BRAINSTEM-Lec by Emma

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    BRAINSTEM

    Lecturer: Emmaruth B. Bautista, PTRP

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    MEDULLA OBLONGATA

    Upper half- cavity of 4

    th

    ventricleLower half- central canal of SC

    ANTERIOR SURFACE OF MEDULLA:AMF- anterior median fissure of SC

    PYRAMIDS- one ach side of AMF of SC

    Swelling Tapers inferiorly: bundles of nerve fibers,

    corticospinal tracts

    DECUSSATION OF PYRAMIDS

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    1. Anteriormedian fissure

    2. Olive

    3. Pyramids 4.Cerebellum

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    MEDULLA OBLONGATA

    OLIVES- posterolateral to pyramidsGroove between PYRAMIDS & OLIVE:

    Rootlets ofHYPOGLOSSAL N.

    INFERIOR CEREBELLAR PEDUNCLES-Posterior to olives

    Connects MO-cerebellum

    Groove between OLIVES & INFERIORCEREBELLAR PEDUNCLES:

    Rootlets ofGLOSSOPHARYNGEAL, VAGUS &

    CRANIAL ROOTS OF ACCESSORY N.

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    1.Glossopharyngeal

    nerve

    2.Vagus nerve 3.Hypoglossal nerve

    4.Accessory nerve

    5.First cervical spinal

    nerve

    6.Spinal root of accessory

    nerve

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    MEDULLA OBLONGATA

    POSTERIOR SURFACE OF Medulla Oblongata:Superior half- forms lower part of floor of 4th

    ventricle

    Inferior half- continuous with SC & possesses

    posterior median sulcusGRACILE TUBERCLE- on each side of posterior

    median sulcus

    Elongated swellingProduced by GRACILE NUCLEUS

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    MEDULLA OBLONGATA

    CUNEATE TUBERCLE- lateral to gracile nucleusProduced by underlying: CUNEATE

    Internal Structure:Considered at 4 levels:

    1. pyramids

    2. lemnisci

    3. olives

    4. just inferior to pons

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    LEVEL OF DECUSSATION OF

    PYRAMIDS

    Great motor decussationSuperior part of MO: corticospinal fibers occupy &

    form the pyramid

    Inferiorly: about of fibers cross median plane &continue down the SC in the lateral white column as

    LATERAL CORTICOSPINAL TRACT ( crosses

    midline )

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    FASCICULUS GRACILLIS &

    CUNEATUSContinue to ascend superiorly posterior to central

    gray matter

    Appears as posterior extensions of central gray

    matter

    Substantia gelatinosa in posterior gray column

    becomes continuous with inferior end ofNUCLEUS

    OF SPINAL TRACT OF TRIGEMINAL N.

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    LEVEL OF DECUSSATION OF

    LEMNISCI

    Great sensory decussationTakes place anterior to central gray matter &

    posterior to pyramids

    Have bee formed from: INTERNAL ARCUATE

    FIBERS

    Which has emerged from the anterior aspect of

    the NUCLEUS GRACILIS & NUCLEUS

    CUNEATUS

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    LEVEL OF DECUSSATION OF

    LEMNISCI

    NUCLEUS OF SPINAL TRACT OF TRIGEMINALN.-

    lies lateral to internal arcuate fibers

    SPINAL TRACT OF TRIGEMINAL N.- Lies lateral to nucleus

    LATERAL & ANTERIOR SPINOTHALAMIC

    TRACTS & TECTAL TRACTS

    Lateral to decussation of lemnisci

    Collectively known as: SPINAL LEMNISCUS

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    LEVEL OF DECUSSATION OF

    LEMNISCI

    SPINOCEREBELLAR, VESTIBULOSPINAL &RUBROSPINAL TRACTS-

    Situated anterolateral region of Medulla Oblongata

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    LEVEL OF OLIVESTransverse section passes across inferior part of 4th

    ventricle

    Amount of gray matter has increased at this level

    OLIVARY NUCLEAR COMPLEX:

    INFERIOR OLIVARY NUCLEUS Largest nucleus of this complex

    Gray matter shaped-bag, mouth directed mediallyResponsible for elevation on surface of medulla called

    OLIVES

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    OLIVARY NUCLEAR COMPLEX

    Smaller dorsal & medial accessory olivary nuclei

    are also present

    Send fibers medially across midline to enter

    cerebellumSPINO-OLIVARY TRACTS

    Function is associated with voluntary movement

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    VESTIBULOCOCHLEAR NUCLEIVESTIBULAR COMPLEX:

    1. medial vestibular nucleus

    2. inferior vestibular nucleus

    3. lateral vestibular nucleus

    4. superior vestibular nucleus

    2 COCHLEAR NUCLEI:

    1. anterior cochlear ( anterolat of ICP )

    2. posterior cochlear ( post of ICP )

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    NUCLEUS AMBIGUUS

    Large motor neurons

    Situated deep w/in reticular formation

    Joins CN IX, X, XI ( cranial part ) distributed to

    voluntary muscles

    CENTRAL GRAY MATTER

    Lies beneath floor of 4th ventricle ( M-L )

    1. hypoglossal nucleus 2. dorsal nucleus of vagus

    3. nucleus of tractus solitarius

    4. medial & inferior vestibular nuclei

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    ARCUATE NUCLEI

    Inferior displaced pontine nuclei

    Efferent fibers to cerebellum- EXTERNALARCUATE FIBERS

    PYRAMIDS CORTICOSPINAL & CORTICONUCLEAR FIBERS

    MEDIAL LEMNISCUS Flattened tracts on each side of midline posterior to pyramid

    Emerge from decussation of lemnisci

    Convey sensory information to thalamus

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    MEDIAL LONGITUDINAL FASCICULUS

    Forms small tract of fibers situated on each side of

    midline posterior to medial lemniscus & anterior tohypoglossal nucleus

    INFERIOR CEREBELLAR PEDUNCLES In posterolateral corner on lateral side of 4th ventricle

    SPINAL TRACT OF CN V & ITS NUCLEUS On antermedial aspect of ICP

    ANTERTIOR SPINOCEREBELLAR TRACT

    Between inferior olivary & nucleusof spinal tract of CN VRETICULAR FORMATION

    Deep posterior to olivary nucleus

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    1.Nuclei of oculomotor

    nerve

    2.Trochlear nucleus

    3.Pons 4.Fourth ventricle

    5.Abducent nucleus

    6.Vestibular nucleus

    7.Medial longitudinal

    fasciculus

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    1.Inferior cerebellar

    peduncle

    2.Floor of fourth ventricle

    3.Hypoglossal nucleus 4.Medial longitudinal

    fasciculus

    5.Reticular formation

    6.Medial lemniscus

    7.Arcuate nuclei

    8.Inferior olivary nucleus

    9.Pyramids

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    IX, X & Cranial part of Accessory N.

    can be seen running forward & lateral through

    reticular formation

    HYPOGLOSSAL N.

    Run anterior & lateral through reticular

    LEVEL JUST INFERIOR TO PONSNo major changes

    Lateral vestibular nucleus has replaced

    inferior vestibular nucleus

    Cochlear nucleus now are visible on anterior

    & posterior surface of ICP

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    PONSGROSS APPEARANCE:

    Convex anterior surface

    Transverse fibers converge to form MCP

    BASILAR GROOVE

    lodges basilar artery

    On anterolat side: emerges CN V on each side

    Motor root: smaller, medial part

    Sensory root: larger, lateral part

    Groove between PONS & MO ( M-L )

    CN VI, VII, VIII

    1 Cerebral peduncle

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    1.Cerebral peduncle

    2.Basilar groove

    3.Olive

    4.Pyramid 5.Trigeminal nerve

    6.Abducent nerve

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    POSTERIOR SURFACE:

    Limited laterally by SCP

    MEDIAN SULCUS- divides pons symmetrically MEDIAL EMINENCE-

    Bounded by sulcus limitans

    Lateral to sulcus

    FACIAL COLLICULUS Slight expansion on inferior end of medial eminence

    SUBSTANTIA FERRUGINEA

    Bluish gray in superior part of sulcus limitans

    AREA VESTIBULI

    Lateral to sulcus limitans

    Underlying vestibular nuclei

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    1.Substantia ferruginea

    2.Facial colliculus

    3.Striae medullares

    4.Vestibular area 5.Hypoglossal triangle

    6.Vagal triangle

    7.Calamus scriptorius

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    INTERNAL STRUCTURE OF PONS:Divided into:

    TEGMENTUM- posterior part BASAL PART- anterior part TRAPEZOID BODY- divides tegmentum & basal part

    TRANSVERSE SECTION THROUGH CAUDAL

    PART:Medial LemniscusFacial NucleusNucleus of abducent nerve

    Facial colliculusMedial longitudinal fasciculusMedial vestibular nucleusPosterior & anterior cochlear nuclei

    Spinal nucleus of CN V

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    TRAPEZOID BODY Fibers derived from cochlear nuclei & nuclei of trapezoid

    body

    BASILAR PART OF PONS:

    Contains small masses of nerve cells: PONTINE

    NUCLEICORTICOPONTINE FIBERS of crus cerebri

    terminate in pontine nuclei

    TRANSVERSE FIBERS enter middle cerebellar

    peduncle

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    TRANSVERSE SECTION THROUGH

    CRANIAL PART

    Motor nucleus of trigeminal nerve

    Principal sensory nucleus of trigeminal nerve

    Superior cerebellar peduncleAnterior cerebellar tract

    Trapezoid body

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    MIDBRAIN

    CEREBRAL AQUEDUCTNarrow channel traversing midbrain

    Filled with CSF

    POSTERIOR SURFACE OF MIDBRAIN:COLLICULI ( Corpora Quadrigemina )

    Rounded eminences divided into superior &

    inferior pairs by a vertical & transverse groove.

    SUPERIOR COLLICULI- centers for visual

    reflexes

    INFERIOR COLLICULI- lower auditory centers

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    TROCHLEAR- emerges in the midline below

    inferior colliculi

    LATERAL ASPECT OF MIDBRAIN:SUPERIOR BRACHIUM

    Passes from superior colliculus to lateralgeniculate body & optic tract

    INFERIOR BRACHIUM

    Connects inferior colliculus to:MEDIAL GENICULATE BODY

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    ANTERIOR ASPECT OF MIDBRAIN:

    INTERPENDICULAR FOSSA

    Deep depression in the midline, bound on eachside by:

    CRUS CEREBRI

    POSTERIOR PERFORATED SUBSTANCEMany small blood vessels that perforate the floor

    of the interpendicular fossa

    OCCULOMOTOR NERVEemerges from agroove on medial side of crus cerebri & passes

    forward in lateral wall of cavernous sinus

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    INTERNAL STRUCTURE OF MIDBRAIN:Midbrain comprises 2 lateral halves:

    CEREBRAL PEDUNCLES, each divided into:CRUS CEREBRI- anterior part &TEGMENTUM- posterior part by:SUBSTANTIA NIGRA- pigmented band of gray

    matterCEREBRAL AQUEDUCT- narrow cavity w/c

    connects 3rd & 4th ventricle

    TECTUM- part of midbrain posterior to cerebralaqueduct & has 4 swellings: 2 SUPERIOR COLLICULI 2 INFERIOR COLLICULI

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    TRANSVERSE SECTION OF MB AT

    LEVEL OF INFERIOR COLLICULI

    INFERIOR COLLICULUSTROCHLEAR NUCLEUS

    Situated in gray matter close to median plane just

    posterior to the: MEDIAL LONGITUDINALFASCICULUS

    MESENCEPHALIC NUCLEI OF CN V are lateralto cerebral aqueduct

    DECUSSATION OF SUPERIOR CEREBELLARPEDUNCLES

    Occupies central part of tegmentum anterior to

    cerebral aqueduct

    RETICULAR FORMATION

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    RETICULAR FORMATIONMEDIAL LEMNISCUS

    Ascends posterior to substantia nigra

    SPINAL & TRIGEMINAL LEMNISCI Situated lateral to medial lemniscus

    LATERAL LEMNISCUS Posterior to trigeminal lemniscus

    SUBSTANTIA NIGRA Large motor nucleus situated between tegmentum & crus

    cerebri Concerned w/ mm tone, connected to Cerebral cortex, SC,

    hypothalamus & basal nucleiCRUS CEREBRI

    Coticospinal & corticonuclear occupy middle 2/3of crus Frontopontine fibers on lateral part

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    TRANSVERSE SECTION OF MB AT

    LEVEL OF SUPERIOR COLLICULI

    SUPERIOR COLLICULUS

    LIGHT REFLEX- PRETECTAL NUCLEUS

    OCCULOMOTOR NUCLEUS situated in centralgray matter close to median plane, just posteriortoMEDIAL LONGITUDINAL FASCICULUS

    MEDIAL, SPINAL & TRIGEMINAL LEMNISCI

    Form a curved band posterior to substantia nigra butLATERAL LEMNISCUS does not extend superiorly to

    this level

    1 Pi l l d

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    1.Pineal gland

    2.superior colliculus

    3.Inferior colliculus

    4.Trochlear nerve 5.Fourth ventricle

    6.Pulvinar of thalamus

    7.Superior cerebellar

    peduncle

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    RED NUCLEUS

    Rounded mass of gray matter situated between

    cerebral aqueduct & substantia nigraRedish hue is due to its vascularity & presence

    of iron containing pigment in cytoplasm ot its

    neurons.

    RETICULAR FORMATION

    Situated in tegmentum lateral & posterior to red

    nucleus

    CRUS CEREBRI Contains identical, important descending tracts:

    CORTICOSPINAL, CORTICONUCLEAR,

    CORTICOPONTINE fibers

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    BRAINSTEM STROKE

    SYNDROMESTWO GENERAL MANIFESTATIONS

    EXPECTED OF A BRAINSTEM STROKE: 1. Contralateral hemiplegia

    2. Ipsilateral Cranial Nerve Palsy

    Also known as ALTERNATING/ CROSSED

    HEMIPLEGIA

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    WEBERS SYNDROME

    MEDIAL BASAL MIDBRAIN

    Contralateral Hemiplegia

    Ipsilateral CN 3 Palsy( Ipsilateral Ptosis )

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    BENEDIKTS SYNDROME

    TEGMENTUM OF MIDBRAINCONTRALATERAL:

    Pain & temperature loss

    Joint position loss Ataxia

    Chorea

    IPSILATERAL:CN 3 palsy

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    LOCKED IN SYNDROME

    BILATERAL PONS

    Bilateral Hemiplegia

    Bilateral CN Palsy

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    WALLENBERGS or LATERAL

    MEDULLARY SYNDROME

    LATERAL MEDULLA

    IPSILATERAL:Loss of FACIAL SENSATION

    Hemiataxia

    Horners syndrome

    Nystagmus

    dysphagia

    CONTRALATERALLoss of pain & temperature

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    LEFT VS. RIGHT CVALEFT BRAIN FUNCTIONS

    Language/Communications

    Higher skill

    logic

    RIGHT BRAIN FUNCTIONS Perception

    Imagination

    Memory

    The arts & music

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    LEFT VS. RIGHT CVA

    LEFT CVA a.k.a : Left hemispheric lesion

    Dominant hemispheric lesion or CVA

    Right hemiplegic

    RIGHT CVA a.k.a :Right hemispheric lesion

    Non-dominant Hemispheric lesion or CVA

    Left hemiplegic

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