Cancer Outcomes 2012

C a n C e r O u t C O m e s2 0 1 2

4-10 // Outcomes Data

12 // Colorado’s Only Federally Designated Cancer Center

ta bl e Of C O n t e n t s

4 // Colon Cancer 5–Year Survival

4 // Liver Cancer 5–Year Survival

5 // Lung & Bronchus 5–Year Survival

5 // Melanoma of the Skin 5 –Year Survival

6 // Breast Cancer 5–Year Survival

6 // Corpus Uteri Cancer 5 –Year Survival

7 // Thyroid Cancer 5–Year Survival

7 // Prostate Cancer 5–Year Survival

8 // Brain (Excluding Benign Brain) 5–Year Survival

8 // Brain (GBM Only) 5 –Year Survival

9 // Pituitary Gland 5–Year Survival

3

university Of COlOradO HOspital is tHe leading aCademiC mediCal Center in tHe natiOn.

University of Colorado Hospital (UCH) is recognized as the highest-performing academic hospital in the United

States for delivering quality health care by the University HealthSystem Consortium for two years in a row, and is

ranked as the best hospital in the Denver metro area and one of the best in the country by U.S. News & World Report.

UCH is best known as an innovator in patient care and often is one of the first hospitals to bring new medicine to the

patient’s bedside. The hospital’s physicians are affiliated with the University of Colorado School of Medicine, part of

the University of Colorado system. Based at the expansive Anschutz Medical Campus in Aurora, Colo., UCH is where

patient care, research and education converge to establish the future of health care delivery.

4

Ou t C Ome s d ata

*N = 11 for UCH

*N = 16, **N = 19

*N = 11, **N = 14

55%

27%

15% 12%

34% 33%

12%

4%

47%

25%

14%

3%

Stage I* Stage II Stage III Stage IV

Esophagus Cancer - 5 Year Survival

UCH State National

88%

76%

58%

19%

73% 67%

54%

9%

78% 67%

55%

10%

Stage I* Stage II Stage III** Stage IV

Colon Cancer - 5 Year Survival

UCH State National

63%

50% 61%

14%

70%

57% 63%

9%

79%

64% 59%

11%

Stage I* Stage II** Stage III Stage IV

Rectum & RectoSigmoid Junction Cancer - 5 Year Survival

UCH State National

*N = 11

*NA, ** = 19

49% 51%

12% 18%

33%

25%

4% 2%

32%

25%

6% 2%

Stage I Stage II Stage III Stage IV*

Liver

UCH State National

13%

0%

3%

19%

7% 4%

2%

19%

10%

2% 2%

Stage I* Stage II Stage III** Stage IV

Pancreas Cancer - 5 Year Survival

UCH State National

l i v e r C a n C e r 5 – y e a r s u r v i v a l

C O l O n C a n C e r 5 – y e a r s u r v i v a l

*N = 16, **N = 19

*N = 11

UCH

Colorado

National

K e y

O b s e r v e d s u r v i v a l d a t a 2 0 0 3 - 2 0 0 5

( a J C C 6 t H e d i t i O n )

5

*N = 14

56%

36%

18%

6%

46%

31%

11%

3%

45%

26%

11%

2%

Stage I Stage II Stage III Stage IV

Lung & Bronchus Cancer - 5 Year Survival

UCH State National

92%

68% 65%

7%

90%

68% 59%

8%

91%

66%

55%

13%


Melanoma of the Skin - 5 Year Survival

UCH State National

Breast Cancer - 5 Year Survival

*N = 14

60%

30%

18%

6%

46%

31%

11%

3%

44%

26%

11%

2%


Lung & Bronchus Cancer - 5 Year Survival

UCH State National

92%

68% 65%

7%

90%

68% 59%

8%

91%

66%

55%

13%


Melanoma of the Skin - 5 Year Survival

UCH State National


Stage III Stage IVStage IIStage I

56%

46% 45%

36%31%

26%

18%

11% 11%7%

3% 2%

l u n g & b r O n C H u s 5 – y e a r s u r v i v a l

m e l a n O m a O f t H e s K i n 5 – y e a r s u r v i v a l

*N = 14

6

OU T C OME S d aTa

*N = 13, **N = 12

96% 90%

59% 47%

92% 85%

69%

26%

92% 85%

66%

21%



UCH State National

89%

77% 71%

33%

89%

76%

62%

23%

88%

72%

52%

16%

Stage I Stage II* Stage III Stage IV**

Corpus Uteri Cancer - 5 year Survival

UCH State National

*N = 13, **N = 12

96% 90%

59% 47%

92% 85%

69%

26%

92% 85%

66%

21%



UCH State National

89%

77% 71%

33%

89%

76%

62%

23%

88%

72%

52%

16%

Stage I Stage II* Stage III Stage IV**

Corpus Uteri Cancer - 5 year Survival

UCH State National

b r e a s t C a n C e r 5 – y e a r s u r v i v a l

C O r p u s u t e r i C a n C e r 5 – y e a r s u r v i v a l

*N = 13, **N = 12

UCH

Colorado

National

K e y



7

*N = 16

*N = 16

94% 95% 93%

47%

83% 89% 93%

35%

83% 91% 91%

37%


Prostate Cancer - 5 Year Survival

UCH State National

96% 86%

100%

68%

98% 97% 94%

57%

98% 96% 92%

59%

Stage I Stage II* Stage III* Stage IV

Thyroid Cancer - 5 Year Survival

UCH State National

*N = 16

*N = 16

94% 95% 93%

47%

83% 89% 93%

35%

83% 91% 91%

37%


Prostate Cancer - 5 Year Survival

UCH State National

96% 86%

100%

68%

98% 97% 94%

57%

98% 96% 92%

59%

Stage I Stage II* Stage III* Stage IV

Thyroid Cancer - 5 Year Survival

UCH State National

p r O s t a t e C a n C e r 5 – y e a r s u r v i v a l

t H y r O i d C a n C e r 5– y e a r s u r v i v a l

*N = 16

*N = 16

8

OU T C OME S d aTa

49%

26%

12% 11% 11%

36%

14% 7% 5% 4%

Year 1 Year 2 Year 3 Year 4 Year 5

Brain - GBM Only 5 Year Survival

UCH State

70%

57% 49% 46% 45%

56%

43% 37% 35% 32%


Brain (excluding Benign Brain) 5 Year Survival

UCH State

99% 98% 98% 98%

94% 96%

94% 93% 93%

89%


Pituitary Gland 5 Year Survival

UCH State

b r a i n ( g b m O n l y ) 5 – y e a r s u r v i v a l

b r a i n ( e x C l u d i n g b e n i g n b r a i n ) 5– y e a r s u r v i v a lComparable national data for this type not available

UCH

ColoradoK e y



9

70%

57% 49% 46% 45%

56%

43% 37% 35% 32%


Brain (excluding Benign Brain) 5 Year Survival

UCH State

99% 98% 98% 98%

94% 96%

94% 93% 93%

89%


Pituitary Gland 5 Year Survival

UCH State

p i t u i t a r y g l a n d 5 – y e a r s u r v i v a lComparable national data for this type not available

10

The University of Colorado Cancer Center is the hub of cancer research in Colorado. We are a consortium of more

than 400 researchers and physicians at three state universities and six institutions, all working toward one goal:

translating science into cancer survivorship.

C O l O r a d O ’ s O n l y f e d e r a l l y d e s i g n a t e d C a n C e r C e n t e r t a C K l e s C a n C e r f r O m a l l a n g l e s

NCI CANCER CENTERS IN THE USA

= NCI Cancer Center

= NCI Comprehensive Cancer Center

= UCH, NCI Comprehensive Cancer Center

11

Through collaboration and innovation, CU Cancer Center

members discover, develop and deliver breakthroughs that improve

cancer care for people and companion animals. We focus on:

Personalized care that embraces the best clinical practices of

prevention, diagnosis, treatment and survivorship.

• Innovative interdisciplinary research.

• Premier clinical and scientific training.

• Creative partnerships.

Founded in 1988, CU Cancer Center is the only comprehensive

cancer center designated by the National Cancer Institute in

Colorado and the Rocky Mountain region. Our founding director,

Paul A. Bunn, Jr., MD, led the organization until 2009. In 2010, Dan

Theodorescu, MD, PhD, ushered CU Cancer Center into a new era.

CU Cancer Center is headquartered on the Anschutz Medical

Campus in Aurora, Colo., in the University of Colorado School of

Medicine. Member institutions include University of Colorado

Denver, University of Colorado Boulder, Colorado State

University, University of Colorado Hospital, Children’s Hospital

Colorado, Denver VA, Veterans Affairs Medical Center, Denver

Health, National Jewish Health and the Kaiser Permanente’s

Institute of Health Research. Our clinical outreach program

extends throughout Colorado and neighboring states.

HigHl igH t s a nd a C C Omp l i s Hme n t sCU Cancer Center is known clinically for its robust and diverse

Phase I clinical trials program and personalized cancer

treatment. Our scientific expertise ranges from understanding

how chromosome structure controls cancer cell behavior, to

understanding how the immune system impacts cancer. Other

strengths include:

Lung cancer care and research. CU Cancer Center is one of

the world’s best lung cancer research and treatment programs.

We are the coordinating center for the Lung Cancer Mutations

Consortium, funded by a $5.3 million American Reinvestment

and Recovery Act Grand Opportunities grant.

Cancer survivorship. We’re one of eight LIVESTRONG Cancer

Survivorship Centers of Excellence and home to the region’s

three full-scale cancer survivorship clinics: The HOPE clinic for

young adult survivors of cancer at Children’s Hospital Colorado,

the TACTIC clinic for adult survivors of childhood cancer at

University of Colorado Hospital, and the THRIVE clinic for

transitioning adult cancer patients back to primary care.

Cancer screening. The Colorado Colorectal Screening Program

is a national model for ensuring uninsured Coloradans who meet

certain financial and risk criteria receive colon cancer screening

and follow-up care at no cost to them.

Molecular tumor testing. CU Cancer Center has developed

tests that find specific gene defects that can be targeted with

new drugs. These tests have positioned CU Cancer Center as a

national leader for clinical trials of “targeted” drugs.

Tumor Explants. CU Cancer Center is on the cutting edge of

personalized cancer treatment, developing laboratory methods

to test cancer therapy by explanting living cancers from patients

into a special breed of mice. The mice receive different treatments

to identify the drug combination that the patient’s tumor will best

respond to.

Cancer clinical trials. With the largest human and companion

animal cancer clinical trials programs in the region, CU Cancer

Center provides patients across the state and region with access

to cutting-edge cancer care. CU Cancer Center’s Phase I Trials

program is the only program of its kind in the region.

Structural biology. CU Cancer Center’s NMR spectroscopy and

X-ray facilities are among the best in the world and have helped

recruit world-class scientists to use them. The machines, housed

in CU Cancer Center’s Structural Biology shared resource, help

scientists solve structures of cancer molecules to develop drugs

with precise molecular targeting.

Animal cancer treatment and clinical trials. The Colorado

State University Animal Cancer Center is the world leader in

research and treatment of spontaneously occurring cancers

in companion animals, especially dogs. CU Cancer Center’s

members at CSU collaborate with researchers in human cancers,

and clinical trials in dogs have led to new treatments for people.

l e a r n mOr e :www.coloradocancercenter.org

www.uch.edu

coloradocancerblogs.org

facebook.com/coloradocancercenter

Cancer Outcomes 2012

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