Cancer survival in the UK and Republic of Ireland

B Rachet1, M Quinn2, D Brewster3, A Gavin4, J Steward5,

H Comber6, L Gonsalves7, V Mak8, MP Coleman1

1 London School of Hygiene and Tropical Medicine2 Office for National Statistics3 Scottish Cancer Registry 4 Northern Ireland Cancer Registry

5 Welsh Cancer Intelligence Unit6 Republic of Ireland Cancer Registry7 West Midlands Cancer Intelligence Unit 8 Thames Cancer Registry

CR UK funding

OBJECTIVE

Estimate 1- and 5-year survival up to 2001

•20 most common cancers

•England, Scotland, Wales, Northern Ireland, Republic of Ireland

•Cohort/complete and period approaches

MATERIAL

All registered adult cancers

Diagnostic periodEngland, Scotland, Wales 1991-99Northern Ireland 1993-99Republic of Ireland 1994-99

Follow-up: 31 December 2001

190,998

1,531,819

40,365

69,309

106,170

RELATIVE SURVIVAL

•Maximum likelihood approach

•Sex, period of diagnosis (1991-95, 1996-99), country

•National life tables

- centred on 1991 for 1991-95 deaths

- centred on 1996 for 1996-2001 deaths

•Regional life tables for GOR analysis

•Unstandardised vs. age-standardised analyses

•Period analysis for short-term prediction

Breast cancer, women, UK and Republic of Ireland, 1991-99

Zero survival (%)

Multiples (%)

Included

N. Ireland 1.5 0.9 5,866

R. of Ireland 1.7 1.0 9,590

Wales 6.0 1.5 16,475

Scotland 2.2 6.2 27,057

England 5.6 2.5 250,299

      309,287

UK and R IRELANDSCOTLAND

WALESN IRELANDR IRELANDENGLANDNorth East

North WestYorkshire Hum.

East MidlandsWest Midlands

EastLondon

South EastSouth West

0 20 40 60 80 1005-year relative survival (%)

Part 2 Analysis: Non-standardised

Cases diagnosed 1991-95

BREAST (Females)BREAST

Women diagnosed 1991-95

UK and R IRELANDSCOTLAND

WALESN IRELANDR IRELANDENGLANDNorth East

North WestYorkshire Hum.

East MidlandsWest Midlands

EastLondon

South EastSouth West

0 20 40 60 80 1005-year relative survival (%)

Part 2 Analysis: Non-standardised

Cases diagnosed 1991-95

BREAST (Females)

UK and R IRELANDSCOTLAND

WALESN IRELANDR IRELANDENGLANDNorth East

North WestYorkshire Hum.

East MidlandsWest Midlands

EastLondon

South EastSouth West

0 20 40 60 80 1005-year relative survival (%)

Part 2 Analysis: Non-standardised

Cases diagnosed 1996-99

BREAST (Females)Breast, women diagnosed 1996-99

Breast, women diagnosed 1991-95

Colon cancer, men, UK and Republic of Ireland, 1991-99

Zero survival (%)

Multiples (%)

Included

N. Ireland 4.3 2.5 1,964

R. of Ireland 4.7 2.9 3,336

Wales 12.7 2.0 4,675

Scotland 3.7 7.8 8,321

England 10.6 3.6 64,409

      82,705

UK and R IRELANDSCOTLAND

WALESN IRELANDR IRELANDENGLANDNorth East

North WestYorkshire Hum.

East MidlandsWest Midlands

EastLondon

South EastSouth West

0 20 40 60 80 1005-year relative survival (%)

Part 2 Analysis: Non-standardised

Cases diagnosed 1991-95

COLON (Males)COLON

Men diagnosed 1991-95

UK and R IRELANDSCOTLAND

WALESN IRELANDR IRELANDENGLANDNorth East

North WestYorkshire Hum.

East MidlandsWest Midlands

EastLondon

South EastSouth West

0 20 40 60 80 1005-year relative survival (%)

Part 2 Analysis: Non-standardised

Cases diagnosed 1991-95

COLON (Males)

UK and R IRELANDSCOTLAND

WALESN IRELANDR IRELANDENGLANDNorth East

North WestYorkshire Hum.

East MidlandsWest Midlands

EastLondon

South EastSouth West

0 20 40 60 80 1005-year relative survival (%)

Part 2 Analysis: Non-standardised

Cases diagnosed 1996-99

COLON (Males)

Colon, men diagnosed 1991-95

Colon, men diagnosed 1996-99

SUMMARY

Preliminary results

Discussion between cancer registries about potential differences in:

•registering and coding cancer records (non-malignant cases, zero survival, multiples, …)

•health care