memory for spatial locations, motor responses, and objects: triple dissociation among the hippocampus, objects: triple dissociation among the hippocampus,
caudate nucleus, and extrastriate visual cortexcaudate nucleus, and extrastriate visual cortex(Raymond P. Kesner, Bridget L. Bolland, Manoli Dakis, (Raymond P. Kesner, Bridget L. Bolland, Manoli Dakis,
1992)1992)
Courtney DawsonSamantha FabbriNish PaisCristian RochaAvik Sarkar
![Page 2: Commentary: Memory for spatial locations, motor responses, and objects: triple dissociation among the hippocampus, caudate nucleus, and extrastriate visual.](https://reader036.fdocuments.us/reader036/viewer/2022081503/5a4d1b4d7f8b9ab0599a65ae/html5/thumbnails/2.jpg)
BackgroundIntroduction
Contradictory Evidence Recent StudiesFollow-up Study
Conclusion
1. Background2. Introduction3. Contradictory Evidence4. Recent Studies5. Follow-up Study6. Conclusions
Schedule
![Page 3: Commentary: Memory for spatial locations, motor responses, and objects: triple dissociation among the hippocampus, caudate nucleus, and extrastriate visual.](https://reader036.fdocuments.us/reader036/viewer/2022081503/5a4d1b4d7f8b9ab0599a65ae/html5/thumbnails/3.jpg)
BackgroundIntroduction
Contradictory Evidence Recent Studies
Follow-up Study ConclusionBackground
Hippocampus
Spatial Location Response Visual
Object Info
1. Hippocampus exclusively mediates all incoming informationINPUT
Samantha Fabbri
![Page 4: Commentary: Memory for spatial locations, motor responses, and objects: triple dissociation among the hippocampus, caudate nucleus, and extrastriate visual.](https://reader036.fdocuments.us/reader036/viewer/2022081503/5a4d1b4d7f8b9ab0599a65ae/html5/thumbnails/4.jpg)
BackgroundIntroduction
Contradictory Evidence Recent Studies
Follow-Up StudyConclusion
HippocampusCaudate Nucleus
Extra-striate Visual Cortex
INPUT
Spatial LocationResponse
Visual Object Info
2. Triple dissociation among the hippocampus, caudate nucleus and extra-striate visual cortex
Samantha Fabbri
![Page 5: Commentary: Memory for spatial locations, motor responses, and objects: triple dissociation among the hippocampus, caudate nucleus, and extrastriate visual.](https://reader036.fdocuments.us/reader036/viewer/2022081503/5a4d1b4d7f8b9ab0599a65ae/html5/thumbnails/5.jpg)
BackgroundIntroduction
Contradictory Evidence Recent Studies
Follow-up Study Conclusion
triple dissociation among: hippocampus caudate nucleus extra-striate visual cortex
Response Spatial location Visual object recognition
Introduction
Samantha Fabbri
![Page 6: Commentary: Memory for spatial locations, motor responses, and objects: triple dissociation among the hippocampus, caudate nucleus, and extrastriate visual.](https://reader036.fdocuments.us/reader036/viewer/2022081503/5a4d1b4d7f8b9ab0599a65ae/html5/thumbnails/6.jpg)
BackgroundIntroduction
Contradictory Evidence Recent Studies
Follow-up Study Conclusion
Spatial location controls received cortical lesions
Response and visual object controls received sham-operated control Lesions
The extent of each lesion was variable
Lesions ?
Courtney Dawson
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Olfactory Cues One study regarding odor familiarity in a radial maze hypothesized
that such patterns of exploration would depend upon the olfactory environment
olfactory information can act as directional cues for animals exploring the radial maze.
BackgroundIntroduction
Contradictory Evidence Recent Studies
Follow-up Study Conclusion
Avik Sarkar
![Page 8: Commentary: Memory for spatial locations, motor responses, and objects: triple dissociation among the hippocampus, caudate nucleus, and extrastriate visual.](https://reader036.fdocuments.us/reader036/viewer/2022081503/5a4d1b4d7f8b9ab0599a65ae/html5/thumbnails/8.jpg)
BackgroundIntroduction
Contradictory Evidence Recent Studies
Follow-Up StudyConclusionRecent Studies
Voermans et al. 2004. Interaction between the Human Hippocampus and the Caudate Nucleus during Route Recognition. Neuron. 43:427-435.
Courtney Dawson
![Page 9: Commentary: Memory for spatial locations, motor responses, and objects: triple dissociation among the hippocampus, caudate nucleus, and extrastriate visual.](https://reader036.fdocuments.us/reader036/viewer/2022081503/5a4d1b4d7f8b9ab0599a65ae/html5/thumbnails/9.jpg)
Mizumori, S., Yeshenko, O., Gill, K., and Davis, D. 2004. Parallel processing across neural systems: Implications for a multiple memory system hypothesis. Neuro. Learning and Memory. 82:278-298.
BackgroundIntroduction
Contradictory Evidence Recent Studies
Follow-Up StudyConclusion
Avik Sarkar
![Page 10: Commentary: Memory for spatial locations, motor responses, and objects: triple dissociation among the hippocampus, caudate nucleus, and extrastriate visual.](https://reader036.fdocuments.us/reader036/viewer/2022081503/5a4d1b4d7f8b9ab0599a65ae/html5/thumbnails/10.jpg)
BackgroundIntroduction
Contradictory Evidence Recent Studies
Follow-Up StudyConclusionFollow-Up StudyFollow-Up Study
Purpose Is there an interaction between the hippocampus, caudate nucleus and extra-striate visual cortex in mediating working memory?
Method Selectively lesion either: 1. The hippocampus and caudate nucleus 2. The hippocampus and extra-striate visual cortex 3. Extra-striate visual cortex and caudate nucleus 4. Only the hippocampus
Courtney Dawson
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BackgroundIntroduction
Contradictory Evidence Recent Studies
Follow-Up StudyConclusionConclusionConclusion
Our Revised Conclusion Multiple-memory systems exist and converge at a
higher processing level.
Avik Sarkar
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IntroductionBackground
Methods / Results Supporting Evidence
Contradictory Evidence Further Research
Conclusion
Birke, L., Sadler, D., 1999. Effects of odor familiarity on the development of systematic exploration in the spiny mouse, Acomys cahirinus. Developmental psychobiology. 20(6):627-40
Cohen, Y., Reuveni, I., Barkai, E., Maroun, M. 2008. Olfactory learning-induced long-lasting enhancement of descending and ascending synaptic transmission to the piriform cortex. Journal of Neuroscience. 28(26):6664-9.
Kesner, P. Bolland, B. and Dakis, M. 1992. Memory for spatial locations, Motor responses and objects: triple dissociation among the hippocampus, caudate nucleus, and extrastriate visual cortex. Exp. Brain Res. 93:462-470.
Mizumori, S., Yeshenko, O., Gill, K., and Davis, D. 2004. Parallel processing across neural systems: Implications for a multiple memory system hypothesis. Neuro. Learning and Memory. 82:278-298.
Voermans et al. 2004. Interaction between the Human Hippocampus and the Caudate Nucleus during Route Recognition. Neuron. 43:427-435.
ReferencesReferences
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BackgroundIntroduction
Contradictory Evidence Recent Studies
Follow-Up StudyConclusionThe End The End