Bleeding Esophageal Varices
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Bleeding esophageal varices
Cirrhosis - dischargeBleeding esophageal varices are very swollen veins in the walls of the lower part of the esophagus(the tube that connects your throat to your stomach) that begin to bleed.
Causes
Scarring (cirrhosis) of the liver is the most common cause of esophageal varices. This scarringprevents blood from flowing through the liver. As a result, more blood flows through the veins of theesophagus.
This extra blood flow causes the veins in the esophagus to balloon outward. If these veins breakopen (rupture), they can cause severe bleeding.
Any cause of chronic liver disease can cause varices.
The swollen veins (varices) can also occur in the upper part of the stomach.
Symptoms
People with chronic liver disease and esophageal varices may have no symptoms.
If there is only a small amount of bleeding, the only symptom may be dark or black streaks in thestools.
If larger amounts of bleeding occur, symptoms may include:
Black, tarry stools
Bloody stools
Light-headedness Paleness
Symptoms of chronic liver disease (such as cirrhosis)
Vomiting
Vomiting blood
Exams and Tests
Physical examination:
Bloody or black stool on rectal exam
Low blood pressure
Rapid heart rate
Signs of chronic liver disease or cirrhosis
Tests to determine where the bleeding is coming from and detect active bleeding include:
Esophagogastroduodenoscopy (EGD)
Tube through the nose into the stomach (nasogastric tube) to look for signs of bleeding
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Some doctors recommend EGD for patients who are newly diagnosed with mild-to-moderatecirrhosis to screen for esophageal varices and treat them before there is bleeding.
Treatment
The goal of treatment is to stop acute bleeding as soon as possible, and treat varices with
medicines and medical procedures. Bleeding must be controlled quickly to preventshockanddeath.
If massive bleeding occurs, the patient may be placed on a ventilator to protect the airways andprevent blood from going down into the lungs.
Treatments for acute bleeding:
A small lighted tube called anendoscope may be used. The health care provider may injectthe varices directly with a clotting medicine, or place a rubber band around the bleedingveins.
A medication that tightens blood vessels (vasoconstriction) may be used. Examples includeoctreotide orvasopressin.
A tube may be inserted through the nose into the stomach and inflated with air. Thisproduces pressure against the bleeding veins (balloon tamponade).
Once the bleeding is stopped, varices can be treated with medicines and medical procedures toprevent future bleeding:
Drugs called beta blockers, such as propranolol and nadolol, are used to reduce the risk ofbleeding.
A small lighted tube called an endoscope may be used to place a rubber band around thebleeding veins.
Transjugular intrahepatic portosystemic shunt (TIPS) is a procedure to create newconnections between two blood vessels in your liver. This can decrease pressure in the
veins and prevent bleeding episodes from happening again.
Emergency surgery may be used (rarely) to treat patients if other therapy fails. Portocaval shunts orsurgery to remove the esophagus are two treatment options, but these procedures are risky.
Patients with bleeding varices from liver disease may need additional treatment of their liverdisease, including a liver transplant.
Outlook (Prognosis)
Bleeding often comes back without treatment. Bleeding esophageal varices are a seriouscomplication of liver disease and have a poor outcome.
Possible Complications
Encephalopathy (sometimes called hepatic encephalopathy)
Esophageal stricture after surgery or endoscopic therapy
Hypovolemic shock
Infection (pneumonia, bloodstream infection,peritonitis)
Return of bleeding after treatment
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When to Contact a Medical Professional
Call your health care provider or go to an emergency room if you vomit blood or have black tarrystools.
Prevention
Treating the causes of liver disease may prevent bleeding. Preventive treatment of varices withmedications such as beta blockers or with endoscopic banding may help prevent bleeding. Livertransplantation should be considered for some patients.
References
Garcia-Tsao G, Sanyal AJ, Grace ND, Carey WD; Practice Guidelines Committee of AmericanAssociation for Study of Liver Diseases; Practice Parameters Committee of American College ofGastroenterology. Prevention and management of gastroesophageal varices and varicealhemorrhage in cirrhosis.Am J Gastroenterol. 2007;102:2086-2102.
Garcia-Tsao G. Cirrhosis and its sequellae. In: Goldman L, Ausiello D, eds.Cecil Medicine. 23rded. Philadelphia, Pa: Saunders Elsevier; 2007:chap 157.