Chapter 12 – DNA and Proteins DNA Structure: DNA is made of many smaller subunits called...
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Transcript of Chapter 12 – DNA and Proteins DNA Structure: DNA is made of many smaller subunits called...
Chapter 12 ndash DNA and ProteinsDNA Structure
DNA is made of many smaller subunitscalled nucleotides
A nucleotide has 3 parts
1A sugar (a 5 Carbon deoxyribose)2A Phosphate group3A nitrogenous base - 4 types of these
Adenine (A) Thymine (T)Cytosine (C)Guanine (G)
Always pair up
Always pair up
Adenine and Guanine are purines (bigger)Cytosine and Thymine are pyrimidines (smaller)
These subunits are arranged in a twisted ladder called a double helix
If you untwisted the ladder it would look like this nitrogen base
phosphate
Sugar
weak hydrogen bonds hold the bases together
The sequence (or order) of the bases in allorganismsrsquo DNA is what makes them different from each other
A gene is a segment of DNA that codes for a specific trait
Stop for DNA structure activity
Be careful with thesehellipthey are borrowed from Mr Pontzer Please return them exactly as you found them Thank you
Build a double helix using the drawing you made in your notes Look at the example up front to see how it goes together
Key is on the next page
Tubes Other piecesRed = Adenine Sugar = blackBlue = Thymine Phosphate = redGreen = GuanineGray = Cytosine
White round pieces are Yellow tubes are the hydogen bonds the phosphatesugar bonds bonds(correct bases must pair)
Longest and longer green tubes are to make a stand for the DNA molecule
Protein Synthesis
Remember - Proteins have specificshapes for specific functions
- Proteins are made from long
chains of 20 types of amino acids
DNA tells our cells how to put proteins together
- Different proteins exist because amino acids are assembled in different sequences
Steps of protein synthesis1Transcription ndash In the nucleus the DNA code is ldquocopiedrdquo onto a molecule of messenger RNA (mRNA) by matching up base pairs RNA contains uracil (U) instead of thymine(T)
After transcription the mRNA leaves thenucleus and moves to the ribosome
2 Translation ndash The ribosome reads the mRNA in 3-base sequences called codons
Specific amino acids are added to a growing protein chain They are matchedup with an anticodon found on a transfer RNA (tRNA) molecule
What is a mutation1048708 Any change in DNA1048708 Any abnormal change in genetic
materialSome can be inherited by the nextgeneration if they are present in sex cells
What causes a mutation
1) Changes in the environment ORmutagens
a ultraviolet radiationb pollutants and chemicalsc tar from tobacco
2) Errors during replication transcriptionor translation
Types of mutations
1048708 Point mutationssmall (but significant) changes often ina single nucleotide base
Example Sickle Cell Anemia is caused by a point mutation
1048708
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
A nucleotide has 3 parts
1A sugar (a 5 Carbon deoxyribose)2A Phosphate group3A nitrogenous base - 4 types of these
Adenine (A) Thymine (T)Cytosine (C)Guanine (G)
Always pair up
Always pair up
Adenine and Guanine are purines (bigger)Cytosine and Thymine are pyrimidines (smaller)
These subunits are arranged in a twisted ladder called a double helix
If you untwisted the ladder it would look like this nitrogen base
phosphate
Sugar
weak hydrogen bonds hold the bases together
The sequence (or order) of the bases in allorganismsrsquo DNA is what makes them different from each other
A gene is a segment of DNA that codes for a specific trait
Stop for DNA structure activity
Be careful with thesehellipthey are borrowed from Mr Pontzer Please return them exactly as you found them Thank you
Build a double helix using the drawing you made in your notes Look at the example up front to see how it goes together
Key is on the next page
Tubes Other piecesRed = Adenine Sugar = blackBlue = Thymine Phosphate = redGreen = GuanineGray = Cytosine
White round pieces are Yellow tubes are the hydogen bonds the phosphatesugar bonds bonds(correct bases must pair)
Longest and longer green tubes are to make a stand for the DNA molecule
Protein Synthesis
Remember - Proteins have specificshapes for specific functions
- Proteins are made from long
chains of 20 types of amino acids
DNA tells our cells how to put proteins together
- Different proteins exist because amino acids are assembled in different sequences
Steps of protein synthesis1Transcription ndash In the nucleus the DNA code is ldquocopiedrdquo onto a molecule of messenger RNA (mRNA) by matching up base pairs RNA contains uracil (U) instead of thymine(T)
After transcription the mRNA leaves thenucleus and moves to the ribosome
2 Translation ndash The ribosome reads the mRNA in 3-base sequences called codons
Specific amino acids are added to a growing protein chain They are matchedup with an anticodon found on a transfer RNA (tRNA) molecule
What is a mutation1048708 Any change in DNA1048708 Any abnormal change in genetic
materialSome can be inherited by the nextgeneration if they are present in sex cells
What causes a mutation
1) Changes in the environment ORmutagens
a ultraviolet radiationb pollutants and chemicalsc tar from tobacco
2) Errors during replication transcriptionor translation
Types of mutations
1048708 Point mutationssmall (but significant) changes often ina single nucleotide base
Example Sickle Cell Anemia is caused by a point mutation
1048708
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
These subunits are arranged in a twisted ladder called a double helix
If you untwisted the ladder it would look like this nitrogen base
phosphate
Sugar
weak hydrogen bonds hold the bases together
The sequence (or order) of the bases in allorganismsrsquo DNA is what makes them different from each other
A gene is a segment of DNA that codes for a specific trait
Stop for DNA structure activity
Be careful with thesehellipthey are borrowed from Mr Pontzer Please return them exactly as you found them Thank you
Build a double helix using the drawing you made in your notes Look at the example up front to see how it goes together
Key is on the next page
Tubes Other piecesRed = Adenine Sugar = blackBlue = Thymine Phosphate = redGreen = GuanineGray = Cytosine
White round pieces are Yellow tubes are the hydogen bonds the phosphatesugar bonds bonds(correct bases must pair)
Longest and longer green tubes are to make a stand for the DNA molecule
Protein Synthesis
Remember - Proteins have specificshapes for specific functions
- Proteins are made from long
chains of 20 types of amino acids
DNA tells our cells how to put proteins together
- Different proteins exist because amino acids are assembled in different sequences
Steps of protein synthesis1Transcription ndash In the nucleus the DNA code is ldquocopiedrdquo onto a molecule of messenger RNA (mRNA) by matching up base pairs RNA contains uracil (U) instead of thymine(T)
After transcription the mRNA leaves thenucleus and moves to the ribosome
2 Translation ndash The ribosome reads the mRNA in 3-base sequences called codons
Specific amino acids are added to a growing protein chain They are matchedup with an anticodon found on a transfer RNA (tRNA) molecule
What is a mutation1048708 Any change in DNA1048708 Any abnormal change in genetic
materialSome can be inherited by the nextgeneration if they are present in sex cells
What causes a mutation
1) Changes in the environment ORmutagens
a ultraviolet radiationb pollutants and chemicalsc tar from tobacco
2) Errors during replication transcriptionor translation
Types of mutations
1048708 Point mutationssmall (but significant) changes often ina single nucleotide base
Example Sickle Cell Anemia is caused by a point mutation
1048708
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
The sequence (or order) of the bases in allorganismsrsquo DNA is what makes them different from each other
A gene is a segment of DNA that codes for a specific trait
Stop for DNA structure activity
Be careful with thesehellipthey are borrowed from Mr Pontzer Please return them exactly as you found them Thank you
Build a double helix using the drawing you made in your notes Look at the example up front to see how it goes together
Key is on the next page
Tubes Other piecesRed = Adenine Sugar = blackBlue = Thymine Phosphate = redGreen = GuanineGray = Cytosine
White round pieces are Yellow tubes are the hydogen bonds the phosphatesugar bonds bonds(correct bases must pair)
Longest and longer green tubes are to make a stand for the DNA molecule
Protein Synthesis
Remember - Proteins have specificshapes for specific functions
- Proteins are made from long
chains of 20 types of amino acids
DNA tells our cells how to put proteins together
- Different proteins exist because amino acids are assembled in different sequences
Steps of protein synthesis1Transcription ndash In the nucleus the DNA code is ldquocopiedrdquo onto a molecule of messenger RNA (mRNA) by matching up base pairs RNA contains uracil (U) instead of thymine(T)
After transcription the mRNA leaves thenucleus and moves to the ribosome
2 Translation ndash The ribosome reads the mRNA in 3-base sequences called codons
Specific amino acids are added to a growing protein chain They are matchedup with an anticodon found on a transfer RNA (tRNA) molecule
What is a mutation1048708 Any change in DNA1048708 Any abnormal change in genetic
materialSome can be inherited by the nextgeneration if they are present in sex cells
What causes a mutation
1) Changes in the environment ORmutagens
a ultraviolet radiationb pollutants and chemicalsc tar from tobacco
2) Errors during replication transcriptionor translation
Types of mutations
1048708 Point mutationssmall (but significant) changes often ina single nucleotide base
Example Sickle Cell Anemia is caused by a point mutation
1048708
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
Stop for DNA structure activity
Be careful with thesehellipthey are borrowed from Mr Pontzer Please return them exactly as you found them Thank you
Build a double helix using the drawing you made in your notes Look at the example up front to see how it goes together
Key is on the next page
Tubes Other piecesRed = Adenine Sugar = blackBlue = Thymine Phosphate = redGreen = GuanineGray = Cytosine
White round pieces are Yellow tubes are the hydogen bonds the phosphatesugar bonds bonds(correct bases must pair)
Longest and longer green tubes are to make a stand for the DNA molecule
Protein Synthesis
Remember - Proteins have specificshapes for specific functions
- Proteins are made from long
chains of 20 types of amino acids
DNA tells our cells how to put proteins together
- Different proteins exist because amino acids are assembled in different sequences
Steps of protein synthesis1Transcription ndash In the nucleus the DNA code is ldquocopiedrdquo onto a molecule of messenger RNA (mRNA) by matching up base pairs RNA contains uracil (U) instead of thymine(T)
After transcription the mRNA leaves thenucleus and moves to the ribosome
2 Translation ndash The ribosome reads the mRNA in 3-base sequences called codons
Specific amino acids are added to a growing protein chain They are matchedup with an anticodon found on a transfer RNA (tRNA) molecule
What is a mutation1048708 Any change in DNA1048708 Any abnormal change in genetic
materialSome can be inherited by the nextgeneration if they are present in sex cells
What causes a mutation
1) Changes in the environment ORmutagens
a ultraviolet radiationb pollutants and chemicalsc tar from tobacco
2) Errors during replication transcriptionor translation
Types of mutations
1048708 Point mutationssmall (but significant) changes often ina single nucleotide base
Example Sickle Cell Anemia is caused by a point mutation
1048708
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
Tubes Other piecesRed = Adenine Sugar = blackBlue = Thymine Phosphate = redGreen = GuanineGray = Cytosine
White round pieces are Yellow tubes are the hydogen bonds the phosphatesugar bonds bonds(correct bases must pair)
Longest and longer green tubes are to make a stand for the DNA molecule
Protein Synthesis
Remember - Proteins have specificshapes for specific functions
- Proteins are made from long
chains of 20 types of amino acids
DNA tells our cells how to put proteins together
- Different proteins exist because amino acids are assembled in different sequences
Steps of protein synthesis1Transcription ndash In the nucleus the DNA code is ldquocopiedrdquo onto a molecule of messenger RNA (mRNA) by matching up base pairs RNA contains uracil (U) instead of thymine(T)
After transcription the mRNA leaves thenucleus and moves to the ribosome
2 Translation ndash The ribosome reads the mRNA in 3-base sequences called codons
Specific amino acids are added to a growing protein chain They are matchedup with an anticodon found on a transfer RNA (tRNA) molecule
What is a mutation1048708 Any change in DNA1048708 Any abnormal change in genetic
materialSome can be inherited by the nextgeneration if they are present in sex cells
What causes a mutation
1) Changes in the environment ORmutagens
a ultraviolet radiationb pollutants and chemicalsc tar from tobacco
2) Errors during replication transcriptionor translation
Types of mutations
1048708 Point mutationssmall (but significant) changes often ina single nucleotide base
Example Sickle Cell Anemia is caused by a point mutation
1048708
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
Protein Synthesis
Remember - Proteins have specificshapes for specific functions
- Proteins are made from long
chains of 20 types of amino acids
DNA tells our cells how to put proteins together
- Different proteins exist because amino acids are assembled in different sequences
Steps of protein synthesis1Transcription ndash In the nucleus the DNA code is ldquocopiedrdquo onto a molecule of messenger RNA (mRNA) by matching up base pairs RNA contains uracil (U) instead of thymine(T)
After transcription the mRNA leaves thenucleus and moves to the ribosome
2 Translation ndash The ribosome reads the mRNA in 3-base sequences called codons
Specific amino acids are added to a growing protein chain They are matchedup with an anticodon found on a transfer RNA (tRNA) molecule
What is a mutation1048708 Any change in DNA1048708 Any abnormal change in genetic
materialSome can be inherited by the nextgeneration if they are present in sex cells
What causes a mutation
1) Changes in the environment ORmutagens
a ultraviolet radiationb pollutants and chemicalsc tar from tobacco
2) Errors during replication transcriptionor translation
Types of mutations
1048708 Point mutationssmall (but significant) changes often ina single nucleotide base
Example Sickle Cell Anemia is caused by a point mutation
1048708
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
Steps of protein synthesis1Transcription ndash In the nucleus the DNA code is ldquocopiedrdquo onto a molecule of messenger RNA (mRNA) by matching up base pairs RNA contains uracil (U) instead of thymine(T)
After transcription the mRNA leaves thenucleus and moves to the ribosome
2 Translation ndash The ribosome reads the mRNA in 3-base sequences called codons
Specific amino acids are added to a growing protein chain They are matchedup with an anticodon found on a transfer RNA (tRNA) molecule
What is a mutation1048708 Any change in DNA1048708 Any abnormal change in genetic
materialSome can be inherited by the nextgeneration if they are present in sex cells
What causes a mutation
1) Changes in the environment ORmutagens
a ultraviolet radiationb pollutants and chemicalsc tar from tobacco
2) Errors during replication transcriptionor translation
Types of mutations
1048708 Point mutationssmall (but significant) changes often ina single nucleotide base
Example Sickle Cell Anemia is caused by a point mutation
1048708
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
2 Translation ndash The ribosome reads the mRNA in 3-base sequences called codons
Specific amino acids are added to a growing protein chain They are matchedup with an anticodon found on a transfer RNA (tRNA) molecule
What is a mutation1048708 Any change in DNA1048708 Any abnormal change in genetic
materialSome can be inherited by the nextgeneration if they are present in sex cells
What causes a mutation
1) Changes in the environment ORmutagens
a ultraviolet radiationb pollutants and chemicalsc tar from tobacco
2) Errors during replication transcriptionor translation
Types of mutations
1048708 Point mutationssmall (but significant) changes often ina single nucleotide base
Example Sickle Cell Anemia is caused by a point mutation
1048708
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
What is a mutation1048708 Any change in DNA1048708 Any abnormal change in genetic
materialSome can be inherited by the nextgeneration if they are present in sex cells
What causes a mutation
1) Changes in the environment ORmutagens
a ultraviolet radiationb pollutants and chemicalsc tar from tobacco
2) Errors during replication transcriptionor translation
Types of mutations
1048708 Point mutationssmall (but significant) changes often ina single nucleotide base
Example Sickle Cell Anemia is caused by a point mutation
1048708
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
What causes a mutation
1) Changes in the environment ORmutagens
a ultraviolet radiationb pollutants and chemicalsc tar from tobacco
2) Errors during replication transcriptionor translation
Types of mutations
1048708 Point mutationssmall (but significant) changes often ina single nucleotide base
Example Sickle Cell Anemia is caused by a point mutation
1048708
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
Types of mutations
1048708 Point mutationssmall (but significant) changes often ina single nucleotide base
Example Sickle Cell Anemia is caused by a point mutation
1048708
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
Point Mutation
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
Types of mutations
1048708Frame Shift when either insertion or deletion of one or two nucleotide bases When this occurs the ldquoreading framerdquo is changed so that all the codons read after the mutation are incorrect
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
Disorders that result from mutations
1048708 Sickle Cell Anemia1048708 PKU1048708 Cystic Fibrosis
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-
End Result
Different polypeptide or protein chainscan be made from differentamino acid sequences These proteinswill have different functions
Chromosomal Mutations
- Slide 1
- Slide 2
- Slide 3
- Slide 4
- Slide 5
- Slide 6
- Slide 7
- Slide 8
- Slide 9
- Slide 10
- Slide 11
- Slide 12
- Slide 13
- Slide 14
- Slide 15
- Slide 16
- Slide 17
- Slide 18
- Slide 19
-