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    BRAIN PORT VISION TECHNOLOGY

    1. The voice for the Blind

    1.1 INTRODUCTION:-

    Brain Port is a technology where by sensory information can be sent to one's brain via a

    signal from the Brain Port (and its associated sensor) that terminates in an electrode array which

    sits atop the tongue. It was initially developed by Paul Bach-y-Rita as an aid to people's sense of

    balance, particularly of stroke victims. Brain Port technology has been developed for use as a

    visual aid. For example, the Brain Port has demonstrated its ability to allow a blind person to see

    his surroundings in polygonal and pixel form. In this scenario, a camera picks up the image of

    the surrounding; the information is processed by a chip which converts it into impulses which are

    sent through an electrode array, via the tongue, to the person's brain. The human brain is able to

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    interpret these impulses as visual signals and they are then redirected to the visual cortex,

    allowing the person to see. Brain Port technology is based on the phenomenon of sensory

    substitution. For the vision application, visual information is perceived via the sense of touch on

    the human tongue. Well, not exactly through her tongue, but the device in her mouth sent visual

    input through her tongue in much the same way that seeing individuals receive visual input

    through the eyes. All sensory information sent to the brain is carried by nerve fibers in the form

    of patterns of impulses, and the impulses end up in the different sensory centers of the brain for

    interpretation. To substitute one sensory input channel for another, you need to correctly encode

    the nerve signals for the sensory event and send them to the brain through the alternate channel.

    The brain appears to be flexible when it comes to interpreting sensory input. You can train it to

    read input from, say, the tactile channel, as visual or balance information, and to act on it

    accordingly. In JS On line's "Device may be new pathway to the brain,

    What is the Brain Port vision device?

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    The Brain Port vision device is an investigational non-surgical assistive visual prosthetic

    device that translates information from a digital video camera to your tongue, through gentle

    electrical stimulation. The Brain Port vision system consists of a postage-stamp-size electrode

    array for the top surface of the tongue (the tongue array), a base unit, a digital video camera, and

    a hand-held controller for zoom and contrast inversion. Visual information is collected from the

    user-adjustable head-mounted camera (FOV range 390 degrees) and sent to the BrainPort base

    unit. The base unit translates the visual information into an stimulation pattern that is displayed

    on the tongue. The tactile image is created by presenting white pixels from the camera as strong

    stimulation, black pixels as no stimulation, and gray levels as medium levels of stimulation, with

    the ability to invert contrast when appropriate. Users often report the sensation as pictures that

    are painted on the tongue with Champagne bubbles. With the current system (arrays containing

    100 to 600+ electrodes), study participants have been able to recognize high-contrast objects,

    their location, movement, and some aspects of perspective and depth. Trained blind participants

    use information from the tongue display to augment understanding of the environment. Ongoing

    research with the Brain Port vision device demonstrates the great potential of tactile vision

    augmentation and we believe that these findings warrant further exploration.

    Parts of brain port:

    Brain Port uses the tongue instead of the fingertips, abdomen or back used by othersystems. The tongue is more sensitive than other skin areas -- the nerve fibers are closer to the

    surface, there are more of them and there is no stratum corneum (an outer layer of dead skin

    cells) to act as an insulator. It requires less voltage to stimulate nerve fibers in the tongue -- 5 to

    15 volts compared to 40 to 500 volts for areas like the fingertips or abdomen. Also, saliva

    contains electrolytes, free ions that act as electrical conductors, so it helps maintain the flow of

    current between the electrode and the skin tissue. And the area of the cerebral cortex that

    interprets touch data from the tongue is larger than the areas serving other body parts, so the

    tongue is a natural choice for conveying tactile-based data to the brain.

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    An accelerometer is a device that measures,

    among other things, tilt with respect to the pull

    of gravity. The accelerometer on the underside

    of the 10-by-10 electrode array transmits data

    about head position to the CPU through the

    communication circuitry. When the head tilts

    right, the CPU receives the "right" data and

    sends a signal telling the electrode array to

    provide current to the right side of the wearer's

    tongue. When the head tilts left, the device

    buzzes the left side of the tongue. When the

    head is level, Brain Port sends a pulse to the

    middle of the tongue. After multiple sessions

    with the device, the subject's brain starts to pick

    up on the signals as indicating head position --

    balance information that normally comes from

    the inner ear -- instead of just tactile

    information. From the CPU, the signals are

    sent to the tongue via a "lollipop," an electrode

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    array about nine square centimeters that sits directly on the tongue. Each electrode corresponds

    to a set of pixels. White pixels yield a strong electrical pulse, whereas black pixels translate into

    no signal. Densely packed nerves at the tongue surface receive the incoming electrical signals,

    which feel a little like Pop Rocks or champagne bubbles to the user. A dental-retainer-like unit

    would house a battery, the electrode array and all of the microelectronics necessary for signal

    encoding and transmitting. In the case of the Brain Port vision device, the electronics might be

    completely embedded in a pair of glasses along with a tiny camera and radio transmitter, and the

    mouthpiece would house a radio receiver to receive encoded signals from the glasses. It's not

    exactly a system on a chip.

    1.2WORKING OF BRAIN PORT:-

    To produce tactile vision, Brain Port uses a camera to capture visual data. The optical

    information -- light that would normally hit the retina -- that the camera picks up is in digital

    form, and it uses radio signals to send the ones and zeroes to the CPU for encoding. Each set of

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    pixels in the camera's light sensor corresponds to an electrode in the array. The CPU runs a

    program that turns the camera's electrical information into a spatially encoded signal. The

    encoded signal represents differences in pixel data as differences in pulse characteristics such as

    frequency, amplitude and duration. Multidimensional image information takes the form of

    variances in pulse current or voltage, pulse duration, intervals between pulses and the number of

    pulses in a burst, among other parameters. To the extent that a trained user may simultaneously

    distinguish between multiple of these characteristics of amplitude, width and frequency, the

    pulses may convey multidimensional information in much the same way that the eye perceives

    color from the independent stimulation of different color receptors. The electrode array receives

    the resulting signal via the stimulation circuitry and applies it to the tongue. The brain eventually

    learns to interpret and use the information coming from the tongue as if it were coming from the

    eyes.

    An experience (research) of a blind woman who go to see the world with the help of

    this evolutionary device BRAINPORT:

    A blind woman sits in a chair holding a video camera focused on a scientist sitting in front of

    her. She has a device in her mouth, touching her tongue, and there are wires running from that

    device to the video camera. The woman has been blind since birth and doesn't really know what

    a rubber ball looks like, but the scientist is holding one, and when he suddenly rolls it in her

    direction, she puts out a hand to stop it. The blind woman saw the ball through her tongue. Well,

    not exactly through her tongue, but the device in her mouth sent visual input through her tongue

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    in much the same way that seeing individuals receive visual input through the eyes. In both

    cases, the initial sensory input mechanism the tongue or the eyes send the visual data to

    the brain, where that data is processed and interpreted to form images.

    1.3 CONCEPT OF ELECRTICALSTIMULATION:-

    Electro tactile stimulation for sensory augmentation orsubstitution, an area of study that involves

    using encoded electric current to represent sensory information that a person cannot receive through the

    traditional channel and applying that current to the skin, which sends the information to the brain. The

    brain then learns to interpret that sensory information as if it were being sent through the traditional

    channel for such data. Most of us are familiar with the augmentation or substitution of one sense for

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    another. Eyeglasses are a typical example of sensory augmentation. Braille is a typical example of

    sensory substitution -- in this case, you're using one sense, touch, to take in information normally intended

    for another sense, vision. Electro tactile stimulation is a higher-tech method of receiving somewhat

    similar (although more surprising) results, and it's based on the idea that the brain can interpret sensory

    information even if it's not provided via the "natural" channel.

    The idea is to communicate non-tactile information via electrical stimulation of the sense

    of touch. In practice, this typically means that an array of electrodes receiving input from a non-

    tactile information source (a camera, for instance) applies small, controlled, painless currents

    (some subjects report it feeling something like soda bubbles) to the skin at precise locations

    according to an encoded pattern. The encoding of the electrical pattern essentially attempts to

    mimic the input that would normally be received by the non-functioning sense. So patterns

    of light picked up by a camera to form an image, replacing the perception of the eyes, are

    converted into electrical pulses that represent those patterns of light. When the encoded pulses

    are applied to the skin, the skin is actually receiving image data those nerve fibers forward their

    image-encoded touch signals to the tactile-sensory area of the cerebral cortex, the parietal lobe.

    Within this system, arrays of electrodes can be used to communicate non-touch information

    through pathways to the brain normally used for touch-related impulses.

    The multiple channels that carry sensory information to the brain, from the eyes, ears and

    skin, for instance, are set up in a similar manner to perform similar activities. All sensory

    information sent to the brain is carried by nerve fibers in the form ofpatterns of impulses, and

    the impulses end up in the different sensory centers of the brain for interpretation. To substitute

    one sensory input channel for another, you need to correctly encode the nerve signals for the

    sensory event and send them to the brain through the alternate channel. The brain appears to be

    flexible when it comes to interpreting sensory input. You can train it to read input from, say, the

    tactile channel, as visual or balance information, and to act on it accordingly. In JS Online's

    "Device may be new pathway to the brain," University of Wisconsin biomedical engineer and

    Brain Port technology co-inventor Mitch Tyler states, "It's a great mystery as to how that processtakes place, but the brain can do it if you give it the right information." Action potentials (AP's)

    thus recorded had amplitudes from 0.1 to 1.0 mV and a 5 : 1 signal-to-noise ratio (SNR).A

    circular electrode surrounding the recording site served as the ground reference. Following pre

    amplification and band pass filtering (200-10 000 Hz), a differential amplitude detector

    identified AP's, producing an output pulse whenever the recorded signal entered a predefined

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    amplitude-time window. In the first experiment, electro tactile entrainment currents (iEN) were

    determined by adjusting the stimulation current from near zero to the minimal value resulting in

    one AP for each stimulation pulse. These currents exceeded the absolute thresholds (the currents

    causing occasional AP's) by approximately 5%. The entrainment current was determined twice

    for positive- and negative-polarity stimulation pulses of ten different widths: 20, 30, 40, 50, 70,

    100, 150, 200, 300, and 500 _s, delivered at a rate of 10 pulses/s. The width sequence was

    reversed during the second run on each of the three fibers.

    Relative timing between simultaneous mechanical and electrotactile stimulation.

    The top trace represents the sinusoidal, 30-Hz, 50-100-_m (0-P) mechanical displacement.

    1.4WHAT BRAINPORT USERS SEE:-

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    With the current prototype (arrays containing 100 to 600+ electrodes), study participants

    have recognized the location and movement of high-contrast objects and some aspects of

    perspective and depth. In most studies, participants use the device for between two and 10 hours,

    often achieving the following milestones:

    y Within minutes: users perceive where in space stimulation arises (up, down, left, andright) and the direction of movement

    y Within an hour: users can identify and reach for nearby objects, and point to and estimatethe distance of objects out of reach

    y Within several hours: users can identify letters and numbers and can recognize landmarkinformation.

    The device provides a new sensory language with which users learn to translate the impulse

    patterns on the tongue to objects in space. Neuro imaging research suggests that using BrainPort

    stimulates the visual regions of the brain in blind individuals.

    At present, Brain Port is an investigational prototype and not commercially available. A

    number of academic and research institutions have had or will have studies using the BrainPort

    Vision Device with specific participation requirements. Contact Wicab for more information.

    While Brain Port does not replace vision, it enhances the overall sensory experience and givesusers information on the size, shape, and location of objectsperception that will no doubt help

    blind and visually impaired persons move with greater independence and lead fuller lives. In any

    case, within 15 minutes of using the device, blind people can begin interpreting spatial

    information via the Brain Port, says William Seiple, research director at the nonprofit vision

    healthcare and research organization Lighthouse International. The electrodes spatially correlate

    with the pixels so that if the camera detects light fixtures in the middle of a dark hallway,

    electrical stimulations will occur along the center of the tongue.

    "It becomes a task of learning, no different than learning to ride a bike," Arnoldussen says,

    adding that the "process is similar to how a baby learns to see. Things may be strange at first,

    but over time they become familiar."

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    1.5 RESOLUTION:-

    The resolution of brain port camera varies according to the necessity. The images below

    demonstrate how information from the video camera is represented on the tongue. Today's

    prototypes have 400 to 600 points of information on a ~3cm x 3cm tongue display, presented at

    approximately 30 frames per second, yielding an information rich image stream. Our research

    suggests that the tongue is capable of resolving much higher resolution information and we are

    currently working to develop the optimal tongue display hardware and software.

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    1.6 APPLICATIONS:

    The Brain Port test results are somewhat astonishing and lead many to wonder about the

    scope of applications for the technology

    CURRENT APPLICATIONS:-

    The current or foreseeable medical applications include:

    y providing elements of sight for the visually impairedy providing sensory-motor training for stroke patientsy providing tactile information for a part of the body with nerve damagey alleviating balance problems, posture-stability problems and muscle rigidity in people

    with balance disorders and Parkinson's disease

    y enhancing the integration and interpretation of sensory information in autistic people

    POTENIAL APPLICATIONS:

    The Brain Port electrodes would receive input

    from a sonar device to provide not only directional

    cues but also a visual sense of obstacles and

    terrain. Military-navigation applications could

    extend to soldiers in the field when radio

    communication is dangerous or impossible or

    when their eyes, ears and hands are needed to

    manage other things -- things that might blow up.

    BrainPort may also provide expanded information for military pilots, such as a pulse on the

    tongue to indicate approaching aircraft or to indicate that they must take immediate action. With

    training, that pulse on their tongue could elicit a faster reaction time than a visual cue from a

    light on the dashboard, since the visual cue must be processed by the retina before it's forwarded

    to the brain for interpretation. Other potential Brain Port applications include robotic surgeries.

    The surgeon would wear electro tactile gloves to receive tactile input from robotic probes inside

    someone's chest cavity. In this way, the surgeon could feel what he's doing as he controls the

    robotic equipment. Race car drivers might use a version of Brain Port to train their brains for

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    faster reaction times, and gamers might use electro tactile feedback gloves or controllers

    tofeelwhat they're doing in a video game. A gaming Brain Port could also use a tactile-vision

    process to let gamers perceive additional information that isn't displayed on the screen.

    Brain Port is currently conducting a second round of clinical trials as it works its way

    through the FDA approval process for the balance device. The company estimates a commercial

    release in late 2006, with a roughly estimated selling price of $10,000 per unit. Brain Port

    envisions itself even smaller and less obtrusive in the future. In the case of the balance device, all

    of the electronics in the handheld part of the system might fit into a discreet mouthpiece.

    1.7 DISADVANTAGES:-

    The major disadvantage to the Brain Port is that you cant see and speak at the same time

    with the electric array (lollipop) in your mouth. Whatever you do, dont drive and speak on thephone while using this device at the same time.

    1.8 CONCLUSION:-

    Brain port is indeed one of the finest and useful technologies. This article offers insights and

    navigates the action about the pro and cons, of the brain port technology. Technology is a boon

    in biomedical and can work for all the field like defense, sports, robotics, spy gadgets, and is able

    to change the life of physically and mentally impaired persons. In comparison to biology,

    human-machine interface technology is in its early infancy.

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    REFERENCES:-

    Bach-y-Rita, Paul et al. "Form perception with a 49-point electrotactile stimulus array onthe tongue: A technical note." Journal of Rehabilitation Research and Development,

    1998.

    http://kaz.med.wisc.edu/Publications/1998-BachyRita-JRRD-Tongue.pdf

    Blakeslee, Sandra. "New Tools to Help Patients Reclaim Damaged Senses." New YorkTimes, Nov. 23, 2004.

    http://www.goupstate.com/apps/pbcs.dll/article?AID=/20041123/ZNYT05/411230391/10

    51/NEWS01

    Kaczmarek, Kurt, Ph.D. "Tongue Display Technology." University of Wisconsin, Aug.18, 2005.http://kaz.med.wisc.edu/Publicity/Synopsis.html

    Kupers, Ron et al. "Activation of visual cortex by electrotactile stimulation of the tonguein early-blind subjects." Human Brain Mapping 2003.

    http://208.164.121.55/hbm2003/abstract/abstract1557.htm

    Manning, Joe. "Device may be new pathway to the brain." JS Online, Dec. 7, 2004.http://www.jsonline.com/story/index.aspx?id=282145

    Phone interview with Kurt Kaczmarek, Ph.D., Senior Scientist, University of WisconsinDepartment of Orthopedics and Rehabilitation Medicine. July 7, 2006.

    Ptito, Maurice et al. "Cross-modal plasticity revealed by electrotactile stimulation of thetongue in the congenitally blind." Brain, 2005.

    http://brain.oxfordjournals.org/cgi/content/abstract/128/3/606

    U.S. Patent #6,430,450. "Tongue placed tactile output device." Wicab, Inc.

    http://www.wicab.com/

    "Wicab to present BrainPort at Boston conference." WTN News. Oct. 4, 2005.http://wistechnology.com/printarticle.php?id=2319