Biochemistry of LipidsBiochemistry and Molecular Biology

Fatty Acids

Fatty Acids

Fatty Acids

C1C16

e.g. oleic Acid is abbreviated as 18:1D9

e.g. palmitic Acid is abbreviated as 16:0

Fatty Acids

Lauric Acid

MW: 200solubility in H2O: 0.063 mg g-1

(solubility in benzene: 2.60 mg g-1)

Glucose

MW: 180solubility in H2O: 1,100 mg g-1

Fatty AcidsSome FAs and their common names…

14:0  myristic acid 16:0 palmitic acid 18:0  stearic acid 18:1 cis9 oleic acid18:2 cis9,12 linoleic acid18:3 cis9,12,15 -linonenic acid 20:4 cis5,8,11,14 arachidonic acid20:5 cis5,8,11,14,17 eicosapentaenoic acid

Oleic Acid

Fatty Acids

Linoleic acidLinolenic acid

Fatty Acids

e.g. Fatty Acid Melting Point (oC)

12:0 44.214:0 53.916:0 63.118:0 69.818:1 13.418:2(9,12) 1.518:3(9,12,15) - 11.0

Fatty Acids

Isomerism

C C

H

H

C C

H H

Cl

Cl Cl

Trans or E

Cis or Z

Cl

Fatty Acids

Triacylglycerides

Glycerol

alcohol carboxylic acid ester

Triacylglycerides

Triacylglycerides

Glycerol

Fatty Acid

Ester Link

Triacylglycerides

Diglyceride

Triglycerides

G

FA1

FA2

G

FA1

FA2

FA3

Triacylglycerides

Triglycerides

Triglycerides

Adipocytes

Triglycerides

Triglycerides

Energy from fat

Phospholipids

The four phosphlipids

Cholesterol

Fluid Mosaic Model

Fat in the blood

Vitamins